The data table (n=49 variables) contains information from AREDS participants' fundus photographs, including presence, type, and extent of drusen, presence/extent of RPE depigmentation, SSR (serous sensory retinal) detachments, subretinal hemorrhages, subretinal fibrosis, and geographic atrophy. In addition, information on photocoagulation (PC) treatment for AMD SRNV is included, as well as AMD Severity Scale Scores and AMD Simple Scale Scores calculated from the fundus data. Note: In version 3, the ID has been replaced by ID2 identifier for all subjects.

  1. StudyEvent: NEI Age-Related Eye Disease Study (AREDS)
    1. Eligibility Criteria
    2. The data table (n=142 variables) contains AMD and cataract phenotype information, medical history and socio-demographic information drawn from several data sets (e.g. enrollment_randomization, amdlensphenotype, followup), plus a unique patient identifier (ID2) for participants with a genetic specimen (to be found only in GENSPECPHENOTYPE and GENSPECFUNDUSLENS [pht000376] tables). Nuclear, cortical and posterior subcapsular opacity information is included for both eyes at baseline and end of study. Other disease information (e.g. diabetes, cancer, angina), medical information (e.g. BMI, blood pressure) and smoking status are also included annually throughout follow-up.
    3. The data table (n=12 variables) contains information about the occurrence of adverse events during the AREDS clinical trial, e.g. type of adverse event, severity, primary ICD9 code, outcome, potential relationship to study drug, timing, and treatment. Data were collected through the clinical trial and for the first 6 months of the natural history follow-up immediately after the clinical trial concluded. Note: In version 3, the ID has been replaced by ID2 identifier for all subjects.
    4. The data table (n=25 variables) contains detailed information about cataract phenotypes (n=23 variables) as well as final AMD phenotype (n=1 variable), and patient ID. Nuclear, cortical and posterior subcapsular opacity information is included for both eyes at baseline and end of study. Note: In version 3, the ID has been replaced by ID2 identifier for all subjects.
    5. The data table (n=56 variables) contains information about AREDS participants' dietary intake of alcohol, amino acids, carbohydrates, fiber, poly- and monounsaturated fatty acids, proteins, vitamins and minerals. Participants' glycemic index and glycemic load are also included. Note: In version 3, the ID has been replaced by ID2 identifier for all subjects.
    6. The data table (n=102 variables) contains AREDS treatment assignment, basic socio-demographic characteristics and baseline medical history for AREDS participants. Medical history information includes eye disease information such as AMD Category, visual acuity, and past ophthalmic treatments (e.g. cataract surgery, laser treatment), as well as information about the presence/absence of other diseases (e.g. angina, arthritis, cancer, diabetes, high blood pressure), use of prescribed drugs for disease management (e.g. blood-thinning medications, digoxin, thyroid hormones, insulin), use of over-the-counter drugs (e.g. NSAIDs, antacids), intake of vitamins and minerals, and smoking history. Note: In version 3, the ID has been replaced by ID2 identifier for all subjects.
    7. The data table (n=83 variables) contains information obtained at follow-up visits during the AREDS clinical trial (every six months following randomization), annually in person during the natural history follow-up, and via phone between annual in-person visits. Variables include information about AREDS participants' ophthalmic medical history (e.g. cataract or other eye surgery, laser treatment for AMD, retinal repair, capsulotomy, presence/absence of lens, glaucoma, and visual acuity) and general medical information, including new diagnoses of cancer, heart disease, stroke, and peripheral vascular disease, disease history of angina and high blood pressure, current disease status of diabetes, arthritis, and gout, use of prescribed drugs for disease treatment or management (e.g. blood-thinning medications, digoxin, thyroid hormones, insulin), use of over-the-counter drugs (e.g. NSAIDs, antacids), and smoking behavior. For version 3 release of the study, visual acuity data of the right eye have been added for odd-numbered visits. Note: In version 3, the ID has been replaced by ID2 identifier for all subjects.
    8. The data table (n=49 variables) contains information from AREDS participants' fundus photographs, including presence, type, and extent of drusen, presence/extent of RPE depigmentation, SSR (serous sensory retinal) detachments, subretinal hemorrhages, subretinal fibrosis, and geographic atrophy. In addition, information on photocoagulation (PC) treatment for AMD SRNV is included, as well as AMD Severity Scale Scores and AMD Simple Scale Scores calculated from the fundus data. Note: In version 3, the ID has been replaced by ID2 identifier for all subjects.
    9. The data table (n=62) contains information only for AREDS participants who have a genetic specimen. A unique patient identifier (ID2 field) for these participants (to be found only in GENSPECPHENOTYPE [pht000001.v2.p1] and GENSPECFUNDUSLENS data tables) is included instead of the patient identifier used for data tables with all participants (ID field). Information about fundus and lens characteristics are included as follows - fundus: presence, type, and extent of drusen, presence/extent of RPE depigmentation, SSR (serous sensory retinal) detachments, subretinal hemorrhages, subretinal fibrosis, and geographic atrophy; lens: degree of nuclear sclerosis, cortical and posterior subcapsular opacities, and iris pigmentation. In addition, information on photocoagulation (PC) treatment for AMD is included as well as AMD Severity Scale Scores and AMD Simple Scale Scores calculated from the fundus data.
    10. The data table (n=6 variables) contains information about AREDS participant hospitalizations (e.g. reason, time from randomization, duration, primary ICD9 code) during the entire study. Note: In version 3, the ID has been replaced by ID2 identifier for all subjects.
    11. The data table (n=21 variables) contains information from AREDS participants' lens photographs, including degree of nuclear sclerosis, cortical and posterior subcapsular opacities, and iris pigmentation. Note: In version 3, the ID has been replaced by ID2 identifier for all subjects.
    12. The data table (n=7 variables) contains information about AREDS participant deaths (e.g. cause, time from randomization) during the entire study. A search using the National Death Index (NDI) yielded additional deaths not identified during the study. Note: In version 3, the ID has been replaced by ID2 identifier for all subjects.
    13. The data table (n=44 variables) contains information about AREDS participants' use (e.g. type, frequency, dose, duration) of non-steroidal anti-inflammatory drugs (e.g. aspirin, ibuprofen, acetaminophen, naproxen). Data were collected at in-clinic visits starting in October 2004. Note: In version 3, the ID has been replaced by ID2 identifier for all subjects.
    14. The data table (n=16 variables) contains information about AREDS participants' general vision status (e.g. general vision score, ocular pain score, VFQ overall score), and its effect on participants' behavior (e.g. near and distant activities, social activities, driving, mental health score) as obtained through the VFQ-25 questionnaire. Note: In version 3, the ID has been replaced by ID2 identifier for all subjects.
    15. Subject - Consent Information
    16. Subject - Sample Mapping (including mapping to Coriell IDs)
    17. The data table (n=2 variables) contains information on subjects' annual exposure to sunlight (hours; April through September).
    18. This dataset provides refractive error values obtained from control subjects of the AREDS study (phs000001.v3.p1) and represents a substudy of AREDS ; data of n=7 new variables are provided in addition to basic sociodemographic data. Subject - consent and subject - sample mapping information is available through phs000001.v3.p1.
    19. This dataset provides refractive error values obtained from control subjects of the AREDS study (phs000001.v3.p1) and represents a substudy of AREDS ; data of n=7 new variables are provided in addition to basic sociodemographic data. Subject - consent and subject - sample mapping information is available through phs000001.v3.p1.
pht000375
Beskrivning

pht000375

DUMMY ID NUMBER
Beskrivning

ID2

Datatyp

string

Alias
UMLS CUI [1,1]
C2348585
STUDY VISIT NUMBER (ALL PARTICIPANTS)
Beskrivning

VISNO

Datatyp

text

Alias
UMLS CUI [1,1]
C0545082
UMLS CUI [1,2]
C2603343
UMLS CUI [1,3]
C2348585
UMLS CUI [2,1]
C0681850
UMLS CUI [2,2]
C0444868
DRUSENOID PED FIELD 2 RT EYE (ALL PARTICIPANTS)
Beskrivning

REDRUSF2

Datatyp

text

Alias
UMLS CUI [1,1]
C0339546
UMLS CUI [1,2]
C1260959
UMLS CUI [1,3]
C0229089
UMLS CUI [2,1]
C0681850
UMLS CUI [2,2]
C0444868
NON-DRUSENOID PED FIELD 2 RT EYE (ALL PARTICIPANTS)
Beskrivning

RENDRUF2

Datatyp

text

Alias
UMLS CUI [1,1]
C0339546
UMLS CUI [1,2]
C1298908
UMLS CUI [1,3]
C1260959
UMLS CUI [1,4]
C0229089
UMLS CUI [2,1]
C0681850
UMLS CUI [2,2]
C0444868
SSR/HEMORRHAGIC RD FIELD 2 RT EYE (ALL PARTICIPANTS)
Beskrivning

RESSRF2

Datatyp

text

Alias
UMLS CUI [1,1]
C0035305
UMLS CUI [1,2]
C0035317
UMLS CUI [1,3]
C0229089
UMLS CUI [2,1]
C0681850
UMLS CUI [2,2]
C0444868
HARD EXUDATE FIELD 2 RT EYE (ALL PARTICIPANTS)
Beskrivning

REHDEXF2

Datatyp

text

Alias
UMLS CUI [1,1]
C0015388
UMLS CUI [1,2]
C4050071
UMLS CUI [1,3]
C0229089
UMLS CUI [2,1]
C0681850
UMLS CUI [2,2]
C0444868
SUBRETINAL/SUBRPE HEMORRHAGE FIELD 2 RT EYE (ALL PARTICIPANTS)
Beskrivning

RESUBHF2

Datatyp

text

Alias
UMLS CUI [1,1]
C0271049
UMLS CUI [1,2]
C0229089
UMLS CUI [2,1]
C0681850
UMLS CUI [2,2]
C0444868
SUBRETINAL FIBROSIS FIELD 2 RT EYE (ALL PARTICIPANTS)
Beskrivning

RESUBFF2

Datatyp

text

Alias
UMLS CUI [1,1]
C0423434
UMLS CUI [1,2]
C0229089
UMLS CUI [2,1]
C0681850
UMLS CUI [2,2]
C0444868
PC/AMD FIELD 2 RT EYE (ALL PARTICIPANTS)
Beskrivning

REPHCOF2

Datatyp

text

Alias
UMLS CUI [1,1]
C0242383
UMLS CUI [1,2]
C0042826
UMLS CUI [1,3]
C0229089
UMLS CUI [2,1]
C0681850
UMLS CUI [2,2]
C0444868
GEOGRAPHIC ATROPHY CENTER POINT RT EYE (ALL PARTICIPANTS)
Beskrivning

REGEOACT

Datatyp

text

Alias
UMLS CUI [1,1]
C1536085
UMLS CUI [1,2]
C0205099
UMLS CUI [1,3]
C0229089
UMLS CUI [2,1]
C0681850
UMLS CUI [2,2]
C0444868
GEOGRAPHIC ATROPHY AREA C/SUB RT EYE (ALL PARTICIPANTS)
Beskrivning

