Engelsk

Subject ID, protocol used for subject treatment, treatment arm, infusion of methotrexate, average methotrexate clearance, gender, and genetically determined race of participants with acute lymphoblastic leukemia and involved in the "Methotrexate Clearance GWAS in Acute Lymphoblastic Leukemia (ALL) Patients" project.

5 Formulär  
pht003536
Beskrivning

pht003536

Alias
UMLS CUI [1,1]
C3846158
De-identified subject identifier
Beskrivning

SUBJECT ID

Datatyp

string

Alias
UMLS CUI [1,1]
C4684638
UMLS CUI [1,2]
C2348585
Children's Oncology Group P9904 and P9905 protocols. See Ramsey LB, et. Al. Blool 121(6):898-904, 2013 (PMID:23233662) for details.
Beskrivning

Protocol

Datatyp

string

Alias
UMLS CUI [1,1]
C1516477
UMLS CUI [1,2]
C2348563
Treatment arms in COG P9904/P9905 protocols.
Beskrivning

Treatment arm

Datatyp

string

Alias
UMLS CUI [1,1]
C1522541
Methotrexate 4-hour infusion of a 2g/m2 dose or 24 hour infusion of a 1g/m2 dose
Beskrivning

infusion

Datatyp

string

Alias
UMLS CUI [1,1]
C0025677
UMLS CUI [1,2]
C0574032
UMLS CUI [1,3]
C0449238
UMLS CUI [1,4]
C1442092
Methotrexate clearance averaged over multiple courses for each patient
Beskrivning

average methotrexate clearance

Datatyp

float

Måttenheter
  • mL/min/m2
Alias
UMLS CUI [1,1]
C0025677
UMLS CUI [1,2]
C0449297
UMLS CUI [1,3]
C1510992
mL/min/m2
Methotrexate clearance adjusted for protocol, treatment arm, infusion, gender, genetically determined race; mean clearance among patient population was normalized to zero.
Beskrivning

Adjusted methotrexate clearance

Datatyp

float

Måttenheter
  • mL/min/m2
Alias
UMLS CUI [1,1]
C0025677
UMLS CUI [1,2]
C0449297
UMLS CUI [1,3]
C1522541
UMLS CUI [1,4]
C0574032
UMLS CUI [1,5]
C0079399
UMLS CUI [1,6]
C0034510
UMLS CUI [1,7]
C1510992
UMLS CUI [1,8]
C0038136
mL/min/m2
Male or female
Beskrivning

gender

Datatyp

string

Alias
UMLS CUI [1,1]
C0079399
UMLS CUI [1,2]
C0086582
UMLS CUI [1,3]
C0086287
Race genetcially determined using STRUCTURE with genome-wide mapping array
Beskrivning

genetically determined Race

Datatyp

string

Alias
UMLS CUI [1,1]
C0034510
UMLS CUI [1,2]
C1148554
UMLS CUI [1,3]
C0079435
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Similar models

Subject ID, protocol used for subject treatment, treatment arm, infusion of methotrexate, average methotrexate clearance, gender, and genetically determined race of participants with acute lymphoblastic leukemia and involved in the "Methotrexate Clearance GWAS in Acute Lymphoblastic Leukemia (ALL) Patients" project.

5 Formulär
Name
Typ
Description | Question | Decode (Coded Value)
Datatyp
Alias
Item Group
pht003536
C3846158 (UMLS CUI [1,1])
SUBJECT ID
Item
De-identified subject identifier
string
C4684638 (UMLS CUI [1,1])
C2348585 (UMLS CUI [1,2])
Protocol
Item
Children's Oncology Group P9904 and P9905 protocols. See Ramsey LB, et. Al. Blool 121(6):898-904, 2013 (PMID:23233662) for details.
string
C1516477 (UMLS CUI [1,1])
C2348563 (UMLS CUI [1,2])
Treatment arm
Item
Treatment arms in COG P9904/P9905 protocols.
string
C1522541 (UMLS CUI [1,1])
infusion
Item
Methotrexate 4-hour infusion of a 2g/m2 dose or 24 hour infusion of a 1g/m2 dose
string
C0025677 (UMLS CUI [1,1])
C0574032 (UMLS CUI [1,2])
C0449238 (UMLS CUI [1,3])
C1442092 (UMLS CUI [1,4])
average methotrexate clearance
Item
Methotrexate clearance averaged over multiple courses for each patient
float
C0025677 (UMLS CUI [1,1])
C0449297 (UMLS CUI [1,2])
C1510992 (UMLS CUI [1,3])
Adjusted methotrexate clearance
Item
Methotrexate clearance adjusted for protocol, treatment arm, infusion, gender, genetically determined race; mean clearance among patient population was normalized to zero.
float
C0025677 (UMLS CUI [1,1])
C0449297 (UMLS CUI [1,2])
C1522541 (UMLS CUI [1,3])
C0574032 (UMLS CUI [1,4])
C0079399 (UMLS CUI [1,5])
C0034510 (UMLS CUI [1,6])
C1510992 (UMLS CUI [1,7])
C0038136 (UMLS CUI [1,8])
gender
Item
Male or female
string
C0079399 (UMLS CUI [1,1])
C0086582 (UMLS CUI [1,2])
C0086287 (UMLS CUI [1,3])
genetically determined Race
Item
Race genetcially determined using STRUCTURE with genome-wide mapping array
string
C0034510 (UMLS CUI [1,1])
C1148554 (UMLS CUI [1,2])
C0079435 (UMLS CUI [1,3])
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