Sociodemographic data including subject ID, sex, race, study site, study cohort, and age, family history of stroke, systolic and diastolic blood pressure, anthropometric data including BMI, body weight, body height, and waist in centimeters, laboratory measurement of blood including eosinophils, basophils, platelet count, red blood count, neutrophils, monocytes, lymphocytes, hematocrit, hemoglobin, Factor VIII, fasting glucose, fasting insulin, ICAM1 level, IL6 level, cystatin C, Digoxin, total cholesterol, triglycerides, HDL, LDL, C-reactive protein, Factor VII level, and Fibrinogen, uric acid, urinary albumin, and urinary creatinine, EKG including HR, PR, QRS, QT, and RR interval measurement, status of myocardial infraction, angioplasty, atrial fibrillation, atrioventricular block, hypertension, left ventricular hypertrophy, gout, and type 2 diabetes, coronary artery calcium Agatston and Framingham Risk Score, intimal-medial thickness, Wolf-Parkinson-White syndrome, treatment with medications, and smoking status of participants involved in the "National Heart Lung and Blood Institute (NHLBI) GO-ESP: Heart Cohorts Component of the Exome Sequencing Project (ARIC)" project.

4 Formulaires

StudyEvent: SEV1

Name

Type

Description | Question | Decode (Coded Value)

Type de données

Alias

pht002467

Item Group

pht002467

ESP_COHORT

Item

Cohort name

string

C0599755 (UMLS CUI [1,1])
C0027365 (UMLS CUI [1,2])

SUBJID

Item

De-identified subject ID

string

C2348585 (UMLS CUI [1,1])
C4684638 (UMLS CUI [1,2])

ESP_PHENOTYPE

Item

Values: EOMI_Case (Early MI case); EOMI_Control (Early MI control); LDL_High; LDL_Low

string

C0027051 (UMLS CUI [1,1])
C0814120 (UMLS CUI [1,2])
C1698493 (UMLS CUI [1,3])
C0027051 (UMLS CUI [2,1])
C0814120 (UMLS CUI [2,2])
C0009932 (UMLS CUI [2,3])
C4747855 (UMLS CUI [3,1])
C3807409 (UMLS CUI [4,1])

SAMPLE_QC_INFO

Item

Information from quality control analysis

string

C0034378 (UMLS CUI [1,1])

DUP_RELATED_INFO

Item

Information about known duplicates and related

string

C0205309 (UMLS CUI [1,1])
C0205173 (UMLS CUI [1,2])

ESP_RACE

Item

Values: European American; African American

string

C0085756 (UMLS CUI [1,1])
C0043157 (UMLS CUI [2,1])

ESP_SEX

Item

Values: Male; Female

string

C0086582 (UMLS CUI [1,1])
C0086287 (UMLS CUI [2,1])

ESP_STUDY_SITE

Item

Clinic or field center within cohort

string

C0442592 (UMLS CUI [1,1])
C0332285 (UMLS CUI [1,2])
C0599755 (UMLS CUI [1,3])

ESP_AGE_BASELINE

Item

Age in years at baseline

text

C0001779 (UMLS CUI [1,1])
C1442488 (UMLS CUI [1,2])

ESP_MI_BASELINE

Item

MI status at baseline [ 0=No, 1=Yes]

text

C0027051 (UMLS CUI [1,1])
C1442488 (UMLS CUI [1,2])

ESP_MI_BASELINE

Code List

MI status at baseline [ 0=No, 1=Yes]

CL Item

No (0)

CL Item

Yes (1)

ESP_MI_DURING_FOLLOWUP

Item

0/1 - to indicate that an MI occurred during study follow up. 0 - if no MI during study follow up. 1 - if an adjudicated MI occurred during study follow up (even if baseline MI status was 1).

text

C1298908 (UMLS CUI [1,1])
C0027051 (UMLS CUI [1,2])
C0347984 (UMLS CUI [1,3])
C1522577 (UMLS CUI [1,4])
C0027051 (UMLS CUI [2,1])
C0347984 (UMLS CUI [2,2])
C1522577 (UMLS CUI [2,3])

ESP_MI_DURING_FOLLOWUP

Code List

0/1 - to indicate that an MI occurred during study follow up. 0 - if no MI during study follow up. 1 - if an adjudicated MI occurred during study follow up (even if baseline MI status was 1).