REGEOACS

Datatyp

text

Alias
UMLS CUI [1,1]
C1536085
UMLS CUI [1,2]
C0205146
UMLS CUI [1,3]
C0229089
UMLS CUI [2,1]
C0681850
UMLS CUI [2,2]
C0444868
GEOGRAPHIC ATROPHY W/I GRID RT EYE (ALL PARTICIPANTS)
Beskrivning

REGEOAWI

Datatyp

text

Alias
UMLS CUI [1,1]
C1536085
UMLS CUI [1,2]
C0229089
UMLS CUI [1,3]
C0491832
UMLS CUI [2,1]
C0681850
UMLS CUI [2,2]
C0444868
RPE DEPIGMENTATION AREA C/SUB+INNERS RT EYE (ALL PARTICIPANTS)
Beskrivning

RERPEDCI

Datatyp

text

Alias
UMLS CUI [1,1]
C0151891
UMLS CUI [1,2]
C0205146
UMLS CUI [1,3]
C0229089
UMLS CUI [2,1]
C0681850
UMLS CUI [2,2]
C0444868
RPE DEPIGMENTATION AREA W/I GRID RT EYE (ALL PARTICIPANTS)
Beskrivning

RERPEDWI

Datatyp

text

Alias
UMLS CUI [1,1]
C0229089
UMLS CUI [1,2]
C0151891
UMLS CUI [1,3]
C0205146
UMLS CUI [2,1]
C0681850
UMLS CUI [2,2]
C0444868
INCREASED PIGMENT AREA C/SUB+INNERS RT EYE (ALL PARTICIPANTS)
Beskrivning

REINCPCI

Datatyp

text

Alias
UMLS CUI [1,1]
C3163633
UMLS CUI [1,2]
C0031916
UMLS CUI [1,3]
C0205146
UMLS CUI [2,1]
C0681850
UMLS CUI [2,2]
C0444868
INCREASED PIGMENT AREA W/I GRID RT EYE (ALL PARTICIPANTS)
Beskrivning

REINCPWI

Datatyp

text

Alias
UMLS CUI [1,1]
C3163633
UMLS CUI [1,2]
C0031916
UMLS CUI [1,3]
C0205146
UMLS CUI [1,4]
C0430942
UMLS CUI [1,5]
C0229089
UMLS CUI [2,1]
C0681850
UMLS CUI [2,2]
C0444868
MAXIMUM DRUSEN SIZE W/I GRID RT EYE (ALL PARTICIPANTS)
Beskrivning

REDRSZWI

Datatyp

text

Alias
UMLS CUI [1,1]
C0806909
UMLS CUI [1,2]
C1260959
UMLS CUI [1,3]
C0456389
UMLS CUI [1,4]
C0430942
UMLS CUI [1,5]
C0229089
UMLS CUI [2,1]
C0681850
UMLS CUI [2,2]
C0444868
SOFT DRUSEN RT EYE (ALL PARTICIPANTS)
Beskrivning

REDRSOFT

Datatyp

text

Alias
UMLS CUI [1,1]
C0229089
UMLS CUI [1,2]
C0205358
UMLS CUI [1,3]
C1260959
UMLS CUI [2,1]
C0681850
UMLS CUI [2,2]
C0444868
DRUSEN AREA W/I GRID (ALL PARTICIPANTS)
Beskrivning

REDRARWI

Datatyp

text

Alias
UMLS CUI [1,1]
C0035312
UMLS CUI [1,2]
C0205146
UMLS CUI [1,3]
C0491832
UMLS CUI [2,1]
C0681850
UMLS CUI [2,2]
C0444868
RETICULAR DRUSEN RT EYE (ALL PARTICIPANTS)
Beskrivning

REDRRETI

Datatyp

text

Alias
UMLS CUI [1,1]
C1260959
UMLS CUI [1,2]
C0229089
UMLS CUI [2,1]
C0681850
UMLS CUI [2,2]
C0444868
CALCIFIED DRUSEN W/I OR OUTSIDE GRID RT EYE (ALL PARTICIPANTS)
Beskrivning

REDRCALC

Datatyp

text

Alias
UMLS CUI [1,1]
C0229089
UMLS CUI [1,2]
C0175895
UMLS CUI [1,3]
C1260959
UMLS CUI [1,4]
C0491832
UMLS CUI [2,1]
C0681850
UMLS CUI [2,2]
C0444868
DRUSEN CATEGORY RT EYE (ALL PARTICIPANTS)
Beskrivning

REELICAT

Datatyp

text

Alias
UMLS CUI [1,1]
C1260959
UMLS CUI [1,2]
C0683312
UMLS CUI [1,3]
C0229089
UMLS CUI [2,1]
C0681850
UMLS CUI [2,2]
C0444868
DRUSENOID PED FIELD 2 LT EYE (ALL PARTICIPANTS)
Beskrivning

LEDRUSF2

Datatyp

text

Alias
UMLS CUI [1,1]
C0229090
UMLS CUI [1,2]
C1260959
UMLS CUI [1,3]
C0339546
UMLS CUI [1,4]
C0042826
UMLS CUI [2,1]
C0681850
UMLS CUI [2,2]
C0444868
NON-DRUSENOID PED FIELD 2 LT EYE (ALL PARTICIPANTS)
Beskrivning

LENDRUF2

Datatyp

text

Alias
UMLS CUI [1,1]
C0229090
UMLS CUI [1,2]
C1298908
UMLS CUI [1,3]
C1260959
UMLS CUI [1,4]
C0339546
UMLS CUI [1,5]
C0042826
UMLS CUI [2,1]
C0681850
UMLS CUI [2,2]
C0444868
SSR/HEMORRHAGIC RD FIELD 2 LT EYE (ALL PARTICIPANTS)
Beskrivning

LESSRF2

Datatyp

text

Alias
UMLS CUI [1,1]
C0035305
UMLS CUI [1,2]
C0035317
UMLS CUI [1,3]
C0229089
UMLS CUI [2,1]
C0681850
UMLS CUI [2,2]
C0444868
HARD EXUDATE FIELD 2 LT EYE (ALL PARTICIPANTS)
Beskrivning

LEHDEXF2

Datatyp

text

Alias
UMLS CUI [1,1]
C0229090
UMLS CUI [1,2]
C0018599
UMLS CUI [1,3]
C0015388
UMLS CUI [1,4]
C0042826
UMLS CUI [2,1]
C0681850
UMLS CUI [2,2]
C0444868
SUBRETINAL/SUBRPE HEMORRHAGE FIELD 2 LT EYE (ALL PARTICIPANTS)
Beskrivning

LESUBHF2

Datatyp

text

Alias
UMLS CUI [1,1]
C0019080
UMLS CUI [1,2]
C0229090
UMLS CUI [1,3]
C2699708
UMLS CUI [1,4]
C0042826
UMLS CUI [2,1]
C0681850
UMLS CUI [2,2]
C0444868
SUBRETINAL FIBROSIS FIELD 2 LT EYE (ALL PARTICIPANTS)
Beskrivning

LESUBFF2

Datatyp

text

Alias
UMLS CUI [1,1]
C0229090
UMLS CUI [1,2]
C2699708
UMLS CUI [1,3]
C0016059
UMLS CUI [2,1]
C0681850
UMLS CUI [2,2]
C0444868
PC/AMD FIELD 2 LT EYE (ALL PARTICIPANTS)
Beskrivning

LEPHCOF2

Datatyp

text

Alias
UMLS CUI [1,1]
C0242383
UMLS CUI [1,2]
C0042826
UMLS CUI [1,3]
C0229090
UMLS CUI [2,1]
C0681850
UMLS CUI [2,2]
C0444868
GEOGRAPHIC ATROPHY CENTER POINT LT EYE (ALL PARTICIPANTS)
Beskrivning

LEGEOACT

Datatyp

text

Alias
UMLS CUI [1,1]
C1536085
UMLS CUI [1,2]
C0205099
UMLS CUI [1,3]
C0229090
UMLS CUI [2,1]
C0681850
UMLS CUI [2,2]
C0444868
GEOGRAPHIC ATROPHY AREA C/SUB LT EYE (ALL PARTICIPANTS)
Beskrivning

LEGEOACS

Datatyp

text

Alias
UMLS CUI [1,1]
C1536085
UMLS CUI [1,2]
C0205099
UMLS CUI [1,3]
C0229090
UMLS CUI [2,1]
C0681850
UMLS CUI [2,2]
C0444868
GEOGRAPHIC ATROPHY W/I GRID LT EYE (ALL PARTICIPANTS)
Beskrivning

LEGEOAWI

Datatyp

text

Alias
UMLS CUI [1,1]
C1536085
UMLS CUI [1,2]
C0205099
UMLS CUI [1,3]
C0229090
UMLS CUI [2,1]
C0681850
UMLS CUI [2,2]
C0444868
RPE DEPIGMENTATION AREA C/SUB+INNERS LT EYE (ALL PARTICIPANTS)
Beskrivning

LERPEDCI

Datatyp

text

Alias
UMLS CUI [1,1]
C0151891
UMLS CUI [1,2]
C0205146
UMLS CUI [1,3]
C0229090
UMLS CUI [2,1]
C0681850
UMLS CUI [2,2]
C0444868
RPE DEPIGMENTATION AREA W/I GRID LT EYE (ALL PARTICIPANTS)
Beskrivning

LERPEDWI

Datatyp

text

Alias
UMLS CUI [1,1]
C0151891
UMLS CUI [1,2]
C0205146
UMLS CUI [1,3]
C0229090
UMLS CUI [2,1]
C0681850
UMLS CUI [2,2]
C0444868
INCREASED PIGMENT AREA C/SUB+INNERS LT EYE (ALL PARTICIPANTS)
Beskrivning

LEINCPCI

Datatyp

text

Alias
UMLS CUI [1,1]
C3163633
UMLS CUI [1,2]
C0031916
UMLS CUI [1,3]
C0205146
UMLS CUI [1,4]
C0229090
UMLS CUI [2,1]
C0681850
UMLS CUI [2,2]
C0444868
INCREASED PIGMENT AREA W/I GRID LT EYE (ALL PARTICIPANTS)
Beskrivning

LEINCPWI

Datatyp

text

Alias
UMLS CUI [1,1]
C3163633
UMLS CUI [1,2]
C0031916
UMLS CUI [1,3]
C0205146
UMLS CUI [1,4]
C0229090
UMLS CUI [2,1]
C0681850
UMLS CUI [2,2]
C0444868
MAXIMUM DRUSEN SIZE W/I GRID LT EYE (ALL PARTICIPANTS)
Beskrivning

LEDRSZWI

Datatyp

text

Alias
UMLS CUI [1,1]
C0806909
UMLS CUI [1,2]
C1260959
UMLS CUI [1,3]
C0456389
UMLS CUI [1,4]
C0430942
UMLS CUI [1,5]
C0229090
UMLS CUI [2,1]
C0681850
UMLS CUI [2,2]
C0444868
SOFT DRUSEN LT EYE (ALL PARTICIPANTS)
Beskrivning

