ESP_COHORT
Item
Cohort name
string
C0599755 (UMLS CUI [1,1])
C0027365 (UMLS CUI [1,2])
SUBJID
Item
De-identified subject ID
string
C2348585 (UMLS CUI [1,1])
C4684638 (UMLS CUI [1,2])
ESP_PHENOTYPE
Item
Values: EOMI_Case (Early MI case); EOMI_Control (Early MI control; LDL_High; LDL_Low
string
C3274648 (UMLS CUI [1,1])
C4014367 (UMLS CUI [1,2])
C3274647 (UMLS CUI [2,1])
C4014367 (UMLS CUI [2,2])
SAMPLE_QC_INFO
Item
Information from quality control analysis
string
C0034378 (UMLS CUI [1,1])
C0936012 (UMLS CUI [1,2])
DUP_RELATED_INFO
Item
Information about known duplicates and related
string
C3846158 (UMLS CUI [1,1])
ESP_RACE
Item
Values: European American; African American
string
C3853635 (UMLS CUI [1,1])
C0683983 (UMLS CUI [1,2])
C3853635 (UMLS CUI [2,1])
C0085756 (UMLS CUI [2,2])
ESP_SEX
Item
Values: Male; Female
string
C0079399 (UMLS CUI [1,1])
C0086582 (UMLS CUI [1,2])
C0079399 (UMLS CUI [2,1])
C0086287 (UMLS CUI [2,2])
ESP_STUDY_SITE
Item
Clinic or field center within cohort
string
C3846158 (UMLS CUI [1,1])
ESP_AGE_BASELINE
Item
Age in years at baseline
text
C0001779 (UMLS CUI [1,1])
C1442488 (UMLS CUI [1,2])
Item
MI status at baseline [0=No, 1=Yes]
text
C0027051 (UMLS CUI [1,1])
C1442488 (UMLS CUI [1,2])
Code List
MI status at baseline [0=No, 1=Yes]
Item
0/1 - to indicate that an MI occurred during study follow up. 0 - if no MI during study follow up. 1 - if an adjudicated MI occurred during study follow up (even if baseline MI status was 1).
text
C0027051 (UMLS CUI [1,1])
C1522577 (UMLS CUI [1,2])
Code List
0/1 - to indicate that an MI occurred during study follow up. 0 - if no MI during study follow up. 1 - if an adjudicated MI occurred during study follow up (even if baseline MI status was 1).
ESP_MI_TTE_OR_CENSOR
Item
Time to event variable for MI. Time (in days) from start of study to MI for event that occurred during study follow up; and follow up time for those that did not have an MI during study follow up.
text
C0027051 (UMLS CUI [1,1])
C1522577 (UMLS CUI [1,2])
C0027051 (UMLS CUI [2,1])
C1518422 (UMLS CUI [2,2])
C1522577 (UMLS CUI [2,3])
C0040223 (UMLS CUI [2,4])
ESP_FRS_CHDPROB_BASELINE
Item
Framingham Risk Score predicted probably calculated at baseline (was not calculated for those with baseline history of MI).
