English

This subject phenotype table includes subject ID, age at diagnosis, number of APC mutation in APC zones 1-4, APC biallelic loss, patients grouped by 4 gene mutations or classed by different types of APC and other gene mutations, CMS (consensus molecular subtypes) group used the SSP (single sample predictor) method, primary tumor location in colon, primary tumor located site in colon, MSI (microsatellite instability) high status, tumor metastatic, colon cancer standard diagnostic stage, patients vital status and overall survival time, EMT signature scores, RAS downstream signature scores, expression mean of 64 beta-catenin targeted genes, and APC mRNA expression.

5 forms  
pht005498
Description

pht005498

Alias
UMLS CUI [1,1]
C3846158
De-identified Subject ID
Description

Subject_ID

Data type

string

Alias
UMLS CUI [1,1]
C4684638
UMLS CUI [1,2]
C2348585
Age at Diagnosis
Description

Age

Data type

text

Measurement units
  • years
Alias
UMLS CUI [1,1]
C1828181
Number of APC mutation in APC zone 1 and 2
Description

APC_Zone1_2

Data type

text

Alias
UMLS CUI [1,1]
C4522286
UMLS CUI [1,2]
C1265611
Number of APC mutation in APC zone 3 and 4
Description

APC_Zone3_4

Data type

text

Alias
UMLS CUI [1,1]
C4522286
UMLS CUI [1,2]
C1265611
APC biallelic loss
Description

APC_allelic_loss

Data type

text

Alias
UMLS CUI [1,1]
C0162832
UMLS CUI [1,2]
C4329454
Patients grouped by 4 gene mutations
Description

Group

Data type

string

Alias
UMLS CUI [1,1]
C0026882
UMLS CUI [1,2]
C0441833
Patients classed by different types of APC and other gene mutations
Description

Classes

Data type

string

Alias
UMLS CUI [1,1]
C0008902
UMLS CUI [1,2]
C0332307
UMLS CUI [1,3]
C4522286
UMLS CUI [1,4]
C0205394
UMLS CUI [1,5]
C0026882
CMS group used the SSP method
Description

CMS_combined_group

Data type

string

Alias
UMLS CUI [1,1]
C1257890
UMLS CUI [1,2]
C3846158
Primary tumor location in colon
Description

Tumor_Location

Data type

string

Alias
UMLS CUI [1,1]
C0475447
Primary tumor located site in colon
Description

Tumor_site

Data type

string

Alias
UMLS CUI [1,1]
C0449695
MSI high status
Description

MSI_H_status

Data type

string

Alias
UMLS CUI [1,1]
C4523846
UMLS CUI [1,2]
C0449438
Tumor metastatic
Description

Distant_metastasis

Data type

string

Alias
UMLS CUI [1,1]
C2939420
Colon cancer standard diagnostic stage
Description

Stage

Data type

string

Alias
UMLS CUI [1,1]
C0699790
UMLS CUI [1,2]
C0027646
Patients vital status
Description

Vital_Status

Data type

string

Alias
UMLS CUI [1,1]
C1148433
Patients overall survival time
Description

Overall_Survival_Time

Data type

float

Measurement units
  • months
Alias
UMLS CUI [1,1]
C1561607
UMLS CUI [1,2]
C2919552
months
EMT signature scores
Description

EMT_signature_scores

Data type

float

Alias
UMLS CUI [1,1]
C3846158
UMLS CUI [1,2]
C1519316
UMLS CUI [1,3]
C0449820
RAS downstream signature scores
Description

Ras_AZ_signature_scores

Data type

float

Alias
UMLS CUI [1,1]
C0034678
UMLS CUI [1,2]
C0522506
UMLS CUI [1,3]
C1519316
UMLS CUI [1,4]
C0449820
Expression mean of 64 beta-catenin targeted genes
Description

Beta_catenin_targeted_genes_scores

Data type

float

Alias
UMLS CUI [1,1]
C0017262
UMLS CUI [1,2]
C0444504
UMLS CUI [1,3]
C0105770
UMLS CUI [1,4]
C1521840
UMLS CUI [1,5]
C0017337
APC mRNA expression
Description

APC_mRNA_expression

Data type

float

Alias
UMLS CUI [1,1]
C0162832
UMLS CUI [1,2]
C1515670
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Similar models

This subject phenotype table includes subject ID, age at diagnosis, number of APC mutation in APC zones 1-4, APC biallelic loss, patients grouped by 4 gene mutations or classed by different types of APC and other gene mutations, CMS (consensus molecular subtypes) group used the SSP (single sample predictor) method, primary tumor location in colon, primary tumor located site in colon, MSI (microsatellite instability) high status, tumor metastatic, colon cancer standard diagnostic stage, patients vital status and overall survival time, EMT signature scores, RAS downstream signature scores, expression mean of 64 beta-catenin targeted genes, and APC mRNA expression.