LEDRSOFT

Datatyp

text

Alias
UMLS CUI [1,1]
C0205358
UMLS CUI [1,2]
C1260959
UMLS CUI [1,3]
C0229090
UMLS CUI [2,1]
C0681850
UMLS CUI [2,2]
C0444868
DRUSEN AREA W/I GRID LT EYE (ALL PARTICIPANTS)
Beskrivning

LEDRARWI

Datatyp

text

Alias
UMLS CUI [1,1]
C0035312
UMLS CUI [1,2]
C0205146
UMLS CUI [1,3]
C0491832
UMLS CUI [1,4]
C0229090
UMLS CUI [2,1]
C0681850
UMLS CUI [2,2]
C0444868
RETICULAR DRUSEN LT EYE (ALL PARTICIPANTS)
Beskrivning

LEDRRETI

Datatyp

text

Alias
UMLS CUI [1,1]
C1260959
UMLS CUI [1,2]
C0229090
UMLS CUI [2,1]
C0681850
UMLS CUI [2,2]
C0444868
CALCIFIED DRUSEN W/I OR OUTSIDE GRID LT EYE (ALL PARTICIPANTS)
Beskrivning

LEDRCALC

Datatyp

text

Alias
UMLS CUI [1,1]
C0175895
UMLS CUI [1,2]
C1260959
UMLS CUI [1,3]
C0491832
UMLS CUI [1,4]
C0229090
UMLS CUI [2,1]
C0681850
UMLS CUI [2,2]
C0444868
DRUSEN CATEGORY LT EYE (ALL PARTICIPANTS)
Beskrivning

LEELICAT

Datatyp

text

Alias
UMLS CUI [1,1]
C1260959
UMLS CUI [1,2]
C0683312
UMLS CUI [1,3]
C0229090
UMLS CUI [2,1]
C0681850
UMLS CUI [2,2]
C0444868
PARTICIPANT DRUSEN CATEGORY (WORSE EYE; ALL PARTICIPANTS)
Beskrivning

DRUCAT

Datatyp

text

Alias
UMLS CUI [1,1]
C0679646
UMLS CUI [1,2]
C1260959
UMLS CUI [1,3]
C0683312
UMLS CUI [1,4]
C0015392
UMLS CUI [1,5]
C1457868
UMLS CUI [2,1]
C0681850
UMLS CUI [2,2]
C0444868
AMD SEVERITY SCALE SCORE LT EYE (ALL PARTICIPANTS)
Beskrivning

AMDSEVLE

Datatyp

text

Alias
UMLS CUI [1,1]
C0242383
UMLS CUI [1,2]
C1319166
UMLS CUI [1,3]
C0681889
UMLS CUI [1,4]
C0449820
UMLS CUI [1,5]
C0229090
UMLS CUI [2,1]
C0681850
UMLS CUI [2,2]
C0444868
AMD SEVERITY SCALE SCORE RT EYE (ALL PARTICIPANTS)
Beskrivning

AMDSEVRE

Datatyp

text

Alias
UMLS CUI [1,1]
C0242383
UMLS CUI [1,2]
C1319166
UMLS CUI [1,3]
C0229089
UMLS CUI [1,4]
C0681889
UMLS CUI [1,5]
C0449820
UMLS CUI [2,1]
C0681850
UMLS CUI [2,2]
C0444868
AMD SIMPLE SCALE SCORE (PERSON; ALL PARTICIPANTS)
Beskrivning

SCALE

Datatyp

text

Alias
UMLS CUI [1,1]
C0242383
UMLS CUI [1,2]
C0449820
UMLS CUI [1,3]
C0681889
UMLS CUI [2,1]
C0681850
UMLS CUI [2,2]
C0444868
LAST PHOTO IN CLINICAL TRIAL (ALL PARTICIPANTS)
Beskrivning

LASTCLINF

Datatyp

text

Alias
UMLS CUI [1,1]
C2347804
UMLS CUI [1,2]
C1517741
UMLS CUI [1,3]
C0200189
UMLS CUI [2,1]
C0681850
UMLS CUI [2,2]
C0444868
YEARS FROM RANDOMIZATION TO DATE OF FUNDUS PHOTO RT EYE (ALL PARTICIPANTS)
Beskrivning

REPHTIME

Datatyp

float

Måttenheter
  • years
Alias
UMLS CUI [1,1]
C0439234
UMLS CUI [1,2]
C0034656
UMLS CUI [1,3]
C0200189
UMLS CUI [2,1]
C0681850
UMLS CUI [2,2]
C0444868
years
YEARS FROM RANDOMIZATION TO DATE OF FUNDUS PHOTO LT EYE (ALL PARTICIPANTS)
Beskrivning

LEPHTIME

Datatyp

float

Måttenheter
  • years
Alias
UMLS CUI [1,1]
C0439234
UMLS CUI [1,2]
C0034656
UMLS CUI [1,3]
C0200189
UMLS CUI [1,4]
C0229090
UMLS CUI [2,1]
C0681850
UMLS CUI [2,2]
C0444868
years

Similar models

The data table (n=49 variables) contains information from AREDS participants' fundus photographs, including presence, type, and extent of drusen, presence/extent of RPE depigmentation, SSR (serous sensory retinal) detachments, subretinal hemorrhages, subretinal fibrosis, and geographic atrophy. In addition, information on photocoagulation (PC) treatment for AMD SRNV is included, as well as AMD Severity Scale Scores and AMD Simple Scale Scores calculated from the fundus data. Note: In version 3, the ID has been replaced by ID2 identifier for all subjects.