text
C3176199 (UMLS CUI [1,1])
C1442488 (UMLS CUI [1,2])
ESP_BMI_BASELINE
Item
Baseline BMI in kg/m2
text
C1305855 (UMLS CUI [1,1])
C1442488 (UMLS CUI [1,2])
Item
Type 2 diabetes status at baseline [0=No, 1=Yes]
text
C4014362 (UMLS CUI [1,1])
C1442488 (UMLS CUI [1,2])
Code List
Type 2 diabetes status at baseline [0=No, 1=Yes]
ESP_WEIGHT_BASELINE
Item
Weight in kg. at baseline
text
C0005910 (UMLS CUI [1,1])
C1442488 (UMLS CUI [1,2])
ESP_WAIST_BASELINE
Item
Waist in cm at baseline
text
C0455829 (UMLS CUI [1,1])
C1442488 (UMLS CUI [1,2])
ESP_WHR_BASELINE
Item
Waist to hip ratio at baseline
text
C0205682 (UMLS CUI [1,1])
C1442488 (UMLS CUI [1,2])
ESP_HEIGHT_BASELINE
Item
Standing height in cm at baseline
text
C0005890 (UMLS CUI [1,1])
C0231472 (UMLS CUI [1,2])
C1442488 (UMLS CUI [1,3])
ESP_LDL_BASELINE
Item
Baseline calculated LDL in mg/dL (missing where trigs>400)
text
C2209033 (UMLS CUI [1,1])
C1442488 (UMLS CUI [1,2])
ESP_HDL_BASELINE
Item
HDL level in mg/dL at baseline
text
C0428472 (UMLS CUI [1,1])
C1442488 (UMLS CUI [1,2])
ESP_TRIGS_BASELINE
Item
Triglycerides at baseline in mg/dL
text
C0202236 (UMLS CUI [1,1])
C1442488 (UMLS CUI [1,2])
ESP_TOTCHOL_BASELINE
Item
Total cholesterol at baseline in mg/dL
text
C1445957 (UMLS CUI [1,1])
C1442488 (UMLS CUI [1,2])
Item
Any lipid lowering medication (statin or other) at baseline
text
C0086440 (UMLS CUI [1,1])
C1442488 (UMLS CUI [1,2])
Code List
Any lipid lowering medication (statin or other) at baseline
ESP_SBP_BASELINE
Item
Systolic blood pressure at baseline (avg. of 2 measurements), in mm Hg
text
C0871470 (UMLS CUI [1,1])
C1442488 (UMLS CUI [1,2])
ESP_DBP_BASELINE
Item
Diastolic blood pressure at baseline (avg. of 2 measurements), in mm Hg
text
C0428883 (UMLS CUI [1,1])
C1442488 (UMLS CUI [1,2])
Item
Physician diagnosed hypertension status at baseline [0=No, 1=Yes]
text
C0020538 (UMLS CUI [1,1])
C1442488 (UMLS CUI [1,2])
Code List
Physician diagnosed hypertension status at baseline [0=No, 1=Yes]
Item
Hypertension medication status (any) at baseline [0=No, 1=Yes]
text
C0003364 (UMLS CUI [1,1])
C1442488 (UMLS CUI [1,2])
Code List
Hypertension medication status (any) at baseline [0=No, 1=Yes]
Item
Stroke status at baseline [0=No, 1=Yes]
text
C0038454 (UMLS CUI [1,1])
C1442488 (UMLS CUI [1,2])
Code List
Stroke status at baseline [0=No, 1=Yes]
Item
0/1 - to indicate that a stroke occurred during study follow up. 0 - if no stroke during study follow up. 1 - if an adjudicated stroke occurred during study follow up (even if baseline stroke status was 1).
text
C0038454 (UMLS CUI [1,1])
C1522577 (UMLS CUI [1,2])
Code List
0/1 - to indicate that a stroke occurred during study follow up. 0 - if no stroke during study follow up. 1 - if an adjudicated stroke occurred during study follow up (even if baseline stroke status was 1).
ESP_STROKE_TTE_OR_CENSOR
Item
Time to event variable for stroke. Time (in days) from start of study to stroke for event that occurred during study follow up; and follow up time for those that did not have an stroke during study follow up.
text
C0038454 (UMLS CUI [1,1])
C1522577 (UMLS CUI [1,2])
C0038454 (UMLS CUI [2,1])
C1518422 (UMLS CUI [2,2])
C1522577 (UMLS CUI [2,3])
C0040223 (UMLS CUI [2,4])
ESP_INC_STROKE_SUBTYPE
Item
Incident stroke subtype (Lacune or LVAth). Subtype is available only on a subset of samples, so will be missing for some with non-missing age at incident stroke.
