English

The data table (n=62) contains information only for AREDS participants who have a genetic specimen. A unique patient identifier (ID2 field) for these participants (to be found only in GENSPECPHENOTYPE [pht000001.v2.p1] and GENSPECFUNDUSLENS data tables) is included instead of the patient identifier used for data tables with all participants (ID field). Information about fundus and lens characteristics are included as follows - fundus: presence, type, and extent of drusen, presence/extent of RPE depigmentation, SSR (serous sensory retinal) detachments, subretinal hemorrhages, subretinal fibrosis, and geographic atrophy; lens: degree of nuclear sclerosis, cortical and posterior subcapsular opacities, and iris pigmentation. In addition, information on photocoagulation (PC) treatment for AMD is included as well as AMD Severity Scale Scores and AMD Simple Scale Scores calculated from the fundus data.

19 forms  
  1. StudyEvent: SEV1
    1. The data table (n=142 variables) contains AMD and cataract phenotype information, medical history and socio-demographic information drawn from several data sets (e.g. enrollment_randomization, amdlensphenotype, followup), plus a unique patient identifier (ID2) for participants with a genetic specimen (to be found only in GENSPECPHENOTYPE and GENSPECFUNDUSLENS [pht000376] tables). Nuclear, cortical and posterior subcapsular opacity information is included for both eyes at baseline and end of study. Other disease information (e.g. diabetes, cancer, angina), medical information (e.g. BMI, blood pressure) and smoking status are also included annually throughout follow-up.
    2. The data table (n=12 variables) contains information about the occurrence of adverse events during the AREDS clinical trial, e.g. type of adverse event, severity, primary ICD9 code, outcome, potential relationship to study drug, timing, and treatment. Data were collected through the clinical trial and for the first 6 months of the natural history follow-up immediately after the clinical trial concluded. Note: In version 3, the ID has been replaced by ID2 identifier for all subjects.
    3. The data table (n=25 variables) contains detailed information about cataract phenotypes (n=23 variables) as well as final AMD phenotype (n=1 variable), and patient ID. Nuclear, cortical and posterior subcapsular opacity information is included for both eyes at baseline and end of study. Note: In version 3, the ID has been replaced by ID2 identifier for all subjects.
    4. The data table (n=56 variables) contains information about AREDS participants' dietary intake of alcohol, amino acids, carbohydrates, fiber, poly- and monounsaturated fatty acids, proteins, vitamins and minerals. Participants' glycemic index and glycemic load are also included. Note: In version 3, the ID has been replaced by ID2 identifier for all subjects.
    5. The data table (n=102 variables) contains AREDS treatment assignment, basic socio-demographic characteristics and baseline medical history for AREDS participants. Medical history information includes eye disease information such as AMD Category, visual acuity, and past ophthalmic treatments (e.g. cataract surgery, laser treatment), as well as information about the presence/absence of other diseases (e.g. angina, arthritis, cancer, diabetes, high blood pressure), use of prescribed drugs for disease management (e.g. blood-thinning medications, digoxin, thyroid hormones, insulin), use of over-the-counter drugs (e.g. NSAIDs, antacids), intake of vitamins and minerals, and smoking history. Note: In version 3, the ID has been replaced by ID2 identifier for all subjects.
    6. The data table (n=83 variables) contains information obtained at follow-up visits during the AREDS clinical trial (every six months following randomization), annually in person during the natural history follow-up, and via phone between annual in-person visits. Variables include information about AREDS participants' ophthalmic medical history (e.g. cataract or other eye surgery, laser treatment for AMD, retinal repair, capsulotomy, presence/absence of lens, glaucoma, and visual acuity) and general medical information, including new diagnoses of cancer, heart disease, stroke, and peripheral vascular disease, disease history of angina and high blood pressure, current disease status of diabetes, arthritis, and gout, use of prescribed drugs for disease treatment or management (e.g. blood-thinning medications, digoxin, thyroid hormones, insulin), use of over-the-counter drugs (e.g. NSAIDs, antacids), and smoking behavior. For version 3 release of the study, visual acuity data of the right eye have been added for odd-numbered visits. Note: In version 3, the ID has been replaced by ID2 identifier for all subjects.
    7. The data table (n=49 variables) contains information from AREDS participants' fundus photographs, including presence, type, and extent of drusen, presence/extent of RPE depigmentation, SSR (serous sensory retinal) detachments, subretinal hemorrhages, subretinal fibrosis, and geographic atrophy. In addition, information on photocoagulation (PC) treatment for AMD SRNV is included, as well as AMD Severity Scale Scores and AMD Simple Scale Scores calculated from the fundus data. Note: In version 3, the ID has been replaced by ID2 identifier for all subjects.
    8. The data table (n=62) contains information only for AREDS participants who have a genetic specimen. A unique patient identifier (ID2 field) for these participants (to be found only in GENSPECPHENOTYPE [pht000001.v2.p1] and GENSPECFUNDUSLENS data tables) is included instead of the patient identifier used for data tables with all participants (ID field). Information about fundus and lens characteristics are included as follows - fundus: presence, type, and extent of drusen, presence/extent of RPE depigmentation, SSR (serous sensory retinal) detachments, subretinal hemorrhages, subretinal fibrosis, and geographic atrophy; lens: degree of nuclear sclerosis, cortical and posterior subcapsular opacities, and iris pigmentation. In addition, information on photocoagulation (PC) treatment for AMD is included as well as AMD Severity Scale Scores and AMD Simple Scale Scores calculated from the fundus data.
    9. The data table (n=6 variables) contains information about AREDS participant hospitalizations (e.g. reason, time from randomization, duration, primary ICD9 code) during the entire study. Note: In version 3, the ID has been replaced by ID2 identifier for all subjects.
    10. The data table (n=21 variables) contains information from AREDS participants' lens photographs, including degree of nuclear sclerosis, cortical and posterior subcapsular opacities, and iris pigmentation. Note: In version 3, the ID has been replaced by ID2 identifier for all subjects.
    11. The data table (n=7 variables) contains information about AREDS participant deaths (e.g. cause, time from randomization) during the entire study. A search using the National Death Index (NDI) yielded additional deaths not identified during the study. Note: In version 3, the ID has been replaced by ID2 identifier for all subjects.
    12. The data table (n=44 variables) contains information about AREDS participants' use (e.g. type, frequency, dose, duration) of non-steroidal anti-inflammatory drugs (e.g. aspirin, ibuprofen, acetaminophen, naproxen). Data were collected at in-clinic visits starting in October 2004. Note: In version 3, the ID has been replaced by ID2 identifier for all subjects.
    13. The data table (n=16 variables) contains information about AREDS participants' general vision status (e.g. general vision score, ocular pain score, VFQ overall score), and its effect on participants' behavior (e.g. near and distant activities, social activities, driving, mental health score) as obtained through the VFQ-25 questionnaire. Note: In version 3, the ID has been replaced by ID2 identifier for all subjects.
    14. Subject - Consent Information
    15. Subject - Sample Mapping (including mapping to Coriell IDs)
    16. The data table (n=2 variables) contains information on subjects' annual exposure to sunlight (hours; April through September).
    17. This dataset provides refractive error values obtained from control subjects of the AREDS study (phs000001.v3.p1) and represents a substudy of AREDS ; data of n=7 new variables are provided in addition to basic sociodemographic data. Subject - consent and subject - sample mapping information is available through phs000001.v3.p1.
    18. This dataset provides refractive error values obtained from control subjects of the AREDS study (phs000001.v3.p1) and represents a substudy of AREDS ; data of n=7 new variables are provided in addition to basic sociodemographic data. Subject - consent and subject - sample mapping information is available through phs000001.v3.p1.
    19. This dataset provides refractive error values obtained from control subjects of the AREDS study (phs000001.v3.p1) and represents a substudy of AREDS ; data of n=7 new variables are provided in addition to basic sociodemographic data. Subject - consent and subject - sample mapping information is available through phs000001.v3.p1.
pht000376.v1.p1
Description

