Elig.phs001163.v1.p1.1
Item
The study will include all parent-offspring trios/quartets selected from the group of approximately 450 trios with offspring born 42 or more weeks after the last significant parental Chernobyl-related exposure. The offspring can be of either sex but must be adult (age >= 18 years at interview); if more than one child is born to a given set of parents, the first and last such eligible siblings will be selected for participation, in the interests of maximizing the variation of time from last exposure to conception, also to maximize the signal (by including offspring closest in time to the exposure, with less likelihood of removal of damaged sperm /oocytes, and by including offspring furthest in time from the exposure, with less likelihood of direct exposure of the child, and maximizing cumulative parental pre-conception gonadal dose). Twins will be especially informative given the comparable exposures in utero and in early life. A high proportion of the trios/quartets currently reside in Kyiv. The majority of these trios/quartets have undergone regular medical examinations as a result of follow-up by the CER. Most of them are expected to be alive.
boolean
C1512693 (UMLS CUI [1,1])
C0030551 (UMLS CUI [1,2])
C0680063 (UMLS CUI [1,3])
C3846158 (UMLS CUI [1,4])
C0242802 (UMLS CUI [1,5])
C0441833 (UMLS CUI [1,6])
C1148523 (UMLS CUI [1,7])
C0040223 (UMLS CUI [1,8])
C0332282 (UMLS CUI [1,9])
C1517741 (UMLS CUI [1,10])
C2985739 (UMLS CUI [1,11])
C0030551 (UMLS CUI [1,12])
C0332157 (UMLS CUI [1,13])
C1449773 (UMLS CUI [1,14])
C1517030 (UMLS CUI [1,15])
C0680063 (UMLS CUI [2,1])
C0079399 (UMLS CUI [2,2])
C0001779 (UMLS CUI [2,3])
C0001675 (UMLS CUI [2,4])
C0439093 (UMLS CUI [3,1])
C0205447 (UMLS CUI [3,2])
C0008059 (UMLS CUI [3,3])
C1705195 (UMLS CUI [3,4])
C0030551 (UMLS CUI [3,5])
C0242802 (UMLS CUI [3,6])
C0205435 (UMLS CUI [3,7])
C1517741 (UMLS CUI [3,8])
C0037047 (UMLS CUI [3,9])
C1302261 (UMLS CUI [3,10])
C0205289 (UMLS CUI [3,11])
C0871362 (UMLS CUI [3,12])
C0041427 (UMLS CUI [4,1])
C2986490 (UMLS CUI [4,2])
C0205163 (UMLS CUI [4,3])
C0332157 (UMLS CUI [4,4])
C1517030 (UMLS CUI [4,5])
C1708480 (UMLS CUI [4,6])
C1279919 (UMLS CUI [4,7])
C0376558 (UMLS CUI [4,8])
C0521116 (UMLS CUI [5,1])
C2316883 (UMLS CUI [5,2])
C0205272 (UMLS CUI [6,1])
C0582103 (UMLS CUI [6,2])
C1274040 (UMLS CUI [6,3])
C1522577 (UMLS CUI [6,4])
C1517001 (UMLS CUI [7,1])
C2584946 (UMLS CUI [7,2])
Elig.phs001163.v1.p1.2
Item
Excluded from the study will be those who cannot be located, those with offspring born within 42 weeks of the last significant Chernobyl-related exposure, those parents or offspring found to have cancer, those who refuse to participate in the study, or who do not provide informed consent.
boolean
C0332196 (UMLS CUI [1,1])
C1299582 (UMLS CUI [1,2])
C0450429 (UMLS CUI [1,3])
C0332196 (UMLS CUI [2,1])
C1148523 (UMLS CUI [2,2])
C0332282 (UMLS CUI [2,3])
C0040223 (UMLS CUI [2,4])
C2985739 (UMLS CUI [2,5])
C0332157 (UMLS CUI [2,6])
C1449773 (UMLS CUI [2,7])
C1517030 (UMLS CUI [2,8])
C0332196 (UMLS CUI [3,1])
C0030551 (UMLS CUI [3,2])
C0680063 (UMLS CUI [3,3])
C0012634 (UMLS CUI [3,4])
C0006826 (UMLS CUI [3,5])
C0332196 (UMLS CUI [4,1])
C1136454 (UMLS CUI [4,2])
C0008976 (UMLS CUI [4,3])
C0332196 (UMLS CUI [5,1])
C0332268 (UMLS CUI [5,2])
C0021430 (UMLS CUI [5,3])