text
C0038454 (UMLS CUI [1,1])
C0449560 (UMLS CUI [1,2])
Item
Family history (first degree relatives) of stroke at baseline [0=No, 1=Yes]
text
C1261367 (UMLS CUI [1,1])
C1442488 (UMLS CUI [1,2])
Code List
Family history (first degree relatives) of stroke at baseline [0=No, 1=Yes]
Item
Current smoking status at baseline [0=No, 1=Yes]
text
C1519386 (UMLS CUI [1,1])
C1442488 (UMLS CUI [1,2])
Code List
Current smoking status at baseline [0=No, 1=Yes]
Item
Former smoking status at baseline [0=No, 1=Yes]
text
C0337671 (UMLS CUI [1,1])
C1442488 (UMLS CUI [1,2])
Code List
Former smoking status at baseline [0=No, 1=Yes]
ESP_AGE_AT_MENARCHE
Item
Age at menarche
text
C1314691 (UMLS CUI [1,1])
Item
Age categories for menarche
text
C1314691 (UMLS CUI [1,1])
C0683312 (UMLS CUI [1,2])
Code List
Age categories for menarche
Item
Atrial fibrillation at baseline [0=No, 1=Yes]
text
C0004238 (UMLS CUI [1,1])
C1442488 (UMLS CUI [1,2])
Code List
Atrial fibrillation at baseline [0=No, 1=Yes]
Item
0/1 - to indicate that an atrial fibrillation occurred during study follow up. 0 - if no atrial fibrillation during study follow up. 1 - if an adjudicated atrial fibrillation occurred during study follow up.
text
C0004238 (UMLS CUI [1,1])
C1522577 (UMLS CUI [1,2])
Code List
0/1 - to indicate that an atrial fibrillation occurred during study follow up. 0 - if no atrial fibrillation during study follow up. 1 - if an adjudicated atrial fibrillation occurred during study follow up.
ESP_AFIB_TTE_OR_CENSOR
Item
Time to event variable for atrial fibrillation (afib). Time (in days) from start of study to afib for event that occurred during study follow up; and follow up time for those that did not have an atrial fibrillation during study follow up.
text
C0004238 (UMLS CUI [1,1])
C1522577 (UMLS CUI [1,2])
C0004238 (UMLS CUI [2,1])
C1518422 (UMLS CUI [2,2])
C1522577 (UMLS CUI [2,3])
C0040223 (UMLS CUI [2,4])
ESP_FASTINSULIN_BASELINE
Item
Blood fasting insulin at baseline in uU/mL. (Note that there are some extreme outliers)
text
C0853230 (UMLS CUI [1,1])
C0015663 (UMLS CUI [1,2])
C1442488 (UMLS CUI [1,3])
ESP_FASTGLUCOSE_BASELINE
Item
Blood fasting glucose at baseline in mg/dL
text
C0428568 (UMLS CUI [1,1])
C1442488 (UMLS CUI [1,2])
ESP_FIBRINOGEN
Item
Fibrinogen level in mg/dL at first designated visit (may not be baseline)
text
C1318051 (UMLS CUI [1,1])
C4019187 (UMLS CUI [1,2])
ESP_AGE_AT_FIBRINOGEN
Item
Age in years at Fibrinogen measurement
text
C0337428 (UMLS CUI [1,1])
C0001779 (UMLS CUI [1,2])
ESP_FACTORVII
Item
Factor VII level in % at designated visit (may not be baseline)
text
C0427593 (UMLS CUI [1,1])
C0589121 (UMLS CUI [1,2])
ESP_AGE_AT_FACTORVII
Item
Age in years at Factor VII measurement
text
C2825856 (UMLS CUI [1,1])
C0001779 (UMLS CUI [1,2])
ESP_FACTORVIII
Item
Factor VIII level in % at designated visit (may not be baseline)
text
C0457997 (UMLS CUI [1,1])
C0589121 (UMLS CUI [1,2])
ESP_AGE_AT_FACTORVIII
Item
Age in years at Factor VIII measurement
text
C2825857 (UMLS CUI [1,1])
C0001779 (UMLS CUI [1,2])
ESP_vWF
Item
VWF level in % at designated visit (may not be baseline)
text
C0427585 (UMLS CUI [1,1])
C0589121 (UMLS CUI [1,2])