pht000376.v1.p1

DUMMY ID NUMBER (EYE DISEASE RESEARCH ONLY PARTICIPANTS HAVE A DIFFERENT DUMMY ID NUMBER)
Description

ID2

Data type

string

STUDY VISIT NUMBER (PARTICIPANTS WITH A GENETIC SPECIMEN)
Description

VISNO

Data type

text

DRUSENOID PED FIELD 2 RT EYE (PARTICIPANTS WITH A GENETIC SPECIMEN)
Description

REDRUSF2

Data type

text

NON-DRUSENOID PED FIELD 2 RT EYE (PARTICIPANTS WITH A GENETIC SPECIMEN)
Description

RENDRUF2

Data type

text

SSR/HEMORRHAGIC RD FIELD 2 RT EYE (PARTICIPANTS WITH A GENETIC SPECIMEN)
Description

RESSRF2

Data type

text

HARD EXUDATE FIELD 2 RT EYE (PARTICIPANTS WITH A GENETIC SPECIMEN)
Description

REHDEXF2

Data type

text

SUBRETINAL/SUBRPE HEMORRHAGE FIELD 2 RT EYE (PARTICIPANTS WITH A GENETIC SPECIMEN)
Description

RESUBHF2

Data type

text

SUBRETINAL FIBROSIS FIELD 2 RT EYE (PARTICIPANTS WITH A GENETIC SPECIMEN)
Description

RESUBFF2

Data type

text

PC/AMD FIELD 2 RT EYE (PARTICIPANTS WITH A GENETIC SPECIMEN)
Description

REPHCOF2

Data type

text

GEOGRAPHIC ATROPHY CENTER POINT RT EYE (PARTICIPANTS WITH A GENETIC SPECIMEN)
Description

REGEOACT

Data type

text

GEOGRAPHIC ATROPHY AREA C/SUB RT EYE (PARTICIPANTS WITH A GENETIC SPECIMEN)
Description

REGEOACS

Data type

text

GEOGRAPHIC ATROPHY W/I GRID RT EYE (PARTICIPANTS WITH A GENETIC SPECIMEN)
Description

REGEOAWI

Data type

text

RPE DEPIGMENTATION AREA C/SUB+INNERS RT EYE (PARTICIPANTS WITH A GENETIC SPECIMEN)
Description

RERPEDCI

Data type

text

RPE DEPIGMENTATION AREA W/I GRID RT EYE (PARTICIPANTS WITH A GENETIC SPECIMEN)
Description

RERPEDWI

Data type

text

INCREASED PIGMENT AREA C/SUB+INNERS RT EYE (PARTICIPANTS WITH A GENETIC SPECIMEN)
Description

REINCPCI

Data type

text

INCREASED PIGMENT AREA W/I GRID RT EYE (PARTICIPANTS WITH A GENETIC SPECIMEN)
Description

REINCPWI

Data type

text

MAXIMUM DRUSEN SIZE W/I GRID RT EYE (PARTICIPANTS WITH A GENETIC SPECIMEN)
Description

REDRSZWI

Data type

text

DRUSEN AREA W/I GRID (PARTICIPANTS WITH A GENETIC SPECIMEN)
Description

REDRARWI

Data type

text

DRUSEN CATEGORY RT EYE (PARTICIPANTS WITH A GENETIC SPECIMEN)
Description

REELICAT

Data type

text

DRUSENOID PED FIELD 2 LT EYE (PARTICIPANTS WITH A GENETIC SPECIMEN)
Description

LEDRUSF2

Data type

text

NON-DRUSENOID PED FIELD 2 LT EYE (PARTICIPANTS WITH A GENETIC SPECIMEN)
Description

LENDRUF2

Data type

text

SSR/HEMORRHAGIC RD FIELD 2 RT EYE (PARTICIPANTS WITH A GENETIC SPECIMEN)
Description

LESSRF2

Data type

text

HARD EXUDATE FIELD 2 LT EYE (PARTICIPANTS WITH A GENETIC SPECIMEN)
Description

LEHDEXF2

Data type

text

SUBRETINAL/SUBRPE HEMORRHAGE FIELD 2 LT EYE (PARTICIPANTS WITH A GENETIC SPECIMEN)
Description

LESUBHF2

Data type

text

SUBRETINAL FIBROSIS FIELD 2 LT EYE (PARTICIPANTS WITH A GENETIC SPECIMEN)
Description

LESUBFF2

Data type

text

PC/AMD FIELD 2 LT EYE (PARTICIPANTS WITH A GENETIC SPECIMEN)
Description

LEPHCOF2

Data type

text

GEOGRAPHIC ATROPHY CENTER POINT LT EYE (PARTICIPANTS WITH A GENETIC SPECIMEN)
Description

LEGEOACT

Data type

text

GEOGRAPHIC ATROPHY AREA C/SUB LT EYE (PARTICIPANTS WITH A GENETIC SPECIMEN)
Description

LEGEOACS

Data type

text

GEOGRAPHIC ATROPHY W/I GRID LT EYE (PARTICIPANTS WITH A GENETIC SPECIMEN)
Description

LEGEOAWI

Data type

text

RPE DEPIGMENTATION AREA C/SUB+INNERS LT EYE (PARTICIPANTS WITH A GENETIC SPECIMEN)
Description

LERPEDCI

Data type

text

RPE DEPIGMENTATION AREA W/I GRID LT EYE (PARTICIPANTS WITH A GENETIC SPECIMEN)
Description

LERPEDWI

Data type

text

INCREASED PIGMENT AREA C/SUB+INNERS LT EYE (PARTICIPANTS WITH A GENETIC SPECIMEN)
Description

LEINCPCI

Data type

text

INCREASED PIGMENT AREA W/I GRID LT EYE (PARTICIPANTS WITH A GENETIC SPECIMEN)
Description

LEINCPWI

Data type

text

MAXIMUM DRUSEN SIZE W/I GRID LT EYE (PARTICIPANTS WITH A GENETIC SPECIMEN)
Description

LEDRSZWI

Data type

text

DRUSEN AREA W/I GRID LT EYE (PARTICIPANTS WITH A GENETIC SPECIMEN)
Description

LEDRARWI

Data type

text

DRUSEN CATEGORY LT EYE (PARTICIPANTS WITH A GENETIC SPECIMEN)
Description

LEELICAT

Data type

text

PARTICIPANT DRUSEN CATEGORY (WORSE EYE; ALL PARTICIPANTS WITH A GENETICS SPECIMEN)
Description

DRUCAT

Data type

text

AMD SEVERITY SCALE SCORE LT EYE (PARTICIPANTS WITH A GENETIC SPECIMEN)
Description

AMDSEVLE

Data type

text

AMD SEVERITY SCALE SCORE RT EYE (PARTICIPANTS WITH A GENETIC SPECIMEN)
Description

AMDSEVRE

Data type

text

AMD SIMPLE SCALE SCORE (PERSON; ALL PARTICIPANTS WITH A GENETICS SPECIMEN)
Description

SCALE

Data type

text

LAST FUNDUS PHOTO IN CLINICAL TRIAL (PARTICIPANTS WITH A GENETIC SPECIMEN)
Description

LASTCLINF

Data type

text

YEARS FROM RANDOMIZATION TO DATE OF FUNDUS PHOTO RT EYE (PARTICIPANTS WITH A GENETIC SPECIMEN)
Description

REPHTIME

Data type

float

YEARS FROM RANDOMIZATION TO DATE OF FUNDUS PHOTO LT EYE (PARTICIPANTS WITH A GENETIC SPECIMEN)
Description

LEPHTIME

Data type

float

IRIS PIGMENTATION RT EYE (PARTICIPANTS WITH A GENETIC SPECIMEN)
Description

REIRISCO

Data type

text

NUCLEAR COLOR RT EYE (PARTICIPANTS WITH A GENETIC SPECIMEN)
Description

RENUCCOL

Data type

text

NUCLEAR SCLEROSIS RT EYE (PARTICIPANTS WITH A GENETIC SPECIMEN)
Description

RENUCSCL

Data type

float

CORTICAL OPACITY W/IN 5 MM RT EYE (PARTICIPANTS WITH A GENETIC SPECIMEN)
Description

REPCTCOL

Data type

float

PSC OPACITY W/IN 5 MM RT EYE (PARTICIPANTS WITH A GENETIC SPECIMEN)
Description

REPCTPSC

Data type

float

CORTICAL OPACITY IN WHOLE FIELD RT EYE (PARTICIPANTS WITH A GENETIC SPECIMEN)
Description

REPCTCOA

Data type

float

IRIS PIGMENTATION LT EYE (PARTICIPANTS WITH A GENETIC SPECIMEN)
Description

LEIRISCO

Data type

text

NUCLEAR COLOR LT EYE (PARTICIPANTS WITH A GENETIC SPECIMEN)
Description

LENUCCOL

Data type

text

NUCLEAR SCLEROSIS LT EYE (PARTICIPANTS WITH A GENETIC SPECIMEN)
Description

LENUCSCL

Data type

float

CORTICAL OPACITY W/IN 5 MM LT EYE (PARTICIPANTS WITH A GENETIC SPECIMEN)
Description

LEPCTCOL

Data type

float

PSC OPACITY W/IN 5 MM LT EYE (PARTICIPANTS WITH A GENETIC SPECIMEN)
Description

LEPCTPSC

Data type

float

CORTICAL OPACITY IN WHOLE FIELD LT EYE (PARTICIPANTS WITH A GENETIC SPECIMEN)
Description

LEPCTCOA

Data type

float

NUCLEAR SCLEROSIS RT EYE - RESCALED (PARTICIPANTS WITH A GENETIC SPECIMEN)
Description

RENUCADJ

Data type

float

NUCLEAR SCLEROSIS LT EYE - RESCALED (PARTICIPANTS WITH A GENETIC SPECIMEN)
Description

LENUCADJ

Data type

float

YEARS FROM RANDOMIZATION TO DATE OF NEITZ PHOTO RT EYE (PARTICIPANTS WITH A GENETIC SPECIMEN)
Description

RENZTIME

Data type

float

YEARS FROM RANDOMIZATION TO DATE OF SLIT LAMP PHOTO RT EYE (PARTICIPANTS WITH A GENETIC SPECIMEN)
Description

RESLTIME

Data type

float

YEARS FROM RANDOMIZATION TO DATE OF NEITZ PHOTO LT EYE (PARTICIPANTS WITH A GENETIC SPECIMEN)
Description

LENZTIME

Data type

float

YEARS FROM RANDOMIZATION TO DATE OF SLIT LAMP PHOTO LT EYE (PARTICIPANTS WITH A GENETIC SPECIMEN)
Description

LESLTIME

Data type

float

LAST LENS PHOTO IN CLINICAL TRIAL (PARTICIPANTS WITH A GENETIC SPECIMEN)
Description

LASTCLINL

Data type

text

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Similar models

The data table (n=62) contains information only for AREDS participants who have a genetic specimen. A unique patient identifier (ID2 field) for these participants (to be found only in GENSPECPHENOTYPE [pht000001.v2.p1] and GENSPECFUNDUSLENS data tables) is included instead of the patient identifier used for data tables with all participants (ID field). Information about fundus and lens characteristics are included as follows - fundus: presence, type, and extent of drusen, presence/extent of RPE depigmentation, SSR (serous sensory retinal) detachments, subretinal hemorrhages, subretinal fibrosis, and geographic atrophy; lens: degree of nuclear sclerosis, cortical and posterior subcapsular opacities, and iris pigmentation. In addition, information on photocoagulation (PC) treatment for AMD is included as well as AMD Severity Scale Scores and AMD Simple Scale Scores calculated from the fundus data.