  1. StudyEvent: NEI Age-Related Eye Disease Study (AREDS)
    1. Eligibility Criteria
    2. The data table (n=142 variables) contains AMD and cataract phenotype information, medical history and socio-demographic information drawn from several data sets (e.g. enrollment_randomization, amdlensphenotype, followup), plus a unique patient identifier (ID2) for participants with a genetic specimen (to be found only in GENSPECPHENOTYPE and GENSPECFUNDUSLENS [pht000376] tables). Nuclear, cortical and posterior subcapsular opacity information is included for both eyes at baseline and end of study. Other disease information (e.g. diabetes, cancer, angina), medical information (e.g. BMI, blood pressure) and smoking status are also included annually throughout follow-up.
    3. The data table (n=12 variables) contains information about the occurrence of adverse events during the AREDS clinical trial, e.g. type of adverse event, severity, primary ICD9 code, outcome, potential relationship to study drug, timing, and treatment. Data were collected through the clinical trial and for the first 6 months of the natural history follow-up immediately after the clinical trial concluded. Note: In version 3, the ID has been replaced by ID2 identifier for all subjects.
    4. The data table (n=25 variables) contains detailed information about cataract phenotypes (n=23 variables) as well as final AMD phenotype (n=1 variable), and patient ID. Nuclear, cortical and posterior subcapsular opacity information is included for both eyes at baseline and end of study. Note: In version 3, the ID has been replaced by ID2 identifier for all subjects.
    5. The data table (n=56 variables) contains information about AREDS participants' dietary intake of alcohol, amino acids, carbohydrates, fiber, poly- and monounsaturated fatty acids, proteins, vitamins and minerals. Participants' glycemic index and glycemic load are also included. Note: In version 3, the ID has been replaced by ID2 identifier for all subjects.
    6. The data table (n=102 variables) contains AREDS treatment assignment, basic socio-demographic characteristics and baseline medical history for AREDS participants. Medical history information includes eye disease information such as AMD Category, visual acuity, and past ophthalmic treatments (e.g. cataract surgery, laser treatment), as well as information about the presence/absence of other diseases (e.g. angina, arthritis, cancer, diabetes, high blood pressure), use of prescribed drugs for disease management (e.g. blood-thinning medications, digoxin, thyroid hormones, insulin), use of over-the-counter drugs (e.g. NSAIDs, antacids), intake of vitamins and minerals, and smoking history. Note: In version 3, the ID has been replaced by ID2 identifier for all subjects.
    7. The data table (n=83 variables) contains information obtained at follow-up visits during the AREDS clinical trial (every six months following randomization), annually in person during the natural history follow-up, and via phone between annual in-person visits. Variables include information about AREDS participants' ophthalmic medical history (e.g. cataract or other eye surgery, laser treatment for AMD, retinal repair, capsulotomy, presence/absence of lens, glaucoma, and visual acuity) and general medical information, including new diagnoses of cancer, heart disease, stroke, and peripheral vascular disease, disease history of angina and high blood pressure, current disease status of diabetes, arthritis, and gout, use of prescribed drugs for disease treatment or management (e.g. blood-thinning medications, digoxin, thyroid hormones, insulin), use of over-the-counter drugs (e.g. NSAIDs, antacids), and smoking behavior. For version 3 release of the study, visual acuity data of the right eye have been added for odd-numbered visits. Note: In version 3, the ID has been replaced by ID2 identifier for all subjects.
    8. The data table (n=49 variables) contains information from AREDS participants' fundus photographs, including presence, type, and extent of drusen, presence/extent of RPE depigmentation, SSR (serous sensory retinal) detachments, subretinal hemorrhages, subretinal fibrosis, and geographic atrophy. In addition, information on photocoagulation (PC) treatment for AMD SRNV is included, as well as AMD Severity Scale Scores and AMD Simple Scale Scores calculated from the fundus data. Note: In version 3, the ID has been replaced by ID2 identifier for all subjects.
    9. The data table (n=62) contains information only for AREDS participants who have a genetic specimen. A unique patient identifier (ID2 field) for these participants (to be found only in GENSPECPHENOTYPE [pht000001.v2.p1] and GENSPECFUNDUSLENS data tables) is included instead of the patient identifier used for data tables with all participants (ID field). Information about fundus and lens characteristics are included as follows - fundus: presence, type, and extent of drusen, presence/extent of RPE depigmentation, SSR (serous sensory retinal) detachments, subretinal hemorrhages, subretinal fibrosis, and geographic atrophy; lens: degree of nuclear sclerosis, cortical and posterior subcapsular opacities, and iris pigmentation. In addition, information on photocoagulation (PC) treatment for AMD is included as well as AMD Severity Scale Scores and AMD Simple Scale Scores calculated from the fundus data.
    10. The data table (n=6 variables) contains information about AREDS participant hospitalizations (e.g. reason, time from randomization, duration, primary ICD9 code) during the entire study. Note: In version 3, the ID has been replaced by ID2 identifier for all subjects.
    11. The data table (n=21 variables) contains information from AREDS participants' lens photographs, including degree of nuclear sclerosis, cortical and posterior subcapsular opacities, and iris pigmentation. Note: In version 3, the ID has been replaced by ID2 identifier for all subjects.
    12. The data table (n=7 variables) contains information about AREDS participant deaths (e.g. cause, time from randomization) during the entire study. A search using the National Death Index (NDI) yielded additional deaths not identified during the study. Note: In version 3, the ID has been replaced by ID2 identifier for all subjects.
    13. The data table (n=44 variables) contains information about AREDS participants' use (e.g. type, frequency, dose, duration) of non-steroidal anti-inflammatory drugs (e.g. aspirin, ibuprofen, acetaminophen, naproxen). Data were collected at in-clinic visits starting in October 2004. Note: In version 3, the ID has been replaced by ID2 identifier for all subjects.
    14. The data table (n=16 variables) contains information about AREDS participants' general vision status (e.g. general vision score, ocular pain score, VFQ overall score), and its effect on participants' behavior (e.g. near and distant activities, social activities, driving, mental health score) as obtained through the VFQ-25 questionnaire. Note: In version 3, the ID has been replaced by ID2 identifier for all subjects.
    15. Subject - Consent Information
    16. Subject - Sample Mapping (including mapping to Coriell IDs)
    17. The data table (n=2 variables) contains information on subjects' annual exposure to sunlight (hours; April through September).
    18. This dataset provides refractive error values obtained from control subjects of the AREDS study (phs000001.v3.p1) and represents a substudy of AREDS ; data of n=7 new variables are provided in addition to basic sociodemographic data. Subject - consent and subject - sample mapping information is available through phs000001.v3.p1.
    19. This dataset provides refractive error values obtained from control subjects of the AREDS study (phs000001.v3.p1) and represents a substudy of AREDS ; data of n=7 new variables are provided in addition to basic sociodemographic data. Subject - consent and subject - sample mapping information is available through phs000001.v3.p1.
Name
Typ
Description | Question | Decode (Coded Value)
Datatyp
Alias
Item Group
pht000375
ID2
Item
DUMMY ID NUMBER
string
C2348585 (UMLS CUI [1,1])
Item
STUDY VISIT NUMBER (ALL PARTICIPANTS)
