ID

44975

Description

Principal Investigator: J.H. Warram, Joslin Diabetes Center, Boston, MA, USA MeSH: https://www.ncbi.nlm.nih.gov/projects/gap/cgi-bin/study.cgi?study_id=phs000018 Genetics of Kidneys in Diabetes (GoKinD) study is an initiative aimed at identifying susceptibility genes for diabetic nephropathy in type 1 diabetes. A large number of individuals with type 1 diabetes were screened to identify two subsets, one with clear-cut kidney disease and another with normal renal status despite long-term diabetes. Those who met additional entry criteria and consented to participate were enrolled. When possible, both parents were also enrolled to form family trios. Altogether, GoKinD includes 3043 participants comprising 931 cases, 944 singletons, 268 pairs of parents of cases, and 316 pairs of parents of control. Accessible as a GAIN database are 905 of the cases, 890 of the controls, 10 pairs of parents of cases and 10 pairs of parents of controls. The other parents and the remaining cases and controls are available by a separate application process through NIDDK (dbGaP phs000088 *Search for Susceptibility Genes for Diabetic Nephropathy in Type 1 Diabetes (GoKinD study participants and parents), NIDDK*). Interested investigators may request the DNA collection and corresponding clinical data for GoKinD participants using the instructions and application form available at Juvenile Diabetes Research Foundation. *Consent groups and participant set* - Diabetic complications only (DCO): 1825 (904 cases, 881 controls, 40 others)

Link

https://www.ncbi.nlm.nih.gov/projects/gap/cgi-bin/study.cgi?study_id=phs000018

Keywords

  1. 5/12/22 5/12/22 - Martin Dugas
  2. 5/12/22 5/12/22 - Martin Dugas
  3. 5/20/22 5/20/22 - Dr. Christian Niklas
  4. 6/3/22 6/3/22 - Dr. Christian Niklas
  5. 10/12/22 10/12/22 - Adrian Schulz
Copyright Holder

J.H. Warram, Joslin Diabetes Center, Boston, MA, USA

Uploaded on

June 3, 2022

DOI

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License

Creative Commons BY-NC 4.0

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dbGaP phs000018 Search for Susceptibility Genes for Diabetic Nephropathy in Type 1 Diabetes (GoKinD study participants), GAIN

GoKinD - GAIN Pedigree Information

pht004355
Description

pht004355

Family ID
Description

family

Data type

text

Alias
UMLS CUI [1,1]
C3669174
Subject ID
Description

individual

Data type

text

Alias
UMLS CUI [1,1]
C2348585
Father's ID
Description

father

Data type

text

Alias
UMLS CUI [1,1]
C3669177
Mother's ID
Description

mother

Data type

text

Alias
UMLS CUI [1,1]
C3669352
Subject's sex
Description

sex

Data type

text

Alias
UMLS CUI [1,1]
C0079399
Case-Control
Description

class

Data type

text

Alias
UMLS CUI [1,1]
C3274646

Similar models

GoKinD - GAIN Pedigree Information

Name
Type
Description | Question | Decode (Coded Value)
Data type
Alias
Item Group
pht004355
family
Item
Family ID
text
C3669174 (UMLS CUI [1,1])
individual
Item
Subject ID
text
C2348585 (UMLS CUI [1,1])
father
Item
Father's ID
text
C3669177 (UMLS CUI [1,1])
mother
Item
Mother's ID
text
C3669352 (UMLS CUI [1,1])
Item
Subject's sex
text
C0079399 (UMLS CUI [1,1])
Code List
Subject's sex
CL Item
Male (1)
C0086582 (UMLS CUI [1,1])
CL Item
Female (2)
C0086287 (UMLS CUI [1,1])
Item
Case-Control
text
C3274646 (UMLS CUI [1,1])
Code List
Case-Control
CL Item
Control (CTRL)
C0009932 (UMLS CUI [1,1])

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