CL Item

No (0)

CL Item

Yes (1)

ESP_MI_TTE_OR_CENSOR

Item

Time to event variable for MI. Time (in days) from start of study to MI for event that occurred during study follow up; and follow up time for those that did not have an MI during study follow up.

text

C0040223 (UMLS CUI [1,1])
C1720302 (UMLS CUI [1,2])
C0027051 (UMLS CUI [1,3])
C0347984 (UMLS CUI [1,4])
C1522577 (UMLS CUI [1,5])
C0040223 (UMLS CUI [2,1])
C1522577 (UMLS CUI [2,2])
C1298908 (UMLS CUI [2,3])
C0027051 (UMLS CUI [2,4])

ESP_FRS_CHDPROB_BASELINE

Item

Framingham Risk Score predicted prob. calculated at baseline (was not calculated for those with baseline history of MI)

text

C5442395 (UMLS CUI [1,1])
C1442488 (UMLS CUI [1,2])

ESP_BMI_BASELINE

Item

Baseline BMI in kg/m2

text

C1305855 (UMLS CUI [1,1])
C1442488 (UMLS CUI [1,2])

ESP_T2DIABETES_BASELINE

Item

Type 2 diabetes status at baseline [ 0=No, 1=Yes]

text

C0011860 (UMLS CUI [1,1])
C1442488 (UMLS CUI [1,2])

ESP_T2DIABETES_BASELINE

Code List

Type 2 diabetes status at baseline [ 0=No, 1=Yes]

CL Item

No (0)

CL Item

Yes (1)

ESP_WEIGHT_BASELINE

Item

Weight in kg. at baseline

text

C0005910 (UMLS CUI [1,1])
C1442488 (UMLS CUI [1,2])

ESP_WAIST_BASELINE

Item

Waist in cm at baseline

text

C0455829 (UMLS CUI [1,1])
C1442488 (UMLS CUI [1,2])

ESP_WHR_BASELINE

Item

Waist to hip ratio at baseline

text

C0205682 (UMLS CUI [1,1])
C1442488 (UMLS CUI [1,2])

ESP_HEIGHT_BASELINE

Item

Standing height in cm at baseline

text

C0005890 (UMLS CUI [1,1])
C1442488 (UMLS CUI [1,2])

ESP_LDL_BASELINE

Item

Baseline calculated LDL in mg/dL (missing where trigs>400)

text

C0428474 (UMLS CUI [1,1])
C1442488 (UMLS CUI [1,2])

ESP_HDL_BASELINE

Item

HDL level in mg/dL at baseline

text

C0428472 (UMLS CUI [1,1])
C1442488 (UMLS CUI [1,2])

ESP_TRIGS_BASELINE

Item

Triglycerides at baseline in mg/dL

text

C0202236 (UMLS CUI [1,1])
C1442488 (UMLS CUI [1,2])

ESP_TOTCHOL_BASELINE

Item

Total cholesterol at baseline in mg/dL

text

C1445957 (UMLS CUI [1,1])
C1442488 (UMLS CUI [1,2])

ESP_LIPID_MED_BASELINE

Item

Any lipid lowering med (statin or other) at baseline

text

C0585943 (UMLS CUI [1,1])
C1442488 (UMLS CUI [1,2])

ESP_LIPID_MED_BASELINE

Code List

Any lipid lowering med (statin or other) at baseline

CL Item

No (0)

CL Item

Yes (1)

ESP_SBP_BASELINE

Item

Systolic blood pressure at baseline (avg. of 2 measurements), in mm Hg

text

C0871470 (UMLS CUI [1,1])
C1442488 (UMLS CUI [1,2])

ESP_DBP_BASELINE

Item

Diastolic blood pressure at baseline (avg. of 2 measurements), in mm Hg

text

C0428883 (UMLS CUI [1,1])
C1442488 (UMLS CUI [1,2])