text
C0545082 (UMLS CUI [1,1])
C2603343 (UMLS CUI [1,2])
C2348585 (UMLS CUI [1,3])
C0681850 (UMLS CUI [2,1])
C0444868 (UMLS CUI [2,2])
Code List
STUDY VISIT NUMBER (ALL PARTICIPANTS)
CL Item
Baseline visit (00)
C1442488 (UMLS CUI [1,1])
C0545082 (UMLS CUI [1,2])
CL Item
0.5-year (01)
C0444500 (UMLS CUI [1,1])
C0439234 (UMLS CUI [1,2])
CL Item
1-year (02)
C0205447 (UMLS CUI [1,1])
C0439234 (UMLS CUI [1,2])
CL Item
1.5-years (03)
C0439234 (UMLS CUI [1,1])
CL Item
2-years (04)
C0205448 (UMLS CUI [1,1])
C0439234 (UMLS CUI [1,2])
CL Item
2.5-years (05)
C3844011 (UMLS CUI [1,1])
C0439234 (UMLS CUI [1,2])
CL Item
3-years (06)
C0439234 (UMLS CUI [1,1])
C0205437 (UMLS CUI [1,2])
CL Item
3.5-years (07)
C0439234 (UMLS CUI [1,1])
CL Item
4-years (08)
C0205450 (UMLS CUI [1,1])
C0439234 (UMLS CUI [1,2])
CL Item
4.5-years (09)
C0439234 (UMLS CUI [1,1])
CL Item
5-years (10)
C0205451 (UMLS CUI [1,1])
C0439234 (UMLS CUI [1,2])
CL Item
5.5-years (11)
C0439234 (UMLS CUI [1,1])
CL Item
6-years (12)
C0205452 (UMLS CUI [1,1])
C0439234 (UMLS CUI [1,2])
CL Item
6.5-years (13)
C0439234 (UMLS CUI [1,1])
CL Item
7-years (14)
C0205453 (UMLS CUI [1,1])
C0439234 (UMLS CUI [1,2])
CL Item
7.5-years (15)
C0439234 (UMLS CUI [1,1])
CL Item
8-years (16)
C0205454 (UMLS CUI [1,1])
C0439234 (UMLS CUI [1,2])
CL Item
8.5-years (17)
C0439234 (UMLS CUI [1,1])
CL Item
9-years (18)
C0439234 (UMLS CUI [1,1])
CL Item
9.5-years (19)
C0439234 (UMLS CUI [1,1])
CL Item
10-years (20)
C0439234 (UMLS CUI [1,1])
CL Item
10.5-years (21)
C0439234 (UMLS CUI [1,1])
CL Item
11-years (22)
C0439234 (UMLS CUI [1,1])
CL Item
11.5-years (23)
C0439234 (UMLS CUI [1,1])
CL Item
12-years (24)
C0439234 (UMLS CUI [1,1])
CL Item
12.5-years (25)
C0439234 (UMLS CUI [1,1])
CL Item
13-years (26)
C0439234 (UMLS CUI [1,1])
Item
DRUSENOID PED FIELD 2 RT EYE (ALL PARTICIPANTS)
text
C0339546 (UMLS CUI [1,1])
C1260959 (UMLS CUI [1,2])
C0229089 (UMLS CUI [1,3])
C0681850 (UMLS CUI [2,1])
C0444868 (UMLS CUI [2,2])
Code List
DRUSENOID PED FIELD 2 RT EYE (ALL PARTICIPANTS)
CL Item
None (0)
C0549184 (UMLS CUI [1,1])
CL Item
Questionable (1)
C0332241 (UMLS CUI [1,1])
CL Item
Yes (2)
C1705108 (UMLS CUI [1,1])
CL Item
Cannot grade (8)
C1707258 (UMLS CUI [1,1])
Item
NON-DRUSENOID PED FIELD 2 RT EYE (ALL PARTICIPANTS)
text
C0339546 (UMLS CUI [1,1])
C1298908 (UMLS CUI [1,2])
C1260959 (UMLS CUI [1,3])
C0229089 (UMLS CUI [1,4])
C0681850 (UMLS CUI [2,1])
C0444868 (UMLS CUI [2,2])
Code List
NON-DRUSENOID PED FIELD 2 RT EYE (ALL PARTICIPANTS)
CL Item
None (0)
C0549184 (UMLS CUI [1,1])
CL Item
Questionable (1)
C0332241 (UMLS CUI [1,1])
CL Item
Yes (2)
C1705108 (UMLS CUI [1,1])
CL Item
Cannot grade (8)
C1707258 (UMLS CUI [1,1])
Item
SSR/HEMORRHAGIC RD FIELD 2 RT EYE (ALL PARTICIPANTS)
text
C0035305 (UMLS CUI [1,1])
C0035317 (UMLS CUI [1,2])
C0229089 (UMLS CUI [1,3])
C0681850 (UMLS CUI [2,1])
C0444868 (UMLS CUI [2,2])
Code List
SSR/HEMORRHAGIC RD FIELD 2 RT EYE (ALL PARTICIPANTS)
CL Item
None (0)
C0549184 (UMLS CUI [1,1])
CL Item
Questionable (1)
C0332241 (UMLS CUI [1,1])
CL Item
Yes (2)
C1705108 (UMLS CUI [1,1])
CL Item
Cannot grade (8)
C1707258 (UMLS CUI [1,1])
Item
HARD EXUDATE FIELD 2 RT EYE (ALL PARTICIPANTS)
text
C0015388 (UMLS CUI [1,1])
C4050071 (UMLS CUI [1,2])
C0229089 (UMLS CUI [1,3])
C0681850 (UMLS CUI [2,1])
C0444868 (UMLS CUI [2,2])
Code List
HARD EXUDATE FIELD 2 RT EYE (ALL PARTICIPANTS)
CL Item
None (0)
C0549184 (UMLS CUI [1,1])
CL Item
Questionable (1)
C0332241 (UMLS CUI [1,1])
CL Item
Yes (2)
C1705108 (UMLS CUI [1,1])
CL Item
Cannot grade (8)
C1707258 (UMLS CUI [1,1])
Item
SUBRETINAL/SUBRPE HEMORRHAGE FIELD 2 RT EYE (ALL PARTICIPANTS)
text
C0271049 (UMLS CUI [1,1])
C0229089 (UMLS CUI [1,2])
C0681850 (UMLS CUI [2,1])
C0444868 (UMLS CUI [2,2])
Code List
SUBRETINAL/SUBRPE HEMORRHAGE FIELD 2 RT EYE (ALL PARTICIPANTS)
CL Item
None (0)
C0549184 (UMLS CUI [1,1])
CL Item
Questionable (1)
C0332241 (UMLS CUI [1,1])
CL Item
Yes (2)
C1705108 (UMLS CUI [1,1])
CL Item
Cannot grade (8)
C1707258 (UMLS CUI [1,1])
Item
SUBRETINAL FIBROSIS FIELD 2 RT EYE (ALL PARTICIPANTS)
text
C0423434 (UMLS CUI [1,1])
C0229089 (UMLS CUI [1,2])
C0681850 (UMLS CUI [2,1])
C0444868 (UMLS CUI [2,2])
Code List
SUBRETINAL FIBROSIS FIELD 2 RT EYE (ALL PARTICIPANTS)
CL Item
None (0)
C0549184 (UMLS CUI [1,1])
CL Item
Questionable (1)
C0332241 (UMLS CUI [1,1])
CL Item
Yes (2)
C1705108 (UMLS CUI [1,1])
CL Item
Cannot grade (8)
C1707258 (UMLS CUI [1,1])
Item
PC/AMD FIELD 2 RT EYE (ALL PARTICIPANTS)
text
C0242383 (UMLS CUI [1,1])
C0042826 (UMLS CUI [1,2])
C0229089 (UMLS CUI [1,3])
C0681850 (UMLS CUI [2,1])
C0444868 (UMLS CUI [2,2])
Code List
PC/AMD FIELD 2 RT EYE (ALL PARTICIPANTS)
CL Item
None (0)
C0549184 (UMLS CUI [1,1])
CL Item
Questionable (1)
C0332241 (UMLS CUI [1,1])
CL Item
Yes (2)
C1705108 (UMLS CUI [1,1])
CL Item
Cannot grade (8)
C1707258 (UMLS CUI [1,1])
Item
GEOGRAPHIC ATROPHY CENTER POINT RT EYE (ALL PARTICIPANTS)
text
C1536085 (UMLS CUI [1,1])
C0205099 (UMLS CUI [1,2])
C0229089 (UMLS CUI [1,3])
C0681850 (UMLS CUI [2,1])
C0444868 (UMLS CUI [2,2])
Code List
GEOGRAPHIC ATROPHY CENTER POINT RT EYE (ALL PARTICIPANTS)
CL Item
None (0)
C0549184 (UMLS CUI [1,1])
CL Item
Questionable (1)
C0332241 (UMLS CUI [1,1])
CL Item
Definite, <Circle I2 (diameter, 0.241 DD; area, 0.058 DA) (2)
C0439544 (UMLS CUI [1,1])
CL Item
Cannot grade (8)
C1707258 (UMLS CUI [1,1])
Item
GEOGRAPHIC ATROPHY AREA C/SUB RT EYE (ALL PARTICIPANTS)
text
C1536085 (UMLS CUI [1,1])
C0205146 (UMLS CUI [1,2])
C0229089 (UMLS CUI [1,3])
C0681850 (UMLS CUI [2,1])
C0444868 (UMLS CUI [2,2])
Code List
GEOGRAPHIC ATROPHY AREA C/SUB RT EYE (ALL PARTICIPANTS)
CL Item
None (0)
C0549184 (UMLS CUI [1,1])
CL Item
Questionable (1)
C0332241 (UMLS CUI [1,1])
CL Item
Definite, less than Circle I2 (diameter, 0.241 DD; area, 0.058 DA) (2)
C0439544 (UMLS CUI [1,1])
CL Item
Definite, more than or equal to Circle I2 (diameter, 0.241 DD; area, 0.058 DA), less than Circle O2 (diameter, 0.439 DD; area, 0.19 DA) (3)
C0439544 (UMLS CUI [1,1])
CL Item
Definite, more than or equal to Circle O2 (diameter, 0.439 DD; area, 0.19 DA), less than 0.5 DA in area (diameter, 0.707 DD) (4)
C0439544 (UMLS CUI [1,1])
CL Item
Cannot Grade (8)
C1707258 (UMLS CUI [1,1])
Item
GEOGRAPHIC ATROPHY W/I GRID RT EYE (ALL PARTICIPANTS)
text
C1536085 (UMLS CUI [1,1])
C0229089 (UMLS CUI [1,2])
C0491832 (UMLS CUI [1,3])
C0681850 (UMLS CUI [2,1])
C0444868 (UMLS CUI [2,2])
Code List
GEOGRAPHIC ATROPHY W/I GRID RT EYE (ALL PARTICIPANTS)
CL Item
None (0)
C0549184 (UMLS CUI [1,1])
CL Item
Questionable (1)
C0332241 (UMLS CUI [1,1])
CL Item
Definite, less than Circle I2 (diameter, 0.241 DD; area, 0.058 DA) (2)
C0439544 (UMLS CUI [1,1])
CL Item
Definite, more than or equal to Circle I2 (diameter, 0.241 DD; area, 0.058 DA), less than Circle O2 (diameter, 0.439 DD; area, 0.19 DA) (3)
C0439544 (UMLS CUI [1,1])
CL Item
Definite, more than or equal to Circle O2 (diameter, 0.439 DD; area, 0.19 DA), less than 0.5 DA in area (diameter, 0.707 DD) (4)
C0439544 (UMLS CUI [1,1])
CL Item
Cannot Grade (8)
C1707258 (UMLS CUI [1,1])
Item
RPE DEPIGMENTATION AREA C/SUB+INNERS RT EYE (ALL PARTICIPANTS)
text
C0151891 (UMLS CUI [1,1])
C0205146 (UMLS CUI [1,2])
C0229089 (UMLS CUI [1,3])
C0681850 (UMLS CUI [2,1])
C0444868 (UMLS CUI [2,2])
Code List
RPE DEPIGMENTATION AREA C/SUB+INNERS RT EYE (ALL PARTICIPANTS)
CL Item
None (0)
C0549184 (UMLS CUI [1,1])
CL Item
Questionable (1)
C0332241 (UMLS CUI [1,1])
CL Item
Definite, less than Circle I2 (diameter, 0.241 DD; area, 0.058 DA) (2)
C0439544 (UMLS CUI [1,1])
CL Item
Definite, more than or equal to Circle I2 (diameter, 0.241 DD; area, 0.058 DA), less than Circle O2 (diameter, 0.439 DD; area, 0.19 DA) (3)
C0439544 (UMLS CUI [1,1])
CL Item
Definite, more than or equal to Circle O2 (diameter, 0.439 DD; area, 0.19 DA), less than 0.5 DA in area (diameter, 0.707 DD) (4)
C0439544 (UMLS CUI [1,1])
CL Item
Cannot Grade (8)
C1707258 (UMLS CUI [1,1])
Item
RPE DEPIGMENTATION AREA W/I GRID RT EYE (ALL PARTICIPANTS)
text
C0229089 (UMLS CUI [1,1])
C0151891 (UMLS CUI [1,2])
C0205146 (UMLS CUI [1,3])
C0681850 (UMLS CUI [2,1])
C0444868 (UMLS CUI [2,2])
Code List
RPE DEPIGMENTATION AREA W/I GRID RT EYE (ALL PARTICIPANTS)
CL Item
None (0)
C0549184 (UMLS CUI [1,1])
