age at least 18 Years
Item
Age at least 18 Years
boolean
C0001779 (UMLS CUI 2011AA)
397669002 (SNOMED CT 2011_0131)
Immunocompetent patient.
Item
Immunocompetent
boolean
C1512656 (UMLS CUI 2011AA)
A study treatment area must be identifiable: Minimum of 5 and maximum of 10 typical visible AKs in one contiguous area of up to 50 cm2 on the face or scalp. The eyelids, the inside of the nostrils or ears, or the lip area inside the vermilion border must not be part of this area.
Item
A study treatment area must be identifiable: Minimum of 5 and maximum of 10 typical visible AKs in one contiguous area of up to 50 cm2 on the face or scalp. The eyelids, the inside of the nostrils or ears, or the lip area inside the vermilion border must not be part of this area.
boolean
C0039798 (UMLS CUI 2011AA)
C0205146 (UMLS CUI 2011AA)
42798000 (SNOMED CT 2011_0131)
MTHU009059 (LOINC Version 232)
C0022602 (UMLS CUI 2011AA)
201101007 (SNOMED CT 2011_0131)
10000614 (MedDRA 14.1)
L57.0 (ICD-10-CM Version 2010)
702.0 (ICD-9-CM Version 2011)
C0011900 (UMLS CUI 2011AA)
439401001 (SNOMED CT 2011_0131)
MTHU008876 (LOINC Version 232)
C1274600 (UMLS CUI 2011AA)
403204001 (SNOMED CT 2011_0131)
C1274599 (UMLS CUI 2011AA)
403203007 (SNOMED CT 2011_0131)
A positive histological finding for AK grade I or II (see Section 7.1.1.2). This will be determined from the most suspicious lesion in the STA and there from the most pathological area biopsied during screening visit. This analysis will be done by the central histopathological laboratory.
Item
A positive histological finding for AK grade I or II (see Section 7.1.1.2). This will be determined from the most suspicious lesion in the STA and there from the most pathological area biopsied during screening visit. This analysis will be done by the central histopathological laboratory.
boolean
C0022602 (UMLS CUI 2011AA)
201101007 (SNOMED CT 2011_0131)
10000614 (MedDRA 14.1)
L57.0 (ICD-10-CM Version 2010)
702.0 (ICD-9-CM Version 2011)
C0919553 (UMLS CUI 2011AA)
371469007 (SNOMED CT 2011_0131)
C0221198 (UMLS CUI 2011AA)
49755003 (SNOMED CT 2011_0131)
C2828392 (UMLS CUI 2011AA)
C0006826 (UMLS CUI 2011AA)
363346000 (SNOMED CT 2011_0131)
10028997 (MedDRA 14.1)
MTHU010328 (LOINC Version 232)
C00-C96 (ICD-10-CM Version 2010)
C0205146 (UMLS CUI 2011AA)
42798000 (SNOMED CT 2011_0131)
MTHU009059 (LOINC Version 232)
Willingness to comply with the obligations of the study.
Item
Willingness to comply with the obligations of the study.
boolean
C0600109 (UMLS CUI 2011AA)
225466006 (SNOMED CT 2011_0131)
C1321605 (UMLS CUI 2011AA)
405078008 (SNOMED CT 2011_0131)
C0008976 (UMLS CUI 2011AA)
110465008 (SNOMED CT 2011_0131)
C1514873 (UMLS CUI 2011AA)
History of allergic reaction to imiquimod, diclofenac, acetyl salicylic acid, other non steroidal anti-inflammatory drugs (NSAID), hyaluronic acid, or relevant excipients.
Item
History of allergic reaction to imiquimod, diclofenac, acetyl salicylic acid, other non steroidal anti-inflammatory drugs (NSAID), hyaluronic acid, or relevant excipients.
boolean
C0489531 (UMLS CUI 2011AA)
MTHU001065 (LOINC Version 232)
C0718327 (UMLS CUI 2011AA)
386941002 (SNOMED CT 2011_0131)
C0012091 (UMLS CUI 2011AA)
7034005 (SNOMED CT 2011_0131)
MTHU024758 (LOINC Version 232)
C0004057 (UMLS CUI 2011AA)
7947003 (SNOMED CT 2011_0131)
C0003211 (UMLS CUI 2011AA)
16403005, 372665008 (SNOMED CT 2011_0131)
C0813622 (UMLS CUI 2011AA)
38218009 (SNOMED CT 2011_0131)
MTHU003533 (LOINC Version 232)
C0015237 (UMLS CUI 2011AA)
360215002 (SNOMED CT 2011_0131)
Pregnancy, breast-feeding or planned pregnancy during the study. Women of child bearing potential not using a highly effective method of birth control defined as those which result in a low failure rate (i.e. <1% per year) when used consistently and correctly such as implants, injectables, combined oral contraceptives, hormonal IUDs, tubal ligation or vasectomised partner.
