English

This subject phenotype table includes subject gender, age that hydroxyurea was initiated, maximum tolerated hydroxyurea dose, baseline fetal hemoglobin level, fetal hemoglobin level at the maximum tolerated dose (MTD) of hydroxyurea, and delta of fetal hemoglobin levels between baseline and MTD.

6 forms  
pht003653
Description

pht003653

Alias
UMLS CUI [1,1]
C3846158
De-identified Subject ID
Description

SUBJID

Data type

text

Alias
UMLS CUI [1,1]
C4684638
UMLS CUI [1,2]
C2348585
Gender of participant
Description

SEX

Data type

text

Alias
UMLS CUI [1,1]
C0079399
Age they initiated the drug, hydroxyurea, in years
Description

START_AGE

Data type

text

Measurement units
  • years
Alias
UMLS CUI [1,1]
C0001779
UMLS CUI [1,2]
C1531783
UMLS CUI [1,3]
C0020402
years
Maximum tolerated daily dose of hydroxyurea in milligrams per kilogram
Description

HU mg/kg

Data type

text

Measurement units
  • mg/kg
Alias
UMLS CUI [1,1]
C0806909
UMLS CUI [1,2]
C2348070
UMLS CUI [1,3]
C0020402
UMLS CUI [1,4]
C0680282
mg/kg
Baseline fetal hemoglobin (HbF) before starting hydroxyurea (%HbF/%HbF+ %HbS)*100
Description

BL F/F+S

Data type

text

Alias
UMLS CUI [1,1]
C1442488
UMLS CUI [1,2]
C0015936
UMLS CUI [1,3]
C0332152
UMLS CUI [1,4]
C0020402
Fetal hemoglobin (HbF) at the maximum hydroxyurea dose
Description

MTD F/F+S

Data type

text

Alias
UMLS CUI [1,1]
C0015936
UMLS CUI [1,2]
C0806909
UMLS CUI [1,3]
C0020402
UMLS CUI [1,4]
C0178602
(MTD F/F+S)-(BL F/F+S), where MTD F/F+S = Fetal hemoglobin (HbF) at the maximum hydroxyurea dose and BL F/F+S = Baseline fetal hemoglobin (HbF) before starting hydroxyurea (%HbF/%HbF+ %HbS)*100.
Description

DELTA HbF

Data type

text

Alias
UMLS CUI [1,1]
C0015936
UMLS CUI [1,2]
C0806909
UMLS CUI [1,3]
C0020402
UMLS CUI [1,4]
C0178602
UMLS CUI [1,5]
C2348589
UMLS CUI [1,6]
C1442488
UMLS CUI [1,7]
C0015936
UMLS CUI [1,8]
C0332152
UMLS CUI [1,9]
C0020402
UMLS CUI [1,10]
C0087111
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Similar models

This subject phenotype table includes subject gender, age that hydroxyurea was initiated, maximum tolerated hydroxyurea dose, baseline fetal hemoglobin level, fetal hemoglobin level at the maximum tolerated dose (MTD) of hydroxyurea, and delta of fetal hemoglobin levels between baseline and MTD.

6 forms
Name
Type
Description | Question | Decode (Coded Value)
Data type
Alias
Item Group
pht003653
C3846158 (UMLS CUI [1,1])
SUBJID
Item
De-identified Subject ID
text
C4684638 (UMLS CUI [1,1])
C2348585 (UMLS CUI [1,2])
Item
Gender of participant
text
C0079399 (UMLS CUI [1,1])
SEX
Code List
Gender of participant
CL Item
Female (F)
C0086287 (UMLS CUI [1,1])
CL Item
Male (M)
C0086582 (UMLS CUI [1,1])
START_AGE
Item
Age they initiated the drug, hydroxyurea, in years
text
C0001779 (UMLS CUI [1,1])
C1531783 (UMLS CUI [1,2])
C0020402 (UMLS CUI [1,3])
HU mg/kg
Item
Maximum tolerated daily dose of hydroxyurea in milligrams per kilogram
text
C0806909 (UMLS CUI [1,1])
C2348070 (UMLS CUI [1,2])
C0020402 (UMLS CUI [1,3])
C0680282 (UMLS CUI [1,4])
BL F/F+S
Item
Baseline fetal hemoglobin (HbF) before starting hydroxyurea (%HbF/%HbF+ %HbS)*100
text
C1442488 (UMLS CUI [1,1])
C0015936 (UMLS CUI [1,2])
C0332152 (UMLS CUI [1,3])
C0020402 (UMLS CUI [1,4])
MTD F/F+S
Item
Fetal hemoglobin (HbF) at the maximum hydroxyurea dose
text
C0015936 (UMLS CUI [1,1])
C0806909 (UMLS CUI [1,2])
C0020402 (UMLS CUI [1,3])
C0178602 (UMLS CUI [1,4])
DELTA HbF
Item
(MTD F/F+S)-(BL F/F+S), where MTD F/F+S = Fetal hemoglobin (HbF) at the maximum hydroxyurea dose and BL F/F+S = Baseline fetal hemoglobin (HbF) before starting hydroxyurea (%HbF/%HbF+ %HbS)*100.
text
C0015936 (UMLS CUI [1,1])
C0806909 (UMLS CUI [1,2])
C0020402 (UMLS CUI [1,3])
C0178602 (UMLS CUI [1,4])
C2348589 (UMLS CUI [1,5])
C1442488 (UMLS CUI [1,6])
C0015936 (UMLS CUI [1,7])
C0332152 (UMLS CUI [1,8])
C0020402 (UMLS CUI [1,9])
C0087111 (UMLS CUI [1,10])
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