There were 2,967 cases and 3,075 controls run on Genome-Wide Human SNP Array 6.0 and analyzed for association testing. The age criteria for the cases was men ≤50 y old or women ≤60 y old. The samples were drawn from 6 collection sites: Boston, MA (Masschusetts General Hospital Premature Coronary Artery Disease Study), Seattle, WA (Heart Attack Risk in Puget Sound), Helsinki, Finland (FINRISK), Malmö, Sweden (Malmö Diet and Cancer Study), Barcelona, Spain (REGICOR), and Milan, Italy (Italian Atherosclerosis Thrombosis and Vascular Biology Working Group).