Engels

This dataset provides refractive error values obtained from control subjects of the AREDS study (phs000001.v3.p1) and represents a substudy of AREDS ; data of n=7 new variables are provided in addition to basic sociodemographic data. Subject - consent and subject - sample mapping information is available through phs000001.v3.p1.

19 Formulieren  
  1. StudyEvent: NEI Age-Related Eye Disease Study (AREDS)
    1. Eligibility Criteria
    2. The data table (n=142 variables) contains AMD and cataract phenotype information, medical history and socio-demographic information drawn from several data sets (e.g. enrollment_randomization, amdlensphenotype, followup), plus a unique patient identifier (ID2) for participants with a genetic specimen (to be found only in GENSPECPHENOTYPE and GENSPECFUNDUSLENS [pht000376] tables). Nuclear, cortical and posterior subcapsular opacity information is included for both eyes at baseline and end of study. Other disease information (e.g. diabetes, cancer, angina), medical information (e.g. BMI, blood pressure) and smoking status are also included annually throughout follow-up.
    3. The data table (n=12 variables) contains information about the occurrence of adverse events during the AREDS clinical trial, e.g. type of adverse event, severity, primary ICD9 code, outcome, potential relationship to study drug, timing, and treatment. Data were collected through the clinical trial and for the first 6 months of the natural history follow-up immediately after the clinical trial concluded. Note: In version 3, the ID has been replaced by ID2 identifier for all subjects.
    4. The data table (n=25 variables) contains detailed information about cataract phenotypes (n=23 variables) as well as final AMD phenotype (n=1 variable), and patient ID. Nuclear, cortical and posterior subcapsular opacity information is included for both eyes at baseline and end of study. Note: In version 3, the ID has been replaced by ID2 identifier for all subjects.
    5. The data table (n=56 variables) contains information about AREDS participants' dietary intake of alcohol, amino acids, carbohydrates, fiber, poly- and monounsaturated fatty acids, proteins, vitamins and minerals. Participants' glycemic index and glycemic load are also included. Note: In version 3, the ID has been replaced by ID2 identifier for all subjects.
    6. The data table (n=102 variables) contains AREDS treatment assignment, basic socio-demographic characteristics and baseline medical history for AREDS participants. Medical history information includes eye disease information such as AMD Category, visual acuity, and past ophthalmic treatments (e.g. cataract surgery, laser treatment), as well as information about the presence/absence of other diseases (e.g. angina, arthritis, cancer, diabetes, high blood pressure), use of prescribed drugs for disease management (e.g. blood-thinning medications, digoxin, thyroid hormones, insulin), use of over-the-counter drugs (e.g. NSAIDs, antacids), intake of vitamins and minerals, and smoking history. Note: In version 3, the ID has been replaced by ID2 identifier for all subjects.
    7. The data table (n=83 variables) contains information obtained at follow-up visits during the AREDS clinical trial (every six months following randomization), annually in person during the natural history follow-up, and via phone between annual in-person visits. Variables include information about AREDS participants' ophthalmic medical history (e.g. cataract or other eye surgery, laser treatment for AMD, retinal repair, capsulotomy, presence/absence of lens, glaucoma, and visual acuity) and general medical information, including new diagnoses of cancer, heart disease, stroke, and peripheral vascular disease, disease history of angina and high blood pressure, current disease status of diabetes, arthritis, and gout, use of prescribed drugs for disease treatment or management (e.g. blood-thinning medications, digoxin, thyroid hormones, insulin), use of over-the-counter drugs (e.g. NSAIDs, antacids), and smoking behavior. For version 3 release of the study, visual acuity data of the right eye have been added for odd-numbered visits. Note: In version 3, the ID has been replaced by ID2 identifier for all subjects.
    8. The data table (n=49 variables) contains information from AREDS participants' fundus photographs, including presence, type, and extent of drusen, presence/extent of RPE depigmentation, SSR (serous sensory retinal) detachments, subretinal hemorrhages, subretinal fibrosis, and geographic atrophy. In addition, information on photocoagulation (PC) treatment for AMD SRNV is included, as well as AMD Severity Scale Scores and AMD Simple Scale Scores calculated from the fundus data. Note: In version 3, the ID has been replaced by ID2 identifier for all subjects.
    9. The data table (n=62) contains information only for AREDS participants who have a genetic specimen. A unique patient identifier (ID2 field) for these participants (to be found only in GENSPECPHENOTYPE [pht000001.v2.p1] and GENSPECFUNDUSLENS data tables) is included instead of the patient identifier used for data tables with all participants (ID field). Information about fundus and lens characteristics are included as follows - fundus: presence, type, and extent of drusen, presence/extent of RPE depigmentation, SSR (serous sensory retinal) detachments, subretinal hemorrhages, subretinal fibrosis, and geographic atrophy; lens: degree of nuclear sclerosis, cortical and posterior subcapsular opacities, and iris pigmentation. In addition, information on photocoagulation (PC) treatment for AMD is included as well as AMD Severity Scale Scores and AMD Simple Scale Scores calculated from the fundus data.
    10. The data table (n=6 variables) contains information about AREDS participant hospitalizations (e.g. reason, time from randomization, duration, primary ICD9 code) during the entire study. Note: In version 3, the ID has been replaced by ID2 identifier for all subjects.
    11. The data table (n=21 variables) contains information from AREDS participants' lens photographs, including degree of nuclear sclerosis, cortical and posterior subcapsular opacities, and iris pigmentation. Note: In version 3, the ID has been replaced by ID2 identifier for all subjects.
    12. The data table (n=7 variables) contains information about AREDS participant deaths (e.g. cause, time from randomization) during the entire study. A search using the National Death Index (NDI) yielded additional deaths not identified during the study. Note: In version 3, the ID has been replaced by ID2 identifier for all subjects.
    13. The data table (n=44 variables) contains information about AREDS participants' use (e.g. type, frequency, dose, duration) of non-steroidal anti-inflammatory drugs (e.g. aspirin, ibuprofen, acetaminophen, naproxen). Data were collected at in-clinic visits starting in October 2004. Note: In version 3, the ID has been replaced by ID2 identifier for all subjects.
    14. The data table (n=16 variables) contains information about AREDS participants' general vision status (e.g. general vision score, ocular pain score, VFQ overall score), and its effect on participants' behavior (e.g. near and distant activities, social activities, driving, mental health score) as obtained through the VFQ-25 questionnaire. Note: In version 3, the ID has been replaced by ID2 identifier for all subjects.
    15. Subject - Consent Information
    16. Subject - Sample Mapping (including mapping to Coriell IDs)
    17. The data table (n=2 variables) contains information on subjects' annual exposure to sunlight (hours; April through September).
    18. This dataset provides refractive error values obtained from control subjects of the AREDS study (phs000001.v3.p1) and represents a substudy of AREDS ; data of n=7 new variables are provided in addition to basic sociodemographic data. Subject - consent and subject - sample mapping information is available through phs000001.v3.p1.
    19. This dataset provides refractive error values obtained from control subjects of the AREDS study (phs000001.v3.p1) and represents a substudy of AREDS ; data of n=7 new variables are provided in addition to basic sociodemographic data. Subject - consent and subject - sample mapping information is available through phs000001.v3.p1.
pht002481
Beschrijving

