Inclusion Criteria
Item
*Inclusion Criteria:*
boolean
C1512693 (UMLS CUI [1,1])
Children aged 7-12 years of age who either have IBS or FAP or are healthy without complaints (Controls)
Item
Children aged 7-12 years of age who either have IBS or FAP or are healthy without complaints (Controls).
boolean
C1706256 (UMLS CUI [1,1])
C1512693 (UMLS CUI [1,2])
C0001779 (UMLS CUI [1,3])
C0022104 (UMLS CUI [1,4])
C0000737 (UMLS CUI [1,5])
C3898900 (UMLS CUI [1,6])
C1512693 (UMLS CUI [2,1])
C0009932 (UMLS CUI [2,2])
C0332288 (UMLS CUI [2,3])
C0871764 (UMLS CUI [2,4])
IBS
Item
IBS:
boolean
C1706256 (UMLS CUI [1,1])
C1512693 (UMLS CUI [1,2])
C0022104 (UMLS CUI [1,3])
Minimum of 1 healthcare visit for abdominal pain.
Item
Minimum of 1 healthcare visit for abdominal pain.
boolean
C1706256 (UMLS CUI [1,1])
C1512693 (UMLS CUI [1,2])
C1524031 (UMLS CUI [1,3])
C0205447 (UMLS CUI [1,4])
C0086388 (UMLS CUI [1,5])
C0545082 (UMLS CUI [1,6])
C0566251 (UMLS CUI [1,7])
C0000737 (UMLS CUI [1,8])
Minimum number of pain episodes of at least once per month, for three consecutive months within the year prior to enrolling in study.
Item
Minimum number of pain episodes of at least once per month, for three consecutive months within the year prior to enrolling in study.
boolean
C1706256 (UMLS CUI [1,1])
C1512693 (UMLS CUI [1,2])
C1524031 (UMLS CUI [1,3])
C4086638 (UMLS CUI [1,4])
C0030193 (UMLS CUI [1,5])
C3845349 (UMLS CUI [1,6])
C0347984 (UMLS CUI [1,7])
C1442461 (UMLS CUI [1,8])
C1707491 (UMLS CUI [1,9])
C0872291 (UMLS CUI [1,10])
C0205156 (UMLS CUI [1,11])
C4082117 (UMLS CUI [1,12])
Pain episodes have been severe enough to cause functional impairment; or have prompted medication use; or have been rated moderate to severe
Item
Pain episodes have been severe enough to cause functional impairment; or have prompted medication use; or have been rated moderate to severe (≥ 3/10).
boolean
C1706256 (UMLS CUI [1,1])
C1512693 (UMLS CUI [1,2])
C0030193 (UMLS CUI [1,3])
C0678227 (UMLS CUI [1,4])
C4062321 (UMLS CUI [1,5])
C1512693 (UMLS CUI [2,1])
C0030193 (UMLS CUI [2,2])
C0205263 (UMLS CUI [2,3])
C0240320 (UMLS CUI [2,4])
C1706256 (UMLS CUI [3,1])
C1512693 (UMLS CUI [3,2])
C0030193 (UMLS CUI [3,3])
C0871208 (UMLS CUI [3,4])
C1514721 (UMLS CUI [3,5])
C0205081 (UMLS CUI [3,6])
C0205082 (UMLS CUI [3,7])
Symptoms current.
Item
Symptoms current.
boolean
C1706256 (UMLS CUI [1,1])
C1512693 (UMLS CUI [1,2])
C1457887 (UMLS CUI [1,3])
C0521116 (UMLS CUI [1,4])
Less than 95th percentile blood pressure for age.
Item
Less than 95th percentile blood pressure for age.
boolean
C1706256 (UMLS CUI [1,1])
C1512693 (UMLS CUI [1,2])
C0005823 (UMLS CUI [1,3])
C0439092 (UMLS CUI [1,4])
C1264641 (UMLS CUI [1,5])
C0001779 (UMLS CUI [1,6])
Controls:
Item
Controls:
boolean
C0009932 (UMLS CUI [1,1])
Asymptomatic with regards to abdominal pain and without significant chronic health issues.