Item
Pregnancy, breast-feeding or planned pregnancy during the study. Women of child bearing potential not using a highly effective method of birth control defined as those which result in a low failure rate (i.e. <1% per year) when used consistently and correctly such as implants, injectables, combined oral contraceptives, hormonal IUDs, tubal ligation or vasectomised partner.
boolean
C0032961 (UMLS CUI 2011AA)
289908002 (SNOMED CT 2011_0131)
10036556 (MedDRA 14.1)
MTHU035048 (LOINC Version 232)
C0006147 (UMLS CUI 2011AA)
10006247 (MedDRA 14.1)
C0032992 (UMLS CUI 2011AA)
169565003 (SNOMED CT 2011_0131)
C0043210 (UMLS CUI 2011AA)
224526002 (SNOMED CT 2011_0131)
C1148523 (UMLS CUI 2011AA)
C0237399 (UMLS CUI 2011AA)
C0420844 (UMLS CUI 2011AA)
169450001 (SNOMED CT 2011_0131)
CL424925 (UMLS CUI 2011AA)
C1262153 (UMLS CUI 2011AA)
10062577 (MedDRA 14.1)
C0457572 (UMLS CUI 2011AA)
268458002 (SNOMED CT 2011_0131)
C0458083 (UMLS CUI 2011AA)
278994005 (SNOMED CT 2011_0131)
C0021900 (UMLS CUI 2011AA)
268460000 (SNOMED CT 2011_0131)
10022745 (MedDRA 14.1)
C0520483 (UMLS CUI 2011AA)
77543007 (SNOMED CT 2011_0131)
10044722 (MedDRA 14.1)
C0420842 (UMLS CUI 2011AA)
268457007 (SNOMED CT 2011_0131)
Presence of AK lesions in the STA with clinically marked hyperkeratosis or hypertrophy as seen in cutaneous horns.
Item
Presence of AK lesions in the STA with clinically marked hyperkeratosis or hypertrophy as seen in cutaneous horns.
boolean
C0022602 (UMLS CUI 2011AA)
201101007 (SNOMED CT 2011_0131)
10000614 (MedDRA 14.1)
L57.0 (ICD-10-CM Version 2010)
702.0 (ICD-9-CM Version 2011)
C0221198 (UMLS CUI 2011AA)
49755003 (SNOMED CT 2011_0131)
C2828392 (UMLS CUI 2011AA)
C0006826 (UMLS CUI 2011AA)
363346000 (SNOMED CT 2011_0131)
10028997 (MedDRA 14.1)
MTHU010328 (LOINC Version 232)
C00-C96 (ICD-10-CM Version 2010)
C0205146 (UMLS CUI 2011AA)
42798000 (SNOMED CT 2011_0131)
MTHU009059 (LOINC Version 232)
C0870082 (UMLS CUI 2011AA)
396228006 (SNOMED CT 2011_0131)
10020649 (MedDRA 14.1)
C0020564 (UMLS CUI 2011AA)
56246009 (SNOMED CT 2011_0131)
10020880 (MedDRA 14.1)
MTHU024506 (LOINC Version 232)
C0085664 (UMLS CUI 2011AA)
403871001 (SNOMED CT 2011_0131)
10011666 (MedDRA 14.1)
L85.8 (ICD-10-CM Version 2010)
Any topical AK treatment including imiquimod or diclofenac, or any systemic AK treatment such as systemic retinoids, or any surgical AK treatment at the STA within the last 2 months prior to randomisation.