pht002481

Subject deidentified AREDS study id
Beschrijving

SUBJID

Datatype

text

Alias
UMLS CUI [1,1]
C2348585
UMLS CUI [1,2]
C2346787
Case or control?
Beschrijving

case_control

Datatype

text

Alias
UMLS CUI [1,1]
C1706256
UMLS CUI [1,2]
C0009932
Sex of participant
Beschrijving

SEX

Datatype

text

Alias
UMLS CUI [1,1]
C0150831
Level of education
Beschrijving

SCHOOL

Datatype

text

Alias
UMLS CUI [1,1]
C0013658
Age of participant
Beschrijving

ENROLLAGE

Datatype

float

Alias
UMLS CUI [1,1]
C0001779
Race of participant
Beschrijving

WHITE

Datatype

text

Alias
UMLS CUI [1,1]
C0015031
Baseline right axis
Beschrijving

axisrr

Datatype

text

Maateenheden
  • Degrees
Alias
UMLS CUI [1,1]
C1442488
UMLS CUI [1,2]
C0429590
UMLS CUI [1,3]
C0229089
Degrees
Baseline left axis
Beschrijving

axisrl

Datatype

text

Maateenheden
  • Degrees
Alias
UMLS CUI [1,1]
C1442488
UMLS CUI [1,2]
C0429590
UMLS CUI [1,3]
C0229090
Degrees
Baseline right sphere number
Beschrijving

resphnum

Datatype

float

Maateenheden
  • Diopter
Alias
UMLS CUI [1,1]
C1442488
UMLS CUI [1,2]
C0946401
UMLS CUI [1,3]
C0229089
UMLS CUI [1,4]
C0237753
Diopter
Baseline left sphere number
Beschrijving