ESP_HTN_STATUS_BASELINE

Item

Physician diagnosed hypertension status at baseline [ 0=No, 1=Yes]

text

C0020538 (UMLS CUI [1,1])
C1442488 (UMLS CUI [1,2])

ESP_HTN_STATUS_BASELINE

Code List

Physician diagnosed hypertension status at baseline [ 0=No, 1=Yes]

CL Item

No (0)

CL Item

Yes (1)

ESP_HTN_MED_BASELINE

Item

Hypertension med status (any) at baseline [ 0=No, 1=Yes]

text

C0684167 (UMLS CUI [1,1])
C1442488 (UMLS CUI [1,2])

ESP_HTN_MED_BASELINE

Code List

Hypertension med status (any) at baseline [ 0=No, 1=Yes]

CL Item

No (0)

CL Item

Yes (1)

ESP_STROKE_BASELINE

Item

Stroke status at baseline [ 0=No, 1=Yes]

text

C0038454 (UMLS CUI [1,1])
C0449438 (UMLS CUI [1,2])
C1442488 (UMLS CUI [1,3])

ESP_STROKE_BASELINE

Code List

Stroke status at baseline [ 0=No, 1=Yes]

CL Item

No (0)

CL Item

Yes (1)

ESP_STROKE_DURING_FOLLOWUP

Item

0/1 - to indicate that a stroke occurred during study follow up. 0 - if no stroke during study follow up. 1 - if an adjudicated stroke occurred during study follow up (even if baseline stroke status was 1).

text

C1298908 (UMLS CUI [1,1])
C0038454 (UMLS CUI [1,2])
C0347984 (UMLS CUI [1,3])
C1522577 (UMLS CUI [1,4])
C0038454 (UMLS CUI [2,1])
C0347984 (UMLS CUI [2,2])
C1522577 (UMLS CUI [2,3])

ESP_STROKE_DURING_FOLLOWUP

Code List

CL Item

No (0)

CL Item

Yes (1)

ESP_STROKE_TTE_OR_CENSOR

Item

Time to event variable for stroke. Time (in days) from start of study to stroke for event that occurred during study follow up; and follow up time for those that did not have an stroke during study follow up.

text

C0040223 (UMLS CUI [1,1])
C1720302 (UMLS CUI [1,2])
C0038454 (UMLS CUI [1,3])
C1522577 (UMLS CUI [2,1])
C0040223 (UMLS CUI [2,2])
C1298908 (UMLS CUI [2,3])
C0038454 (UMLS CUI [2,4])

ESP_INC_STROKE_SUBTYPE

Item

Incident stroke subtype (Lacune or LVAth). Subtype is available only on a subset of samples, so will be missing for some with non-missing age at incident stroke

text

C0449560 (UMLS CUI [1,1])
C0038454 (UMLS CUI [1,2])

ESP_STROKE_FAMHX_BASELINE

Item

Family history (first degree relatives) of stroke at baseline [ 0=No, 1=Yes]

text

C0241889 (UMLS CUI [1,1])
C0559159 (UMLS CUI [1,2])
C1442488 (UMLS CUI [1,3])

ESP_STROKE_FAMHX_BASELINE

Code List

Family history (first degree relatives) of stroke at baseline [ 0=No, 1=Yes]

CL Item

No (0)

CL Item

Yes (1)

ESP_CURRENT_SMOKER_BASELINE

Item

Current smoking status at baseline [ 0=No, 1=Yes]

text

C0521116 (UMLS CUI [1,1])
C3496610 (UMLS CUI [1,2])
C1442488 (UMLS CUI [1,3])

ESP_CURRENT_SMOKER_BASELINE

Code List

Current smoking status at baseline [ 0=No, 1=Yes]

CL Item

No (0)

CL Item

Yes (1)

ESP_FORMER_SMOKER_BASELINE

Item

Former smoking status at baseline [ 0=No, 1=Yes]

text

C0205156 (UMLS CUI [1,1])
C1519386 (UMLS CUI [1,2])
C1442488 (UMLS CUI [1,3])

ESP_FORMER_SMOKER_BASELINE

Code List

Former smoking status at baseline [ 0=No, 1=Yes]

CL Item

No (0)

CL Item

Yes (1)

