English

The dataset provides information about disease duration, presence of APOE alleles, time interval between death and tissue harvest, location and extend of plaque and tangle formation, degree of Substantia Nigra depigmentation and status of Lewy body formation observed, Braak/NIA-Reagan scores and general sociodemographic information.

5 forms  
pht003864
Description

pht003864

Alias
UMLS CUI [1,1]
C3846158
De-identified Subject ID
Description

SUBJECT_ID

Data type

string

Alias
UMLS CUI [1,1]
C4684638
UMLS CUI [1,2]
C2348585
Gender of participant
Description

sex

Data type

text

Alias
UMLS CUI [1,1]
C0079399
ApoE allele Gene ID 348
Description

ApoE_status

Data type

text

Alias
UMLS CUI [1,1]
C0003595
UMLS CUI [1,2]
C0002085
UMLS CUI [1,3]
C1706509
Subject's age
Description

age

Data type

text

Measurement units
  • Years
Alias
UMLS CUI [1,1]
C0001779
Years
Length of time with disease
Description

DiseaseDuration

Data type

text

Measurement units
  • Years
Alias
UMLS CUI [1,1]
C0449238
UMLS CUI [1,2]
C0012634
Years
Time between death and autopsy
Description

PostMortemInterval

Data type

text

Measurement units
  • Hours
Alias
UMLS CUI [1,1]
C0449238
UMLS CUI [1,2]
C1148348
UMLS CUI [1,3]
C0004398
Hours
Plaque Frontal lobe
Description

PlaqueF

Data type

text

Alias
UMLS CUI [1,1]
C0016733
UMLS CUI [1,2]
C0332461
Plaque Temporal lobe
Description

PlaqueT

Data type

text

Alias
UMLS CUI [1,1]
C0039485
UMLS CUI [1,2]
C0332461
Plaque Parietal
Description

PlaqueP

Data type

text

Alias
UMLS CUI [1,1]
C0332461
UMLS CUI [1,2]
C0030560
Plaque Hippocampal
Description

PlaqueH

Data type

text

Alias
UMLS CUI [1,1]
C0332461
UMLS CUI [1,2]
C0019564
Plaque Entorhinal
Description

PlaqueE

Data type

text

Alias
UMLS CUI [1,1]
C0332461
UMLS CUI [1,2]
C0175196
PlaqueTotal
Description

PlaqueTotal

Data type

float

Alias
UMLS CUI [1,1]
C0332461
UMLS CUI [1,2]
C0439810
Plaque density
Description

PlaqueDensity

Data type

string

Alias
UMLS CUI [1,1]
C0332461
UMLS CUI [1,2]
C0178587
Tangle Frontal
Description

TangleF

Data type

text

Alias
UMLS CUI [1,1]
C0016733
UMLS CUI [1,2]
C3543859
Tangle Temporal
Description

TangleT

Data type

text

Alias
UMLS CUI [1,1]
C3543859
UMLS CUI [1,2]
C0039485
Tangle Parietal
Description

TangleP

Data type

text

Alias
UMLS CUI [1,1]
C3543859
UMLS CUI [1,2]
C0030560
Tangle Hippocampal
Description

TangleH

Data type

text

Alias
UMLS CUI [1,1]
C3543859
UMLS CUI [1,2]
C0019564
Tangle Entorhinal
Description

TangleE

Data type

text

Alias
UMLS CUI [1,1]
C0175196
UMLS CUI [1,2]
C3543859
TangleTotal
Description

TangleTotal

Data type

float

Alias
UMLS CUI [1,1]
C3543859
UMLS CUI [1,2]
C0439810
Braak score
Description

BraakScore

Data type

text

Alias
UMLS CUI [1,1]
C0348026
UMLS CUI [1,2]
C0449820
UMLS CUI [1,3]
C3846158
NIA - Reagan score
Description

NIA_ReaganScore

Data type

text

Alias
UMLS CUI [1,1]
C0348026
UMLS CUI [1,2]
C0449820
UMLS CUI [1,3]
C3846158
Lewy Body Stage
Description

LewyBody_Stage

Data type

string

Alias
UMLS CUI [1,1]
C0085200
UMLS CUI [1,2]
C1306673
SN - depigmentation
Description

sn_depigmentation

Data type

string

Alias
UMLS CUI [1,1]
C0038590
UMLS CUI [1,2]
C0031911
UMLS CUI [1,3]
C1517945
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The dataset provides information about disease duration, presence of APOE alleles, time interval between death and tissue harvest, location and extend of plaque and tangle formation, degree of Substantia Nigra depigmentation and status of Lewy body formation observed, Braak/NIA-Reagan scores and general sociodemographic information.