lesphnum

Datatype

float

Maateenheden
  • Diopter
Alias
UMLS CUI [1,1]
C1442488
UMLS CUI [1,2]
C0946401
UMLS CUI [1,3]
C0229090
UMLS CUI [1,4]
C0237753
Diopter
Baseline right cylinder number
Beschrijving

recylnum

Datatype

float

Maateenheden
  • Diopter
Alias
UMLS CUI [1,1]
C1442488
UMLS CUI [1,2]
C0429590
UMLS CUI [1,3]
C0229089
UMLS CUI [1,4]
C0237753
Diopter
Baseline left cylinder number
Beschrijving

lecylnum

Datatype

float

Maateenheden
  • Diopter
Alias
UMLS CUI [1,1]
C1442488
UMLS CUI [1,2]
C0429590
UMLS CUI [1,3]
C0229090
UMLS CUI [1,4]
C0237753
Diopter
Baseline right refractive error = resphnum + (0.5 * recylnum)
Beschrijving

RE_ERR_R

Datatype

float

Alias
UMLS CUI [1,1]
C1442488
UMLS CUI [1,2]
C3899481
UMLS CUI [1,3]
C0229089
Baseline left refractive error = lesphnum + (0.5 * lecylnum)
Beschrijving

LE_ERR_R

Datatype

float

Alias
UMLS CUI [1,1]
C1442488
UMLS CUI [1,2]
C3899481
UMLS CUI [1,3]
C0229090
Average of RE_ERR_R and LE_ERR_R
Beschrijving

AVG_ERR_R

Datatype

float

Alias
UMLS CUI [1,1]
C1510992
UMLS CUI [1,2]
C3899481
UMLS CUI [1,3]
C0229089
UMLS CUI [1,4]
C0229090
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Similar models

This dataset provides refractive error values obtained from control subjects of the AREDS study (phs000001.v3.p1) and represents a substudy of AREDS ; data of n=7 new variables are provided in addition to basic sociodemographic data. Subject - consent and subject - sample mapping information is available through phs000001.v3.p1.

