written informed consent
Item
patients must provide written informed consent
boolean
C0021430 (UMLS CUI [1])
eastern cooperative oncology group performance status
Item
eastern cooperative oncology group performance status of at least 1
boolean
C1520224 (UMLS CUI [1])
cytologically or histologically proven diagnosis of scc of the penis
Item
cytologically or histologically proven diagnosis of scc of the penis
boolean
C0030851 (UMLS CUI [1,1])
C0075091 (UMLS CUI [1,2])
C0205471 (UMLS CUI [1,3])
C0030851 (UMLS CUI [2,1])
C0075091 (UMLS CUI [2,2])
C0679557 (UMLS CUI [2,3])
uni- or bidimensionally measurable disease as defined by recist v1.1 criteria
Item
uni- or bidimensionally measurable disease as defined by recist v1.1 criteria
boolean
C0439534 (UMLS CUI [1,1])
C0205447 (UMLS CUI [1,2])
C1513041 (UMLS CUI [1,3])
C1709926 (UMLS CUI [1,4])
C0439534 (UMLS CUI [2,1])
C3844700 (UMLS CUI [2,2])
C1513041 (UMLS CUI [2,3])
C1709926 (UMLS CUI [2,4])
TNM clinical stage
Item
clinical stage n2-3 and/or m1 (tnm 2002)
boolean
C3258246 (UMLS CUI [1])
locoregional relapse after prior major surgery/ies
Item
locoregional relapse after prior major surgery/ies (either single or multiple)
boolean
C0744961 (UMLS CUI [1,1])
C0035020 (UMLS CUI [1,2])
C1947913 (UMLS CUI [1,3])
no prior systemic therapy except for vincristine-bleomycin-methotrexate chemotherapy
Item
no prior systemic therapy except for the administration of vincristine-bleomycin-methotrexate (vbm) chemotherapy for superficial disease if administered at least 6 months prior to study enrollment
boolean
C1883256 (UMLS CUI [1,1])
C0332197 (UMLS CUI [1,2])
C0078140 (UMLS CUI [1,3])
C0332185 (UMLS CUI [1,4])
C1705847 (UMLS CUI [1,5])
adequate bone marrow, liver and renal function
Item
adequate bone marrow, liver and renal function
boolean
C0005953 (UMLS CUI [1,1])
C0678852 (UMLS CUI [1,2])
C0205411 (UMLS CUI [1,3])
C0232741 (UMLS CUI [1,4])
C0232804 (UMLS CUI [1,5])
central nervous system (cns) metastases or leptomeningeal carcinomatosis
Item
central nervous system (cns) metastases or leptomeningeal carcinomatosis
boolean
C0279130 (UMLS CUI [1])
C0220654 (UMLS CUI [2])
history of cardiovascular, cerebrovascular, pulmonary co-morbidities
Item
history of active serious cardiovascular, cerebrovascular, pulmonary co-morbidities
boolean
C0262926 (UMLS CUI [1,1])
C0007222 (UMLS CUI [1,2])
C0262926 (UMLS CUI [2,1])
C0007820 (UMLS CUI [2,2])
C0262926 (UMLS CUI [3,1])
C0024115 (UMLS CUI [3,2])
previous or concurrent cancer
Item
previous or concurrent cancer that is distinct in primary site or histology from the cancer being evaluated in this study except cervical carcinoma in situ, treated basal cell carcinoma or any cancer curatively treated > 5 years prior to study entry.
boolean
C0006826 (UMLS CUI [1,1])
C0205156 (UMLS CUI [1,2])
C0006826 (UMLS CUI [2,1])
C0205420 (UMLS CUI [2,2])