19 forms
  1. StudyEvent: SEV1
    1. The data table (n=142 variables) contains AMD and cataract phenotype information, medical history and socio-demographic information drawn from several data sets (e.g. enrollment_randomization, amdlensphenotype, followup), plus a unique patient identifier (ID2) for participants with a genetic specimen (to be found only in GENSPECPHENOTYPE and GENSPECFUNDUSLENS [pht000376] tables). Nuclear, cortical and posterior subcapsular opacity information is included for both eyes at baseline and end of study. Other disease information (e.g. diabetes, cancer, angina), medical information (e.g. BMI, blood pressure) and smoking status are also included annually throughout follow-up.
    2. The data table (n=12 variables) contains information about the occurrence of adverse events during the AREDS clinical trial, e.g. type of adverse event, severity, primary ICD9 code, outcome, potential relationship to study drug, timing, and treatment. Data were collected through the clinical trial and for the first 6 months of the natural history follow-up immediately after the clinical trial concluded. Note: In version 3, the ID has been replaced by ID2 identifier for all subjects.
    3. The data table (n=25 variables) contains detailed information about cataract phenotypes (n=23 variables) as well as final AMD phenotype (n=1 variable), and patient ID. Nuclear, cortical and posterior subcapsular opacity information is included for both eyes at baseline and end of study. Note: In version 3, the ID has been replaced by ID2 identifier for all subjects.
    4. The data table (n=56 variables) contains information about AREDS participants' dietary intake of alcohol, amino acids, carbohydrates, fiber, poly- and monounsaturated fatty acids, proteins, vitamins and minerals. Participants' glycemic index and glycemic load are also included. Note: In version 3, the ID has been replaced by ID2 identifier for all subjects.
    5. The data table (n=102 variables) contains AREDS treatment assignment, basic socio-demographic characteristics and baseline medical history for AREDS participants. Medical history information includes eye disease information such as AMD Category, visual acuity, and past ophthalmic treatments (e.g. cataract surgery, laser treatment), as well as information about the presence/absence of other diseases (e.g. angina, arthritis, cancer, diabetes, high blood pressure), use of prescribed drugs for disease management (e.g. blood-thinning medications, digoxin, thyroid hormones, insulin), use of over-the-counter drugs (e.g. NSAIDs, antacids), intake of vitamins and minerals, and smoking history. Note: In version 3, the ID has been replaced by ID2 identifier for all subjects.
    6. The data table (n=83 variables) contains information obtained at follow-up visits during the AREDS clinical trial (every six months following randomization), annually in person during the natural history follow-up, and via phone between annual in-person visits. Variables include information about AREDS participants' ophthalmic medical history (e.g. cataract or other eye surgery, laser treatment for AMD, retinal repair, capsulotomy, presence/absence of lens, glaucoma, and visual acuity) and general medical information, including new diagnoses of cancer, heart disease, stroke, and peripheral vascular disease, disease history of angina and high blood pressure, current disease status of diabetes, arthritis, and gout, use of prescribed drugs for disease treatment or management (e.g. blood-thinning medications, digoxin, thyroid hormones, insulin), use of over-the-counter drugs (e.g. NSAIDs, antacids), and smoking behavior. For version 3 release of the study, visual acuity data of the right eye have been added for odd-numbered visits. Note: In version 3, the ID has been replaced by ID2 identifier for all subjects.
    7. The data table (n=49 variables) contains information from AREDS participants' fundus photographs, including presence, type, and extent of drusen, presence/extent of RPE depigmentation, SSR (serous sensory retinal) detachments, subretinal hemorrhages, subretinal fibrosis, and geographic atrophy. In addition, information on photocoagulation (PC) treatment for AMD SRNV is included, as well as AMD Severity Scale Scores and AMD Simple Scale Scores calculated from the fundus data. Note: In version 3, the ID has been replaced by ID2 identifier for all subjects.
    8. The data table (n=62) contains information only for AREDS participants who have a genetic specimen. A unique patient identifier (ID2 field) for these participants (to be found only in GENSPECPHENOTYPE [pht000001.v2.p1] and GENSPECFUNDUSLENS data tables) is included instead of the patient identifier used for data tables with all participants (ID field). Information about fundus and lens characteristics are included as follows - fundus: presence, type, and extent of drusen, presence/extent of RPE depigmentation, SSR (serous sensory retinal) detachments, subretinal hemorrhages, subretinal fibrosis, and geographic atrophy; lens: degree of nuclear sclerosis, cortical and posterior subcapsular opacities, and iris pigmentation. In addition, information on photocoagulation (PC) treatment for AMD is included as well as AMD Severity Scale Scores and AMD Simple Scale Scores calculated from the fundus data.