Item
Any topical AK treatment including imiquimod or diclofenac, or any systemic AK treatment such as systemic retinoids, or any surgical AK treatment at the STA within the last 2 months prior to randomisation.
boolean
C0022602 (UMLS CUI 2011AA)
201101007 (SNOMED CT 2011_0131)
10000614 (MedDRA 14.1)
L57.0 (ICD-10-CM Version 2010)
702.0 (ICD-9-CM Version 2011)
C0150349 (UMLS CUI 2011AA)
386439008 (SNOMED CT 2011_0131)
C0718327 (UMLS CUI 2011AA)
386941002 (SNOMED CT 2011_0131)
C0012091 (UMLS CUI 2011AA)
7034005 (SNOMED CT 2011_0131)
MTHU024758 (LOINC Version 232)
C1515119 (UMLS CUI 2011AA)
C2267033 (UMLS CUI 2011AA)
C0543467 (UMLS CUI 2011AA)
83578000 (SNOMED CT 2011_0131)
10051332 (MedDRA 14.1)
MTHU000079 (LOINC Version 232)
C2828392 (UMLS CUI 2011AA)
C0006826 (UMLS CUI 2011AA)
363346000 (SNOMED CT 2011_0131)
10028997 (MedDRA 14.1)
MTHU010328 (LOINC Version 232)
C00-C96 (ICD-10-CM Version 2010)
C0205146 (UMLS CUI 2011AA)
42798000 (SNOMED CT 2011_0131)
MTHU009059 (LOINC Version 232)
Persisting AK lesion at screening visit following topical treatment with imiquimod or diclofenac in the STA.
Item
Persisting AK lesion at screening visit following topical treatment with imiquimod or diclofenac in the STA.
boolean
C0022602 (UMLS CUI 2011AA)
201101007 (SNOMED CT 2011_0131)
10000614 (MedDRA 14.1)
L57.0 (ICD-10-CM Version 2010)
702.0 (ICD-9-CM Version 2011)
C0221198 (UMLS CUI 2011AA)
49755003 (SNOMED CT 2011_0131)
C0332282 (UMLS CUI 2011AA)
255260001 (SNOMED CT 2011_0131)
C0150349 (UMLS CUI 2011AA)
386439008 (SNOMED CT 2011_0131)
C0718327 (UMLS CUI 2011AA)
386941002 (SNOMED CT 2011_0131)
C0012091 (UMLS CUI 2011AA)
7034005 (SNOMED CT 2011_0131)
MTHU024758 (LOINC Version 232)
C2828392 (UMLS CUI 2011AA)
C0006826 (UMLS CUI 2011AA)
363346000 (SNOMED CT 2011_0131)
10028997 (MedDRA 14.1)
MTHU010328 (LOINC Version 232)
C00-C96 (ICD-10-CM Version 2010)
C0205146 (UMLS CUI 2011AA)
42798000 (SNOMED CT 2011_0131)
MTHU009059 (LOINC Version 232)
Topical treatment with imiquimod or diclofenac anywhere else on the body within the last 2 months prior to randomisation.
Item
Topical treatment with imiquimod or diclofenac anywhere else on the body within the last 2 months prior to randomisation.
boolean
C0150349 (UMLS CUI 2011AA)
386439008 (SNOMED CT 2011_0131)
C0718327 (UMLS CUI 2011AA)
386941002 (SNOMED CT 2011_0131)
C0012091 (UMLS CUI 2011AA)
7034005 (SNOMED CT 2011_0131)
MTHU024758 (LOINC Version 232)
C1268086 (UMLS CUI 2011AA)
123037004 (SNOMED CT 2011_0131)
C1518422 (UMLS CUI 2011AA)
C2828392 (UMLS CUI 2011AA)
C0006826 (UMLS CUI 2011AA)
363346000 (SNOMED CT 2011_0131)
10028997 (MedDRA 14.1)
MTHU010328 (LOINC Version 232)
C00-C96 (ICD-10-CM Version 2010)
C0205146 (UMLS CUI 2011AA)
42798000 (SNOMED CT 2011_0131)
MTHU009059 (LOINC Version 232)
Presence of any histologically confirmed skin tumour in the STA: in situ SCC including Bowen's disease, invasive SCC, basal cell carcinoma, or other malignant tumours.
