Item Group
Inclusion and exclusion criteria
C1512693 (UMLS CUI [1,1])
C0680251 (UMLS CUI [1,2])
Elig.phs001342.v1.p1.1
Item
Two groups of individuals are included who have severe statin-induced myopathy. Individuals considered as having severe statin-induced myopathy must satisfy all the following criteria: self-reported muscle pain +/- weakness after taking statin and persistent symptoms post-therapy for at least 6 months. The first group is 20 individuals from 8 family groups in which the probands have severe statin-induced myopathy +/- elevated plasma CK. The second group consists of 26 unrelated individuals with severe statin-induced myopathy who have muscle pain and/or weakness attributed solely to statin therapy and plasma creatine kinase (CK) levels > 5 times the upper limit of normal (ULN). Age under 65 when symptoms started.
boolean
C0681850 (UMLS CUI [1,1])
C0205082 (UMLS CUI [1,2])
C3549252 (UMLS CUI [1,3])
C0410220 (UMLS CUI [1,4])
C1512693 (UMLS CUI [2,1])
C0205082 (UMLS CUI [2,2])
C3549252 (UMLS CUI [2,3])
C0410220 (UMLS CUI [2,4])
C2700446 (UMLS CUI [2,5])
C0151786 (UMLS CUI [2,6])
C0231528 (UMLS CUI [2,7])
C0231290 (UMLS CUI [2,8])
C1290952 (UMLS CUI [2,9])
C0360714 (UMLS CUI [2,10])
C0449238 (UMLS CUI [2,11])
C0681850 (UMLS CUI [3,1])
C0015576 (UMLS CUI [3,2])
C0205082 (UMLS CUI [3,3])
C3549252 (UMLS CUI [3,4])
C0410220 (UMLS CUI [3,5])
C1657311 (UMLS CUI [3,6])
C0681850 (UMLS CUI [4,1])
C1546988 (UMLS CUI [4,2])
C0205082 (UMLS CUI [4,3])
C3549252 (UMLS CUI [4,4])
C0410220 (UMLS CUI [4,5])
C0231528 (UMLS CUI [4,6])
C0151786 (UMLS CUI [4,7])
C0596130 (UMLS CUI [4,8])
C1290952 (UMLS CUI [4,9])
C0360714 (UMLS CUI [4,10])
C1657311 (UMLS CUI [4,11])
C0001779 (UMLS CUI [5,1])