5 forms
Name
Type
Description | Question | Decode (Coded Value)
Data type
Alias
Item Group
pht003864
C3846158 (UMLS CUI [1,1])
SUBJECT_ID
Item
De-identified Subject ID
string
C4684638 (UMLS CUI [1,1])
C2348585 (UMLS CUI [1,2])
Item
Gender of participant
text
C0079399 (UMLS CUI [1,1])
sex
Code List
Gender of participant
CL Item
Male (1)
C0086582 (UMLS CUI [1,1])
CL Item
Female (2)
C0086287 (UMLS CUI [1,1])
Item
ApoE allele Gene ID 348
text
C0003595 (UMLS CUI [1,1])
C0002085 (UMLS CUI [1,2])
C1706509 (UMLS CUI [1,3])
ApoE_status
Code List
ApoE allele Gene ID 348
CL Item
ApoE 2 allele present (2)
CL Item
ApoE 3 allele present (3)
CL Item
ApoE4 allele present (4)
CL Item
Both ApoE alleles present (2;2)
CL Item
Both ApoE alleles present (2;3)
CL Item
Both ApoE alleles present (2;4)
CL Item
Both ApoE alleles present (3;3)
CL Item
Both ApoE alleles present (3;4)
CL Item
Both ApoE alleles present (4;4)
age
Item
Subject's age
text
C0001779 (UMLS CUI [1,1])
DiseaseDuration
Item
Length of time with disease
text
C0449238 (UMLS CUI [1,1])
C0012634 (UMLS CUI [1,2])
PostMortemInterval
Item
Time between death and autopsy
text
C0449238 (UMLS CUI [1,1])
C1148348 (UMLS CUI [1,2])
C0004398 (UMLS CUI [1,3])
PlaqueF
Item
Plaque Frontal lobe
text
C0016733 (UMLS CUI [1,1])
C0332461 (UMLS CUI [1,2])
PlaqueT
Item
Plaque Temporal lobe
text
C0039485 (UMLS CUI [1,1])
C0332461 (UMLS CUI [1,2])
PlaqueP
Item
Plaque Parietal
text
C0332461 (UMLS CUI [1,1])
C0030560 (UMLS CUI [1,2])
PlaqueH
Item
Plaque Hippocampal
text
C0332461 (UMLS CUI [1,1])
C0019564 (UMLS CUI [1,2])
PlaqueE
Item
Plaque Entorhinal
text
C0332461 (UMLS CUI [1,1])
C0175196 (UMLS CUI [1,2])
PlaqueTotal
Item
PlaqueTotal
float
C0332461 (UMLS CUI [1,1])
C0439810 (UMLS CUI [1,2])
PlaqueDensity
Item
Plaque density
string
C0332461 (UMLS CUI [1,1])
C0178587 (UMLS CUI [1,2])
TangleF
Item
Tangle Frontal
text
C0016733 (UMLS CUI [1,1])
C3543859 (UMLS CUI [1,2])
TangleT
Item
Tangle Temporal
text
C3543859 (UMLS CUI [1,1])
C0039485 (UMLS CUI [1,2])
TangleP
Item
Tangle Parietal
text
C3543859 (UMLS CUI [1,1])
C0030560 (UMLS CUI [1,2])
TangleH
Item
Tangle Hippocampal
text
C3543859 (UMLS CUI [1,1])
C0019564 (UMLS CUI [1,2])
TangleE
Item
Tangle Entorhinal
text
C0175196 (UMLS CUI [1,1])
C3543859 (UMLS CUI [1,2])
TangleTotal
Item
TangleTotal
float
C3543859 (UMLS CUI [1,1])
C0439810 (UMLS CUI [1,2])
Item
Braak score
text
C0348026 (UMLS CUI [1,1])
C0449820 (UMLS CUI [1,2])
C3846158 (UMLS CUI [1,3])
BraakScore
Code List
Braak score
CL Item
Transentorhinal (I) (I)
CL Item
Transentorhinal (II) (II)
CL Item
Limbic regions (III) (III)
CL Item
Limbic regions (IV) (IV)
CL Item
Neocortical (V) (V)
CL Item
Neocortical (VI) (VI)
Item
NIA - Reagan score
text
C0348026 (UMLS CUI [1,1])
C0449820 (UMLS CUI [1,2])
C3846158 (UMLS CUI [1,3])
NIA_ReaganScore
Code List
NIA - Reagan score
CL Item
AD criteria not met (criteria not met)
CL Item
High likelihood (high)
CL Item
Intermediate likelihood (intermediate)
CL Item
Low likelihood (low)
CL Item
Not Alzheimer's disease (not AD)
LewyBody_Stage
Item
Lewy Body Stage
string
C0085200 (UMLS CUI [1,1])
C1306673 (UMLS CUI [1,2])
sn_depigmentation
Item
SN - depigmentation
string
C0038590 (UMLS CUI [1,1])
C0031911 (UMLS CUI [1,2])
C1517945 (UMLS CUI [1,3])
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