5.0 ELIGIBILITY
Item
*5.0 ELIGIBILITY*
boolean
C1516637 (UMLS CUI [1,1])
5.1 Patient population
Item
*5.1 Patient population*
boolean
C1516637 (UMLS CUI [1,1])
C2361270 (UMLS CUI [1,2])
This protocol is designed to collect biospecimens with annotated clinical data from patients with advanced or refractory cancer.
Item
This protocol is designed to collect biospecimens with annotated clinical data from patients with advanced or refractory cancer.
boolean
C1516637 (UMLS CUI [1,1])
C0200345 (UMLS CUI [1,2])
C1516606 (UMLS CUI [1,3])
C1552657 (UMLS CUI [1,4])
C0877373 (UMLS CUI [1,5])
C0677936 (UMLS CUI [1,6])
Elig.phs000602.v2.p1.4
Item
*5.2 Inclusion Criteria: (Must satisfy all criteria and either #3 or #4)*
boolean
C1516637 (UMLS CUI [1,1])
C1512693 (UMLS CUI [1,2])
A histologically or cytologically confirmed diagnosis of cancer.
Item
A histologically or cytologically confirmed diagnosis of cancer.
boolean
C1516637 (UMLS CUI [1,1])
C1512693 (UMLS CUI [1,2])
C0920688 (UMLS CUI [1,3])
C0679557 (UMLS CUI [1,4])
C1298647 (UMLS CUI [1,5])
Patients with any advanced or refractory malignancy.
Item
Patients with any advanced or refractory malignancy.
boolean
C1516637 (UMLS CUI [1,1])
C1512693 (UMLS CUI [1,2])
C0877373 (UMLS CUI [1,3])
C0677936 (UMLS CUI [1,4])
Patients are undergoing standard of care surgeries or procedures where specimens will be first used for routine pathologic assessment and only then will leftover tissue be used for research purposes.
Item
Patients are undergoing standard of care surgeries or procedures where specimens will be first used for routine pathologic assessment and only then will leftover tissue be used for research purposes. **OR**
boolean
C1516637 (UMLS CUI [1,1])
C1512693 (UMLS CUI [1,2])
C2936643 (UMLS CUI [1,3])
C0543467 (UMLS CUI [1,4])
C1516637 (UMLS CUI [2,1])
C0205225 (UMLS CUI [2,2])
C1524063 (UMLS CUI [2,3])
C0370003 (UMLS CUI [2,4])
C4086729 (UMLS CUI [2,5])
C1524062 (UMLS CUI [2,6])
C0040300 (UMLS CUI [2,7])
C0242481 (UMLS CUI [2,8])
Patients must have tumor suitable for biopsy (as assessed by trained specialists in interventional radiology) and patients are medically fit to undergo a tissue biopsy or surgical procedure to get tumor tissue *OR* if patients do not have a tumor suitable for biopsy but have another tissue available for molecular evaluation.
Item
Patients must have tumor suitable for biopsy (as assessed by trained specialists in interventional radiology) and patients are medically fit to undergo a tissue biopsy or surgical procedure to get tumor tissue *OR* if patients do not have a tumor suitable for biopsy but have another tissue available for molecular evaluation.
boolean
C1516637 (UMLS CUI [1,1])
C1512693 (UMLS CUI [1,2])
C0006826 (UMLS CUI [1,3])
C0005558 (UMLS CUI [1,4])
C0332149 (UMLS CUI [1,5])
C1516048 (UMLS CUI [1,6])
C0034602 (UMLS CUI [1,7])
C2348234 (UMLS CUI [1,8])
C4708589 (UMLS CUI [1,9])
C0185275 (UMLS CUI [1,10])
C1516637 (UMLS CUI [2,1])
C1512693 (UMLS CUI [2,2])
C1298908 (UMLS CUI [2,3])
C4708589 (UMLS CUI [2,4])
C0185275 (UMLS CUI [2,5])
C0040300 (UMLS CUI [2,6])
C2985722 (UMLS CUI [2,7])
C2121080 (UMLS CUI [2,8])
Older than or equal to 18 years of age.
