age at least 18 Years
Item
Alter mindestens 18 Jahre
boolean
C0001779 (UMLS CUI 2011AA)
397669002 (SNOMED CT 2011_0131)
Patients with B-precursor ALL relapsed after at least induction and consolidation or having refractory disease
Item
Patients with B-precursor ALL relapsed after at least induction and consolidation or having refractory disease
boolean
C1292769 (UMLS CUI 2011AA)
128823009 (SNOMED CT 2011_0131)
10003890 (MedDRA 14.1)
C0011900 (UMLS CUI 2011AA)
439401001 (SNOMED CT 2011_0131)
MTHU008876 (LOINC Version 232)
C0277556 (UMLS CUI 2011AA)
58184002 (SNOMED CT 2011_0131)
C0600558 (UMLS CUI 2011AA)
C0702116 (UMLS CUI 2011AA)
9656002 (SNOMED CT 2011_0131)
C1514815 (UMLS CUI 2011AA)
More than 5% blasts in bone marrow
Item
More than 5% blasts in bone marrow
boolean
C0439093 (UMLS CUI 2011AA)
276140008 (SNOMED CT 2011_0131)
GT (HL7 V3 2006_05)
C0205451 (UMLS CUI 2011AA)
34001005 (SNOMED CT 2011_0131)
C0439165 (UMLS CUI 2011AA)
118582008 (SNOMED CT 2011_0131)
C0368761 (UMLS CUI 2011AA)
312256009 (SNOMED CT 2011_0131)
MTHU005201 (LOINC Version 232)
C0005953 (UMLS CUI 2011AA)
14016003 (SNOMED CT 2011_0131)
MTHU016536 (LOINC Version 232)
ECOG performance status <= 2
Item
ECOG Status <= 2
boolean
C1520224 (UMLS CUI 2011AA)
424122007 (SNOMED CT 2011_0131)
Life expectancy of >= 12 weeks
Item
Life expectancy of >= 12 weeks
boolean
C0023671 (UMLS CUI 2011AA)
History or presence of clinically relevant CNS pathology
Item
History or presence of clinically relevant CNS pathology
boolean
C0205210 (UMLS CUI 2011AA)
58147004 (SNOMED CT 2011_0131)
C2347946 (UMLS CUI 2011AA)
C1269563 (UMLS CUI 2011AA)
278199004 (SNOMED CT 2011_0131)
C0677042 (UMLS CUI 2011AA)
Infiltration of cerebrospinal fluid (CSF) by ALL
Item
Infiltration of cerebrospinal fluid (CSF) by ALL
boolean
C0332448 (UMLS CUI 2011AA)
47351003 (SNOMED CT 2011_0131)
C0007806 (UMLS CUI 2011AA)
65216001 (SNOMED CT 2011_0131)
MTHU001311 (LOINC Version 232)
CSF (HL7 V3 2006_05)
C0023449 (UMLS CUI 2011AA)
91857003, 128822004 (SNOMED CT 2011_0131)
10060390 (MedDRA 14.1)
C91.0 (ICD-10-CM Version 2010)
204.0 (ICD-9-CM Version 2011)
Autologous/allogeneic HSCT within six weeks/three months prior to start of blinatumomab treatment
Item
Autologous/allogeneic HSCT within six weeks/three months prior to start of blinatumomab treatment
boolean
C1831743 (UMLS CUI 2011AA)
C2242529 (UMLS CUI 2011AA)
10067862 (MedDRA 14.1)
C0205449 (UMLS CUI 2011AA)
421291004 (SNOMED CT 2011_0131)
C0439231 (UMLS CUI 2011AA)
258706009 (SNOMED CT 2011_0131)
MO (HL7 V3 2006_05)
C0332152 (UMLS CUI 2011AA)
288556008 (SNOMED CT 2011_0131)
C3853839 (UMLS CUI 2011AA)
C0039798 (UMLS CUI 2011AA)
Active Graft-versus-Host Disease (GvHD)
Item