CL Item
Questionable (1)
C0332241 (UMLS CUI [1,1])
CL Item
Definite, less than Circle I2 (diameter, 0.241 DD; area, 0.058 DA) (2)
C0439544 (UMLS CUI [1,1])
CL Item
Definite, more than or equal to Circle I2 (diameter, 0.241 DD; area, 0.058 DA), less than Circle O2 (diameter, 0.439 DD; area, 0.19 DA) (3)
C0439544 (UMLS CUI [1,1])
CL Item
Definite, more than or equal to Circle O2 (diameter, 0.439 DD; area, 0.19 DA), less than 0.5 DA in area (diameter, 0.707 DD) (4)
C0439544 (UMLS CUI [1,1])
CL Item
Cannot Grade (8)
C1707258 (UMLS CUI [1,1])
Item
INCREASED PIGMENT AREA C/SUB+INNERS RT EYE (ALL PARTICIPANTS)
text
C3163633 (UMLS CUI [1,1])
C0031916 (UMLS CUI [1,2])
C0205146 (UMLS CUI [1,3])
C0681850 (UMLS CUI [2,1])
C0444868 (UMLS CUI [2,2])
Code List
INCREASED PIGMENT AREA C/SUB+INNERS RT EYE (ALL PARTICIPANTS)
CL Item
None (0)
C0549184 (UMLS CUI [1,1])
CL Item
Questionable (1)
C0332241 (UMLS CUI [1,1])
CL Item
Definite, less than Circle C0 (diameter, 0.042 DD; area, 0.0017 DA) (2)
C0439544 (UMLS CUI [1,1])
CL Item
Definite, more than or equal to Circle C0 (diameter, 0.042 DD; area, 0.0017 DA), less than Circle C1 (diameter, 0.083 DD; area, 0.0069 DA) (3)
C0439544 (UMLS CUI [1,1])
CL Item
Definite, more than or equal to Circle C1 (diameter, 0.083 DD; area, 0.0069 DA), less than Circle C2 (diameter, 0.167 DD; area, 0.028 DA) (4)
C0439544 (UMLS CUI [1,1])
CL Item
Definite, more than or equal to Circle C2 (diameter, 0.167 DD; area, 0.028 DA), less than Circle O2 (diameter, 0.439 DD; area, 0.19 DA) (5)
C0439544 (UMLS CUI [1,1])
CL Item
Definite, more than or equal to Circle O2 (diameter, 0.439 DD; area, 0.19 DA) (6)
CL Item
Other (7)
C0205394 (UMLS CUI [1,1])
CL Item
Cannot Grade (8)
C1707258 (UMLS CUI [1,1])
Item
INCREASED PIGMENT AREA W/I GRID RT EYE (ALL PARTICIPANTS)
text
C3163633 (UMLS CUI [1,1])
C0031916 (UMLS CUI [1,2])
C0205146 (UMLS CUI [1,3])
C0430942 (UMLS CUI [1,4])
C0229089 (UMLS CUI [1,5])
C0681850 (UMLS CUI [2,1])
C0444868 (UMLS CUI [2,2])
Code List
INCREASED PIGMENT AREA W/I GRID RT EYE (ALL PARTICIPANTS)
CL Item
None (0)
C0549184 (UMLS CUI [1,1])
CL Item
Questionable (1)
C0332241 (UMLS CUI [1,1])
CL Item
Definite, less than Circle C0 (diameter, 0.042 DD; area, 0.0017 DA) (2)
C0439544 (UMLS CUI [1,1])
CL Item
Definite, more than or equal to Circle C0 (diameter, 0.042 DD; area, 0.0017 DA), less than Circle C1 (diameter, 0.083 DD; area, 0.0069 DA) (3)
C0439544 (UMLS CUI [1,1])
CL Item
Definite, more than or equal to Circle C1 (diameter, 0.083 DD; area, 0.0069 DA), less than Circle C2 (diameter, 0.167 DD; area, 0.028 DA) (4)
C0439544 (UMLS CUI [1,1])
CL Item
Definite, more than or equal to Circle C2 (diameter, 0.167 DD; area, 0.028 DA), less than Circle O2 (diameter, 0.439 DD; area, 0.19 DA) (5)
C0439544 (UMLS CUI [1,1])
CL Item
Definite, more than or equal to Circle O2 (diameter, 0.439 DD; area, 0.19 DA) (6)
CL Item
Other (7)
C0205394 (UMLS CUI [1,1])
CL Item
Cannot Grade (8)
C1707258 (UMLS CUI [1,1])
Item
MAXIMUM DRUSEN SIZE W/I GRID RT EYE (ALL PARTICIPANTS)
text
C0806909 (UMLS CUI [1,1])
C1260959 (UMLS CUI [1,2])
C0456389 (UMLS CUI [1,3])
C0430942 (UMLS CUI [1,4])
C0229089 (UMLS CUI [1,5])
C0681850 (UMLS CUI [2,1])
C0444868 (UMLS CUI [2,2])
Code List
MAXIMUM DRUSEN SIZE W/I GRID RT EYE (ALL PARTICIPANTS)
CL Item
None (0)
C0549184 (UMLS CUI [1,1])
CL Item
Questionable (1)
C0332241 (UMLS CUI [1,1])
CL Item
Definite, less than Circle C0 (63 microns) (2)
C0439544 (UMLS CUI [1,1])
CL Item
Definite, more than or equal to Circle C0 (63 microns), less than Circle C1 (125 microns) (3)
C0439544 (UMLS CUI [1,1])
CL Item
Definite, more than or equal to Circle C1 (125 microns), less than Circle C2 (250 microns) (4)
C0439544 (UMLS CUI [1,1])
CL Item
Definite, more than or equal to Circle C2 (250 microns) (5)
C0439544 (UMLS CUI [1,1])
CL Item
Cannot grade (8)
C1707258 (UMLS CUI [1,1])
Item
SOFT DRUSEN RT EYE (ALL PARTICIPANTS)
text
C0229089 (UMLS CUI [1,1])
C0205358 (UMLS CUI [1,2])
C1260959 (UMLS CUI [1,3])
C0681850 (UMLS CUI [2,1])
C0444868 (UMLS CUI [2,2])
Code List
SOFT DRUSEN RT EYE (ALL PARTICIPANTS)
CL Item
None (0)
C0549184 (UMLS CUI [1,1])
CL Item
Soft distinct (1)
C0205358 (UMLS CUI [1,1])
C1705242 (UMLS CUI [1,2])
CL Item
Soft indistinct (2)
C0205358 (UMLS CUI [1,1])
CL Item
Cannot grade (8)
C1707258 (UMLS CUI [1,1])
Item
DRUSEN AREA W/I GRID (ALL PARTICIPANTS)
text
C0035312 (UMLS CUI [1,1])
C0205146 (UMLS CUI [1,2])
C0491832 (UMLS CUI [1,3])
C0681850 (UMLS CUI [2,1])
C0444868 (UMLS CUI [2,2])
Code List
DRUSEN AREA W/I GRID (ALL PARTICIPANTS)
CL Item
None/Questionable/less than Circle C0 (diameter, 0.042 DD; area, 0.0017 DA) (0)
C0549184 (UMLS CUI [1,1])
C0332241 (UMLS CUI [1,2])
C0439092 (UMLS CUI [1,3])
CL Item
Definite, more than or equal to Circle C0 (diameter, 0.042 DD; area, 0.0017 DA), less than Circle C1 (diameter, 0.083 DD;area, 0.0069 DA) (1)
C0439544 (UMLS CUI [1,1])
CL Item
Definite, more than or equal to Circle C1 (diameter, 0.083 DD;area, 0.0069 DA), less than Circle C2 (diameter, 0.167 DD;area, 0.028 DA) (2)
C0439544 (UMLS CUI [1,1])
CL Item
Definite, more than or equal to Circle C2 (diameter, 0.167 DD;area, 0.028 DA), less than Circle I2 (diameter, 0.241 DD;area, 0.058 DA) (3)
C0439544 (UMLS CUI [1,1])
CL Item
Definite, more than or equal to Circle I2 (diameter, 0.241 DD;area, 0.058 DA), less than Circle O2 (diameter, 0.439 DD; area, 0.19 DA) (4)
C0439544 (UMLS CUI [1,1])
CL Item
Definite, more than or equal to Circle O2 (diameter, 0.439 DD; area, 0.19 DA), less than 0.5 DA in area (diameter, 0.707 DD) (5)
C0439544 (UMLS CUI [1,1])
CL Item
Definite, more than or equal to 0.5 DA in area (diameter, 0.707 DD), less than 1 DA in area (diameter, 1.0 DD) (6)
C0439544 (UMLS CUI [1,1])
CL Item
Definite, more than or equal to 1.0 DA in area (diameter, 1.0 DD) (7)
C0439544 (UMLS CUI [1,1])
CL Item
Cannot Grade (8)
C1707258 (UMLS CUI [1,1])
CL Item
End Stage (9)
C0444930 (UMLS CUI [1,1])
C1306673 (UMLS CUI [1,2])
Item
RETICULAR DRUSEN RT EYE (ALL PARTICIPANTS)
text
C1260959 (UMLS CUI [1,1])
C0229089 (UMLS CUI [1,2])
C0681850 (UMLS CUI [2,1])
C0444868 (UMLS CUI [2,2])
Code List
RETICULAR DRUSEN RT EYE (ALL PARTICIPANTS)
CL Item
None (0)
C0549184 (UMLS CUI [1,1])
CL Item
Questionable (1)
C0332241 (UMLS CUI [1,1])
CL Item
Outside grid (2)
C0430942 (UMLS CUI [1,1])
CL Item
W/I grid +/- outside grid (3)
C0430942 (UMLS CUI [1,1])
CL Item
Cannot grade (8)
C1707258 (UMLS CUI [1,1])
Item
CALCIFIED DRUSEN W/I OR OUTSIDE GRID RT EYE (ALL PARTICIPANTS)
text
C0229089 (UMLS CUI [1,1])
C0175895 (UMLS CUI [1,2])
C1260959 (UMLS CUI [1,3])
C0491832 (UMLS CUI [1,4])
C0681850 (UMLS CUI [2,1])
C0444868 (UMLS CUI [2,2])
Code List
CALCIFIED DRUSEN W/I OR OUTSIDE GRID RT EYE (ALL PARTICIPANTS)
CL Item
None (0)
C0549184 (UMLS CUI [1,1])
CL Item
Questionable (1)
C0332241 (UMLS CUI [1,1])
CL Item
Yes (2)
C1705108 (UMLS CUI [1,1])
CL Item
Cannot grade (8)
C1707258 (UMLS CUI [1,1])
Item
DRUSEN CATEGORY RT EYE (ALL PARTICIPANTS)
text
C1260959 (UMLS CUI [1,1])
C0683312 (UMLS CUI [1,2])
C0229089 (UMLS CUI [1,3])
C0681850 (UMLS CUI [2,1])
C0444868 (UMLS CUI [2,2])
Code List
DRUSEN CATEGORY RT EYE (ALL PARTICIPANTS)
CL Item
Category 1 (1)
C0683312 (UMLS CUI [1,1])
CL Item
Category 2 (2)
C0683312 (UMLS CUI [1,1])
CL Item
Category 3 (3)
C0683312 (UMLS CUI [1,1])
CL Item
Category 4 (4)
C0683312 (UMLS CUI [1,1])
CL Item
Disqualifying lesion (visno=00 only) (5)
C0221198 (UMLS CUI [1,1])
C1709790 (UMLS CUI [1,2])
C1298908 (UMLS CUI [1,3])
CL Item
Cannot grade (8)
C1707258 (UMLS CUI [1,1])
Item
DRUSENOID PED FIELD 2 LT EYE (ALL PARTICIPANTS)
text
C0229090 (UMLS CUI [1,1])
C1260959 (UMLS CUI [1,2])
C0339546 (UMLS CUI [1,3])
C0042826 (UMLS CUI [1,4])
C0681850 (UMLS CUI [2,1])
C0444868 (UMLS CUI [2,2])
Code List
DRUSENOID PED FIELD 2 LT EYE (ALL PARTICIPANTS)
CL Item
None (0)
C0549184 (UMLS CUI [1,1])
CL Item
Questionable (1)
C0332241 (UMLS CUI [1,1])
CL Item
Yes (2)
C1705108 (UMLS CUI [1,1])
CL Item
Cannot grade (8)
C1707258 (UMLS CUI [1,1])
Item
NON-DRUSENOID PED FIELD 2 LT EYE (ALL PARTICIPANTS)
text
C0229090 (UMLS CUI [1,1])
C1298908 (UMLS CUI [1,2])
C1260959 (UMLS CUI [1,3])
C0339546 (UMLS CUI [1,4])
C0042826 (UMLS CUI [1,5])
C0681850 (UMLS CUI [2,1])
C0444868 (UMLS CUI [2,2])