    9. The data table (n=6 variables) contains information about AREDS participant hospitalizations (e.g. reason, time from randomization, duration, primary ICD9 code) during the entire study. Note: In version 3, the ID has been replaced by ID2 identifier for all subjects.
    10. The data table (n=21 variables) contains information from AREDS participants' lens photographs, including degree of nuclear sclerosis, cortical and posterior subcapsular opacities, and iris pigmentation. Note: In version 3, the ID has been replaced by ID2 identifier for all subjects.
    11. The data table (n=7 variables) contains information about AREDS participant deaths (e.g. cause, time from randomization) during the entire study. A search using the National Death Index (NDI) yielded additional deaths not identified during the study. Note: In version 3, the ID has been replaced by ID2 identifier for all subjects.
    12. The data table (n=44 variables) contains information about AREDS participants' use (e.g. type, frequency, dose, duration) of non-steroidal anti-inflammatory drugs (e.g. aspirin, ibuprofen, acetaminophen, naproxen). Data were collected at in-clinic visits starting in October 2004. Note: In version 3, the ID has been replaced by ID2 identifier for all subjects.
    13. The data table (n=16 variables) contains information about AREDS participants' general vision status (e.g. general vision score, ocular pain score, VFQ overall score), and its effect on participants' behavior (e.g. near and distant activities, social activities, driving, mental health score) as obtained through the VFQ-25 questionnaire. Note: In version 3, the ID has been replaced by ID2 identifier for all subjects.
    14. Subject - Consent Information
    15. Subject - Sample Mapping (including mapping to Coriell IDs)
    16. The data table (n=2 variables) contains information on subjects' annual exposure to sunlight (hours; April through September).
    17. This dataset provides refractive error values obtained from control subjects of the AREDS study (phs000001.v3.p1) and represents a substudy of AREDS ; data of n=7 new variables are provided in addition to basic sociodemographic data. Subject - consent and subject - sample mapping information is available through phs000001.v3.p1.
    18. This dataset provides refractive error values obtained from control subjects of the AREDS study (phs000001.v3.p1) and represents a substudy of AREDS ; data of n=7 new variables are provided in addition to basic sociodemographic data. Subject - consent and subject - sample mapping information is available through phs000001.v3.p1.
    19. This dataset provides refractive error values obtained from control subjects of the AREDS study (phs000001.v3.p1) and represents a substudy of AREDS ; data of n=7 new variables are provided in addition to basic sociodemographic data. Subject - consent and subject - sample mapping information is available through phs000001.v3.p1.
Name
Type
Description | Question | Decode (Coded Value)
Data type
Alias
Item Group
pht000376.v1.p1
ID2
Item
DUMMY ID NUMBER (EYE DISEASE RESEARCH ONLY PARTICIPANTS HAVE A DIFFERENT DUMMY ID NUMBER)
string
Item
STUDY VISIT NUMBER (PARTICIPANTS WITH A GENETIC SPECIMEN)
text
VISNO
Code List
STUDY VISIT NUMBER (PARTICIPANTS WITH A GENETIC SPECIMEN)
CL Item
Baseline visit (00)
CL Item
0.5-year (01)
CL Item
1-year (02)
CL Item
1.5-years (03)
CL Item
2-years (04)
CL Item
2.5-years (05)
CL Item
3-years (06)
CL Item
3.5-years (07)
CL Item
4-years (08)
CL Item
4.5-years (09)
CL Item
5-years (10)
CL Item
5.5-years (11)
CL Item
6-years (12)
CL Item
6.5-years (13)
CL Item
7-years (14)
CL Item
7.5-years (15)
CL Item
8-years (16)
CL Item
8.5-years (17)
CL Item
9-years (18)
CL Item
9.5-years (19)
CL Item
10-years (20)
CL Item
10.5-years (21)
CL Item
11-years (22)
CL Item
11.5-years (23)
CL Item
12-years (24)
CL Item
12.5-years (25)
CL Item
13-years (26)
Item
DRUSENOID PED FIELD 2 RT EYE (PARTICIPANTS WITH A GENETIC SPECIMEN)
text
REDRUSF2
Code List
DRUSENOID PED FIELD 2 RT EYE (PARTICIPANTS WITH A GENETIC SPECIMEN)
CL Item
None (0)
CL Item
Questionable (1)
CL Item
Yes (2)
CL Item
Cannot grade (8)
Item
NON-DRUSENOID PED FIELD 2 RT EYE (PARTICIPANTS WITH A GENETIC SPECIMEN)
text
RENDRUF2
Code List
NON-DRUSENOID PED FIELD 2 RT EYE (PARTICIPANTS WITH A GENETIC SPECIMEN)
CL Item
None (0)
CL Item
Questionable (1)
CL Item
Yes (2)
CL Item
Cannot grade (8)
Item
SSR/HEMORRHAGIC RD FIELD 2 RT EYE (PARTICIPANTS WITH A GENETIC SPECIMEN)
text
RESSRF2
Code List
SSR/HEMORRHAGIC RD FIELD 2 RT EYE (PARTICIPANTS WITH A GENETIC SPECIMEN)
CL Item
None (0)
CL Item
Questionable (1)
CL Item
Yes (2)
CL Item
Cannot grade (8)
Item
HARD EXUDATE FIELD 2 RT EYE (PARTICIPANTS WITH A GENETIC SPECIMEN)
text
REHDEXF2
Code List
HARD EXUDATE FIELD 2 RT EYE (PARTICIPANTS WITH A GENETIC SPECIMEN)
CL Item
None (0)
CL Item
Questionable (1)
CL Item
Yes (2)
CL Item
Cannot grade (8)
Item
SUBRETINAL/SUBRPE HEMORRHAGE FIELD 2 RT EYE (PARTICIPANTS WITH A GENETIC SPECIMEN)
text
RESUBHF2
Code List
SUBRETINAL/SUBRPE HEMORRHAGE FIELD 2 RT EYE (PARTICIPANTS WITH A GENETIC SPECIMEN)
CL Item
None (0)
CL Item
Questionable (1)
CL Item
Yes (2)
CL Item
Cannot grade (8)
Item
SUBRETINAL FIBROSIS FIELD 2 RT EYE (PARTICIPANTS WITH A GENETIC SPECIMEN)
text
RESUBFF2
Code List
SUBRETINAL FIBROSIS FIELD 2 RT EYE (PARTICIPANTS WITH A GENETIC SPECIMEN)
CL Item
None (0)
CL Item
Questionable (1)
CL Item
Yes (2)
CL Item
Cannot grade (8)
Item
PC/AMD FIELD 2 RT EYE (PARTICIPANTS WITH A GENETIC SPECIMEN)
text
REPHCOF2
Code List
PC/AMD FIELD 2 RT EYE (PARTICIPANTS WITH A GENETIC SPECIMEN)
