subject has a systolic blood pressure ≥ 140 mmhg based on an average of 3 office blood pressure readings measured according to the bp guidelines
Item
1. subject has a systolic blood pressure ≥ 140 mmhg based on an average of 3 office blood pressure readings measured according to the bp guidelines.
boolean
C0871470 (UMLS CUI [1,1])
C1522609 (UMLS CUI [1,2])
C0242485 (UMLS CUI [1,3])
C0031834 (UMLS CUI [1,4])
C0750480 (UMLS CUI [1,5])
C1510992 (UMLS CUI [1,6])
subject is adhering to a stable drug regimen of at least 3 different classes of anti-hypertensive medications, including a diuretic (with no changes for a minimum of 2 weeks prior to enrollment) at optimal dose and is expected to be maintained for at least 6 months
Item
2. subject is adhering to a stable drug regimen of at least 3 different classes of anti-hypertensive medications, including a diuretic (with no changes for a minimum of 2 weeks prior to enrollment) at optimal dose and is expected to be maintained for at least 6 months.
boolean
C0003364 (UMLS CUI [1,1])
C0750480 (UMLS CUI [1,2])
C0237125 (UMLS CUI [1,3])
C0205360 (UMLS CUI [1,4])
C1321605 (UMLS CUI [1,5])
C0012798 (UMLS CUI [1,6])
C0178602 (UMLS CUI [1,7])
C2698651 (UMLS CUI [1,8])
subject is > 18 and < 85 years of age
Item
3. subject is > 18 and < 85 years of age.
boolean
C0001779 (UMLS CUI [1])
subject agrees to have all study procedures performed, and is competent and willing to provide written, informed consent to participate in this study
Item
4. subject agrees to have all study procedures performed, and is competent and willing to provide written, informed consent to participate in this study.
boolean
C0021430 (UMLS CUI [1,1])
C0086035 (UMLS CUI [1,2])
C0600109 (UMLS CUI [1,3])
C0199171 (UMLS CUI [2,1])
C2347804 (UMLS CUI [2,2])
C0680240 (UMLS CUI [2,3])
a secondary cause of hypertension, e.g.
Item
1. a secondary cause of hypertension, e.g. "white coat" hypertension (assessed by 24 h abpm at physician's discretion), primary aldosteronism, pheochromocytoma, renal artery stenosis, drug induced-hypertension, adult polycystic kidney disease, renal cell carcinoma, pyelonephritis, glomerulonephritis, coarctation of the aorta, acromegaly, cushing's syndrome, conn's (primary hyperaldosteronism), polyarteritis nodosum, systemic sclerosis, parenchymal kidney disease, obstructive sleep apnoea based on a workup performed within the 12 months preceding enrollment.
boolean
C0155616 (UMLS CUI [1,1])
C0262534 (UMLS CUI [1,2])
C1282173 (UMLS CUI [1,3])
C1719312 (UMLS CUI [1,4])
C0031511 (UMLS CUI [1,5])
C0035067 (UMLS CUI [1,6])
C0020538 (UMLS CUI [1,7])
C0458082 (UMLS CUI [1,8])
C0022680 (UMLS CUI [1,9])
C0007134 (UMLS CUI [1,10])
C0034186 (UMLS CUI [1,11])
C0017658 (UMLS CUI [1,12])
C0003492 (UMLS CUI [1,13])
C0001206 (UMLS CUI [1,14])
C0010481 (UMLS CUI [1,15])
C1384514 (UMLS CUI [1,16])
C0031036 (UMLS CUI [1,17])
C0205373 (UMLS CUI [1,18])
C0036429 (UMLS CUI [1,19])
C0022658 (UMLS CUI [1,20])
C4277702 (UMLS CUI [1,21])
C0520679 (UMLS CUI [1,22])
subject has aorto-ilio-femoral artery anatomy not suitable for treatment with the investigational device(s)
Item
2. subject has aorto-ilio-femoral artery anatomy not suitable for treatment with the investigational device(s).
boolean
C0015801 (UMLS CUI [1,1])
C0700276 (UMLS CUI [1,2])
C1512714 (UMLS CUI [1,3])
C0087111 (UMLS CUI [1,4])
C2346570 (UMLS CUI [1,5])
subject has main renal arteries that are < 20 mm in length or < 4 mm in diameter
Item
3. subject has main renal arteries that are < 20 mm in length or < 4 mm in diameter.
boolean
C0035065 (UMLS CUI [1,1])
C1542147 (UMLS CUI [1,2])
C1444754 (UMLS CUI [1,3])
C1522609 (UMLS CUI [1,4])
C0035065 (UMLS CUI [2,1])
C1542147 (UMLS CUI [2,2])
C1301886 (UMLS CUI [2,3])
C1522609 (UMLS CUI [2,4])
subject has a prior history of any renal artery intervention including but not limited to balloon angioplasty, stenting , renal denervation or surgery
Item
4. subject has a prior history of any renal artery intervention including but not limited to balloon angioplasty, stenting , renal denervation or surgery.
boolean
C0262926 (UMLS CUI [1,1])
C0035065 (UMLS CUI [1,2])
C0184661 (UMLS CUI [1,3])
C0002996 (UMLS CUI [1,4])
C0038257 (UMLS CUI [1,5])
C3544270 (UMLS CUI [1,6])
C0543467 (UMLS CUI [1,7])
subject has an estimated glomerular filtration rate (egfr) of < 45ml/min/1.73m2, using the mdrd formula
Item
5. subject has an estimated glomerular filtration rate (egfr) of < 45ml/min/1.73m2, using the mdrd formula.
boolean
C3811844 (UMLS CUI [1,1])
C1522609 (UMLS CUI [1,2])
C3839656 (UMLS CUI [1,3])
subject has type 1 diabetes mellitus
Item
6. subject has type 1 diabetes mellitus.
boolean
C0011854 (UMLS CUI [1])
subject has history of myocardial infarction, unstable angina pectoris, or a cerebrovascular accident in the 6 months period prior to enrolment, or documented widespread atherosclerosis, intravascular thrombosis or unstable plaques
Item
7. subject has history of myocardial infarction, unstable angina pectoris, or a cerebrovascular accident in the 6 months period prior to enrolment, or documented widespread atherosclerosis, intravascular thrombosis or unstable plaques.
boolean
C0027051 (UMLS CUI [1,1])
C0332185 (UMLS CUI [1,2])
C0002965 (UMLS CUI [2,1])
C0332185 (UMLS CUI [2,2])
C0038454 (UMLS CUI [3,1])
C0332185 (UMLS CUI [3,2])
C0004153 (UMLS CUI [4,1])
C1301725 (UMLS CUI [4,2])
C0040053 (UMLS CUI [5,1])
C0442123 (UMLS CUI [5,2])
C1301725 (UMLS CUI [5,3])
C0332461 (UMLS CUI [6,1])
C0443343 (UMLS CUI [6,2])
C1301725 (UMLS CUI [6,3])
subject has hemodynamically significant valvular heart disease for which reduction of blood pressure would be considered hazardous
Item
8. subject has hemodynamically significant valvular heart disease for which reduction of blood pressure would be considered hazardous.
boolean
C0018824 (UMLS CUI [1,1])
C0019010 (UMLS CUI [1,2])
C0750502 (UMLS CUI [1,3])
C0005823 (UMLS CUI [1,4])
C0441610 (UMLS CUI [1,5])
C0035647 (UMLS CUI [1,6])