Code List
NON-DRUSENOID PED FIELD 2 LT EYE (ALL PARTICIPANTS)
CL Item
None (0)
C0549184 (UMLS CUI [1,1])
CL Item
Questionable (1)
C0332241 (UMLS CUI [1,1])
CL Item
Yes (2)
C1705108 (UMLS CUI [1,1])
CL Item
Cannot grade (8)
C1707258 (UMLS CUI [1,1])
Item
SSR/HEMORRHAGIC RD FIELD 2 LT EYE (ALL PARTICIPANTS)
text
C0035305 (UMLS CUI [1,1])
C0035317 (UMLS CUI [1,2])
C0229089 (UMLS CUI [1,3])
C0681850 (UMLS CUI [2,1])
C0444868 (UMLS CUI [2,2])
Code List
SSR/HEMORRHAGIC RD FIELD 2 LT EYE (ALL PARTICIPANTS)
CL Item
None (0)
CL Item
Questionable (1)
CL Item
Yes (2)
CL Item
Cannot grade (8)
Item
HARD EXUDATE FIELD 2 LT EYE (ALL PARTICIPANTS)
text
C0229090 (UMLS CUI [1,1])
C0018599 (UMLS CUI [1,2])
C0015388 (UMLS CUI [1,3])
C0042826 (UMLS CUI [1,4])
C0681850 (UMLS CUI [2,1])
C0444868 (UMLS CUI [2,2])
Code List
HARD EXUDATE FIELD 2 LT EYE (ALL PARTICIPANTS)
CL Item
None (0)
C0549184 (UMLS CUI [1,1])
CL Item
Questionable (1)
C0332241 (UMLS CUI [1,1])
CL Item
Yes (2)
C1705108 (UMLS CUI [1,1])
CL Item
Cannot grade (8)
C1707258 (UMLS CUI [1,1])
Item
SUBRETINAL/SUBRPE HEMORRHAGE FIELD 2 LT EYE (ALL PARTICIPANTS)
text
C0019080 (UMLS CUI [1,1])
C0229090 (UMLS CUI [1,2])
C2699708 (UMLS CUI [1,3])
C0042826 (UMLS CUI [1,4])
C0681850 (UMLS CUI [2,1])
C0444868 (UMLS CUI [2,2])
Code List
SUBRETINAL/SUBRPE HEMORRHAGE FIELD 2 LT EYE (ALL PARTICIPANTS)
CL Item
None (0)
C0549184 (UMLS CUI [1,1])
CL Item
Questionable (1)
C0332241 (UMLS CUI [1,1])
CL Item
Yes (2)
C1705108 (UMLS CUI [1,1])
CL Item
Cannot grade (8)
C1707258 (UMLS CUI [1,1])
Item
SUBRETINAL FIBROSIS FIELD 2 LT EYE (ALL PARTICIPANTS)
text
C0229090 (UMLS CUI [1,1])
C2699708 (UMLS CUI [1,2])
C0016059 (UMLS CUI [1,3])
C0681850 (UMLS CUI [2,1])
C0444868 (UMLS CUI [2,2])
Code List
SUBRETINAL FIBROSIS FIELD 2 LT EYE (ALL PARTICIPANTS)
CL Item
None (0)
C0549184 (UMLS CUI [1,1])
CL Item
Questionable (1)
C0332241 (UMLS CUI [1,1])
CL Item
Yes (2)
C1705108 (UMLS CUI [1,1])
CL Item
Cannot grade (8)
C1707258 (UMLS CUI [1,1])
Item
PC/AMD FIELD 2 LT EYE (ALL PARTICIPANTS)
text
C0242383 (UMLS CUI [1,1])
C0042826 (UMLS CUI [1,2])
C0229090 (UMLS CUI [1,3])
C0681850 (UMLS CUI [2,1])
C0444868 (UMLS CUI [2,2])
Code List
PC/AMD FIELD 2 LT EYE (ALL PARTICIPANTS)
CL Item
None (0)
C0549184 (UMLS CUI [1,1])
CL Item
Questionable (1)
C0332241 (UMLS CUI [1,1])
CL Item
Yes (2)
C1705108 (UMLS CUI [1,1])
CL Item
Cannot grade (8)
C1707258 (UMLS CUI [1,1])
Item
GEOGRAPHIC ATROPHY CENTER POINT LT EYE (ALL PARTICIPANTS)
text
C1536085 (UMLS CUI [1,1])
C0205099 (UMLS CUI [1,2])
C0229090 (UMLS CUI [1,3])
C0681850 (UMLS CUI [2,1])
C0444868 (UMLS CUI [2,2])
Code List
GEOGRAPHIC ATROPHY CENTER POINT LT EYE (ALL PARTICIPANTS)
CL Item
None (0)
C0549184 (UMLS CUI [1,1])
CL Item
Questionable (1)
C0332241 (UMLS CUI [1,1])
CL Item
Definite, <Circle I2 (diameter, 0.241 DD; area, 0.058 DA) (2)
C0439544 (UMLS CUI [1,1])
CL Item
Cannot Grade (8)
C1707258 (UMLS CUI [1,1])
Item
GEOGRAPHIC ATROPHY AREA C/SUB LT EYE (ALL PARTICIPANTS)
text
C1536085 (UMLS CUI [1,1])
C0205099 (UMLS CUI [1,2])
C0229090 (UMLS CUI [1,3])
C0681850 (UMLS CUI [2,1])
C0444868 (UMLS CUI [2,2])
Code List
GEOGRAPHIC ATROPHY AREA C/SUB LT EYE (ALL PARTICIPANTS)
CL Item
None (0)
C0549184 (UMLS CUI [1,1])
CL Item
Questionable (1)
C0332241 (UMLS CUI [1,1])
CL Item
Definite, less than Circle I2 (diameter, 0.241 DD; area, 0.058 DA) (2)
C0439544 (UMLS CUI [1,1])
CL Item
Definite, more than or equal to Circle I2 (diameter, 0.241 DD; area, 0.058 DA), less than Circle O2 (diameter, 0.439 DD; area, 0.19 DA) (3)
C0439544 (UMLS CUI [1,1])
CL Item
Definite, more than or equal to Circle O2 (diameter, 0.439 DD; area, 0.19 DA), less than 0.5 DA in area (diameter, 0.707 DD) (4)
C0439544 (UMLS CUI [1,1])
CL Item
Cannot Grade (8)
C1707258 (UMLS CUI [1,1])
Item
GEOGRAPHIC ATROPHY W/I GRID LT EYE (ALL PARTICIPANTS)
text
C1536085 (UMLS CUI [1,1])
C0205099 (UMLS CUI [1,2])
C0229090 (UMLS CUI [1,3])
C0681850 (UMLS CUI [2,1])
C0444868 (UMLS CUI [2,2])
Code List
GEOGRAPHIC ATROPHY W/I GRID LT EYE (ALL PARTICIPANTS)
CL Item
None (0)
C0549184 (UMLS CUI [1,1])
CL Item
Questionable (1)
C0332241 (UMLS CUI [1,1])
CL Item
Definite, less than Circle I2 (diameter, 0.241 DD; area, 0.058 DA) (2)
C0439544 (UMLS CUI [1,1])
CL Item
Definite, more than or equal to Circle I2 (diameter, 0.241 DD; area, 0.058 DA), less than Circle O2 (diameter, 0.439 DD; area, 0.19 DA) (3)
C0439544 (UMLS CUI [1,1])
CL Item
Definite, more than or equal to Circle O2 (diameter, 0.439 DD; area, 0.19 DA), less than 0.5 DA in area (diameter, 0.707 DD) (4)
C0439544 (UMLS CUI [1,1])
CL Item
Cannot Grade (8)
C1707258 (UMLS CUI [1,1])
Item
RPE DEPIGMENTATION AREA C/SUB+INNERS LT EYE (ALL PARTICIPANTS)
text
C0151891 (UMLS CUI [1,1])
C0205146 (UMLS CUI [1,2])
C0229090 (UMLS CUI [1,3])
C0681850 (UMLS CUI [2,1])
C0444868 (UMLS CUI [2,2])
Code List
RPE DEPIGMENTATION AREA C/SUB+INNERS LT EYE (ALL PARTICIPANTS)
CL Item
None (0)
C0549184 (UMLS CUI [1,1])
CL Item
Questionable (1)
C0332241 (UMLS CUI [1,1])
CL Item
Definite, less than Circle I2 (diameter, 0.241 DD; area, 0.058 DA) (2)
C0439544 (UMLS CUI [1,1])
CL Item
Definite, more than or equal to Circle I2 (diameter, 0.241 DD; area, 0.058 DA), less than Circle O2 (diameter, 0.439 DD; area, 0.19 DA) (3)
C0439544 (UMLS CUI [1,1])
CL Item
Definite, more than or equal to Circle O2 (diameter, 0.439 DD; area, 0.19 DA), less than 0.5 DA in area (diameter, 0.707 DD) (4)
C0439544 (UMLS CUI [1,1])
CL Item
Cannot Grade (8)
C1707258 (UMLS CUI [1,1])
Item
RPE DEPIGMENTATION AREA W/I GRID LT EYE (ALL PARTICIPANTS)
text
C0151891 (UMLS CUI [1,1])
C0205146 (UMLS CUI [1,2])
C0229090 (UMLS CUI [1,3])
C0681850 (UMLS CUI [2,1])
C0444868 (UMLS CUI [2,2])
Code List
RPE DEPIGMENTATION AREA W/I GRID LT EYE (ALL PARTICIPANTS)
CL Item
None (0)
C0549184 (UMLS CUI [1,1])
CL Item
Questionable (1)
C0332241 (UMLS CUI [1,1])
CL Item
Definite, less than Circle I2 (diameter, 0.241 DD; area, 0.058 DA) (2)
C0439544 (UMLS CUI [1,1])
CL Item
Definite, more than or equal to Circle I2 (diameter, 0.241 DD; area, 0.058 DA), less than Circle O2 (diameter, 0.439 DD; area, 0.19 DA) (3)
C0439544 (UMLS CUI [1,1])
CL Item
Definite, more than or equal to Circle O2 (diameter, 0.439 DD; area, 0.19 DA), less than 0.5 DA in area (diameter, 0.707 DD) (4)
C0439544 (UMLS CUI [1,1])
CL Item
Cannot Grade (8)
C1707258 (UMLS CUI [1,1])
Item
INCREASED PIGMENT AREA C/SUB+INNERS LT EYE (ALL PARTICIPANTS)
text
C3163633 (UMLS CUI [1,1])
C0031916 (UMLS CUI [1,2])
C0205146 (UMLS CUI [1,3])
C0229090 (UMLS CUI [1,4])
C0681850 (UMLS CUI [2,1])
C0444868 (UMLS CUI [2,2])
Code List
INCREASED PIGMENT AREA C/SUB+INNERS LT EYE (ALL PARTICIPANTS)
CL Item
None (0)
C0549184 (UMLS CUI [1,1])
CL Item
Questionable (1)
C0332241 (UMLS CUI [1,1])
CL Item
Definite, less than Circle C0 (diameter, 0.042 DD; area, 0.0017 DA) (2)
C0439544 (UMLS CUI [1,1])
CL Item
Definite, more than or equal to Circle C0 (diameter, 0.042 DD; area, 0.0017 DA), less than Circle C1 (diameter, 0.083 DD; area, 0.0069 DA) (3)
C0439544 (UMLS CUI [1,1])
CL Item
Definite, more than or equal to Circle C1 (diameter, 0.083 DD; area, 0.0069 DA), less than Circle C2 (diameter, 0.167 DD; area, 0.028 DA) (4)
C0439544 (UMLS CUI [1,1])
CL Item
Definite, more than or equal to Circle C2 (diameter, 0.167 DD; area, 0.028 DA), less than Circle O2 (diameter, 0.439 DD; area, 0.19 DA) (5)
C0439544 (UMLS CUI [1,1])
CL Item
Definite, more than or equal to Circle O2 (diameter, 0.439 DD; area, 0.19 DA) (6)
CL Item
Other (7)
C0205394 (UMLS CUI [1,1])
CL Item
Cannot Grade (8)
C1707258 (UMLS CUI [1,1])
Item
INCREASED PIGMENT AREA W/I GRID LT EYE (ALL PARTICIPANTS)
text
C3163633 (UMLS CUI [1,1])
C0031916 (UMLS CUI [1,2])
C0205146 (UMLS CUI [1,3])
C0229090 (UMLS CUI [1,4])
C0681850 (UMLS CUI [2,1])
C0444868 (UMLS CUI [2,2])
Code List
INCREASED PIGMENT AREA W/I GRID LT EYE (ALL PARTICIPANTS)
CL Item
None (0)
C0549184 (UMLS CUI [1,1])
CL Item
Questionable (1)
C0332241 (UMLS CUI [1,1])
CL Item
Definite, less than Circle C0 (diameter, 0.042 DD; area, 0.0017 DA) (2)
C0439544 (UMLS CUI [1,1])
CL Item
Definite, more than or equal to Circle C0 (diameter, 0.042 DD; area, 0.0017 DA), less than Circle C1 (diameter, 0.083 DD; area, 0.0069 DA) (3)
C0439544 (UMLS CUI [1,1])
CL Item
