GENEVA_ID
Item
NHS/HPFS/GEP: Unique GENEVA ID
text
C2348585 (UMLS CUI [1,1])
GENEVA_matchid
Item
NHS/HPFS: GENEVA_ID of the case in a matched case-control set
text
C0024907 (UMLS CUI [1,1])
C2348585 (UMLS CUI [1,2])
rtype
Item
NHS/HPFS/GEP: Case type based on combination of elevated intraocular pressure (IOP)(defined as maximum intraocular pressure >= 22 mm Hg) and reproducible visual field (VF) loss. For cases only.
text
C0868928 (UMLS CUI [1,1])
C0332307 (UMLS CUI [1,2])
C5394538 (UMLS CUI [1,3])
C3887875 (UMLS CUI [1,4])
dateofextraction
Item
NHS/HPFS/GEP: Year of DNA extraction (should be used with the "site", "spec" and "methodofextraction" variables)
text
C0439234 (UMLS CUI [1,1])
C0012854 (UMLS CUI [1,2])
C0185115 (UMLS CUI [1,3])
Item
NHS/HPFS/GEP: DNA extraction method
string
C0012854 (UMLS CUI [1,1])
C0449341 (UMLS CUI [1,2])
Code List
NHS/HPFS/GEP: DNA extraction method
Item
NHS/HPFS/GEP: Type specimen from which DNA extracted
string
C0456204 (UMLS CUI [1,1])
C0012854 (UMLS CUI [1,2])
C0185115 (UMLS CUI [1,3])
Code List
NHS/HPFS/GEP: Type specimen from which DNA extracted
agedx
Item
NHS/HPFS: Cases: age at index date (glaucoma diagnosis). Controls: 1) if matched to a case (see variable GENEVA_matchid) then age at index date -- matched case's diagnosis date 2) if not matched to a case (variable GENEVA_matchid is missing) then age
text
C1698493 (UMLS CUI [1,1])
C0001779 (UMLS CUI [1,2])
C2316983 (UMLS CUI [1,3])
C0017601 (UMLS CUI [1,4])
C0009932 (UMLS CUI [2,1])
C0150103 (UMLS CUI [2,2])
C0001779 (UMLS CUI [2,3])
C2316983 (UMLS CUI [2,4])
C0017601 (UMLS CUI [2,5])
C1698493 (UMLS CUI [2,6])
C0009932 (UMLS CUI [3,1])
C1298908 (UMLS CUI [3,2])
C0150103 (UMLS CUI [3,3])
C0001779 (UMLS CUI [3,4])
hgla
Item
NHS/HPFS: Family history of glaucoma in 1st degree relatives (defined as history of glaucoma in biological parents, siblings or children). GEP: Family history of glaucoma in parents or siblings
text
C0241889 (UMLS CUI [1,1])
C0017601 (UMLS CUI [1,2])
C1517194 (UMLS CUI [1,3])
C0522476 (UMLS CUI [1,4])
gender
Item
NHS/HPFS/GEP: Gender
text
C0079399 (UMLS CUI [1,1])
sdbh
Item
NHS/HPFS/GEP: Self-report of history of diabetes mellitus
text
C2700446 (UMLS CUI [1,1])
C0262926 (UMLS CUI [1,2])
C0011849 (UMLS CUI [1,3])
hbph
Item
NHS/HPFS/GEP: Self-report of history of systemic hypertension
text
C2700446 (UMLS CUI [1,1])
C0262926 (UMLS CUI [1,2])
C0020538 (UMLS CUI [1,3])
packyr
Item
NHS/HPFS: Cigarette smoking (pack years) as of index date. For NHS/HPFS only.