5 forms
Name
Type
Description | Question | Decode (Coded Value)
Data type
Alias
Item Group
pht005498
C3846158 (UMLS CUI [1,1])
Subject_ID
Item
De-identified Subject ID
string
C4684638 (UMLS CUI [1,1])
C2348585 (UMLS CUI [1,2])
Item
Age at Diagnosis
text
C1828181 (UMLS CUI [1,1])
Age
Code List
Age at Diagnosis
CL Item
age > 89 years (90+)
APC_Zone1_2
Item
Number of APC mutation in APC zone 1 and 2
text
C4522286 (UMLS CUI [1,1])
C1265611 (UMLS CUI [1,2])
APC_Zone3_4
Item
Number of APC mutation in APC zone 3 and 4
text
C4522286 (UMLS CUI [1,1])
C1265611 (UMLS CUI [1,2])
Item
APC biallelic loss
text
C0162832 (UMLS CUI [1,1])
C4329454 (UMLS CUI [1,2])
APC_allelic_loss
Code List
APC biallelic loss
CL Item
No (0)
CL Item
Yes (1)
Item
Patients grouped by 4 gene mutations
string
C0026882 (UMLS CUI [1,1])
C0441833 (UMLS CUI [1,2])
Group
Code List
Patients grouped by 4 gene mutations
CL Item
Kras mutation only (2)
CL Item
patients with APC mutation including 3 patients with BRAF(V600E) mutation (4)
CL Item
KRAS and TP53 mutations (5)
CL Item
APC and KRAS mutations (6)
CL Item
patients with APC and TP53 mutations including 5 patients with BRAF(V600E) mutation (7)
CL Item
APC,KRAS and TP53 mutations (8)
CL Item
none of the APC,KRAS,TP53 and BRAF genes are mutated (1a)
CL Item
patient with BRAF(V600E) (1b)
CL Item
TP53 mutation only (3a)
CL Item
BRAF and TP53 mutations (3b)
Item
Patients classed by different types of APC and other gene mutations
string
C0008902 (UMLS CUI [1,1])
C0332307 (UMLS CUI [1,2])
C4522286 (UMLS CUI [1,3])
C0205394 (UMLS CUI [1,4])
C0026882 (UMLS CUI [1,5])
Classes
Code List
Patients classed by different types of APC and other gene mutations
CL Item
APCwt (0)
CL Item
APC(1), APC(1)/KRAS, APC(1)/TP53 (1)
CL Item
APC(2), APC(2)/KRAS, APC(2)/TP53 (2)
CL Item
APC(1)/KRAS/TP53 (3)
CL Item
APC(2)/KRAS/TP53 (4)
Item
CMS group used the SSP method
string
C1257890 (UMLS CUI [1,1])
C3846158 (UMLS CUI [1,2])
CMS_combined_group
Code List
CMS group used the SSP method
CL Item
CMS1 (CMS1)
CL Item
CMS2 (CMS2)
CL Item
CMS3 (CMS3)
CL Item
CMS4 (CMS4)
CL Item
Non-consensus (NC)
CL Item
Not done (ND)
Item
Primary tumor location in colon
string
C0475447 (UMLS CUI [1,1])
Tumor_Location
Code List
Primary tumor location in colon
CL Item
missing (Blank)
CL Item
Left (Left)
CL Item
Right (Right)
Item
Primary tumor located site in colon
string
C0449695 (UMLS CUI [1,1])
Tumor_site
Code List
Primary tumor located site in colon
CL Item
Ascend Rt (Ascend Rt)
CL Item
missing (Blank)
CL Item
Cecum (Cecum)
CL Item
Descend Lt (Descend Lt)
CL Item
Rectosigmoid (Rectosig)
CL Item
Rectum (Rectum)
CL Item
Sigmoid (Sigmoid)
CL Item
Transverse (Transverse)
Item
MSI high status
string
C4523846 (UMLS CUI [1,1])
C0449438 (UMLS CUI [1,2])
MSI_H_status
Code List
MSI high status
CL Item
No (No)
CL Item
Yes (Yes)
Item
Tumor metastatic
string
C2939420 (UMLS CUI [1,1])
Distant_metastasis
Code List
Tumor metastatic
CL Item
No (No)
CL Item
Yes (Yes)
Item
Colon cancer standard diagnostic stage
string
C0699790 (UMLS CUI [1,1])
C0027646 (UMLS CUI [1,2])
Stage
Code List
Colon cancer standard diagnostic stage
CL Item
1 (1)
CL Item
2 (2)
CL Item
3 (3)
CL Item
4 (4)
CL Item
missing (.)
Item
Patients vital status
string
C1148433 (UMLS CUI [1,1])
Vital_Status
Code List
Patients vital status
CL Item
Alive (Alive)
CL Item
Dead (Dead)
Overall_Survival_Time
Item
Patients overall survival time
float
C1561607 (UMLS CUI [1,1])
C2919552 (UMLS CUI [1,2])
EMT_signature_scores
Item
EMT signature scores
float
C3846158 (UMLS CUI [1,1])
C1519316 (UMLS CUI [1,2])
C0449820 (UMLS CUI [1,3])
Ras_AZ_signature_scores
Item
RAS downstream signature scores
float
C0034678 (UMLS CUI [1,1])
C0522506 (UMLS CUI [1,2])
C1519316 (UMLS CUI [1,3])
C0449820 (UMLS CUI [1,4])
Beta_catenin_targeted_genes_scores
Item
Expression mean of 64 beta-catenin targeted genes
float
C0017262 (UMLS CUI [1,1])
C0444504 (UMLS CUI [1,2])
C0105770 (UMLS CUI [1,3])
C1521840 (UMLS CUI [1,4])
C0017337 (UMLS CUI [1,5])
APC_mRNA_expression
Item
APC mRNA expression
float
C0162832 (UMLS CUI [1,1])
C1515670 (UMLS CUI [1,2])
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