ESP_AGE_AT_vWF
Item
Age in years at visit of hemostatic factors measurement
text
C0242485 (UMLS CUI [1,1])
C0005515 (UMLS CUI [1,2])
C0019116 (UMLS CUI [1,3])
C0001779 (UMLS CUI [1,4])
ESP_CRP
Item
C-reactive protein level in mg/L at designated visit (may not be baseline)
text
C0428528 (UMLS CUI [1,1])
C0589121 (UMLS CUI [1,2])
ESP_AGE_AT_CRP
Item
Age in years at CRP measurement
text
C0201657 (UMLS CUI [1,1])
C0001779 (UMLS CUI [1,2])
ESP_IL6
Item
IL6 level in pg/mL at designated visit (may not be baseline)
text
C0021760 (UMLS CUI [1,1])
C0589121 (UMLS CUI [1,2])
ESP_AGE_AT_IL6
Item
Age in years at IL6 measurement
text
C0242485 (UMLS CUI [1,1])
C0021760 (UMLS CUI [1,2])
C0001779 (UMLS CUI [1,3])
ESP_ICAM1
Item
ICAM1 level in ng/mL at designated visit (may not be baseline)
text
C4084871 (UMLS CUI [1,1])
C0589121 (UMLS CUI [1,2])
ESP_AGE_AT_ICAM1
Item
Age in years at ICAM1 measurement
text
C4084871 (UMLS CUI [1,1])
C0001779 (UMLS CUI [1,2])
ESP_PSELECTIN
Item
P-selectin level at designated visit (may not be baseline)
text
C3890352 (UMLS CUI [1,1])
C0589121 (UMLS CUI [1,2])
ESP_AGE_AT_PSELECTIN
Item
Age in years at P-selectin measurement
text
C3890352 (UMLS CUI [1,1])
C0001779 (UMLS CUI [1,2])
ESP_WBC
Item
White blood count in x1,000/cubic mm at designated visit (may not be baseline)
text
C1821144 (UMLS CUI [1,1])
C0589121 (UMLS CUI [1,2])
ESP_AGE_AT_WBC
Item
Age in years at WBC measurement
text
C0023508 (UMLS CUI [1,1])
C0001779 (UMLS CUI [1,2])
ESP_HEMOGLOBIN
Item
Hemoglobin at designated visit (may not be baseline) in g/dl
text
C0518015 (UMLS CUI [1,1])
C0589121 (UMLS CUI [1,2])
ESP_AGE_AT_HEMOGLOBIN
Item
Age in years at hemoglobin measurement
text
C0518015 (UMLS CUI [1,1])
C0001779 (UMLS CUI [1,2])
ESP_HEMATOCRIT
Item
Hematocrit at designated visit (may not be baseline) in %
text
C0518014 (UMLS CUI [1,1])
C0589121 (UMLS CUI [1,2])
ESP_AGE_AT_HEMATOCRIT
Item
Age in years at hematocrit measurement
text
C0518014 (UMLS CUI [1,1])
C0242485 (UMLS CUI [1,2])
C0001779 (UMLS CUI [1,3])
ESP_PLATELET_COUNT
Item
Platelet count at designated visit (may not be baseline) in x 1000/cubic mm
text
C0032181 (UMLS CUI [1,1])
C0589121 (UMLS CUI [1,2])
ESP_AGE_AT_PLATELET_COUNT
Item
Age in years at platelet count measurement
text
C0032181 (UMLS CUI [1,1])
C0001779 (UMLS CUI [1,2])
ESP_MEAN_CORPUSCULAR_VOLUME
Item
Mean corpuscular volume in femtoliters at designated visit (may not be baseline)
text
C1948043 (UMLS CUI [1,1])
C0589121 (UMLS CUI [1,2])
ESP_AGE_AT_MCV
Item
Age in years at mean corpuscular volume measurement
text
C1948043 (UMLS CUI [1,1])
C0001779 (UMLS CUI [1,2])
ESP_RED_BLOOD_COUNT
Item
Red blood cell count in million cells per microliter at designated visit (may not be baseline)
text
C0014772 (UMLS CUI [1,1])
C0589121 (UMLS CUI [1,2])
ESP_AGE_AT_RBC
Item
Age in years at red blood cell count measurement
text
C0014772 (UMLS CUI [1,1])
C0001779 (UMLS CUI [1,2])
ESP_NEUTROPHILS
Item
Neutrophils in absolute numbers at designated visit (may not be baseline).
text
C0948762 (UMLS CUI [1,1])
C0589121 (UMLS CUI [1,2])
ESP_MONOCYTES
Item
Monocytes in absolute numbers at designated visit (may not be baseline).