CL Item
None (0)
CL Item
Questionable (1)
CL Item
Yes (2)
CL Item
Cannot grade (8)
Item
GEOGRAPHIC ATROPHY CENTER POINT RT EYE (PARTICIPANTS WITH A GENETIC SPECIMEN)
text
REGEOACT
Code List
GEOGRAPHIC ATROPHY CENTER POINT RT EYE (PARTICIPANTS WITH A GENETIC SPECIMEN)
CL Item
None (0)
CL Item
Questionable (1)
CL Item
Definite, less than Circle I2 (diameter, 0.241 DD; area, 0.058 DA) (2)
CL Item
Cannot Grade (8)
Item
GEOGRAPHIC ATROPHY AREA C/SUB RT EYE (PARTICIPANTS WITH A GENETIC SPECIMEN)
text
REGEOACS
Code List
GEOGRAPHIC ATROPHY AREA C/SUB RT EYE (PARTICIPANTS WITH A GENETIC SPECIMEN)
CL Item
None (0)
CL Item
Questionable (1)
CL Item
Definite, less than Circle I2 (diameter, 0.241 DD; area, 0.058 DA) (2)
CL Item
Definite, more than or equal to Circle I2 (diameter, 0.241 DD; area, 0.058 DA), less than Circle O2 (diameter, 0.439 DD; area, 0.19 DA) (3)
CL Item
Definite, more than or equal to Circle O2 (diameter, 0.439 DD; area, 0.19 DA), less than 0.5 DA in area (diameter, 0.707 DD) (4)
CL Item
Cannot Grade (8)
Item
GEOGRAPHIC ATROPHY W/I GRID RT EYE (PARTICIPANTS WITH A GENETIC SPECIMEN)
text
REGEOAWI
Code List
GEOGRAPHIC ATROPHY W/I GRID RT EYE (PARTICIPANTS WITH A GENETIC SPECIMEN)
CL Item
None (0)
CL Item
Questionable (1)
CL Item
Definite, less than Circle I2 (diameter, 0.241 DD; area, 0.058 DA) (2)
CL Item
Definite, more than or equal to Circle I2 (diameter, 0.241 DD; area, 0.058 DA), less than Circle O2 (diameter, 0.439 DD; area, 0.19 DA) (3)
CL Item
Definite, more than or equal to Circle O2 (diameter, 0.439 DD; area, 0.19 DA), less than 0.5 DA in area (diameter, 0.707 DD) (4)
CL Item
Definite, more than or equal to 0.5 DA in area (diameter, 0.707 DD), less than 1 DA in area (diameter, 1.000 DD) (5)
CL Item
Definite, more than or equal to 1.0 DA in area (diameter, 1.000 DD), less than 2 DA in area (diameter, 1.414 DD) (6)
CL Item
Definite, more than or equal to 2.0 DA in area (diameter, 1.414 DD) (7)
CL Item
Cannot Grade (8)
Item
RPE DEPIGMENTATION AREA C/SUB+INNERS RT EYE (PARTICIPANTS WITH A GENETIC SPECIMEN)
text
RERPEDCI
Code List
RPE DEPIGMENTATION AREA C/SUB+INNERS RT EYE (PARTICIPANTS WITH A GENETIC SPECIMEN)
CL Item
None (0)
CL Item
Questionable (1)
CL Item
Definite, less than Circle I2 (diameter, 0.241 DD; area, 0.058 DA) (2)
CL Item
Definite, more than or equal to Circle I2 (diameter, 0.241 DD; area, 0.058 DA), less than Circle O2 (diameter, 0.439 DD; area, 0.19 DA) (3)
CL Item
Definite, more than or equal to Circle O2 (diameter, 0.439 DD; area, 0.19 DA), less than 0.5 DA in area (diameter, 0.707 DD) (4)
CL Item
Definite, more than or equal to 0.5 DA in area (diameter, 0.707 DD), less than 1 DA in area (diameter, 1.000 DD) (5)
CL Item
Definite, more than or equal to 1.0 DA in area (diameter, 1.000 DD), less than 2 DA in area (diameter, 1.414 DD) (6)
CL Item
Definite, more than or equal to 2.0 DA in area (diameter, 1.414 DD) (7)
CL Item
Cannot Grade (8)
Item
RPE DEPIGMENTATION AREA W/I GRID RT EYE (PARTICIPANTS WITH A GENETIC SPECIMEN)
text
RERPEDWI
Code List
RPE DEPIGMENTATION AREA W/I GRID RT EYE (PARTICIPANTS WITH A GENETIC SPECIMEN)
CL Item
None (0)
CL Item
Questionable (1)
CL Item
Definite, less than Circle I2 (diameter, 0.241 DD; area, 0.058 DA) (2)
CL Item
Definite, more than or equal to Circle I2 (diameter, 0.241 DD; area, 0.058 DA), less than Circle O2 (diameter, 0.439 DD; area, 0.19 DA) (3)
CL Item
Definite, more than or equal to Circle O2 (diameter, 0.439 DD; area, 0.19 DA), less than 0.5 DA in area (diameter, 0.707 DD) (4)
CL Item
Definite, more than or equal to 0.5 DA in area (diameter, 0.707 DD), less than 1 DA in area (diameter, 1.000 DD) (5)
CL Item
Definite, more than or equal to 1.0 DA in area (diameter, 1.000 DD), less than 2 DA in area (diameter, 1.414 DD) (6)
CL Item
Definite, more than or equal to 2.0 DA in area (diameter, 1.414 DD) (7)
CL Item
Cannot Grade (8)
Item
INCREASED PIGMENT AREA C/SUB+INNERS RT EYE (PARTICIPANTS WITH A GENETIC SPECIMEN)
text
REINCPCI
Code List
INCREASED PIGMENT AREA C/SUB+INNERS RT EYE (PARTICIPANTS WITH A GENETIC SPECIMEN)
CL Item
None (0)
CL Item
Questionable (1)
CL Item
Definite, less than Circle C0 (diameter, 0.042 DD; area, 0.0017 DA) (2)
CL Item
Definite, more than or equal to Circle C0 (diameter, 0.042 DD; area, 0.0017 DA), less than Circle C1 (diameter, 0.083 DD; area, 0.0069 DA) (3)
CL Item
Definite, more than or equal to Circle C1 (diameter, 0.083 DD; area, 0.0069 DA), less than Circle C2 (diameter, 0.167 DD; area, 0.028 DA) (4)
CL Item
Definite, more than or equal to Circle C2 (diameter, 0.167 DD; area, 0.028 DA), less than Circle O2 (diameter, 0.439 DD; area, 0.19 DA) (5)
CL Item
Definite, more than or equal to Circle O2 (diameter, 0.439 DD; area, 0.19 DA) (6)
CL Item
Other (7)
CL Item
Cannot Grade (8)
Item
INCREASED PIGMENT AREA W/I GRID RT EYE (PARTICIPANTS WITH A GENETIC SPECIMEN)
text
REINCPWI
Code List
INCREASED PIGMENT AREA W/I GRID RT EYE (PARTICIPANTS WITH A GENETIC SPECIMEN)
CL Item
None (0)
CL Item
Questionable (1)
CL Item
Definite, less than Circle C0 (diameter, 0.042 DD; area, 0.0017 DA) (2)
CL Item
Definite, more than or equal to Circle C0 (diameter, 0.042 DD; area, 0.0017 DA), less than Circle C1 (diameter, 0.083 DD; area, 0.0069 DA) (3)
CL Item
Definite, more than or equal to Circle C1 (diameter, 0.083 DD; area, 0.0069 DA), less than Circle C2 (diameter, 0.167 DD; area, 0.028 DA) (4)
CL Item
Definite, more than or equal to Circle C2 (diameter, 0.167 DD; area, 0.028 DA), less than Circle O2 (diameter, 0.439 DD; area, 0.19 DA) (5)