ESP_AGE_AT_MENARCHE

Item

Age at menarche

text

C1314691 (UMLS CUI [1,1])

ESP_AGE_AT_MENARCHE_CAT

Item

Age categories for menarche

text

C0001779 (UMLS CUI [1,1])
C0683312 (UMLS CUI [1,2])
C1314691 (UMLS CUI [1,3])

ESP_AGE_AT_MENARCHE_CAT

Code List

Age categories for menarche

CL Item

9 OR LESS (1)

CL Item

10 (2)

CL Item

11 (3)

CL Item

12 (4)

CL Item

13 (5)

CL Item

14 (6)

CL Item

15 (7)

CL Item

16 (8)

CL Item

17 OR OLDER (9)

ESP_AFIB_BASELINE

Item

Atrial fibrillation at baseline [ 0=No, 1=Yes]

text

C0004238 (UMLS CUI [1,1])
C1442488 (UMLS CUI [1,2])

ESP_AFIB_BASELINE

Code List

Atrial fibrillation at baseline [ 0=No, 1=Yes]

CL Item

No (0)

CL Item

Yes (1)

ESP_AFIB_DURING_FOLLOWUP

Item

0/1 - to indicate that an afib occurred during study follow up. 0 - if no afib during study follow up. 1 - if an adjudicated afib occurred during study follow up.

text

C1298908 (UMLS CUI [1,1])
C0004238 (UMLS CUI [1,2])
C0347984 (UMLS CUI [1,3])
C1522577 (UMLS CUI [1,4])
C0004238 (UMLS CUI [2,1])
C0347984 (UMLS CUI [2,2])
C1522577 (UMLS CUI [2,3])

ESP_AFIB_DURING_FOLLOWUP

Code List

0/1 - to indicate that an afib occurred during study follow up. 0 - if no afib during study follow up. 1 - if an adjudicated afib occurred during study follow up.

CL Item

No (0)

CL Item

Yes (1)

ESP_AFIB_TTE_OR_CENSOR

Item

Time to event variable for afib. Time (in days) from start of study to afib for event that occurred during study follow up; and follow up time for those that did not have an afib during study follow up.

text

C0040223 (UMLS CUI [1,1])
C1720302 (UMLS CUI [1,2])
C0004238 (UMLS CUI [1,3])
C0040223 (UMLS CUI [2,1])
C1522577 (UMLS CUI [2,2])

ESP_FASTINSULIN_BASELINE

Item

Blood fasting insulin at baseline in uU/mL. (Note that there are some extreme outliers)

text

C0015663 (UMLS CUI [1,1])
C0021641 (UMLS CUI [1,2])
C1442488 (UMLS CUI [1,3])

ESP_FASTGLUCOSE_BASELINE

Item

Blood fasting glucose at baseline in mg/dL

text

C0428568 (UMLS CUI [1,1])
C1442488 (UMLS CUI [1,2])

ESP_FIBRINOGEN

Item

Fibrinogen level in mg/dL at first designated visit (may not be baseline)

text

C0016006 (UMLS CUI [1,1])
C1524084 (UMLS CUI [1,2])
C0545082 (UMLS CUI [1,3])

ESP_AGE_AT_FIBRINOGEN

Item

Age in years at Fibrinogen measurement

text

C0001779 (UMLS CUI [1,1])
C0337428 (UMLS CUI [1,2])

ESP_FACTORVII

Item

Factor VII level in % at designated visit (may not be baseline)

text

C0427593 (UMLS CUI [1,1])
C1524084 (UMLS CUI [1,2])
C0545082 (UMLS CUI [1,3])

ESP_AGE_AT_FACTORVII

Item

Age in years at Factor VII measurement

text

C0001779 (UMLS CUI [1,1])
C0427593 (UMLS CUI [1,2])
C0242485 (UMLS CUI [1,3])

ESP_FACTORVIII

Item

Factor VIII level in % at designated visit (may not be baseline)

text

C2825857 (UMLS CUI [1,1])
C1524084 (UMLS CUI [1,2])
C0545082 (UMLS CUI [1,3])

ESP_AGE_AT_FACTORVIII

Item

Age in years at Factor VIII measurement

text

C0001779 (UMLS CUI [1,1])
C2825857 (UMLS CUI [1,2])

