Elig.phs001058.v1.p1.1
Item
We performed a nested case-control experiment for incident cardiovascular events. Cardiovascular events are defined as myocardial infarction, coronary revascularization, or stroke. We included participants who passed the following sample quality control measures: contamination < 5%, missingness < 5%, concordance with genome-wide array data when available, and Ti/Tv, total variants / depth, and F inbreeding coefficient outliers. We also excluded individuals who were genotypically found to be within three degrees of relatedness.
boolean
C0027775 (UMLS CUI [1,1])
C1551358 (UMLS CUI [1,2])
C1320716 (UMLS CUI [1,3])
C1704788 (UMLS CUI [1,4])
C0027051 (UMLS CUI [1,5])
C0038454 (UMLS CUI [1,6])
C0877341 (UMLS CUI [1,7])
C1512693 (UMLS CUI [1,8])
C2347026 (UMLS CUI [1,9])
C0034378 (UMLS CUI [1,10])
C2349974 (UMLS CUI [1,11])
C4553529 (UMLS CUI [1,12])
C0017428 (UMLS CUI [1,13])
C1510941 (UMLS CUI [1,14])
C1511726 (UMLS CUI [1,15])
C0456603 (UMLS CUI [1,16])
C0439810 (UMLS CUI [1,17])
C0205419 (UMLS CUI [1,18])
C0205125 (UMLS CUI [1,19])
C0681921 (UMLS CUI [1,20])
C3846158 (UMLS CUI [1,21])
C0680251 (UMLS CUI [2,1])
C0017431 (UMLS CUI [2,2])
C0205396 (UMLS CUI [2,3])
C3639750 (UMLS CUI [2,4])
Elig.phs001058.v1.p1.2
Item
Cases include those who developed cardiovascular events after a median follow-up of 2.7 years. We excluded individuals who had clinical cardiovascular disease at baseline examination. Controls were matched to each case in the matched nested case-control experiment. Controls were matched for age (+/- 2 years), sex, smoking status, and type 2 diabetes status.
boolean
C1698493 (UMLS CUI [1,1])
C1320716 (UMLS CUI [1,2])
C2939193 (UMLS CUI [1,3])
C0449238 (UMLS CUI [1,4])
C1522577 (UMLS CUI [1,5])
C0680251 (UMLS CUI [1,6])
C0007222 (UMLS CUI [1,7])
C1442488 (UMLS CUI [1,8])
C0031809 (UMLS CUI [1,9])
C0009932 (UMLS CUI [1,10])
C1708943 (UMLS CUI [1,11])
C0027775 (UMLS CUI [1,12])
C0001779 (UMLS CUI [1,13])
C0079399 (UMLS CUI [1,14])
C1519386 (UMLS CUI [1,15])
C0011860 (UMLS CUI [1,16])