text
C1277691 (UMLS CUI [1,1])
C4687439 (UMLS CUI [1,2])
smkst
Item
NHS/HPFS/GEP: Cigarette smoking status as of index date (NHS/HPFS) or at enrollment (GEP)
text
C1519386 (UMLS CUI [1,1])
C4687439 (UMLS CUI [1,2])
C1519386 (UMLS CUI [2,1])
C1516879 (UMLS CUI [2,2])
bmi
Item
NHS/HPFS: BMI (kg/m2) averaged over all questionnaires as of index date. For NHS/HPFS only.
text
C1305855 (UMLS CUI [1,1])
C0034394 (UMLS CUI [1,2])
C4687439 (UMLS CUI [1,3])
weight
Item
NHS/HPFS: Weight (lbs) averaged over all questionnaires as of index date. For NHS/HPFS only.
text
C0005910 (UMLS CUI [1,1])
C0034394 (UMLS CUI [1,2])
C4687439 (UMLS CUI [1,3])
height
Item
NHS/HPFS: Height (inches) averaged over all questionnaires as of index date. For NHS/HPFS only.
text
C0005890 (UMLS CUI [1,1])
C0034394 (UMLS CUI [1,2])
C4687439 (UMLS CUI [1,3])
phy
Item
NHS/HPFS: Physical activity (Met-hours/week) averaged over all questionnaires as of index date. For NHS/HPFS only.
text
C0026606 (UMLS CUI [1,1])
C0034394 (UMLS CUI [1,2])
C4687439 (UMLS CUI [1,3])
caff
Item
NHS/HPFS: caffeine intake (mg per day) averaged over all questionnaires as of index date. For NHS/HPFS only.
text
C4062719 (UMLS CUI [1,1])
C0034394 (UMLS CUI [1,2])
C4687439 (UMLS CUI [1,3])
alco
Item
NHS/HPFS: alcohol intake (g per day) average over all questionnaires as of index date. For NHS/HPFS only.
text
C1287509 (UMLS CUI [1,1])
C0034394 (UMLS CUI [1,2])
C4687439 (UMLS CUI [1,3])
gly
Item
NHS/HPFS: glycemic load: average over all questionnaires as of index date.
text
C4042927 (UMLS CUI [1,1])
C0034394 (UMLS CUI [1,2])
C4687439 (UMLS CUI [1,3])
tfat
Item
NHS/HPFS: energy adjusted total fat intake intake (g per day) averaged over all questionnaires as of index date. For NHS/HPFS only.
text
C2183367 (UMLS CUI [1,1])
C0034394 (UMLS CUI [1,2])
C4687439 (UMLS CUI [1,3])
pfn6
Item
NHS/HPFS: energy adjusted total omega-6 polyunsaturated fat intake (g per day) averaged over all questionnaires as of index date. For NHS/HPFS only.
text
C0556122 (UMLS CUI [1,1])
C0034394 (UMLS CUI [1,2])
C4687439 (UMLS CUI [1,3])
C0133860 (UMLS CUI [1,4])
pfn3
Item
NHS/HPFS: energy adjusted total omega-3 polyunsaturated fat intake (g per day) averaged over all questionnaires as of index date. For NHS/HPFS only.
text
C0015689 (UMLS CUI [1,1])
C0556122 (UMLS CUI [1,2])
C0034394 (UMLS CUI [1,3])
C4687439 (UMLS CUI [1,4])
antxsc
Item
NHS/HPFS: Total antioxidant score: average over all questionnaires as of index date. For NHS/HPFS only.
text
C1148564 (UMLS CUI [1,1])
C0449820 (UMLS CUI [1,2])
C0034394 (UMLS CUI [1,3])
C4687439 (UMLS CUI [1,4])
race
Item
NHS/HPFS/GEP: Race
text
C0034510 (UMLS CUI [1,1])
caco
Item
NHS/HPFS/GEP: Case or control status
text
C3274646 (UMLS CUI [1,1])
Item
NHS/HPFS/GEP: Study site
text
C2825164 (UMLS CUI [1,1])
Code List
NHS/HPFS/GEP: Study site
ethn
Item
NHS/HPFS/GEP: Ethnicity
text
C0015031 (UMLS CUI [1,1])
prob1
Item
NHS/HPFS/GEP: Variable used to flag problematic cases or controls who can be excluded in secondary analyses.