ESP_vWF

Item

VWF level in % at designated visit (may not be baseline)

text

C0427585 (UMLS CUI [1,1])
C1524084 (UMLS CUI [1,2])
C0545082 (UMLS CUI [1,3])

ESP_AGE_AT_vWF

Item

Age in years at visit of hemostatic factors measurement

text

C0001779 (UMLS CUI [1,1])
C0019116 (UMLS CUI [1,2])
C0242485 (UMLS CUI [1,3])

ESP_CRP

Item

C-reactive protein level in mg/L at designated visit (may not be baseline)

text

C0201657 (UMLS CUI [1,1])
C1524084 (UMLS CUI [1,2])
C0545082 (UMLS CUI [1,3])

ESP_AGE_AT_CRP

Item

Age in years at CRP measurement

text

C0001779 (UMLS CUI [1,1])
C0201657 (UMLS CUI [1,2])

ESP_IL6

Item

IL6 level in pg/mL at designated visit (may not be baseline)

text

C0919829 (UMLS CUI [1,1])
C1524084 (UMLS CUI [1,2])
C0545082 (UMLS CUI [1,3])

ESP_AGE_AT_IL6

Item

Age in years at IL6 measurement

text

C0001779 (UMLS CUI [1,1])
C0919829 (UMLS CUI [1,2])

ESP_ICAM1

Item

ICAM1 level in ng/mL at designated visit (may not be baseline)

text

C4084871 (UMLS CUI [1,1])
C1524084 (UMLS CUI [1,2])
C0545082 (UMLS CUI [1,3])

ESP_AGE_AT_ICAM1

Item

Age in years at ICAM1 measurement

text

C0001779 (UMLS CUI [1,1])
C4084871 (UMLS CUI [1,2])

ESP_PSELECTIN

Item

P-selectin level at designated visit (may not be baseline)

text

C3890352 (UMLS CUI [1,1])
C1524084 (UMLS CUI [1,2])
C0545082 (UMLS CUI [1,3])

ESP_AGE_AT_PSELECTIN

Item

Age in years at P-selectin measurement

text

C0001779 (UMLS CUI [1,1])
C3890352 (UMLS CUI [1,2])

ESP_WBC

Item

White blood count in x1,000/cubic mm at designated visit (may not be baseline)

text

C0023508 (UMLS CUI [1,1])
C1524084 (UMLS CUI [1,2])
C0545082 (UMLS CUI [1,3])

ESP_AGE_AT_WBC

Item

Age in years at WBC measurement

text

C0001779 (UMLS CUI [1,1])
C0023508 (UMLS CUI [1,2])

ESP_HEMOGLOBIN

Item

Hemoglobin at designated visit (may not be baseline) in g/dl

text

C0518015 (UMLS CUI [1,1])
C1524084 (UMLS CUI [1,2])
C0545082 (UMLS CUI [1,3])

ESP_AGE_AT_HEMOGLOBIN

Item

Age in years at hemoglobin measurement

text

C0001779 (UMLS CUI [1,1])
C0518015 (UMLS CUI [1,2])

ESP_HEMATOCRIT

Item

Hematocrit at designated visit (may not be baseline) in %

text

C0518014 (UMLS CUI [1,1])
C1524084 (UMLS CUI [1,2])
C0545082 (UMLS CUI [1,3])

ESP_AGE_AT_HEMATOCRIT

Item

Age in years at hematocrit measurement

text

C0001779 (UMLS CUI [1,1])
C0518014 (UMLS CUI [1,2])

ESP_PLATELET_COUNT

Item

Platelet count at designated visit (may not be baseline) in x 1000/cubic mm

text

C0032181 (UMLS CUI [1,1])
C1524084 (UMLS CUI [1,2])
C0545082 (UMLS CUI [1,3])

ESP_AGE_AT_PLATELET_COUNT

Item

Age in years at platelet count measurement

text

C0001779 (UMLS CUI [1,1])
C0032181 (UMLS CUI [1,2])