Item
Asymptomatic with regards to abdominal pain and without significant chronic health issues.
boolean
C1512693 (UMLS CUI [1,1])
C0009932 (UMLS CUI [1,2])
C1298908 (UMLS CUI [1,3])
C0000737 (UMLS CUI [1,4])
C1512693 (UMLS CUI [2,1])
C0009932 (UMLS CUI [2,2])
C1298908 (UMLS CUI [2,3])
C0008679 (UMLS CUI [2,4])
Less than 95% blood pressure for age
Item
Less than 95% blood pressure for age
boolean
C1512693 (UMLS CUI [1,1])
C0009932 (UMLS CUI [1,2])
C0439092 (UMLS CUI [1,3])
C1264641 (UMLS CUI [1,4])
C0005823 (UMLS CUI [1,5])
C0001779 (UMLS CUI [1,6])
Exclusion Criteria
Item
*Exclusion Criteria:*
boolean
C0680251 (UMLS CUI [1,1])
C1706256 (UMLS CUI [1,2])
IBS/FAP
Item
IBS/FAP:
boolean
C0680251 (UMLS CUI [1,1])
C1706256 (UMLS CUI [1,2])
C0022104 (UMLS CUI [1,3])
C0000737 (UMLS CUI [1,4])
Organic disease that accounts for abdominal pain
Item
Organic disease that accounts for abdominal pain.
boolean
C1706256 (UMLS CUI [1,1])
C0680251 (UMLS CUI [1,2])
C0683324 (UMLS CUI [1,3])
C0681841 (UMLS CUI [1,4])
C0000737 (UMLS CUI [1,5])
C0022104 (UMLS CUI [1,6])
Child currently taking an anti-inflammatory medication, or if their abdominal pain responded to an anti-inflammatory medication in the past.
Item
Child currently taking an anti-inflammatory medication, or if their abdominal pain responded to an anti-inflammatory medication in the past.
boolean
C1706256 (UMLS CUI [1,1])
C0022104 (UMLS CUI [1,2])
C0000737 (UMLS CUI [1,3])
C0680251 (UMLS CUI [1,4])
C3843777 (UMLS CUI [1,5])
C1706256 (UMLS CUI [2,1])
C0680251 (UMLS CUI [2,2])
C0000737 (UMLS CUI [2,3])
C0205342 (UMLS CUI [2,4])
C0003209 (UMLS CUI [2,5])
C1444637 (UMLS CUI [2,6])
Child currently taking medication for reflux to which abdominal pain symptoms are responding
Item
Child currently taking medication for reflux to which abdominal pain symptoms are responding.
boolean
C1706256 (UMLS CUI [1,1])
C0680251 (UMLS CUI [1,2])
C0521116 (UMLS CUI [1,3])
C0013227 (UMLS CUI [1,4])
C0017168 (UMLS CUI [1,5])
C0564405 (UMLS CUI [1,6])
C0000737 (UMLS CUI [1,7])
C0022104 (UMLS CUI [1,8])
Other chronic health condition or chronic illness (except mild intermittent or mild persistent asthma).
Item
Other chronic health condition or chronic illness (except mild intermittent or mild persistent asthma).
boolean
C1706256 (UMLS CUI [1,1])
C0680251 (UMLS CUI [1,2])
C0008679 (UMLS CUI [1,3])
C0205191 (UMLS CUI [1,4])
C0221423 (UMLS CUI [1,5])
C1705847 (UMLS CUI [1,6])
C1960046 (UMLS CUI [1,7])
C1960045 (UMLS CUI [1,8])
C0022104 (UMLS CUI [1,9])
C0000737 (UMLS CUI [1,10])
Cognitive impairment significantly below average age and/or grade level.