CL Item
Definite, more than or equal to Circle O2 (diameter, 0.439 DD; area, 0.19 DA) (6)
CL Item
Other (7)
CL Item
Cannot Grade (8)
Item
MAXIMUM DRUSEN SIZE W/I GRID RT EYE (PARTICIPANTS WITH A GENETIC SPECIMEN)
text
REDRSZWI
Code List
MAXIMUM DRUSEN SIZE W/I GRID RT EYE (PARTICIPANTS WITH A GENETIC SPECIMEN)
CL Item
None (0)
CL Item
Questionable (1)
CL Item
Definite, less than Circle C0 (63 microns) (2)
CL Item
Definite, more than or equal to Circle C0 (63 microns), less than Circle C1 (125 microns) (3)
CL Item
Definite, more than or equal to Circle C1 (125 microns), less than Circle C2 (250 microns) (4)
CL Item
Definite, more than or equal to Circle C2 (250 microns) (5)
CL Item
Cannot grade (8)
Item
DRUSEN AREA W/I GRID (PARTICIPANTS WITH A GENETIC SPECIMEN)
text
REDRARWI
Code List
DRUSEN AREA W/I GRID (PARTICIPANTS WITH A GENETIC SPECIMEN)
CL Item
None/Questionable/<Circle C0 (diameter, 0.042 DD; area, 0.0017 DA) (0)
CL Item
Definite, more than or equal to Circle C0 (diameter, 0.042 DD; area, 0.0017 DA), less than Circle C1 (diameter, 0.083 DD; area, 0.0069 DA) (1)
CL Item
Definite, more than or equal to Circle C1 (diameter, 0.083 DD; area, 0.0069 DA), less than Circle C2 (diameter, 0.167 DD; area, 0.028 DA) (2)
CL Item
Definite, more than or equal to Circle C2 (diameter, 0.167 DD; area, 0.028 DA), less than Circle I2 (diameter, 0.241 DD; area, 0.058 DA) (3)
CL Item
Definite, more than or equal to Circle I2 (diameter, 0.241 DD; area, 0.058 DA), less than Circle O2 (diameter, 0.439 DD; area, 0.19 DA) (4)
CL Item
Definite, more than or equal to Circle O2 (diameter, 0.439 DD; area, 0.19 DA), less than 0.5 DA in area (diameter, 0.707 DD) (5)
CL Item
Definite, more than or equal to 0.5 DA in area (diameter, 0.707 DD), less than 1 DA in area (diameter, 1.0 DD) (6)
CL Item
Definite, more than or equal to 1.0 DA in area (diameter, 1.0 DD) (7)
CL Item
Cannot Grade (8)
CL Item
End Stage (9)
Item
DRUSEN CATEGORY RT EYE (PARTICIPANTS WITH A GENETIC SPECIMEN)
text
REELICAT
Code List
DRUSEN CATEGORY RT EYE (PARTICIPANTS WITH A GENETIC SPECIMEN)
CL Item
Category 1 (1)
CL Item
Category 2 (2)
CL Item
Category 3 (3)
CL Item
Category 4 (4)
CL Item
Disqualifying lesion (visno=00 only) (5)
CL Item
Cannot grade (8)
Item
DRUSENOID PED FIELD 2 LT EYE (PARTICIPANTS WITH A GENETIC SPECIMEN)
text
LEDRUSF2
Code List
DRUSENOID PED FIELD 2 LT EYE (PARTICIPANTS WITH A GENETIC SPECIMEN)
CL Item
None (0)
CL Item
Questionable (1)
CL Item
Yes (2)
CL Item
Cannot grade (8)
Item
NON-DRUSENOID PED FIELD 2 LT EYE (PARTICIPANTS WITH A GENETIC SPECIMEN)
text
LENDRUF2
Code List
NON-DRUSENOID PED FIELD 2 LT EYE (PARTICIPANTS WITH A GENETIC SPECIMEN)
CL Item
None (0)
CL Item
Questionable (1)
CL Item
Yes (2)
CL Item
Cannot grade (8)
Item
SSR/HEMORRHAGIC RD FIELD 2 RT EYE (PARTICIPANTS WITH A GENETIC SPECIMEN)
text
LESSRF2
Code List
SSR/HEMORRHAGIC RD FIELD 2 RT EYE (PARTICIPANTS WITH A GENETIC SPECIMEN)
CL Item
None (0)
CL Item
Questionable (1)
CL Item
Yes (2)
CL Item
Cannot grade (8)
Item
HARD EXUDATE FIELD 2 LT EYE (PARTICIPANTS WITH A GENETIC SPECIMEN)
text
LEHDEXF2
Code List
HARD EXUDATE FIELD 2 LT EYE (PARTICIPANTS WITH A GENETIC SPECIMEN)
CL Item
None (0)
CL Item
Questionable (1)
CL Item
Yes (2)
CL Item
Cannot grade (8)
Item
SUBRETINAL/SUBRPE HEMORRHAGE FIELD 2 LT EYE (PARTICIPANTS WITH A GENETIC SPECIMEN)
text
LESUBHF2
Code List
SUBRETINAL/SUBRPE HEMORRHAGE FIELD 2 LT EYE (PARTICIPANTS WITH A GENETIC SPECIMEN)
CL Item
None (0)
CL Item
Questionable (1)
CL Item
Yes (2)
CL Item
Cannot grade (8)
Item
SUBRETINAL FIBROSIS FIELD 2 LT EYE (PARTICIPANTS WITH A GENETIC SPECIMEN)
text
LESUBFF2
Code List
SUBRETINAL FIBROSIS FIELD 2 LT EYE (PARTICIPANTS WITH A GENETIC SPECIMEN)
CL Item
None (0)
CL Item
Questionable (1)
CL Item
Yes (2)
CL Item
Cannot grade (8)
Item
PC/AMD FIELD 2 LT EYE (PARTICIPANTS WITH A GENETIC SPECIMEN)
text
LEPHCOF2
Code List
PC/AMD FIELD 2 LT EYE (PARTICIPANTS WITH A GENETIC SPECIMEN)
CL Item
None (0)
CL Item
Questionable (1)
CL Item
Yes (2)
CL Item
Cannot grade (8)
Item
GEOGRAPHIC ATROPHY CENTER POINT LT EYE (PARTICIPANTS WITH A GENETIC SPECIMEN)
text
LEGEOACT
Code List
GEOGRAPHIC ATROPHY CENTER POINT LT EYE (PARTICIPANTS WITH A GENETIC SPECIMEN)
CL Item
None (0)
CL Item
Questionable (1)
CL Item
Definite, less than Circle I2 (diameter, 0.241 DD; area, 0.058 DA) (2)
CL Item
Cannot Grade (8)
Item
GEOGRAPHIC ATROPHY AREA C/SUB LT EYE (PARTICIPANTS WITH A GENETIC SPECIMEN)
text
LEGEOACS
Code List
GEOGRAPHIC ATROPHY AREA C/SUB LT EYE (PARTICIPANTS WITH A GENETIC SPECIMEN)
CL Item
None (0)
CL Item
Questionable (1)
CL Item
Definite, less than Circle I2 (diameter, 0.241 DD; area, 0.058 DA) (2)
CL Item
Definite, more than or equal to Circle I2 (diameter, 0.241 DD; area, 0.058 DA), less than Circle O2 (diameter, 0.439 DD; area, 0.19 DA) (3)
CL Item
Definite, more than or equal to Circle O2 (diameter, 0.439 DD; area, 0.19 DA), less than 0.5 DA in area (diameter, 0.707 DD) (4)
CL Item
Cannot Grade (8)
Item
GEOGRAPHIC ATROPHY W/I GRID LT EYE (PARTICIPANTS WITH A GENETIC SPECIMEN)
text
LEGEOAWI
Code List
GEOGRAPHIC ATROPHY W/I GRID LT EYE (PARTICIPANTS WITH A GENETIC SPECIMEN)
CL Item
None (0)
CL Item
Questionable (1)
CL Item
Definite, less than Circle I2 (diameter, 0.241 DD; area, 0.058 DA) (2)
CL Item
Definite, more than or equal to Circle I2 (diameter, 0.241 DD; area, 0.058 DA), less than Circle O2 (diameter, 0.439 DD; area, 0.19 DA) (3)
CL Item