ESP_MEAN_CORPUSCULAR_VOLUME

Item

Mean corpuscular volume in femtoliters at designated visit (may not be baseline)

text

C1948043 (UMLS CUI [1,1])
C1524084 (UMLS CUI [1,2])
C0545082 (UMLS CUI [1,3])

ESP_AGE_AT_MCV

Item

Age in years at mean corpuscular volume measurement

text

C0001779 (UMLS CUI [1,1])
C1948043 (UMLS CUI [1,2])

ESP_RED_BLOOD_COUNT

Item

Red blood cell count in million cells per microliter at designated visit (may not be baseline)

text

C0014772 (UMLS CUI [1,1])
C1524084 (UMLS CUI [1,2])
C0545082 (UMLS CUI [1,3])

ESP_AGE_AT_RBC

Item

Age in years at red blood cell count measurement

text

C0001779 (UMLS CUI [1,1])
C0014772 (UMLS CUI [1,2])

ESP_NEUTROPHILS

Item

Neutrophils in absolute numbers at designated visit (may not be baseline).

text

C0200633 (UMLS CUI [1,1])
C1524084 (UMLS CUI [1,2])
C0545082 (UMLS CUI [1,3])

ESP_MONOCYTES

Item

Monocytes in absolute numbers at designated visit (may not be baseline).

text

C0200637 (UMLS CUI [1,1])
C1524084 (UMLS CUI [1,2])
C0545082 (UMLS CUI [1,3])

ESP_LYMPHOCYTES

Item

Lymphocytes in absolute numbers at designated visit (may not be baseline).

text

C0200635 (UMLS CUI [1,1])
C1524084 (UMLS CUI [1,2])
C0545082 (UMLS CUI [1,3])

ESP_EOSINOPHILS

Item

Eosinophils in absolute numbers at designated visit (may not be baseline).

text

C0200638 (UMLS CUI [1,1])
C1524084 (UMLS CUI [1,2])
C0545082 (UMLS CUI [1,3])

ESP_BASOPHILS

Item

Basophils in absolute numbers at designated visit (may not be baseline)

text

C0200641 (UMLS CUI [1,1])
C1524084 (UMLS CUI [1,2])
C0545082 (UMLS CUI [1,3])

ESP_AGE_AT_SECONDARY_BLOOD_COUNT

Item

Age in years at secondary blood count measurements (MCV, RBC, Neutrophils, Monocytes, Lymphocytes, Eosinophils, Basophils)

text

C0001779 (UMLS CUI [1,1])
C0009555 (UMLS CUI [1,2])

ESP_ANGIOPLASTY_BASELINE

Item

Baseline angioplasty status [ 0=No, 1=Yes]

text

C0162577 (UMLS CUI [1,1])
C0449438 (UMLS CUI [1,2])
C1442488 (UMLS CUI [1,3])

ESP_ANGIOPLASTY_BASELINE

Code List

Baseline angioplasty status [ 0=No, 1=Yes]

CL Item

No (0)

CL Item

Yes (1)

ESP_CABG_BASELINE

Item

Baseline CABG status [ 0=No, 1=Yes]

text

C0010055 (UMLS CUI [1,1])
C0449438 (UMLS CUI [1,2])
C1442488 (UMLS CUI [1,3])

ESP_CABG_BASELINE

Code List

Baseline CABG status [ 0=No, 1=Yes]

CL Item

No (0)

CL Item

Yes (1)

ESP_CAC_AGATSTON_SCORE

Item

Coronary artery calcium Agatston total score

text

C1956346 (UMLS CUI [1,1])
C1533591 (UMLS CUI [1,2])
C0449820 (UMLS CUI [1,3])

ESP_AGE_AT_CAC

Item

Age in years at CAC Agatston score measurement

text

C0001779 (UMLS CUI [1,1])
C1533591 (UMLS CUI [1,2])
C0449820 (UMLS CUI [1,3])
C0242485 (UMLS CUI [1,4])

ESP_IMT_MEANMEAN_FARWALL_CCA

Item

Average far wall thickness of the right and left common carotid mean IMT values, using as many views as are available for a given study

text

C1510992 (UMLS CUI [1,1])
C0226086 (UMLS CUI [1,2])
C0226087 (UMLS CUI [1,3])
C3517541 (UMLS CUI [1,4])