Item
Cognitive impairment significantly below average age and/or grade level.
boolean
C0680251 (UMLS CUI [1,1])
C0022104 (UMLS CUI [1,2])
C0000737 (UMLS CUI [1,3])
C1706256 (UMLS CUI [1,4])
C0338656 (UMLS CUI [1,5])
C0443151 (UMLS CUI [1,6])
C0001779 (UMLS CUI [1,7])
C0680251 (UMLS CUI [2,1])
C0022104 (UMLS CUI [2,2])
C0000737 (UMLS CUI [2,3])
C1706256 (UMLS CUI [2,4])
C0338656 (UMLS CUI [2,5])
C0443151 (UMLS CUI [2,6])
C0441800 (UMLS CUI [2,7])
Vomiting more than 2 times per month within 3 months prior to enrolling on study.
Item
Vomiting ≥ 2 times per month within 3 months prior to enrolling on study.
boolean
C1706256 (UMLS CUI [1,1])
C0680251 (UMLS CUI [1,2])
C0022104 (UMLS CUI [1,3])
C0000737 (UMLS CUI [1,4])
C0042963 (UMLS CUI [1,5])
C0439093 (UMLS CUI [1,6])
C0439603 (UMLS CUI [1,7])
C0205156 (UMLS CUI [1,8])
C1442461 (UMLS CUI [1,9])
Unintentional weight loss of more than 5% body weight within 3-month period
Item
Unintentional weight loss of ≥ 5% body weight within 3-month period.
boolean
C0680251 (UMLS CUI [1,1])
C1706256 (UMLS CUI [1,2])
C0000737 (UMLS CUI [1,3])
C0022104 (UMLS CUI [1,4])
C2363736 (UMLS CUI [1,5])
C0439093 (UMLS CUI [1,6])
C0439165 (UMLS CUI [1,7])
C0205451 (UMLS CUI [1,8])
C4086725 (UMLS CUI [1,9])
Females who have menses.
Item
Females who have menses.
boolean
C1706256 (UMLS CUI [1,1])
C0000737 (UMLS CUI [1,2])
C0680251 (UMLS CUI [1,3])
C0086287 (UMLS CUI [1,4])
C0025344 (UMLS CUI [1,5])
Use of the following drugs within the last 6 months
Item
Use of the following drugs within the last 6 months: systemic antibiotics, oral, intravenous, intramuscular, nasal or inhaled corticosteroids, cytokines, methotrexate or immunosuppressive cytotoxic agents, or large doses of commercial probiotics (10e8 cfu per day or higher).
boolean
C1706256 (UMLS CUI [1,1])
C0680251 (UMLS CUI [1,2])
C1524063 (UMLS CUI [1,3])
C0239126 (UMLS CUI [1,4])
C1527415 (UMLS CUI [1,5])
C1522726 (UMLS CUI [1,6])
C1556154 (UMLS CUI [1,7])
C0586793 (UMLS CUI [1,8])
C3539185 (UMLS CUI [1,9])
C1517741 (UMLS CUI [1,10])
C0205452 (UMLS CUI [1,11])
C0439231 (UMLS CUI [1,12])
C1706256 (UMLS CUI [2,1])
C0680251 (UMLS CUI [2,2])
C1524063 (UMLS CUI [2,3])
C0025677 (UMLS CUI [2,4])
C1517741 (UMLS CUI [2,5])
C0205452 (UMLS CUI [2,6])
C0439231 (UMLS CUI [2,7])
C1706256 (UMLS CUI [3,1])
C0680251 (UMLS CUI [3,2])
C1524063 (UMLS CUI [3,3])
C0079189 (UMLS CUI [3,4])
C1517741 (UMLS CUI [3,5])
C0205452 (UMLS CUI [3,6])
C0439231 (UMLS CUI [3,7])
C1706256 (UMLS CUI [4,1])
C0680251 (UMLS CUI [4,2])
C1524063 (UMLS CUI [4,3])
C3540704 (UMLS CUI [4,4])
C1517741 (UMLS CUI [4,5])
C0205452 (UMLS CUI [4,6])
C0439231 (UMLS CUI [4,7])
C1706256 (UMLS CUI [5,1])
C0680251 (UMLS CUI [5,2])
C1524063 (UMLS CUI [5,3])
C0021081 (UMLS CUI [5,4])
C0677881 (UMLS CUI [5,5])
C1517741 (UMLS CUI [5,6])
C0205452 (UMLS CUI [5,7])
C0439231 (UMLS CUI [5,8])
C1706256 (UMLS CUI [6,1])
C0680251 (UMLS CUI [6,2])
C1524063 (UMLS CUI [6,3])
C0549177 (UMLS CUI [6,4])
C0178602 (UMLS CUI [6,5])
C0680536 (UMLS CUI [6,6])
C1517741 (UMLS CUI [6,7])
C0525033 (UMLS CUI [6,8])
C0205452 (UMLS CUI [6,9])
C0439231 (UMLS CUI [6,10])
Major diet change in the past month prior to enrollmen
Item
Major diet change in the past month prior to enrollment (e.g., change to vegetarianism or vice versa; avoidance or inclusion of major food group [fruit, vegetables]). This does not include diet changes related to lactose intolerance.