Definite, more than or equal to Circle O2 (diameter, 0.439 DD; area, 0.19 DA), less than 0.5 DA in area (diameter, 0.707 DD) (4)
CL Item
Definite, more than or equal to 0.5 DA in area (diameter, 0.707 DD), less than 1 DA in area (diameter, 1.000 DD) (5)
CL Item
Definite, more than or equal to 1.0 DA in area (diameter, 1.000 DD), less than 2 DA in area (diameter, 1.414 DD) (6)
CL Item
Definite, more than or equal to 2.0 DA in area (diameter, 1.414 DD) (7)
CL Item
Cannot Grade (8)
Item
RPE DEPIGMENTATION AREA C/SUB+INNERS LT EYE (PARTICIPANTS WITH A GENETIC SPECIMEN)
text
LERPEDCI
Code List
RPE DEPIGMENTATION AREA C/SUB+INNERS LT EYE (PARTICIPANTS WITH A GENETIC SPECIMEN)
CL Item
None (0)
CL Item
Questionable (1)
CL Item
Definite, less than Circle I2 (diameter, 0.241 DD; area, 0.058 DA) (2)
CL Item
Definite, more than or equal to Circle I2 (diameter, 0.241 DD; area, 0.058 DA), less than Circle O2 (diameter, 0.439 DD; area, 0.19 DA) (3)
CL Item
Definite, more than or equal to Circle O2 (diameter, 0.439 DD; area, 0.19 DA), less than 0.5 DA in area (diameter, 0.707 DD) (4)
CL Item
Definite, more than or equal to 0.5 DA in area (diameter, 0.707 DD), less than 1 DA in area (diameter, 1.000 DD) (5)
CL Item
Definite, more than or equal to 1.0 DA in area (diameter, 1.000 DD), less than 2 DA in area (diameter, 1.414 DD) (6)
CL Item
Definite, more than or equal to 2.0 DA in area (diameter, 1.414 DD) (7)
CL Item
Cannot Grade (8)
Item
RPE DEPIGMENTATION AREA W/I GRID LT EYE (PARTICIPANTS WITH A GENETIC SPECIMEN)
text
LERPEDWI
Code List
RPE DEPIGMENTATION AREA W/I GRID LT EYE (PARTICIPANTS WITH A GENETIC SPECIMEN)
CL Item
None (0)
CL Item
Questionable (1)
CL Item
Definite, less than Circle I2 (diameter, 0.241 DD; area, 0.058 DA) (2)
CL Item
Definite, more than or equal to Circle I2 (diameter, 0.241 DD; area, 0.058 DA), less than Circle O2 (diameter, 0.439 DD; area, 0.19 DA) (3)
CL Item
Definite, more than or equal to Circle O2 (diameter, 0.439 DD; area, 0.19 DA), less than 0.5 DA in area (diameter, 0.707 DD) (4)
CL Item
Definite, more than or equal to 0.5 DA in area (diameter, 0.707 DD), less than 1 DA in area (diameter, 1.000 DD) (5)
CL Item
Definite, more than or equal to 1.0 DA in area (diameter, 1.000 DD), less than 2 DA in area (diameter, 1.414 DD) (6)
CL Item
Definite, more than or equal to 2.0 DA in area (diameter, 1.414 DD) (7)
CL Item
Cannot Grade (8)
Item
INCREASED PIGMENT AREA C/SUB+INNERS LT EYE (PARTICIPANTS WITH A GENETIC SPECIMEN)
text
LEINCPCI
Code List
INCREASED PIGMENT AREA C/SUB+INNERS LT EYE (PARTICIPANTS WITH A GENETIC SPECIMEN)
CL Item
None (0)
CL Item
Questionable (1)
CL Item
Definite, less than Circle C0 (diameter, 0.042 DD; area, 0.0017 DA) (2)
CL Item
Definite, more than or equal to Circle C0 (diameter, 0.042 DD; area, 0.0017 DA), less than Circle C1 (diameter, 0.083 DD; area, 0.0069 DA) (3)
CL Item
Definite, more than or equal to Circle C1 (diameter, 0.083 DD; area, 0.0069 DA), less than Circle C2 (diameter, 0.167 DD; area, 0.028 DA) (4)
CL Item
Definite, more than or equal to Circle C2 (diameter, 0.167 DD; area, 0.028 DA), less than Circle O2 (diameter, 0.439 DD; area, 0.19 DA) (5)
CL Item
Definite, more than or equal to Circle O2 (diameter, 0.439 DD; area, 0.19 DA) (6)
CL Item
Other (7)
CL Item
Cannot Grade (8)
Item
INCREASED PIGMENT AREA W/I GRID LT EYE (PARTICIPANTS WITH A GENETIC SPECIMEN)
text
LEINCPWI
Code List
INCREASED PIGMENT AREA W/I GRID LT EYE (PARTICIPANTS WITH A GENETIC SPECIMEN)
CL Item
None (0)
CL Item
Questionable (1)
CL Item
Definite, less than Circle I2 (diameter, 0.241 DD; area, 0.058 DA) (2)
CL Item
Definite, more than or equal to Circle I2 (diameter, 0.241 DD; area, 0.058 DA), less than Circle O2 (diameter, 0.439 DD; area, 0.19 DA) (3)
CL Item
Definite, more than or equal to Circle O2 (diameter, 0.439 DD; area, 0.19 DA), less than 0.5 DA in area (diameter, 0.707 DD) (4)
CL Item
Definite, more than or equal to 0.5 DA in area (diameter, 0.707 DD), less than 1 DA in area (diameter, 1.000 DD) (5)
CL Item
Definite, more than or equal to 1.0 DA in area (diameter, 1.000 DD), less than 2 DA in area (diameter, 1.414 DD) (6)
CL Item
Definite, more than or equal to 2.0 DA in area (diameter, 1.414 DD) (7)
CL Item
Cannot Grade (8)
Item
MAXIMUM DRUSEN SIZE W/I GRID LT EYE (PARTICIPANTS WITH A GENETIC SPECIMEN)
text
LEDRSZWI
Code List
MAXIMUM DRUSEN SIZE W/I GRID LT EYE (PARTICIPANTS WITH A GENETIC SPECIMEN)
CL Item
None (0)
CL Item
Questionable (1)
CL Item
Definite, less than Circle C0 (63 microns) (2)
CL Item
Definite, more than or equal to Circle C0 (63 microns), less than Circle C1 (125 microns) (3)
CL Item
Definite, more than or equal to Circle C1 (125 microns), less than Circle C2 (250 microns) (4)
CL Item
Definite, more than or equal to Circle C2 (250 microns) (5)
CL Item
Cannot grade (8)
Item
DRUSEN AREA W/I GRID LT EYE (PARTICIPANTS WITH A GENETIC SPECIMEN)
text
LEDRARWI
Code List
DRUSEN AREA W/I GRID LT EYE (PARTICIPANTS WITH A GENETIC SPECIMEN)
CL Item
None (0)
CL Item
Questionable (1)
CL Item
Definite, less than Circle I2 (diameter, 0.241 DD; area, 0.058 DA) (2)
CL Item
Definite, more than or equal to Circle I2 (diameter, 0.241 DD; area, 0.058 DA), less than Circle O2 (diameter, 0.439 DD; area, 0.19 DA) (3)
CL Item
Definite, more than or equal to Circle O2 (diameter, 0.439 DD; area, 0.19 DA), less than 0.5 DA in area (diameter, 0.707 DD) (4)
CL Item
Definite, more than or equal to 0.5 DA in area (diameter, 0.707 DD), less than 1 DA in area (diameter, 1.000 DD) (5)
CL Item
