Elig.phs000673.v4.p1.1
Item
*5.0 ELIGIBILITY* *5.1 Patient population* This protocol is designed to collect biospecimens with annotated clinical data from patients with advanced or refractory cancer.
boolean
C1516637 (UMLS CUI [1,1])
C1516698 (UMLS CUI [1,2])
C2347026 (UMLS CUI [1,3])
C3645564 (UMLS CUI [1,4])
C1516606 (UMLS CUI [1,5])
C0877373 (UMLS CUI [1,6])
C0677936 (UMLS CUI [1,7])
Elig.phs000673.v4.p1.2
Item
*5.2 5.2 Inclusion Criteria: (Must satisfy all criteria and either #3 or #4)*
boolean
C1512693 (UMLS CUI [1,1])
Elig.phs000673.v4.p1.3
Item
A histologically or cytologically confirmed diagnosis of cancer
boolean
C0679557 (UMLS CUI [1,1])
C0006826 (UMLS CUI [1,2])
C1298647 (UMLS CUI [1,3])
Elig.phs000673.v4.p1.4
Item
Patients with any advanced or refractory malignancy
boolean
C0877373 (UMLS CUI [1,1])
C0677936 (UMLS CUI [1,2])
Elig.phs000673.v4.p1.5
Item
Patients are undergoing standard of care surgeries or procedures where specimens will be first used for routine pathologic assessment and only then will leftover tissue be used for research purposes **OR**
boolean
C2936643 (UMLS CUI [1,1])
C0087111 (UMLS CUI [1,2])
C1524063 (UMLS CUI [1,3])
C2347026 (UMLS CUI [1,4])
C0920316 (UMLS CUI [1,5])
C1317598 (UMLS CUI [1,6])
C0445107 (UMLS CUI [1,7])
C0475358 (UMLS CUI [1,8])
C0242481 (UMLS CUI [1,9])
Elig.phs000673.v4.p1.6
Item
Patients must have tumor suitable for biopsy (as assessed by trained specialists in interventional radiology) and Patients are medically fit to undergo a tissue biopsy or surgical procedure to get tumor tissue *OR* If Patients do not have a tumor suitable for biopsy but have another tissue available for molecular evaluation
boolean
C0475358 (UMLS CUI [1,1])
C1548787 (UMLS CUI [1,2])
C0005558 (UMLS CUI [1,3])
C1299581 (UMLS CUI [1,4])
C4707158 (UMLS CUI [1,5])
C0005558 (UMLS CUI [1,6])
C1298908 (UMLS CUI [2,1])
C0475358 (UMLS CUI [2,2])
C1548787 (UMLS CUI [2,3])
C0005558 (UMLS CUI [2,4])
C0470187 (UMLS CUI [2,5])
C0205394 (UMLS CUI [2,6])
C0040300 (UMLS CUI [2,7])
C1513380 (UMLS CUI [2,8])
Elig.phs000673.v4.p1.7
Item
Older than or equal to 18 years of age
boolean
C0001779 (UMLS CUI [1,1])
Elig.phs000673.v4.p1.8
Item
Procedure-specific signed informed consent prior to initiation of any study-related procedures
boolean
C0021430 (UMLS CUI [1,1])
C5421123 (UMLS CUI [1,2])
Elig.phs000673.v4.p1.9
Item
Women and minorities are included in this protocol
boolean
C1512693 (UMLS CUI [1,1])
C0043210 (UMLS CUI [1,2])
C0026192 (UMLS CUI [1,3])
Elig.phs000673.v4.p1.10
Item
Patients with multiple malignancies remain eligible
boolean
C1512693 (UMLS CUI [1,1])
C0346429 (UMLS CUI [1,2])
Elig.phs000673.v4.p1.11
Item
Patients with an inherited cancer syndrome or a medical history suggestive of an inherited cancer syndrome remain eligible
boolean
C1512693 (UMLS CUI [1,1])
C0019247 (UMLS CUI [1,2])
C0006826 (UMLS CUI [1,3])
C1512693 (UMLS CUI [2,1])
C0262926 (UMLS CUI [2,2])
C0332299 (UMLS CUI [2,3])
C0019247 (UMLS CUI [2,4])
C0006826 (UMLS CUI [2,5])
Elig.phs000673.v4.p1.12
Item
*5.3 Exclusion Criteria: *
boolean
C0680251 (UMLS CUI [1,1])
Elig.phs000673.v4.p1.13
Item
It is the enrolling study physician's discretion to decide if a patient is not fit enough to undergo tissue biopsy
boolean
C0680251 (UMLS CUI [1,1])
C1516879 (UMLS CUI [1,2])
C1710470 (UMLS CUI [1,3])
C0679006 (UMLS CUI [1,4])
C4708589 (UMLS CUI [1,5])
Elig.phs000673.v4.p1.14
Item
Patients who are incarcerated are not eligible to participate
boolean
C0680251 (UMLS CUI [1,1])
C0205255 (UMLS CUI [1,2])
Elig.phs000673.v4.p1.15
Item
Women who are pregnant
boolean
C0680251 (UMLS CUI [1,1])
C0032961 (UMLS CUI [1,2])
Elig.phs000673.v4.p1.16
Item
*5.4 Women of childbearing age* For women of childbearing age, there are no screening requirements. We note that most patients entering this study are seeking eligibility for therapy or other clinical trial, in which case they are generally asked to avoiding becoming pregnant and even exercise some form of contraception by their medical oncologist. For women of childbearing age, their referring medical oncologist will discuss necessity or role for appropriate contraception. This is not part of the study activity, nor is it required for participation.
boolean
C3831118 (UMLS CUI [1,1])
C1298908 (UMLS CUI [1,2])
C0220908 (UMLS CUI [1,3])
C0700589 (UMLS CUI [1,4])