ESP_IMT_MEANMEAN_FARWALL_ICA

Item

Average far wall thickness of the right and left internal carotid maximum IMT values, using as many views as are available for a given study

text

C1510992 (UMLS CUI [1,1])
C0226086 (UMLS CUI [1,2])
C0226087 (UMLS CUI [1,3])
C3517541 (UMLS CUI [1,4])

ESP_IMT_ANYPLAQUE

Item

Presence of any plaque, as determined by IMT at designated visit (may not be baseline).

text

C0150312 (UMLS CUI [1,1])
C2936350 (UMLS CUI [1,2])
C3517541 (UMLS CUI [1,3])
C1524084 (UMLS CUI [1,4])
C0545082 (UMLS CUI [1,5])

ESP_IMT_ANYPLAQUE

Code List

Presence of any plaque, as determined by IMT at designated visit (may not be baseline).

CL Item

No (0)

CL Item

Yes (1)

ESP_AGE_AT_IMT

Item

Age in years at IMT measurement

text

C0001779 (UMLS CUI [1,1])
C3517541 (UMLS CUI [1,2])

ESP_EKG_QRS

Item

QRS interval from EKG at designated visit (may not be baseline)

text

C0429025 (UMLS CUI [1,1])
C1524084 (UMLS CUI [1,2])
C0545082 (UMLS CUI [1,3])

ESP_EKG_RR

Item

RR interval from EKG at designated visit (may not be baseline)

text

C0489636 (UMLS CUI [1,1])
C1524084 (UMLS CUI [1,2])
C0545082 (UMLS CUI [1,3])

ESP_EKG_QT

Item

QT interval from EKG at designated visit (may not be baseline)

text

C1287082 (UMLS CUI [1,1])
C1524084 (UMLS CUI [1,2])
C0545082 (UMLS CUI [1,3])

ESP_EKG_PR

Item

PR interval from EKG at designated visit (may not be baseline)

text

C0429087 (UMLS CUI [1,1])
C1524084 (UMLS CUI [1,2])
C0545082 (UMLS CUI [1,3])

ESP_EKG_HR

Item

HR interval from EKG at designated visit (may not be baseline)

text

C0522055 (UMLS CUI [1,1])
C1524084 (UMLS CUI [1,2])
C0545082 (UMLS CUI [1,3])

ESP_LVH_AT_EKG

Item

Left ventricular hypertrophy status at baseline [ 0=No, 1=Yes]

text

C0149721 (UMLS CUI [1,1])
C0449438 (UMLS CUI [1,2])
C1442488 (UMLS CUI [1,3])

ESP_AFLUT_AT_EKG

Item

Atrial flutter at EKG

text

C0004239 (UMLS CUI [1,1])
C0438154 (UMLS CUI [1,2])

ESP_WPW_AT_EKG

Item

Wolf-Parkinson-White pattern

text

C0043202 (UMLS CUI [1,1])

ESP_AVBLOCK2_AT_EKG

Item

Second degree AV block

text

C0264906 (UMLS CUI [1,1])

ESP_AVBLOCK3_AT_EKG

Item

Third degree AV block

text

C0151517 (UMLS CUI [1,1])

ESP_CORNELL_VOLTAGE_EKG

Item

Cornell voltage for EKG measurement, for EKG group.

text

C0438154 (UMLS CUI [1,1])
C0598352 (UMLS CUI [1,2])

ESP_CORNELL_VOLTAGE_EKG

Code List

Cornell voltage for EKG measurement, for EKG group.