text
C1708067 (UMLS CUI [1,1])
C3274646 (UMLS CUI [1,2])
C0680251 (UMLS CUI [1,3])
C0683944 (UMLS CUI [1,4])
consenttype
Item
NHS/HPFS/GEP: Consent coverage
text
C0021430 (UMLS CUI [1,1])
ageenroll
Item
GEP: Cases: age at enrollment (enrollment was after diagnosis). Controls: age at enrollment (same value as agedx). For GEP only.
text
C1698493 (UMLS CUI [1,1])
C0001779 (UMLS CUI [1,2])
C0011008 (UMLS CUI [1,3])
C1516879 (UMLS CUI [1,4])
C0009932 (UMLS CUI [2,1])
C0001779 (UMLS CUI [2,2])
C0011008 (UMLS CUI [2,3])
C1516879 (UMLS CUI [2,4])
odvfpa
Item
NHS/HPFS/GEP: Cases: Zone of VF loss OD on earliest VF indicates paracentral loss. For cases only.
text
C1698493 (UMLS CUI [1,1])
C1710706 (UMLS CUI [1,2])
C3887875 (UMLS CUI [1,3])
C1279919 (UMLS CUI [1,4])
C0271197 (UMLS CUI [1,5])
osvfpa
Item
NHS/HPFS/GEP: Cases: Zone of VF loss OS on earliest VF indicates paracentral loss. For cases only.
text
C1698493 (UMLS CUI [1,1])
C1710706 (UMLS CUI [1,2])
C3887875 (UMLS CUI [1,3])
C1279919 (UMLS CUI [1,4])
C0271197 (UMLS CUI [1,5])
odvfpe
Item
NHS/HPFS/GEP: Cases: Zone of VF loss OD on earliest VF indicates peripheral loss (nasal step. nasal depression. temporal wedge). For cases only.
text
C1698493 (UMLS CUI [1,1])
C1710706 (UMLS CUI [1,2])
C3887875 (UMLS CUI [1,3])
C0241688 (UMLS CUI [1,4])
osvfpe
Item
NHS/HPFS/GEP: Cases: Zone of VF loss OS on earliest VF indicates peripheral loss (nasal step. nasal depression. temporal wedge). For cases only.
text
C1698493 (UMLS CUI [1,1])
C1710706 (UMLS CUI [1,2])
C3887875 (UMLS CUI [1,3])
C0241688 (UMLS CUI [1,4])
odiop
Item
NHS/HPFS: Cases: Maximum untreated intraocular pressure (IOP) in right eye (OD). For cases only. GEP: IOP in OD at enrollment
text
C1698493 (UMLS CUI [1,1])
C0806909 (UMLS CUI [1,2])
C0332155 (UMLS CUI [1,3])
C0578862 (UMLS CUI [1,4])
C0229089 (UMLS CUI [1,5])
C0578862 (UMLS CUI [2,1])
C0011008 (UMLS CUI [2,2])
C1516879 (UMLS CUI [2,3])
osiop
Item
NHS/HPFS: Cases: Maximum untreated intraocular pressure (IOP) in left eye (OS). For cases only. GEP: IOP in OS at enrollment.
text
C1698493 (UMLS CUI [1,1])
C0806909 (UMLS CUI [1,2])
C0578862 (UMLS CUI [1,3])
C0332155 (UMLS CUI [1,4])
C0229090 (UMLS CUI [1,5])
C0578862 (UMLS CUI [2,1])
C0011008 (UMLS CUI [2,2])
C1516879 (UMLS CUI [2,3])
odvfpsd
Item
NHS/HPFS/GEP: Cases: Pattern Standard Deviation (PSD) on earliest VF OD. For cases only.