Active Graft-versus-Host Disease (GvHD)
boolean
C0205177 (UMLS CUI 2011AA)
55561003 (SNOMED CT 2011_0131)
C0018133 (UMLS CUI 2011AA)
234646005 (SNOMED CT 2011_0131)
10018651 (MedDRA 14.1)
D89.813 (ICD-10-CM Version 2010)
279.50 (ICD-9-CM Version 2011)
Patients with Ph+ ALL eligible for treatment with dasatinib or imatinib
Item
Patients with Ph+ ALL eligible for treatment with dasatinib or imatinib
boolean
C1960397 (UMLS CUI 2011AA)
425688002 (SNOMED CT 2011_0131)
C1548635 (UMLS CUI 2011AA)
ELG (HL7 V3 2006_05)
C0039798 (UMLS CUI 2011AA)
C1455147 (UMLS CUI 2011AA)
422756008 (SNOMED CT 2011_0131)
C0935989 (UMLS CUI 2011AA)
391634008 (SNOMED CT 2011_0131)
Cancer chemotherapy within two weeks prior to start of blinatumomab treatment
Item
Cancer chemotherapy within two weeks prior to start of blinatumomab treatment
boolean
C0392920 (UMLS CUI 2011AA)
150415003 (SNOMED CT 2011_0131)
C0205448 (UMLS CUI 2011AA)
19338005 (SNOMED CT 2011_0131)
C0439230 (UMLS CUI 2011AA)
258705008 (SNOMED CT 2011_0131)
WK (HL7 V3 2006_05)
C0332152 (UMLS CUI 2011AA)
288556008 (SNOMED CT 2011_0131)
C3853839 (UMLS CUI 2011AA)
C0039798 (UMLS CUI 2011AA)
Immunotherapy (e.g. rituximab) within four weeks prior to start of blinatumomab treatment
Item
Immunotherapy (e.g. rituximab) within four weeks prior to start of blinatumomab treatment
boolean
C0021083 (UMLS CUI 2011AA)
146638005 (SNOMED CT 2011_0131)
C0732355 (UMLS CUI 2011AA)
386919002 (SNOMED CT 2011_0131)
C0205450 (UMLS CUI 2011AA)
9362000 (SNOMED CT 2011_0131)
C0439230 (UMLS CUI 2011AA)
258705008 (SNOMED CT 2011_0131)
WK (HL7 V3 2006_05)
C0332152 (UMLS CUI 2011AA)
288556008 (SNOMED CT 2011_0131)
C3853839 (UMLS CUI 2011AA)
C0039798 (UMLS CUI 2011AA)
Infection with HIV or hepatitis B (HBsAg positive) or hepatitis C virus (anti-HCV positive)
Item
Infection with HIV or hepatitis B (HBsAg positive) or hepatitis C virus (anti-HCV positive)
boolean
C0019693 (UMLS CUI 2011AA)
86406008 (SNOMED CT 2011_0131)
10020161 (MedDRA 14.1)
MTHU020829 (LOINC Version 232)
B20 (ICD-10-CM Version 2010)
042 (ICD-9-CM Version 2011)
C0019163 (UMLS CUI 2011AA)
66071002 (SNOMED CT 2011_0131)
10019731 (MedDRA 14.1)
C0149709 (UMLS CUI 2011AA)
165806002 (SNOMED CT 2011_0131)
10019742 (MedDRA 14.1)
C0220847 (UMLS CUI 2011AA)
62944002 (SNOMED CT 2011_0131)
10019752 (MedDRA 14.1)
C0281863 (UMLS CUI 2011AA)
10019747 (MedDRA 14.1)
Pregnant or nursing women
Item
Pregnant or nursing women
boolean
C0549206 (UMLS CUI 1)
10036586 (MedDRA 14.1)
C0006147 (UMLS CUI 2)
10006247 (MedDRA 14.1)
224526002 (SNOMED CT 2011_0131)
Previous treatment with blinatumomab
Item
Previous treatment with blinatumomab
boolean
C1514463 (UMLS CUI 2011AA)
C3853839 (UMLS CUI 2011AA)