boolean
C1706256 (UMLS CUI [1,1])
C0680251 (UMLS CUI [1,2])
C0205164 (UMLS CUI [1,3])
C3671772 (UMLS CUI [1,4])
C1444637 (UMLS CUI [1,5])
C0439231 (UMLS CUI [1,6])
Major surgery including surgery involving the gastrointestinal tract.
Item
Major surgery including surgery involving the gastrointestinal tract.
boolean
C0680251 (UMLS CUI [1,1])
C1706256 (UMLS CUI [1,2])
C0022104 (UMLS CUI [1,3])
C0000737 (UMLS CUI [1,4])
C0679637 (UMLS CUI [1,5])
C0524722 (UMLS CUI [1,6])
Controls
Item
Controls:
boolean
C0009932 (UMLS CUI [1,1])
C0680251 (UMLS CUI [1,2])
Other chronic illness or health condition or chronic illness (except mild intermittent or mild persistent asthma)
Item
Other chronic illness or health condition or chronic illness (except mild intermittent or mild persistent asthma)
boolean
C0009932 (UMLS CUI [1,1])
C0680251 (UMLS CUI [1,2])
C0008679 (UMLS CUI [1,3])
C1705847 (UMLS CUI [1,4])
C1960046 (UMLS CUI [1,5])
C1960045 (UMLS CUI [1,6])
Cognitive impairment significantly below average age and/or grade level
Item
Cognitive impairment significantly below average age and/or grade level
boolean
C0680251 (UMLS CUI [1,1])
C0009932 (UMLS CUI [1,2])
C0338656 (UMLS CUI [1,3])
C0443151 (UMLS CUI [1,4])
C0001779 (UMLS CUI [1,5])
C0680251 (UMLS CUI [2,1])
C0009932 (UMLS CUI [2,2])
C0338656 (UMLS CUI [2,3])
C0443151 (UMLS CUI [2,4])
C0441800 (UMLS CUI [2,5])
Child seen a physician more than once in past year for abdominal pain unexplained by common illness (e.g., gastroenteritis)
Item
Child seen a physician more than once in past year for abdominal pain unexplained by common illness (e.g., gastroenteritis)
boolean
C0680251 (UMLS CUI [1,1])
C0009932 (UMLS CUI [1,2])
C0583527 (UMLS CUI [1,3])
C0566251 (UMLS CUI [1,4])
C0000737 (UMLS CUI [1,5])
C0439093 (UMLS CUI [1,6])
C1948045 (UMLS CUI [1,7])
C3887293 (UMLS CUI [1,8])
C4288071 (UMLS CUI [1,9])
C0205214 (UMLS CUI [1,10])
C0221423 (UMLS CUI [1,11])
Females who have menses
Item
Females who have menses
boolean
C0009932 (UMLS CUI [1,1])
C0680251 (UMLS CUI [1,2])
C0086287 (UMLS CUI [1,3])
C0025344 (UMLS CUI [1,4])
Use of the following drugs within the last 6 months
Item
Use of the following drugs within the last 6 months: systemic antibiotics, oral, intravenous, intramuscular, nasal or inhaled corticosteroids, cytokines, methotrexate or immunosuppressive cytotoxic agents, or large doses of commercial probiotics (10e8 cfu per day or higher).
