Cases of medulloblastoma treated at St. Jude Children's Hospital - St. Jude Medulloblastoma 2003 trial (SJMB03) with central pathology review confirming the diagnosis of medulloblastoma. The cases in this cohort have had whole genome sequencing of tumor and normal DNA performed. Cases were selected that had appropriate consent for genetic studies, and suitable material for sequencing (high purity tumor populations and available normal DNA).