Anglais

The subject phenotypes data table includes gender, race (n=3 variables), ethnicity, European ancestry, affection status for drug-induced liver injury (DILI), age at DILI onset, adjudicated DILI diagnosis, candidate drugs (n=3 variables), causality scores of drugs (n=4 variables), injury type, severity, and peak ALT, bilirubin, and AKP measurements, and R-value at DILI onset.

5 Formulaires  
pht003552
Description

pht003552

Alias
UMLS CUI [1,1]
C3846158
Subject ID
Description

SUBJECT_ID

Type de données

string

Alias
UMLS CUI [1,1]
C2348585
Case control status of the subject for Drug-Induced Liver Injury (DILI)
Description

AFFECTION_STATUS

Type de données

text

Alias
UMLS CUI [1,1]
C3274646
UMLS CUI [1,2]
C0860207
Patient of European ancestry based on genotype
Description

EUROPEAN

Type de données

text

Alias
UMLS CUI [1,1]
C1257905
UMLS CUI [1,2]
C0017431
Considered true DILI after adjudication
Description

TRUE_DILI

Type de données

string

Alias
UMLS CUI [1,1]
C0860207
Candidate causal drug 1
Description

DRUG1

Type de données

string

Alias
UMLS CUI [1,1]
C4527371
UMLS CUI [1,2]
C0013227
Causality score for drug 1
Description

CAUSALITY_DRUG1

Type de données

string

Alias
UMLS CUI [1,1]
C4684583
UMLS CUI [1,2]
C0449820
Candidate causal drug 2
Description

DRUG2

Type de données

string

Alias
UMLS CUI [1,2]
C0013227
UMLS CUI [1,1]
C4527371
Causality score for drug 2
Description

CAUSALITY_DRUG2

Type de données

string

Alias
UMLS CUI [1,1]
C4684583
UMLS CUI [1,2]
C0449820
Candidate causal drug 3
Description

DRUG3

Type de données

string

Alias
UMLS CUI [1,2]
C0013227
UMLS CUI [1,1]
C4527371
Causality score for drug 3
Description

CAUSALITY_DRUG3

Type de données

string

Alias
UMLS CUI [1,1]
C4684583
UMLS CUI [1,2]
C0449820
Gender
Description

GENDER

Type de données

string

Alias
UMLS CUI [1,1]
C0079399
Race 1
Description

RACE1

Type de données

string

Alias
UMLS CUI [1,1]
C0034510
Race 2
Description

RACE2

Type de données

string

Alias
UMLS CUI [1,1]
C0034510
Race 3
Description

RACE3

Type de données

string

Alias
UMLS CUI [1,1]
C0034510
Ethnicity
Description

ETHNICITY

Type de données

string

Alias
UMLS CUI [1,1]
C0015031
Overall causality score
Description

CAUSALITY

Type de données

string

Alias
UMLS CUI [1,1]
C1561607
UMLS CUI [1,2]
C4684583
UMLS CUI [1,3]
C0449820
Type of liver injury
Description

INJURY_TYPE

Type de données

string

Alias
UMLS CUI [1,1]
C0160390
Age at DILI onset
Description

AGE

Type de données

text

Unités de mesure
  • years
Alias
UMLS CUI [1,1]
C0206132
UMLS CUI [1,2]
C0860207
years
Severity of injury
Description

SEVERITY

Type de données

string

Alias
UMLS CUI [1,1]
C4521243
Peak alanine aminotransferase
Description

PEAK_ALT

Type de données

text

Unités de mesure
  • IU/L
Alias
UMLS CUI [1,1]
C0201836
UMLS CUI [1,2]
C0444505
IU/L
Peak serum total bilirubin
Description

PEAK_STB

Type de données

text

Unités de mesure
  • mg/dL
Alias
UMLS CUI [1,1]
C1278039
UMLS CUI [1,2]
C0444505
mg/dL
Peak alkaline phosphatase
Description

PEAK_AKP

Type de données

text

Unités de mesure
  • IU/L
Alias
UMLS CUI [1,1]
C0201850
UMLS CUI [1,2]
C0444505
IU/L
R-value at DILI onset
Description

R_VALUE

Type de données

text

Alias
UMLS CUI [1,1]
C0001899
UMLS CUI [1,2]
C0002059
UMLS CUI [1,3]
C0456603
UMLS CUI [1,4]
C1519815
UMLS CUI [1,5]
C0332162
UMLS CUI [1,6]
C0860207
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Similar models

The subject phenotypes data table includes gender, race (n=3 variables), ethnicity, European ancestry, affection status for drug-induced liver injury (DILI), age at DILI onset, adjudicated DILI diagnosis, candidate drugs (n=3 variables), causality scores of drugs (n=4 variables), injury type, severity, and peak ALT, bilirubin, and AKP measurements, and R-value at DILI onset.