Item
Presence of any histologically confirmed skin tumour in the STA: in situ SCC including Bowen's disease, invasive SCC, basal cell carcinoma, or other malignant tumours.
boolean
C0037286 (UMLS CUI 2011AA)
126488004 (SNOMED CT 2011_0131)
10029098 (MedDRA 14.1)
C2828392 (UMLS CUI 2011AA)
C0006826 (UMLS CUI 2011AA)
363346000 (SNOMED CT 2011_0131)
10028997 (MedDRA 14.1)
MTHU010328 (LOINC Version 232)
C00-C96 (ICD-10-CM Version 2010)
C0205146 (UMLS CUI 2011AA)
42798000 (SNOMED CT 2011_0131)
MTHU009059 (LOINC Version 232)
C0444498 (UMLS CUI 2011AA)
264031007 (SNOMED CT 2011_0131)
C0007137 (UMLS CUI 2011AA)
28899001 (SNOMED CT 2011_0131)
10041823 (MedDRA 14.1)
C0006079 (UMLS CUI 2011AA)
84999002 (SNOMED CT 2011_0131)
10006059 (MedDRA 14.1)
D00-D09 (ICD-10-CM Version 2010)
C0205281 (UMLS CUI 2011AA)
10179008 (SNOMED CT 2011_0131)
C0007137 (UMLS CUI 2011AA)
28899001 (SNOMED CT 2011_0131)
10041823 (MedDRA 14.1)
C0007117 (UMLS CUI 2011AA)
1338007 (SNOMED CT 2011_0131)
10004146 (MedDRA 14.1)
C0006826 (UMLS CUI 2011AA)
363346000 (SNOMED CT 2011_0131)
10028997 (MedDRA 14.1)
MTHU010328 (LOINC Version 232)
C00-C96 (ICD-10-CM Version 2010)
Any dermatological disease or condition that may exacerbate by treatment with imiquimod or diclofenac (e.g. rosacea, psoriasis, atopic dermatitis).
Item
Any dermatological disease or condition that may exacerbate by treatment with imiquimod or diclofenac (e.g. rosacea, psoriasis, atopic dermatitis).
boolean
C0037274 (UMLS CUI 2011AA)
95320005 (SNOMED CT 2011_0131)
10048768, 10040831 (MedDRA 14.1)
MTHU031899 (LOINC Version 232)
C1444749 (UMLS CUI 2011AA)
410661009 (SNOMED CT 2011_0131)
C0039798 (UMLS CUI 2011AA)
C0718327 (UMLS CUI 2011AA)
386941002 (SNOMED CT 2011_0131)
C0012091 (UMLS CUI 2011AA)
7034005 (SNOMED CT 2011_0131)
MTHU024758 (LOINC Version 232)
C0035854 (UMLS CUI 2011AA)
398909004 (SNOMED CT 2011_0131)
10039218 (MedDRA 14.1)
L71.9 (ICD-10-CM Version 2010)
695.3 (ICD-9-CM Version 2011)
C0033860 (UMLS CUI 2011AA)
9014002 (SNOMED CT 2011_0131)
10037153 (MedDRA 14.1)
L40 (ICD-10-CM Version 2010)
C0011615 (UMLS CUI 2011AA)
24079001 (SNOMED CT 2011_0131)
10012438 (MedDRA 14.1)
L20.9 (ICD-10-CM Version 2010)
Any dermatological disease or condition in the STA that causes difficulty with examination (e.g. eczema).
Item
Any dermatological disease or condition in the STA that causes difficulty with examination (e.g. eczema).
boolean
C0037274 (UMLS CUI 2011AA)
95320005 (SNOMED CT 2011_0131)
10048768, 10040831 (MedDRA 14.1)
MTHU031899 (LOINC Version 232)
C2828392 (UMLS CUI 2011AA)
C0006826 (UMLS CUI 2011AA)
363346000 (SNOMED CT 2011_0131)
10028997 (MedDRA 14.1)
MTHU010328 (LOINC Version 232)
C00-C96 (ICD-10-CM Version 2010)
C0205146 (UMLS CUI 2011AA)
42798000 (SNOMED CT 2011_0131)
MTHU009059 (LOINC Version 232)
C0678227 (UMLS CUI 2011AA)
23981006 (SNOMED CT 2011_0131)
C1299586 (UMLS CUI 2011AA)
52925006 (SNOMED CT 2011_0131)
C0582103 (UMLS CUI 2011AA)
225886003 (SNOMED CT 2011_0131)
C0013595 (UMLS CUI 2011AA)
43116000 (SNOMED CT 2011_0131)
10014184 (MedDRA 14.1)
L30.9 (ICD-10-CM Version 2010)
Systemic immunomodulatory treatment such as interferon, azathioprine, cyclosporine, retinoids, any oral or injectable corticosteroids, or inhaled or nasal corticosteroids with dosages of >1200 µg/day beclomethasone or equivalent within 4 weeks before start of study treatment.