19 Formulieren
  1. StudyEvent: NEI Age-Related Eye Disease Study (AREDS)
    1. Eligibility Criteria
    2. The data table (n=142 variables) contains AMD and cataract phenotype information, medical history and socio-demographic information drawn from several data sets (e.g. enrollment_randomization, amdlensphenotype, followup), plus a unique patient identifier (ID2) for participants with a genetic specimen (to be found only in GENSPECPHENOTYPE and GENSPECFUNDUSLENS [pht000376] tables). Nuclear, cortical and posterior subcapsular opacity information is included for both eyes at baseline and end of study. Other disease information (e.g. diabetes, cancer, angina), medical information (e.g. BMI, blood pressure) and smoking status are also included annually throughout follow-up.
    3. The data table (n=12 variables) contains information about the occurrence of adverse events during the AREDS clinical trial, e.g. type of adverse event, severity, primary ICD9 code, outcome, potential relationship to study drug, timing, and treatment. Data were collected through the clinical trial and for the first 6 months of the natural history follow-up immediately after the clinical trial concluded. Note: In version 3, the ID has been replaced by ID2 identifier for all subjects.
    4. The data table (n=25 variables) contains detailed information about cataract phenotypes (n=23 variables) as well as final AMD phenotype (n=1 variable), and patient ID. Nuclear, cortical and posterior subcapsular opacity information is included for both eyes at baseline and end of study. Note: In version 3, the ID has been replaced by ID2 identifier for all subjects.
    5. The data table (n=56 variables) contains information about AREDS participants' dietary intake of alcohol, amino acids, carbohydrates, fiber, poly- and monounsaturated fatty acids, proteins, vitamins and minerals. Participants' glycemic index and glycemic load are also included. Note: In version 3, the ID has been replaced by ID2 identifier for all subjects.
    6. The data table (n=102 variables) contains AREDS treatment assignment, basic socio-demographic characteristics and baseline medical history for AREDS participants. Medical history information includes eye disease information such as AMD Category, visual acuity, and past ophthalmic treatments (e.g. cataract surgery, laser treatment), as well as information about the presence/absence of other diseases (e.g. angina, arthritis, cancer, diabetes, high blood pressure), use of prescribed drugs for disease management (e.g. blood-thinning medications, digoxin, thyroid hormones, insulin), use of over-the-counter drugs (e.g. NSAIDs, antacids), intake of vitamins and minerals, and smoking history. Note: In version 3, the ID has been replaced by ID2 identifier for all subjects.
    7. The data table (n=83 variables) contains information obtained at follow-up visits during the AREDS clinical trial (every six months following randomization), annually in person during the natural history follow-up, and via phone between annual in-person visits. Variables include information about AREDS participants' ophthalmic medical history (e.g. cataract or other eye surgery, laser treatment for AMD, retinal repair, capsulotomy, presence/absence of lens, glaucoma, and visual acuity) and general medical information, including new diagnoses of cancer, heart disease, stroke, and peripheral vascular disease, disease history of angina and high blood pressure, current disease status of diabetes, arthritis, and gout, use of prescribed drugs for disease treatment or management (e.g. blood-thinning medications, digoxin, thyroid hormones, insulin), use of over-the-counter drugs (e.g. NSAIDs, antacids), and smoking behavior. For version 3 release of the study, visual acuity data of the right eye have been added for odd-numbered visits. Note: In version 3, the ID has been replaced by ID2 identifier for all subjects.
    8. The data table (n=49 variables) contains information from AREDS participants' fundus photographs, including presence, type, and extent of drusen, presence/extent of RPE depigmentation, SSR (serous sensory retinal) detachments, subretinal hemorrhages, subretinal fibrosis, and geographic atrophy. In addition, information on photocoagulation (PC) treatment for AMD SRNV is included, as well as AMD Severity Scale Scores and AMD Simple Scale Scores calculated from the fundus data. Note: In version 3, the ID has been replaced by ID2 identifier for all subjects.
    9. The data table (n=62) contains information only for AREDS participants who have a genetic specimen. A unique patient identifier (ID2 field) for these participants (to be found only in GENSPECPHENOTYPE [pht000001.v2.p1] and GENSPECFUNDUSLENS data tables) is included instead of the patient identifier used for data tables with all participants (ID field). Information about fundus and lens characteristics are included as follows - fundus: presence, type, and extent of drusen, presence/extent of RPE depigmentation, SSR (serous sensory retinal) detachments, subretinal hemorrhages, subretinal fibrosis, and geographic atrophy; lens: degree of nuclear sclerosis, cortical and posterior subcapsular opacities, and iris pigmentation. In addition, information on photocoagulation (PC) treatment for AMD is included as well as AMD Severity Scale Scores and AMD Simple Scale Scores calculated from the fundus data.