Definite, more than or equal to Circle C1 (diameter, 0.083 DD; area, 0.0069 DA), less than Circle C2 (diameter, 0.167 DD; area, 0.028 DA) (4)
C0439544 (UMLS CUI [1,1])
CL Item
Definite, more than or equal to Circle C2 (diameter, 0.167 DD; area, 0.028 DA), less than Circle O2 (diameter, 0.439 DD; area, 0.19 DA) (5)
C0439544 (UMLS CUI [1,1])
CL Item
Definite, more than or equal to Circle O2 (diameter, 0.439 DD; area, 0.19 DA) (6)
CL Item
Other (7)
C0205394 (UMLS CUI [1,1])
CL Item
Cannot Grade (8)
C1707258 (UMLS CUI [1,1])
Item
MAXIMUM DRUSEN SIZE W/I GRID LT EYE (ALL PARTICIPANTS)
text
C0806909 (UMLS CUI [1,1])
C1260959 (UMLS CUI [1,2])
C0456389 (UMLS CUI [1,3])
C0430942 (UMLS CUI [1,4])
C0229090 (UMLS CUI [1,5])
C0681850 (UMLS CUI [2,1])
C0444868 (UMLS CUI [2,2])
Code List
MAXIMUM DRUSEN SIZE W/I GRID LT EYE (ALL PARTICIPANTS)
CL Item
None (0)
C0549184 (UMLS CUI [1,1])
CL Item
Questionable (1)
C0332241 (UMLS CUI [1,1])
CL Item
Definite, less than Circle C0 (63 microns) (2)
C0439544 (UMLS CUI [1,1])
CL Item
Definite, more than or equal to Circle C0 (63 microns), less than Circle C1 (125 microns) (3)
C0439544 (UMLS CUI [1,1])
CL Item
Definite, more than or equal to Circle C1 (125 microns), less than Circle C2 (250 microns) (4)
C0439544 (UMLS CUI [1,1])
CL Item
Definite, more than or equal to Circle C2 (250 microns) (5)
C0439544 (UMLS CUI [1,1])
CL Item
Cannot grade (8)
C1707258 (UMLS CUI [1,1])
Item
SOFT DRUSEN LT EYE (ALL PARTICIPANTS)
text
C0205358 (UMLS CUI [1,1])
C1260959 (UMLS CUI [1,2])
C0229090 (UMLS CUI [1,3])
C0681850 (UMLS CUI [2,1])
C0444868 (UMLS CUI [2,2])
Code List
SOFT DRUSEN LT EYE (ALL PARTICIPANTS)
CL Item
None (0)
C0549184 (UMLS CUI [1,1])
CL Item
Soft distinct (1)
C0205358 (UMLS CUI [1,1])
C1705242 (UMLS CUI [1,2])
CL Item
Soft indistinct (2)
C0205358 (UMLS CUI [1,1])
CL Item
Cannot grade (8)
C1707258 (UMLS CUI [1,1])
Item
DRUSEN AREA W/I GRID LT EYE (ALL PARTICIPANTS)
text
C0035312 (UMLS CUI [1,1])
C0205146 (UMLS CUI [1,2])
C0491832 (UMLS CUI [1,3])
C0229090 (UMLS CUI [1,4])
C0681850 (UMLS CUI [2,1])
C0444868 (UMLS CUI [2,2])
Code List
DRUSEN AREA W/I GRID LT EYE (ALL PARTICIPANTS)
CL Item
None/Questionable/less than Circle C0 (diameter, 0.042 DD; area, 0.0017 DA) (0)
C0549184 (UMLS CUI [1,1])
C0332241 (UMLS CUI [1,2])
C0439092 (UMLS CUI [1,3])
CL Item
Definite, more than or equal to Circle C0 (diameter, 0.042 DD; area, 0.0017 DA), less than Circle C1 (diameter, 0.083 DD;area, 0.0069 DA) (1)
C0439544 (UMLS CUI [1,1])
CL Item
Definite, more than or equal to Circle C1 (diameter, 0.083 DD;area, 0.0069 DA), less than Circle C2 (diameter, 0.167 DD;area, 0.028 DA) (2)
C0439544 (UMLS CUI [1,1])
CL Item
Definite, more than or equal to Circle C2 (diameter, 0.167 DD;area, 0.028 DA), less than Circle I2 (diameter, 0.241 DD;area, 0.058 DA) (3)
C0439544 (UMLS CUI [1,1])
CL Item
Definite, more than or equal to Circle I2 (diameter, 0.241 DD;area, 0.058 DA), less than Circle O2 (diameter, 0.439 DD; area, 0.19 DA) (4)
C0439544 (UMLS CUI [1,1])
CL Item
Definite, more than or equal to Circle O2 (diameter, 0.439 DD; area, 0.19 DA), less than 0.5 DA in area (diameter, 0.707 DD) (5)
C0439544 (UMLS CUI [1,1])
CL Item
Definite, more than or equal to 0.5 DA in area (diameter, 0.707 DD), less than 1 DA in area (diameter, 1.0 DD) (6)
C0439544 (UMLS CUI [1,1])
CL Item
Definite, more than or equal to 1.0 DA in area (diameter, 1.0 DD) (7)
C0439544 (UMLS CUI [1,1])
CL Item
Cannot Grade (8)
C1707258 (UMLS CUI [1,1])
CL Item
End Stage (9)
C0444930 (UMLS CUI [1,1])
C1306673 (UMLS CUI [1,2])
Item
RETICULAR DRUSEN LT EYE (ALL PARTICIPANTS)
text
C1260959 (UMLS CUI [1,1])
C0229090 (UMLS CUI [1,2])
C0681850 (UMLS CUI [2,1])
C0444868 (UMLS CUI [2,2])
Code List
RETICULAR DRUSEN LT EYE (ALL PARTICIPANTS)
CL Item
None (0)
C0549184 (UMLS CUI [1,1])
CL Item
Questionable (1)
C0332241 (UMLS CUI [1,1])
CL Item
Outside grid (2)
C0430942 (UMLS CUI [1,1])
CL Item
W/I grid +/- outside grid (3)
C0430942 (UMLS CUI [1,1])
CL Item
Cannot grade (8)
C1707258 (UMLS CUI [1,1])
Item
CALCIFIED DRUSEN W/I OR OUTSIDE GRID LT EYE (ALL PARTICIPANTS)
text
C0175895 (UMLS CUI [1,1])
C1260959 (UMLS CUI [1,2])
C0491832 (UMLS CUI [1,3])
C0229090 (UMLS CUI [1,4])
C0681850 (UMLS CUI [2,1])
C0444868 (UMLS CUI [2,2])
Code List
CALCIFIED DRUSEN W/I OR OUTSIDE GRID LT EYE (ALL PARTICIPANTS)
CL Item
None (0)
C0549184 (UMLS CUI [1,1])
CL Item
Questionable (1)
C0332241 (UMLS CUI [1,1])
CL Item
Yes (2)
C1705108 (UMLS CUI [1,1])
CL Item
Cannot grade (8)
C1707258 (UMLS CUI [1,1])
Item
DRUSEN CATEGORY LT EYE (ALL PARTICIPANTS)
text
C1260959 (UMLS CUI [1,1])
C0683312 (UMLS CUI [1,2])
C0229090 (UMLS CUI [1,3])
C0681850 (UMLS CUI [2,1])
C0444868 (UMLS CUI [2,2])
Code List
DRUSEN CATEGORY LT EYE (ALL PARTICIPANTS)
CL Item
Category 1 (1)
CL Item
Category 2 (2)
CL Item
Category 3 (3)
CL Item
Category 4 (4)
CL Item
Disqualifying lesion (visno=00 only) (5)
C0221198 (UMLS CUI [1,1])
C0680251 (UMLS CUI [1,2])
CL Item
Cannot grade (8)
C1707258 (UMLS CUI [1,1])
Item
PARTICIPANT DRUSEN CATEGORY (WORSE EYE; ALL PARTICIPANTS)
text
C0679646 (UMLS CUI [1,1])
C1260959 (UMLS CUI [1,2])
C0683312 (UMLS CUI [1,3])
C0015392 (UMLS CUI [1,4])
C1457868 (UMLS CUI [1,5])
C0681850 (UMLS CUI [2,1])
C0444868 (UMLS CUI [2,2])
Code List
PARTICIPANT DRUSEN CATEGORY (WORSE EYE; ALL PARTICIPANTS)
CL Item
Category 1 (both eyes) (1)
CL Item
Category 2 (2)
CL Item
Category 3 (3)
CL Item
Category 4 (one eye) (4)
CL Item
Category 4 (both eyes) (5)
CL Item
Cannot grade (8)
CL Item
Category 3a (3a)
CL Item
Category 3b (3b)
Item
AMD SEVERITY SCALE SCORE LT EYE (ALL PARTICIPANTS)
text
C0242383 (UMLS CUI [1,1])
C1319166 (UMLS CUI [1,2])
C0681889 (UMLS CUI [1,3])
C0449820 (UMLS CUI [1,4])
C0229090 (UMLS CUI [1,5])
C0681850 (UMLS CUI [2,1])
C0444868 (UMLS CUI [2,2])
Code List
AMD SEVERITY SCALE SCORE LT EYE (ALL PARTICIPANTS)
CL Item
Scale Step 1 (1)
CL Item
Scale Step 2 (2)
CL Item
Scale Step 3 (3)
CL Item
Scale Step 4 (4)
CL Item
Scale Step 5 (5)
CL Item
Scale Step 6 (6)
CL Item
Scale Step 7 (7)
CL Item
Scale Step 8 (8)
CL Item
Scale Step 9 (9)
CL Item
Central Geographic Atrophy (10)
C1536085 (UMLS CUI [1,1])
C0205099 (UMLS CUI [1,2])
CL Item
Neovascular AMD (11)
C0242383 (UMLS CUI [1,1])
C4068891 (UMLS CUI [1,2])
CL Item
Neovascular AMD and Central Geographic Atrophy (12)
C1536085 (UMLS CUI [1,1])
C0205099 (UMLS CUI [1,2])
C0242383 (UMLS CUI [1,3])
C4068891 (UMLS CUI [1,4])
Item
AMD SEVERITY SCALE SCORE RT EYE (ALL PARTICIPANTS)
text
C0242383 (UMLS CUI [1,1])
C1319166 (UMLS CUI [1,2])
C0229089 (UMLS CUI [1,3])
C0681889 (UMLS CUI [1,4])
C0449820 (UMLS CUI [1,5])
C0681850 (UMLS CUI [2,1])
C0444868 (UMLS CUI [2,2])
Code List
AMD SEVERITY SCALE SCORE RT EYE (ALL PARTICIPANTS)
CL Item
Scale Step 1 (1)
CL Item
Scale Step 2 (2)
CL Item
Scale Step 3 (3)
CL Item
Scale Step 4 (4)
CL Item
Scale Step 5 (5)
CL Item
Scale Step 6 (6)
CL Item
Scale Step 7 (7)
CL Item
Scale Step 8 (8)
CL Item
Scale Step 9 (9)
CL Item
Central Geographic Atrophy (10)
C1536085 (UMLS CUI [1,1])
C0205099 (UMLS CUI [1,2])
CL Item
Neovascular AMD (11)
C0242383 (UMLS CUI [1,1])
C4068891 (UMLS CUI [1,2])
CL Item
Neovascular AMD and Central Geographic Atrophy (12)
C1536085 (UMLS CUI [1,1])
C0205099 (UMLS CUI [1,2])
C0242383 (UMLS CUI [1,3])
C4068891 (UMLS CUI [1,4])
SCALE
Item
AMD SIMPLE SCALE SCORE (PERSON; ALL PARTICIPANTS)
text
C0242383 (UMLS CUI [1,1])
C0449820 (UMLS CUI [1,2])
C0681889 (UMLS CUI [1,3])
C0681850 (UMLS CUI [2,1])
C0444868 (UMLS CUI [2,2])
Item
LAST PHOTO IN CLINICAL TRIAL (ALL PARTICIPANTS)
text
C2347804 (UMLS CUI [1,1])
C1517741 (UMLS CUI [1,2])
C0200189 (UMLS CUI [1,3])
C0681850 (UMLS CUI [2,1])
C0444868 (UMLS CUI [2,2])
Code List
LAST PHOTO IN CLINICAL TRIAL (ALL PARTICIPANTS)
CL Item
Yes (Y)
C1705108 (UMLS CUI [1,1])
REPHTIME
Item
YEARS FROM RANDOMIZATION TO DATE OF FUNDUS PHOTO RT EYE (ALL PARTICIPANTS)
float
C0439234 (UMLS CUI [1,1])
C0034656 (UMLS CUI [1,2])
C0200189 (UMLS CUI [1,3])
C0681850 (UMLS CUI [2,1])
C0444868 (UMLS CUI [2,2])
LEPHTIME
Item
YEARS FROM RANDOMIZATION TO DATE OF FUNDUS PHOTO LT EYE (ALL PARTICIPANTS)
float
C0439234 (UMLS CUI [1,1])
C0034656 (UMLS CUI [1,2])
C0200189 (UMLS CUI [1,3])
C0229090 (UMLS CUI [1,4])
C0681850 (UMLS CUI [2,1])
C0444868 (UMLS CUI [2,2])