CL Item

No (0)

CL Item

Yes (1)

ESP_PACER_EKG

Item

Pacer at EKG

text

C0030163 (UMLS CUI [1,1])
C0438154 (UMLS CUI [1,2])

ESP_PACER_EKG

Code List

Pacer at EKG

CL Item

No (0)

CL Item

Yes (1)

ESP_DIGOXIN_EKG

Item

Digoxin, for EKG group

text

C0012265 (UMLS CUI [1,1])

ESP_DIGOXIN_EKG

Code List

Digoxin, for EKG group

CL Item

No (0)

CL Item

Yes (1)

ESP_DIHYDRO_CALCIUM_CHANNEL_BLOC

Item

Dihydropyridine calcium channel blockers

text

C2945601 (UMLS CUI [1,1])

ESP_DIHYDRO_CALCIUM_CHANNEL_BLOC

Code List

Dihydropyridine calcium channel blockers

CL Item

No (0)

CL Item

Yes (1)

ESP_NONDIHYDRO_CALCIUM_CHANNEL_B

Item

Non-dihydropyridine calcium channel blockers, for EKG group.

text

C1298908 (UMLS CUI [1,1])
C2945601 (UMLS CUI [1,2])
C0006684 (UMLS CUI [1,3])

ESP_NONDIHYDRO_CALCIUM_CHANNEL_B

Code List

Non-dihydropyridine calcium channel blockers, for EKG group.

CL Item

No (0)

CL Item

Yes (1)

ESP_CALCIUM_CHANNEL_BLOCKERS_EKG

Item

Any Calc Channel blocker (only for ARIC - other HeartGO cohorts have this broken down by Dihydro versus Non-Dihydro)

text

C0006684 (UMLS CUI [1,1])

ESP_CALCIUM_CHANNEL_BLOCKERS_EKG

Code List

Any Calc Channel blocker (only for ARIC - other HeartGO cohorts have this broken down by Dihydro versus Non-Dihydro)

CL Item

No (0)

CL Item

Yes (1)

ESP_BETA_BLOCKERS_EKG

Item

Betablockers, for EKG group.

text

C0304516 (UMLS CUI [1,1])

ESP_BETA_BLOCKERS_EKG

Code List

Betablockers, for EKG group.

CL Item

No (0)

CL Item

Yes (1)

ESP_AGE_AT_EKG

Item

Age in years at EKG measurement

text

C0001779 (UMLS CUI [1,1])
C0430456 (UMLS CUI [1,2])

ESP_SERUM_CYSTATINC

Item

Raw cystatin C (mg/L)

text

C1619716 (UMLS CUI [1,1])

ESP_AGE_AT_SERUM_CYSTATINC

Item

Age in years at serum cystatin c measurement

text

C0001779 (UMLS CUI [1,1])
C1619716 (UMLS CUI [1,2])

ESP_URIC_ACID

Item

Uric acid in mg/dL

text

C0202239 (UMLS CUI [1,1])

ESP_AGE_AT_URIC_ACID

Item

Age in years at uric acid measurement

text

C0001779 (UMLS CUI [1,1])
C0202239 (UMLS CUI [1,2])

ESP_URINARY_ALBUMIN

Item

Raw urinary albumin. Note: Users need to confirm units are the same across cohorts

text

C1524119 (UMLS CUI [1,1])
C0201838 (UMLS CUI [1,2])

ESP_AGE_AT_URINARY_ALBUMIN

Item

Age in years at urinary albumin measurement

text

C0001779 (UMLS CUI [1,1])
C1524119 (UMLS CUI [1,2])
C0201838 (UMLS CUI [1,3])

ESP_URINARY_CREATININE

Item

Raw urinary creatinine in mg/dL

text

C1524119 (UMLS CUI [1,1])
C0201975 (UMLS CUI [1,2])

ESP_AGE_AT_URINARY_CREATININE

Item

Age in years at urinary creatinine measurement

text

C0001779 (UMLS CUI [1,1])
C1524119 (UMLS CUI [1,2])
C0201975 (UMLS CUI [1,3])

ESP_GOUT

Item

May be MD-reported, self-reported, or abstracted from patients taking allopurinol. Ever had gout through study.

text

C0031831 (UMLS CUI [1,1])
C0018099 (UMLS CUI [1,2])
C4319718 (UMLS CUI [1,3])
C2700446 (UMLS CUI [2,1])
C0018099 (UMLS CUI [2,2])
C1524063 (UMLS CUI [3,1])
C0002144 (UMLS CUI [3,2])
C0018099 (UMLS CUI [3,3])

ESP_GOUT

Code List

May be MD-reported, self-reported, or abstracted from patients taking allopurinol. Ever had gout through study.

CL Item

No (0)

CL Item

Yes (1)

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