Item
Older than or equal to 18 years of age.
boolean
C1516637 (UMLS CUI [1,1])
C1512693 (UMLS CUI [1,2])
C0001779 (UMLS CUI [1,3])
Procedure-specific signed informed consent prior to initiation of any study-related procedures.
Item
Procedure-specific signed informed consent prior to initiation of any study-related procedures.
boolean
C1516637 (UMLS CUI [1,1])
C0021430 (UMLS CUI [1,2])
C1512693 (UMLS CUI [1,3])
C1561610 (UMLS CUI [1,4])
C5421123 (UMLS CUI [1,5])
Women and minorities are included in this protocol.
Item
Women and minorities are included in this protocol.
boolean
C1516637 (UMLS CUI [1,1])
C1512693 (UMLS CUI [1,2])
C0026192 (UMLS CUI [1,3])
C0043210 (UMLS CUI [1,4])
Patients with multiple malignancies remain eligible.
Item
Patients with multiple malignancies remain eligible.
boolean
C1516637 (UMLS CUI [1,1])
C0006826 (UMLS CUI [1,2])
C1302261 (UMLS CUI [1,3])
C1512693 (UMLS CUI [1,4])
Patients with an inherited cancer syndrome or a medical history suggestive of an inherited cancer syndrome remain eligible.
Item
Patients with an inherited cancer syndrome or a medical history suggestive of an inherited cancer syndrome remain eligible.
boolean
C1516637 (UMLS CUI [1,1])
C1302261 (UMLS CUI [1,2])
C0027672 (UMLS CUI [1,3])
5.3 Exclusion Criteria:
Item
*5.3 Exclusion Criteria:*
boolean
C0680251 (UMLS CUI [1,1])
It is the enrolling study physician's discretion to decide if a patient is not fit enough to undergo tissue biopsy.
Item
It is the enrolling study physician's discretion to decide if a patient is not fit enough to undergo tissue biopsy.
boolean
C0680251 (UMLS CUI [1,1])
C0008961 (UMLS CUI [1,2])
C0022423 (UMLS CUI [1,3])
C0750557 (UMLS CUI [1,4])
C2586066 (UMLS CUI [1,5])
Patients who are incarcerated are not eligible to participate.
Item
Patients who are incarcerated are not eligible to participate.
boolean
C0680251 (UMLS CUI [1,1])
C0030705 (UMLS CUI [1,2])
C0392751 (UMLS CUI [1,3])
C1555471 (UMLS CUI [1,4])
Women who are pregnant.
Item
Women who are pregnant.
boolean
C0680251 (UMLS CUI [1,1])
C0033011 (UMLS CUI [1,2])
5.4 Women of childbearing age.
Item
*5.4 Women of childbearing age.*
boolean
C0680251 (UMLS CUI [1,1])
C3831118 (UMLS CUI [1,2])
C0043210 (UMLS CUI [1,3])
For women of childbearing age, there are no screening requirements. We note that most patients entering this study are seeking eligibility for therapy or other clinical trial, in which case they are generally asked to avoiding becoming pregnant and even exercise some form of contraception by their medical oncologist. For women of childbearing age, their referring medical oncologist will discuss necessity or role for appropriate contraception. This is not part of the study activity, nor is it required for participation.
Item
For women of childbearing age, there are no screening requirements. We note that most patients entering this study are seeking eligibility for therapy or other clinical trial, in which case they are generally asked to avoiding becoming pregnant and even exercise some form of contraception by their medical oncologist. For women of childbearing age, their referring medical oncologist will discuss necessity or role for appropriate contraception. This is not part of the study activity, nor is it required for participation.
boolean
C0680251 (UMLS CUI [1,1])
C0043210 (UMLS CUI [1,2])
C3831118 (UMLS CUI [1,3])
C0220908 (UMLS CUI [1,4])
C1514873 (UMLS CUI [1,5])
C1298908 (UMLS CUI [1,6])