Item Group
Inclusion and exclusion criteria
C1512693 (UMLS CUI [1,1])
C0680251 (UMLS CUI [1,2])
Elig.phs000600.v1.p1.1
Item
Surgically resected tumors or biopsies were freshly frozen in nitrogen and stored at minus 80<sup>0</sup>C. Genomic DNA and RNA were extracted from tumors found to have > 40-50% malignant epithelial component based on assessment of hematoxylin stained frozen sections. The Norwegian sample set was enriched for stage IB surgically resectable, grade III tumors. Hematoxylin-eosin slides were reviewed by a pathologist for determination of diagnosis and histological subtype and tumor purity. DNA was also extracted from peripheral blood as corresponding normal. DNA quality was assessed by Affymetrix SNP 6.0 arrays and SNP comparison was used to confirm that a sequenced tumor-normal pair could be attributed to the same individual and that no significant contamination by foreign DNA was present.
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C3846158 (UMLS CUI [1,1])