5 Formulaires
Name
Type
Description | Question | Decode (Coded Value)
Type de données
Alias
Item Group
pht003552
C3846158 (UMLS CUI [1,1])
SUBJECT_ID
Item
Subject ID
string
C2348585 (UMLS CUI [1,1])
Item
Case control status of the subject for Drug-Induced Liver Injury (DILI)
text
C3274646 (UMLS CUI [1,1])
C0860207 (UMLS CUI [1,2])
AFFECTION_STATUS
Code List
Case control status of the subject for Drug-Induced Liver Injury (DILI)
CL Item
Case (2)
C3274647 (UMLS CUI [1,1])
CL Item
Suspected DILI ruled as not true DILI (3)
Item
Patient of European ancestry based on genotype
text
C1257905 (UMLS CUI [1,1])
C0017431 (UMLS CUI [1,2])
EUROPEAN
Code List
Patient of European ancestry based on genotype
CL Item
No (0)
CL Item
Yes (1)
TRUE_DILI
Item
Considered true DILI after adjudication
string
C0860207 (UMLS CUI [1,1])
DRUG1
Item
Candidate causal drug 1
string
C4527371 (UMLS CUI [1,1])
C0013227 (UMLS CUI [1,2])
CAUSALITY_DRUG1
Item
Causality score for drug 1
string
C4684583 (UMLS CUI [1,1])
C0449820 (UMLS CUI [1,2])
DRUG2
Item
Candidate causal drug 2
string
C0013227 (UMLS CUI [1,2])
C4527371 (UMLS CUI [1,1] )
CAUSALITY_DRUG2
Item
Causality score for drug 2
string
C4684583 (UMLS CUI [1,1])
C0449820 (UMLS CUI [1,2])
DRUG3
Item
Candidate causal drug 3
string
C0013227 (UMLS CUI [1,2] )
C4527371 (UMLS CUI [1,1] )
CAUSALITY_DRUG3
Item
Causality score for drug 3
string
C4684583 (UMLS CUI [1,1])
C0449820 (UMLS CUI [1,2] )
GENDER
Item
Gender
string
C0079399 (UMLS CUI [1,1])
RACE1
Item
Race 1
string
C0034510 (UMLS CUI [1,1])
RACE2
Item
Race 2
string
C0034510 (UMLS CUI [1,1])
RACE3
Item
Race 3
string
C0034510 (UMLS CUI [1,1])
ETHNICITY
Item
Ethnicity
string
C0015031 (UMLS CUI [1,1])
CAUSALITY
Item
Overall causality score
string
C1561607 (UMLS CUI [1,1])
C4684583 (UMLS CUI [1,2])
C0449820 (UMLS CUI [1,3])
INJURY_TYPE
Item
Type of liver injury
string
C0160390 (UMLS CUI [1,1])
AGE
Item
Age at DILI onset
text
C0206132 (UMLS CUI [1,1])
C0860207 (UMLS CUI [1,2])
SEVERITY
Item
Severity of injury
string
C4521243 (UMLS CUI [1,1])
PEAK_ALT
Item
Peak alanine aminotransferase
text
C0201836 (UMLS CUI [1,1])
C0444505 (UMLS CUI [1,2])
PEAK_STB
Item
Peak serum total bilirubin
text
C1278039 (UMLS CUI [1,1])
C0444505 (UMLS CUI [1,2])
PEAK_AKP
Item
Peak alkaline phosphatase
text
C0201850 (UMLS CUI [1,1])
C0444505 (UMLS CUI [1,2])
R_VALUE
Item
R-value at DILI onset
text
C0001899 (UMLS CUI [1,1])
C0002059 (UMLS CUI [1,2])
C0456603 (UMLS CUI [1,3])
C1519815 (UMLS CUI [1,4])
C0332162 (UMLS CUI [1,5])
C0860207 (UMLS CUI [1,6])
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