Definite, more than or equal to 1.0 DA in area (diameter, 1.000 DD), less than 2 DA in area (diameter, 1.414 DD) (6)
CL Item
Definite, more than or equal to 2.0 DA in area (diameter, 1.414 DD) (7)
CL Item
Cannot Grade (8)
CL Item
End stage (9)
Item
DRUSEN CATEGORY LT EYE (PARTICIPANTS WITH A GENETIC SPECIMEN)
text
LEELICAT
Code List
DRUSEN CATEGORY LT EYE (PARTICIPANTS WITH A GENETIC SPECIMEN)
CL Item
Category 1 (1)
CL Item
Category 2 (2)
CL Item
Category 3 (3)
CL Item
Category 4 (4)
CL Item
Disqualifying lesion (visno=00 only) (5)
CL Item
Cannot grade (8)
Item
PARTICIPANT DRUSEN CATEGORY (WORSE EYE; ALL PARTICIPANTS WITH A GENETICS SPECIMEN)
text
DRUCAT
Code List
PARTICIPANT DRUSEN CATEGORY (WORSE EYE; ALL PARTICIPANTS WITH A GENETICS SPECIMEN)
CL Item
Category 1 (both eyes) (1)
CL Item
Category 2 (2)
CL Item
Category 3 (3)
CL Item
Category 4 (one eye) (4)
CL Item
Category 4 (both eyes) (5)
CL Item
Cannot grade (8)
CL Item
Category 3a (3a)
CL Item
Category 3b (3b)
Item
AMD SEVERITY SCALE SCORE LT EYE (PARTICIPANTS WITH A GENETIC SPECIMEN)
text
AMDSEVLE
Code List
AMD SEVERITY SCALE SCORE LT EYE (PARTICIPANTS WITH A GENETIC SPECIMEN)
CL Item
Scale Step 1 (1)
CL Item
Scale Step 2 (2)
CL Item
Scale Step 3 (3)
CL Item
Scale Step 4 (4)
CL Item
Scale Step 5 (5)
CL Item
Scale Step 6 (6)
CL Item
Scale Step 7 (7)
CL Item
Scale Step 8 (8)
CL Item
Scale Step 9 (9)
CL Item
Central Geographic Atrophy (10)
CL Item
Neovascular AMD (11)
CL Item
Neovascular AMD and Central Geographic Atrophy (12)
Item
AMD SEVERITY SCALE SCORE RT EYE (PARTICIPANTS WITH A GENETIC SPECIMEN)
text
AMDSEVRE
Code List
AMD SEVERITY SCALE SCORE RT EYE (PARTICIPANTS WITH A GENETIC SPECIMEN)
CL Item
Scale Step 1 (1)
CL Item
Scale Step 2 (2)
CL Item
Scale Step 3 (3)
CL Item
Scale Step 4 (4)
CL Item
Scale Step 5 (5)
CL Item
Scale Step 6 (6)
CL Item
Scale Step 7 (7)
CL Item
Scale Step 8 (8)
CL Item
Scale Step 9 (9)
CL Item
Central Geographic Atrophy (10)
CL Item
Neovascular AMD (11)
CL Item
Neovascular AMD and Central Geographic Atrophy (12)
SCALE
Item
AMD SIMPLE SCALE SCORE (PERSON; ALL PARTICIPANTS WITH A GENETICS SPECIMEN)
text
Item
LAST FUNDUS PHOTO IN CLINICAL TRIAL (PARTICIPANTS WITH A GENETIC SPECIMEN)
text
LASTCLINF
Code List
LAST FUNDUS PHOTO IN CLINICAL TRIAL (PARTICIPANTS WITH A GENETIC SPECIMEN)
CL Item
Yes (Y)
REPHTIME
Item
YEARS FROM RANDOMIZATION TO DATE OF FUNDUS PHOTO RT EYE (PARTICIPANTS WITH A GENETIC SPECIMEN)
float
LEPHTIME
Item
YEARS FROM RANDOMIZATION TO DATE OF FUNDUS PHOTO LT EYE (PARTICIPANTS WITH A GENETIC SPECIMEN)
float
Item
IRIS PIGMENTATION RT EYE (PARTICIPANTS WITH A GENETIC SPECIMEN)
text
REIRISCO
Code List
IRIS PIGMENTATION RT EYE (PARTICIPANTS WITH A GENETIC SPECIMEN)
CL Item
Less than or equal to Std. 1 (1)
CL Item
Less than or equal to Std. 2 (2)
CL Item
Less than or equal to Std. 3 (3)
CL Item
More than Std. 3 (4)
CL Item
Cannot grade (8)
Item
NUCLEAR COLOR RT EYE (PARTICIPANTS WITH A GENETIC SPECIMEN)
text
RENUCCOL
Code List
NUCLEAR COLOR RT EYE (PARTICIPANTS WITH A GENETIC SPECIMEN)
CL Item
Less than or equal to Std. 2 (1)
CL Item
Less than or equal to Std. 4 (2)
CL Item
Less than or equal to Std. 8 (3)
CL Item
More than Std. 8 (4)
CL Item
Cannot grade (8)
RENUCSCL
Item
NUCLEAR SCLEROSIS RT EYE (PARTICIPANTS WITH A GENETIC SPECIMEN)
float
REPCTCOL
Item
CORTICAL OPACITY W/IN 5 MM RT EYE (PARTICIPANTS WITH A GENETIC SPECIMEN)
float
REPCTPSC
Item
PSC OPACITY W/IN 5 MM RT EYE (PARTICIPANTS WITH A GENETIC SPECIMEN)
float
REPCTCOA
Item
CORTICAL OPACITY IN WHOLE FIELD RT EYE (PARTICIPANTS WITH A GENETIC SPECIMEN)
float
Item
IRIS PIGMENTATION LT EYE (PARTICIPANTS WITH A GENETIC SPECIMEN)
text
LEIRISCO
Code List
IRIS PIGMENTATION LT EYE (PARTICIPANTS WITH A GENETIC SPECIMEN)
CL Item
Less than or equal to Std. 1 (1)
CL Item
Less than or equal to Std. 2 (2)
CL Item
Less than or equal to Std. 3 (3)
CL Item
More than Std. 3 (4)
CL Item
Cannot grade (8)
Item
NUCLEAR COLOR LT EYE (PARTICIPANTS WITH A GENETIC SPECIMEN)
text
LENUCCOL
Code List
NUCLEAR COLOR LT EYE (PARTICIPANTS WITH A GENETIC SPECIMEN)
CL Item
Less than or equal to Std. 2 (1)
CL Item
Less than or equal to Std. 4 (2)
CL Item
Less than or equal to Std. 8 (3)
CL Item
More than Std. 8 (4)
CL Item
Cannot grade (8)
LENUCSCL
Item
NUCLEAR SCLEROSIS LT EYE (PARTICIPANTS WITH A GENETIC SPECIMEN)
float
LEPCTCOL
Item
CORTICAL OPACITY W/IN 5 MM LT EYE (PARTICIPANTS WITH A GENETIC SPECIMEN)
float
LEPCTPSC
Item
PSC OPACITY W/IN 5 MM LT EYE (PARTICIPANTS WITH A GENETIC SPECIMEN)
float
LEPCTCOA
Item
CORTICAL OPACITY IN WHOLE FIELD LT EYE (PARTICIPANTS WITH A GENETIC SPECIMEN)
float
RENUCADJ
Item
NUCLEAR SCLEROSIS RT EYE - RESCALED (PARTICIPANTS WITH A GENETIC SPECIMEN)
float
LENUCADJ
Item
NUCLEAR SCLEROSIS LT EYE - RESCALED (PARTICIPANTS WITH A GENETIC SPECIMEN)
float
RENZTIME
Item
YEARS FROM RANDOMIZATION TO DATE OF NEITZ PHOTO RT EYE (PARTICIPANTS WITH A GENETIC SPECIMEN)
float
RESLTIME
Item
YEARS FROM RANDOMIZATION TO DATE OF SLIT LAMP PHOTO RT EYE (PARTICIPANTS WITH A GENETIC SPECIMEN)
float
LENZTIME
Item
YEARS FROM RANDOMIZATION TO DATE OF NEITZ PHOTO LT EYE (PARTICIPANTS WITH A GENETIC SPECIMEN)
float
LESLTIME
Item
YEARS FROM RANDOMIZATION TO DATE OF SLIT LAMP PHOTO LT EYE (PARTICIPANTS WITH A GENETIC SPECIMEN)
float
Item
LAST LENS PHOTO IN CLINICAL TRIAL (PARTICIPANTS WITH A GENETIC SPECIMEN)
text
LASTCLINL
Code List
LAST LENS PHOTO IN CLINICAL TRIAL (PARTICIPANTS WITH A GENETIC SPECIMEN)
CL Item
Yes (Y)
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