Item
Systemic immunomodulatory treatment such as interferon, azathioprine, cyclosporine, retinoids, any oral or injectable corticosteroids, or inhaled or nasal corticosteroids with dosages of >1200 µg/day beclomethasone or equivalent within 4 weeks before start of study treatment.
boolean
C0205373 (UMLS CUI 2011AA)
31099001 (SNOMED CT 2011_0131)
CL412323 (UMLS CUI 2011AA)
C0021747 (UMLS CUI 2011AA)
49327004 (SNOMED CT 2011_0131)
MTHU021353 (LOINC Version 232)
C0004482 (UMLS CUI 2011AA)
372574004 (SNOMED CT 2011_0131)
MTHU006794 (LOINC Version 232)
C0010592 (UMLS CUI 2011AA)
387467008 (SNOMED CT 2011_0131)
MTHU005140 (LOINC Version 232)
C2267033 (UMLS CUI 2011AA)
C0001617 (UMLS CUI 2011AA)
79440004 (SNOMED CT 2011_0131)
C0004905 (UMLS CUI 2011AA)
116574000 (SNOMED CT 2011_0131)
History of any malignant tumour with high tumour burden or any systemic antitumour treatment (incl. radiotherapy).
Item
History of any malignant tumour with high tumour burden or any systemic antitumour treatment (incl. radiotherapy).
boolean
C2735088 (UMLS CUI 2011AA)
MTHU034770 (LOINC Version 232)
C0205373 (UMLS CUI 2011AA)
31099001 (SNOMED CT 2011_0131)
C0920425 (UMLS CUI 2011AA)
C0034619 (UMLS CUI 2011AA)
History of any malignant skin tumour having metastasised or where metastasis could be expected.
Item
History of any malignant skin tumour having metastasised or where metastasis could be expected.
boolean
CL421546 (UMLS CUI 2011AA)
392521001 (SNOMED CT 2011_0131)
C0007114 (UMLS CUI 2011AA)
372130007 (SNOMED CT 2011_0131)
10040808 (MedDRA 14.1)
C44.9 (ICD-10-CM Version 2010)
C0027627 (UMLS CUI 2011AA)
128462008 (SNOMED CT 2011_0131)
10027449 (MedDRA 14.1)
C1517001 (UMLS CUI 2011AA)
History of severe cardiovascular, pulmonary, hepatic, renal, gastrointestinal, haematological, endocrine, metabolic, mental, neurological, or other disease within the last two years.
Item
History of severe cardiovascular, pulmonary, hepatic, renal, gastrointestinal, haematological, endocrine, metabolic, mental, neurological, or other disease within the last two years.
boolean
CL421546 (UMLS CUI 2011AA)
392521001 (SNOMED CT 2011_0131)
C0007222 (UMLS CUI 2011AA)
105980002 (SNOMED CT 2011_0131)
10007649 (MedDRA 14.1)
429.2 (ICD-9-CM Version 2011)
C0024115 (UMLS CUI 2011AA)
19829001 (SNOMED CT 2011_0131)
10025082 (MedDRA 14.1)
J98.4 (ICD-10-CM Version 2010)
C0023895 (UMLS CUI 2011AA)
235856003 (SNOMED CT 2011_0131)
10024670 (MedDRA 14.1)
K76.9 (ICD-10-CM Version 2010)
573.9 (ICD-9-CM Version 2011)
C0022658 (UMLS CUI 2011AA)
90708001 (SNOMED CT 2011_0131)
10029151 (MedDRA 14.1)
N18.9 (ICD-10-CM Version 2010)
C0017178 (UMLS CUI 2011AA)
119292006 (SNOMED CT 2011_0131)
10017944 (MedDRA 14.1)
C0018939 (UMLS CUI 2011AA)
191124002 (SNOMED CT 2011_0131)
10061590 (MedDRA 14.1)
D75.9 (ICD-10-CM Version 2010)
289.9 (ICD-9-CM Version 2011)
C0014130 (UMLS CUI 2011AA)
362969004 (SNOMED CT 2011_0131)
10014695 (MedDRA 14.1)
MTHU021570 (LOINC Version 232)
E34.9 (ICD-10-CM Version 2010)
259.9 (ICD-9-CM Version 2011)
C0025517 (UMLS CUI 2011AA)
30390004 (SNOMED CT 2011_0131)
10058097 (MedDRA 14.1)
E88.9 (ICD-10-CM Version 2010)
277.9 (ICD-9-CM Version 2011)
C0004936 (UMLS CUI 2011AA)
74732009 (SNOMED CT 2011_0131)
10037174 (MedDRA 14.1)
F99 (ICD-10-CM Version 2010)
290-319.99 (ICD-9-CM Version 2011)
C0027765 (UMLS CUI 2011AA)
118940003 (SNOMED CT 2011_0131)
10029202 (MedDRA 14.1)
G98.8 (ICD-10-CM Version 2010)
349.9 (ICD-9-CM Version 2011)
C0012634 (UMLS CUI 2011AA)
64572001 (SNOMED CT 2011_0131)
Mentally incapacitated patient.