    10. The data table (n=6 variables) contains information about AREDS participant hospitalizations (e.g. reason, time from randomization, duration, primary ICD9 code) during the entire study. Note: In version 3, the ID has been replaced by ID2 identifier for all subjects.
    11. The data table (n=21 variables) contains information from AREDS participants' lens photographs, including degree of nuclear sclerosis, cortical and posterior subcapsular opacities, and iris pigmentation. Note: In version 3, the ID has been replaced by ID2 identifier for all subjects.
    12. The data table (n=7 variables) contains information about AREDS participant deaths (e.g. cause, time from randomization) during the entire study. A search using the National Death Index (NDI) yielded additional deaths not identified during the study. Note: In version 3, the ID has been replaced by ID2 identifier for all subjects.
    13. The data table (n=44 variables) contains information about AREDS participants' use (e.g. type, frequency, dose, duration) of non-steroidal anti-inflammatory drugs (e.g. aspirin, ibuprofen, acetaminophen, naproxen). Data were collected at in-clinic visits starting in October 2004. Note: In version 3, the ID has been replaced by ID2 identifier for all subjects.
    14. The data table (n=16 variables) contains information about AREDS participants' general vision status (e.g. general vision score, ocular pain score, VFQ overall score), and its effect on participants' behavior (e.g. near and distant activities, social activities, driving, mental health score) as obtained through the VFQ-25 questionnaire. Note: In version 3, the ID has been replaced by ID2 identifier for all subjects.
    15. Subject - Consent Information
    16. Subject - Sample Mapping (including mapping to Coriell IDs)
    17. The data table (n=2 variables) contains information on subjects' annual exposure to sunlight (hours; April through September).
    18. This dataset provides refractive error values obtained from control subjects of the AREDS study (phs000001.v3.p1) and represents a substudy of AREDS ; data of n=7 new variables are provided in addition to basic sociodemographic data. Subject - consent and subject - sample mapping information is available through phs000001.v3.p1.
    19. This dataset provides refractive error values obtained from control subjects of the AREDS study (phs000001.v3.p1) and represents a substudy of AREDS ; data of n=7 new variables are provided in addition to basic sociodemographic data. Subject - consent and subject - sample mapping information is available through phs000001.v3.p1.
Name
Type
Description | Question | Decode (Coded Value)
Datatype
Alias
Item Group
pht002481
SUBJID
Item
Subject deidentified AREDS study id
text
C2348585 (UMLS CUI [1,1])
C2346787 (UMLS CUI [1,2])
Item
Case or control?
text
C1706256 (UMLS CUI [1,1])
C0009932 (UMLS CUI [1,2])
case_control
Code List
Case or control?
CL Item
Control from original AREDS study (0)
C0009932 (UMLS CUI [1,1])
C0205313 (UMLS CUI [1,2])
Item
Sex of participant
text
C0150831 (UMLS CUI [1,1])
SEX
Code List
Sex of participant
CL Item
Male (1)
C0086582 (UMLS CUI [1,1])
CL Item
Female (2)
C0086287 (UMLS CUI [1,1])
Item
Level of education
text
C0013658 (UMLS CUI [1,1])
SCHOOL
Code List
Level of education
CL Item
Grade 11 or less (1)
C0013658 (UMLS CUI [1,1])
C1524031 (UMLS CUI [1,2])
CL Item
High school graduate (2)
C0870649 (UMLS CUI [1,1])
CL Item
Some college or associate degree (3)
C1883065 (UMLS CUI [1,1])
C1549943 (UMLS CUI [1,2])
CL Item
Bachelor's degree (4)
C1511035 (UMLS CUI [1,1])
CL Item
Postgraduate work (5)
C2983146 (UMLS CUI [1,1])
C0043227 (UMLS CUI [1,2])
CL Item
Refused to answer (6)
C1705116 (UMLS CUI [1,1])
C0508431 (UMLS CUI [1,2])
ENROLLAGE
Item
Age of participant
float
C0001779 (UMLS CUI [1,1])
Item
Race of participant
text
C0015031 (UMLS CUI [1,1])
WHITE
Code List
Race of participant
CL Item
White (1)
C0007457 (UMLS CUI [1,1])
CL Item
Other (non-white) (0)
C0205394 (UMLS CUI [1,1])
C1298908 (UMLS CUI [1,2])
C0007457 (UMLS CUI [1,3])
axisrr
Item
Baseline right axis
text
C1442488 (UMLS CUI [1,1])
C0429590 (UMLS CUI [1,2])
C0229089 (UMLS CUI [1,3])
axisrl
Item
Baseline left axis
text
C1442488 (UMLS CUI [1,1])
C0429590 (UMLS CUI [1,2])
C0229090 (UMLS CUI [1,3])
resphnum
Item
Baseline right sphere number
float
C1442488 (UMLS CUI [1,1])
C0946401 (UMLS CUI [1,2])
C0229089 (UMLS CUI [1,3])
C0237753 (UMLS CUI [1,4])
lesphnum
Item
Baseline left sphere number
float
C1442488 (UMLS CUI [1,1])
C0946401 (UMLS CUI [1,2])
C0229090 (UMLS CUI [1,3])
C0237753 (UMLS CUI [1,4])
recylnum
Item
Baseline right cylinder number
float
C1442488 (UMLS CUI [1,1])
C0429590 (UMLS CUI [1,2])
C0229089 (UMLS CUI [1,3])
C0237753 (UMLS CUI [1,4])
lecylnum
Item
Baseline left cylinder number
float
C1442488 (UMLS CUI [1,1])
C0429590 (UMLS CUI [1,2])
C0229090 (UMLS CUI [1,3])
C0237753 (UMLS CUI [1,4])
RE_ERR_R
Item
Baseline right refractive error = resphnum + (0.5 * recylnum)
float
C1442488 (UMLS CUI [1,1])
C3899481 (UMLS CUI [1,2])
C0229089 (UMLS CUI [1,3])
LE_ERR_R
Item
Baseline left refractive error = lesphnum + (0.5 * lecylnum)
float
C1442488 (UMLS CUI [1,1])
C3899481 (UMLS CUI [1,2])
C0229090 (UMLS CUI [1,3])
AVG_ERR_R
Item
Average of RE_ERR_R and LE_ERR_R
float
C1510992 (UMLS CUI [1,1])
C3899481 (UMLS CUI [1,2])
C0229089 (UMLS CUI [1,3])
C0229090 (UMLS CUI [1,4])
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