text
C1698493 (UMLS CUI [1,1])
C1720055 (UMLS CUI [1,2])
C1279919 (UMLS CUI [1,3])
C3887875 (UMLS CUI [1,4])
osvfpsd
Item
NHS/HPFS/GEP: Cases: Pattern Standard Deviation (PSD) on earliest VF OS. For cases only.
text
C1698493 (UMLS CUI [1,1])
C1720055 (UMLS CUI [1,2])
C1279919 (UMLS CUI [1,3])
C3887875 (UMLS CUI [1,4])
odvcdr
Item
NHS/HPFS: Cases: Recent vertical cup:disc ratio in right eye (OD). For cases only. GEP: Vertical cup:disc ratio OD at enrollment
text
C1698493 (UMLS CUI [1,1])
C0332185 (UMLS CUI [1,2])
C1299676 (UMLS CUI [1,3])
C0229089 (UMLS CUI [1,4])
C1299676 (UMLS CUI [2,1])
C0011008 (UMLS CUI [2,2])
C1516879 (UMLS CUI [2,3])
osvcdr
Item
NHS/HPFS: Cases: Recent vertical cup:disc ratio in left eye (OS). For cases only. GEP: Vertical cup:disc ratio OS at enrollment.
text
C1698493 (UMLS CUI [1,1])
C0332185 (UMLS CUI [1,2])
C1299676 (UMLS CUI [1,3])
C0229090 (UMLS CUI [1,4])
C1299676 (UMLS CUI [2,1])
C0011008 (UMLS CUI [2,2])
C1516879 (UMLS CUI [2,3])
hbphace
Item
NHS/HPFS: Systemic ACE use as of index date. GEP: Systemic ACE use at DNA collection date.
text
C1524063 (UMLS CUI [1,1])
C0003015 (UMLS CUI [1,2])
C4687439 (UMLS CUI [1,3])
C1524063 (UMLS CUI [2,1])
C0003015 (UMLS CUI [2,2])
C0012854 (UMLS CUI [2,3])
C0200345 (UMLS CUI [2,4])
hbphbbl
Item
NHS/HPFS: Systemic Beta Blocker use as of index date. GEP: Systemic Beta Blocker use at DNA collection date
text
C1524063 (UMLS CUI [1,1])
C0001645 (UMLS CUI [1,2])
C4687439 (UMLS CUI [1,3])
C1524063 (UMLS CUI [2,1])
C0001645 (UMLS CUI [2,2])
C0200345 (UMLS CUI [2,3])
C0012854 (UMLS CUI [2,4])
hbphccb
Item
NHS/HPFS: Systemic Calcium channel blocker use as of index date. GEP: Systemic Calcium channel blocker use at DNA collection.
text
C1524063 (UMLS CUI [1,1])
C0006684 (UMLS CUI [1,2])
C4687439 (UMLS CUI [1,3])
C1524063 (UMLS CUI [2,1])
C0006684 (UMLS CUI [2,2])
C0200345 (UMLS CUI [2,3])
C0012854 (UMLS CUI [2,4])
eyesxltp
Item
NHS/HPFS/GEP: Cases: History of laser trabeculoplasty in either eye. For cases only.
text
C1698493 (UMLS CUI [1,1])
C0262926 (UMLS CUI [1,2])
C0395482 (UMLS CUI [1,3])
eyesxgfs
Item
NHS/HPFS/GEP: Cases: History of trabeculectomy, angle surgery (s.a. trabectome) or glaucoma drainage device implant in either eye. For cases only.
text
C1698493 (UMLS CUI [1,1])
C0262926 (UMLS CUI [1,2])
C0395482 (UMLS CUI [1,3])
C0543467 (UMLS CUI [1,4])
C0229238 (UMLS CUI [1,5])
C0877318 (UMLS CUI [1,6])
C0580747 (UMLS CUI [1,7])