text
C5243958 (UMLS CUI [1,1])
C0589121 (UMLS CUI [1,2])
ESP_LYMPHOCYTES
Item
Lymphocytes in absolute numbers at designated visit (may not be baseline).
text
C3544087 (UMLS CUI [1,1])
C0589121 (UMLS CUI [1,2])
ESP_EOSINOPHILS
Item
Eosinophils in absolute numbers at designated visit (may not be baseline).
text
C0750879 (UMLS CUI [1,1])
C0589121 (UMLS CUI [1,2])
ESP_BASOPHILS
Item
Basophils in absolute numbers at designated visit (may not be baseline)
text
C1883362 (UMLS CUI [1,1])
C0589121 (UMLS CUI [1,2])
ESP_AGE_AT_SECONDARY_BLOOD_COUNT
Item
Age in years at secondary blood count measurements (MCV, RBC, Neutrophils, Monocytes, Lymphocytes, Eosinophils, Basophils)
text
C0009555 (UMLS CUI [1,1])
C0001779 (UMLS CUI [1,2])
Item
Baseline angioplasty status [ 0=No, 1=Yes]
text
C0162577 (UMLS CUI [1,1])
C1442488 (UMLS CUI [1,2])
Code List
Baseline angioplasty status [ 0=No, 1=Yes]
Item
Baseline CABG status [ 0=No, 1=Yes]
text
C0010055 (UMLS CUI [1,1])
C1442488 (UMLS CUI [1,2])
Code List
Baseline CABG status [ 0=No, 1=Yes]
ESP_CAC_AGATSTON_SCORE
Item
Coronary artery calcium Agatston total score
text
C2825178 (UMLS CUI [1,1])
ESP_AGE_AT_CAC
Item
Age in years at CAC Agatston score measurement
text
C3484386 (UMLS CUI [1,1])
C0001779 (UMLS CUI [1,2])
ESP_IMT_MEANMEAN_FARWALL_CCA
Item
Average far wall thickness of the right and left common carotid mean IMT values, using as many views as are available for a given study.
text
C0442071 (UMLS CUI [1,1])
C0444504 (UMLS CUI [1,2])
C0226086 (UMLS CUI [1,3])
C0226087 (UMLS CUI [1,4])
C1960467 (UMLS CUI [1,5])
C0444504 (UMLS CUI [1,6])
ESP_IMT_MEANMEAN_FARWALL_ICA
Item
Average far wall thickness of the right and left internal carotid maximum IMT values, using as many views as are available for a given study.
text
C0444504 (UMLS CUI [1,1])
C0442071 (UMLS CUI [1,2])
C0226157 (UMLS CUI [1,3])
C0226156 (UMLS CUI [1,4])
C1960467 (UMLS CUI [1,5])
C0806909 (UMLS CUI [1,6])
Item
Presence of any plaque, as determined by IMT at designated visit (may not be baseline).
text
C2936350 (UMLS CUI [1,1])
C1960467 (UMLS CUI [1,2])
C0589121 (UMLS CUI [1,3])
Code List
Presence of any plaque, as determined by IMT at designated visit (may not be baseline).
ESP_AGE_AT_IMT
Item
Age in years at IMT measurement
text
C0242485 (UMLS CUI [1,1])
C1960467 (UMLS CUI [1,2])
C0001779 (UMLS CUI [1,3])
ESP_EKG_QRS
Item
QRS interval from EKG at designated visit (may not be baseline)
text
C0429025 (UMLS CUI [1,1])
C0589121 (UMLS CUI [1,2])
ESP_EKG_RR
Item
RR interval from EKG at designated visit (may not be baseline)
text
C0489636 (UMLS CUI [1,1])
C0589121 (UMLS CUI [1,2])
ESP_EKG_QT
Item
QT interval from EKG at designated visit (may not be baseline)
text
C0429028 (UMLS CUI [1,1])
C0589121 (UMLS CUI [1,2])
ESP_EKG_PR
Item
PR interval from EKG at designated visit (may not be baseline)
text
C0429024 (UMLS CUI [1,1])
C0589121 (UMLS CUI [1,2])
ESP_EKG_HR
Item
HR interval from EKG at designated visit (may not be baseline)
text
C3846158 (UMLS CUI [1,1])
ESP_LVH_AT_EKG
Item
Left ventriculat hypertrophy status at baseline [0=No, 1=Yes]
text
C0149721 (UMLS CUI [1,1])
C1442488 (UMLS CUI [1,2])
ESP_AFLUT_AT_EKG
Item
Atrial flutter at EKG
text
C0004239 (UMLS CUI [1,1])
ESP_WPW_AT_EKG
Item
Wolf-Parkinson-White pattern
text
C0043202 (UMLS CUI [1,1])
ESP_AVBLOCK2_AT_EKG
Item
Second degree AV block
text
C0264906 (UMLS CUI [1,1])
ESP_AVBLOCK3_AT_EKG
Item
Third degree AV block
text
C0151517 (UMLS CUI [1,1])
Item
Cornell voltage for EKG measurement, for EKG group.
