Age
Item
age ≥18 years.
boolean
C0001779 (UMLS CUI [1])
Liver Cirrhosis Imaging | Liver Cirrhosis Biopsy of liver
Item
cirrhotic liver demonstrated by typical liver dysmorphy on imaging and/or liver biopsy.
boolean
C0023890 (UMLS CUI [1,1])
C0011923 (UMLS CUI [1,2])
C0023890 (UMLS CUI [2,1])
C0193388 (UMLS CUI [2,2])
Liver carcinoma | Lesion Diameter Computed Tomography | Lesion Diameter MRI | Lesion Quantity | Liver carcinoma Biopsy
Item
hcc with at least one lesion measuring more than 1 cm in diameter with a single dynamic imaging technique (ct or mri), showing intense arterial uptake followed by washout of contrast in the venous-delayed phases, or diagnosed by biopsy.
boolean
C2239176 (UMLS CUI [1])
C0221198 (UMLS CUI [2,1])
C1301886 (UMLS CUI [2,2])
C0040405 (UMLS CUI [2,3])
C0221198 (UMLS CUI [3,1])
C1301886 (UMLS CUI [3,2])
C0024485 (UMLS CUI [3,3])
C0221198 (UMLS CUI [4,1])
C1265611 (UMLS CUI [4,2])
C2239176 (UMLS CUI [5,1])
C0005558 (UMLS CUI [5,2])
Borderline Lesion Resectable | Borderline Lesion Eligible Excision | Borderline Lesion Eligible Radiofrequency destruction
Item
borderline resectable disease eligible for surgical resection or radiofrequency destruction.
boolean
C1332594 (UMLS CUI [1,1])
C1514888 (UMLS CUI [1,2])
C1332594 (UMLS CUI [2,1])
C1548635 (UMLS CUI [2,2])
C0728940 (UMLS CUI [2,3])
C1332594 (UMLS CUI [3,1])
C1548635 (UMLS CUI [3,2])
C0441517 (UMLS CUI [3,3])
Absence Dissemination Extrahepatic
Item
no extra-hepatic dissemination.
boolean
C0332197 (UMLS CUI [1,1])
C0205221 (UMLS CUI [1,2])
C1517058 (UMLS CUI [1,3])
ECOG performance status
Item
ecog performance status < 2.
boolean
C1520224 (UMLS CUI [1])
Childbearing Potential Contraceptive methods | Hormonal contraception | Contraception, Barrier | Sexual Abstinence
Item
women of child-bearing potential must agree to use adequate contraception (hormonal or barrier method of birth control, abstinence) prior to study entry and for the duration of study participation. should a woman become pregnant or suspect she is pregnant while participating in this study, she should inform her treating physician immediately.
boolean
C3831118 (UMLS CUI [1,1])
C0700589 (UMLS CUI [1,2])
C2985296 (UMLS CUI [2])
C0004764 (UMLS CUI [3])
C0036899 (UMLS CUI [4])
Informed Consent
Item
signed written informed consent (approved by an independent ethics committee) obtained prior to any study specific baseline procedures.
boolean
C0021430 (UMLS CUI [1])
Decompensated cirrhosis of liver Child-Pugh Classification
Item
decompensated cirrhosis (child pugh b, c).
boolean
C1619727 (UMLS CUI [1,1])
C4050412 (UMLS CUI [1,2])
Tumor Spread Extrahepatic
Item
extra-hepatic tumour spread.
boolean
C0027651 (UMLS CUI [1,1])
C0332261 (UMLS CUI [1,2])
C1517058 (UMLS CUI [1,3])
Cancer Other | Exception Basal cell carcinoma
Item
previous or concomitant malignancies within five years other than basal cell carcinoma of the skin.
boolean
C1707251 (UMLS CUI [1])
C1705847 (UMLS CUI [2,1])
C0007117 (UMLS CUI [2,2])
Pregnancy | Breast Feeding | Contraceptive methods Refused | Hormonal contraception Refused | Barrier Contraception Refused | Sexual Abstinence Refused
Item
pregnancy, lactation or refusal to use adequate contraceptive measures (hormonal or barrier method of birth control, abstinence).
boolean
C0032961 (UMLS CUI [1])
C0006147 (UMLS CUI [2])
C0700589 (UMLS CUI [3,1])
C1705116 (UMLS CUI [3,2])
C2985296 (UMLS CUI [4,1])
C1705116 (UMLS CUI [4,2])
C0004764 (UMLS CUI [5,1])
C1705116 (UMLS CUI [5,2])
C0036899 (UMLS CUI [6,1])
C1705116 (UMLS CUI [6,2])
Liver disease Pre-existing | Liver Abscess | Liver sarcoidosis | Tuberculosis, Hepatic | Cholangitis, Sclerosing
Item
pre-existing other hepatic disease (liver abscess, hepatic sarcoidosis or tuberculosis, sclerosing cholangitis, …).
boolean
C0023895 (UMLS CUI [1,1])
C2347662 (UMLS CUI [1,2])
C0023885 (UMLS CUI [2])
C0744822 (UMLS CUI [3])
C0041313 (UMLS CUI [4])
C0008313 (UMLS CUI [5])
Transarterial Radioembolization
Item
previous trans-arterial radioembolization (tare).
boolean
C3889650 (UMLS CUI [1])
Allergic Reaction Compound Investigational New Drugs Similar
Item
history of allergic reactions attributed to compounds of similar chemical or biologic composition of the administered materials.
boolean
C1527304 (UMLS CUI [1,1])
C1706082 (UMLS CUI [1,2])
C0013230 (UMLS CUI [1,3])
C2348205 (UMLS CUI [1,4])
Bleeding tendency | Ischemia Cardiovascular | Cerebrovascular accident
Item
bleeding diathesis, history of cardiovascular ischemic disease or cerebrovascular incident within the last six months.
boolean
C1458140 (UMLS CUI [1])
C0022116 (UMLS CUI [2,1])
C3887460 (UMLS CUI [2,2])
C0038454 (UMLS CUI [3])
Major surgery
Item
major surgery within four weeks.
boolean
C0679637 (UMLS CUI [1])
Comorbidity Uncontrolled | Communicable Disease | Symptomatic congestive heart failure | Angina, Unstable | Cardiac Arrhythmia | Mental disorders Limiting Protocol Compliance | Social situation Limiting Protocol Compliance
Item
uncontrolled concurrent illness including, but not limited to ongoing or active infection, symptomatic congestive heart failure, unstable angina pectoris, cardiac arrhythmia, or psychiatric illness/social situations that would limit compliance with study requirements.
boolean
C0009488 (UMLS CUI [1,1])
C0205318 (UMLS CUI [1,2])
C0009450 (UMLS CUI [2])
C0742758 (UMLS CUI [3])
C0002965 (UMLS CUI [4])
C0003811 (UMLS CUI [5])
C0004936 (UMLS CUI [6,1])
C0439801 (UMLS CUI [6,2])
C0525058 (UMLS CUI [6,3])
C0748872 (UMLS CUI [7,1])
C0439801 (UMLS CUI [7,2])
C0525058 (UMLS CUI [7,3])
Diabetic - poor control
Item
uncontrolled diabetes.
boolean
C0421258 (UMLS CUI [1])