Item
Mentally Disabled Persons
boolean
C0079822 (UMLS CUI 2011AA)
Present or history of drug or alcohol abuse within the last 3 years.
Item
Present or history of drug or alcohol abuse within the last 3 years.
boolean
C0013146 (UMLS CUI 2011AA)
26416006 (SNOMED CT 2011_0131)
10013654 (MedDRA 14.1)
LP36310-8 (LOINC Version 232)
305.90 (ICD-9-CM Version 2011)
C0085762 (UMLS CUI 2011AA)
15167005 (SNOMED CT 2011_0131)
10001584 (MedDRA 14.1)
LP36309-0 (LOINC Version 232)
F10.1 (ICD-10-CM Version 2010)
305.0 (ICD-9-CM Version 2011)
C1299544 (UMLS CUI 2011AA)
371435006 (SNOMED CT 2011_0131)
C0221628 (UMLS CUI 2011AA)
371434005 (SNOMED CT 2011_0131)
Exposure to an investigational product within the last 3 months.
Item
Exposure to an investigational product within the last 3 months.
boolean
C0332157 (UMLS CUI 2011AA)
24932003 (SNOMED CT 2011_0131)
C0013230 (UMLS CUI 2011AA)
C1517741 (UMLS CUI 2011AA)
C0205449 (UMLS CUI 2011AA)
421291004 (SNOMED CT 2011_0131)
C0439231 (UMLS CUI 2011AA)
258706009 (SNOMED CT 2011_0131)
MO (HL7 V3 2006_05)
Lack of ability or willingness to give informed consent.
Item
Lack of ability or willingness to give informed consent.
boolean
C0021430 (UMLS CUI 2011AA)
Age below 18 years.
Item
Age below 18 years.
boolean
C0001779 (UMLS CUI 2011AA)
397669002 (SNOMED CT 2011_0131)
Lack of willingness to have personal study related data collected, archived or transmitted according to protocol.
Item
Lack of willingness to have personal study related data collected, archived or transmitted according to protocol.
boolean
C0332197 (UMLS CUI 2011AA)
2667000 (SNOMED CT 2011_0131)
C0600109 (UMLS CUI 2011AA)
225466006 (SNOMED CT 2011_0131)
C1709695 (UMLS CUI 2011AA)
C0681884 (UMLS CUI 2011AA)
C0681873 (UMLS CUI 2011AA)
C0525058 (UMLS CUI 2011AA)
Anticipated non-availability for study visits/procedures.
Item
Anticipated non-availability for study visits/procedures.
boolean
C0679106 (UMLS CUI 2011AA)
C0686905 (UMLS CUI 2011AA)
397854000 (SNOMED CT 2011_0131)
C0008976 (UMLS CUI 2011AA)
110465008 (SNOMED CT 2011_0131)
C1554196 (UMLS CUI 2011AA)
ENC (HL7 V3 2006_05)
C0680734 (UMLS CUI 2011AA)
Vulnerable subjects (such as persons kept in detention).
Item
Vulnerable subjects (such as persons kept in detention).
boolean
C1562367 (UMLS CUI 2011AA)
417430008 (SNOMED CT 2011_0131)
C0680725 (UMLS CUI 2011AA)