boolean
C0680251 (UMLS CUI [1,1])
C0009932 (UMLS CUI [1,2])
C1524063 (UMLS CUI [1,3])
C0239126 (UMLS CUI [1,4])
C1527415 (UMLS CUI [1,5])
C1522726 (UMLS CUI [1,6])
C1556154 (UMLS CUI [1,7])
C0586793 (UMLS CUI [1,8])
C3539185 (UMLS CUI [1,9])
C1517741 (UMLS CUI [1,10])
C0205452 (UMLS CUI [1,11])
C0439231 (UMLS CUI [1,12])
C0009932 (UMLS CUI [2,1])
C0680251 (UMLS CUI [2,2])
C1524063 (UMLS CUI [2,3])
C0549177 (UMLS CUI [2,4])
C0178602 (UMLS CUI [2,5])
C0680536 (UMLS CUI [2,6])
C0525033 (UMLS CUI [2,7])
C1517741 (UMLS CUI [2,8])
C0205452 (UMLS CUI [2,9])
C0439231 (UMLS CUI [2,10])
C0009932 (UMLS CUI [3,1])
C0680251 (UMLS CUI [3,2])
C1524063 (UMLS CUI [3,3])
C0021081 (UMLS CUI [3,4])
C0677881 (UMLS CUI [3,5])
C1517741 (UMLS CUI [3,6])
C0205452 (UMLS CUI [3,7])
C0439231 (UMLS CUI [3,8])
C0009932 (UMLS CUI [4,1])
C0680251 (UMLS CUI [4,2])
C1524063 (UMLS CUI [4,3])
C0025677 (UMLS CUI [4,4])
C1517741 (UMLS CUI [4,5])
C0205452 (UMLS CUI [4,6])
C0439231 (UMLS CUI [4,7])
C0009932 (UMLS CUI [5,1])
C0079189 (UMLS CUI [5,2])
C0680251 (UMLS CUI [5,3])
C1524063 (UMLS CUI [5,4])
C1517741 (UMLS CUI [5,5])
C0205452 (UMLS CUI [5,6])
C0439231 (UMLS CUI [5,7])
C0009932 (UMLS CUI [6,1])
C0680251 (UMLS CUI [6,2])
C1524063 (UMLS CUI [6,3])
C3540704 (UMLS CUI [6,4])
C1517741 (UMLS CUI [6,5])
C0205452 (UMLS CUI [6,6])
C0439231 (UMLS CUI [6,7])
Major diet change in the past month prior to enrollment
Item
Major diet change in the past month prior to enrollment (e.g., change to vegetarianism or vice versa; avoidance or inclusion of major food group [fruit, vegetables]). This does not include diet changes related to lactose intolerance.
boolean
C0009932 (UMLS CUI [1,1])
C0680251 (UMLS CUI [1,2])
C0205164 (UMLS CUI [1,3])
C1444637 (UMLS CUI [1,4])
C0439231 (UMLS CUI [1,5])
Major surgery including surgery involving the gastrointestinal tract.
Item
Major surgery including surgery involving the gastrointestinal tract.
boolean
C0009932 (UMLS CUI [1,1])
C0680251 (UMLS CUI [1,2])
C0679637 (UMLS CUI [1,3])
C0524722 (UMLS CUI [1,4])
Non-English speaking parent or child.
Item
Non-English speaking parent or child.
boolean
C0332268 (UMLS CUI [1,1])
C0564215 (UMLS CUI [1,2])
C0376245 (UMLS CUI [1,3])