text
C0428967 (UMLS CUI [1,1])
C0149721 (UMLS CUI [1,2])
Code List
Cornell voltage for EKG measurement, for EKG group.
Item
Pacer at EKG
text
C0030163 (UMLS CUI [1,1])
C0438154 (UMLS CUI [1,2])
Item
Digoxin, for EKG group
text
C0012265 (UMLS CUI [1,1])
Code List
Digoxin, for EKG group
Item
Dihydropyridine calcium channel blockers
text
C2945601 (UMLS CUI [1,1])
Code List
Dihydropyridine calcium channel blockers
Item
Non-dihydropyridine calcium channel blockers, for EKG group
text
C0006684 (UMLS CUI [1,1])
C0332300 (UMLS CUI [1,2])
C2945601 (UMLS CUI [1,3])
Code List
Non-dihydropyridine calcium channel blockers, for EKG group
Item
Any Calcium Channel blocker (only for ARIC - other HeartGO cohorts have this broken down by Dihydro versus Non-Dihydro)
text
C0006684 (UMLS CUI [1,1])
C1552551 (UMLS CUI [1,2])
Code List
Any Calcium Channel blocker (only for ARIC - other HeartGO cohorts have this broken down by Dihydro versus Non-Dihydro)
Item
Betablockers, for EKG group
text
C0001645 (UMLS CUI [1,1])
Code List
Betablockers, for EKG group
ESP_AGE_AT_EKG
Item
Age in years at EKG measurement
text
C1623258 (UMLS CUI [1,1])
C0001779 (UMLS CUI [1,2])
ESP_SERUM_CYSTATINC
Item
Raw cystatin C (mg/L)
text
C1619716 (UMLS CUI [1,1])
ESP_AGE_AT_SERUM_CYSTATINC
Item
Age in years at serum cystatin c measurement
text
C1619716 (UMLS CUI [1,1])
C0001779 (UMLS CUI [1,2])
ESP_URIC_ACID
Item
Uric acid in mg/dL
text
C0202239 (UMLS CUI [1,1])
ESP_AGE_AT_URIC_ACID
Item
Age in years at uric acid measurement
text
C0202239 (UMLS CUI [1,1])
C0001779 (UMLS CUI [1,2])
ESP_URINARY_ALBUMIN
Item
Raw urinary albumin. Note: Users need to confirm units are the same across cohorts
text
C0587185 (UMLS CUI [1,1])
ESP_AGE_AT_URINARY_ALBUMIN
Item
Age in years at urinary albumin measurement
text
C1318429 (UMLS CUI [1,1])
C0001779 (UMLS CUI [1,2])
ESP_URINARY_CREATININE
Item
Raw urinary creatinine in mg/dL
text
C1318439 (UMLS CUI [1,1])
ESP_AGE_AT_URINARY_CREATININE
Item
Age in years at urinary creatinine measurement
text
C1318439 (UMLS CUI [1,1])
C0001779 (UMLS CUI [1,2])
Item
May be MD-reported, self-reported, or abstracted from patients taking allopurinol. Ever had gout through study.
text
C0018099 (UMLS CUI [1,1])
Code List
May be MD-reported, self-reported, or abstracted from patients taking allopurinol. Ever had gout through study.