Age
Item
Is the participant older than 45 years of age?
boolean
C0001779 (UMLS CUI [1])
Pack Years
Item
Has the participant smoked more than 20 pack years?
boolean
C1277691 (UMLS CUI [1])
Concurrent NSAID use
Item
Is the participant concurrently using NSAIDs?
boolean
C4060806 (UMLS CUI [1,1])
C0003211 (UMLS CUI [1,2])
Celecoxib hypersensitivity
Item
Does the participant have hypersensitivity to celecoxib?
boolean
C0020517 (UMLS CUI [1,1])
C0538927 (UMLS CUI [1,2])
Sulfonamide allergy
Item
Does the participant have a documented allergic-type reaction to sulfonamides?
boolean
C1301725 (UMLS CUI [1,1])
C1527304 (UMLS CUI [1,2])
C0038760 (UMLS CUI [1,3])
Hypersensitivity reaction to aspiring or NSAIDs
Item
Does the participant have a history of allergic reaction, urticaria or asthma to aspirin or other NSAIDs?
boolean
C0262926 (UMLS CUI [1,1])
C1527304 (UMLS CUI [1,2])
C0004057 (UMLS CUI [1,3])
C0262926 (UMLS CUI [2,1])
C0042109 (UMLS CUI [2,2])
C0004057 (UMLS CUI [2,3])
C0262926 (UMLS CUI [3,1])
C0004096 (UMLS CUI [3,2])
C0004057 (UMLS CUI [3,3])
C0262926 (UMLS CUI [4,1])
C1527304 (UMLS CUI [4,2])
C0003211 (UMLS CUI [4,3])
C0262926 (UMLS CUI [5,1])
C0042109 (UMLS CUI [5,2])
C0003211 (UMLS CUI [5,3])
C0262926 (UMLS CUI [6,1])
C0004096 (UMLS CUI [6,2])
C0003211 (UMLS CUI [6,3])
Liver dysfunction
Item
Does the participant have a history of liver dysfunction?
boolean
C0262926 (UMLS CUI [1,1])
C0086565 (UMLS CUI [1,2])
Fluid retention problems
Item
Does the participant have hypertension or cardiac conditions aggravated by fluid retention and edema?
boolean
C0020538 (UMLS CUI [1,1])
C0436331 (UMLS CUI [1,2])
C0268000 (UMLS CUI [1,3])
C0013604 (UMLS CUI [1,4])
C0262402 (UMLS CUI [2,1])
C0436331 (UMLS CUI [2,2])
C0268000 (UMLS CUI [2,3])
C0013604 (UMLS CUI [2,4])
Gastrointestinal ulcer complications
Item
Does the participant have a previous history of gastrointestinal ulceration, bleeding, or perforation?
boolean
C0262926 (UMLS CUI [1,1])
C0237938 (UMLS CUI [1,2])
C0262926 (UMLS CUI [2,1])
C0017181 (UMLS CUI [2,2])
C0262926 (UMLS CUI [3,1])
C0151664 (UMLS CUI [3,2])
Renal dysfunction
Item
Does the participant have renal dysfunction?
boolean
C3279454 (UMLS CUI [1])
End-stage Respiratory Disease
Item
Does the participant have end stage respiratory disease?
boolean
C0205088 (UMLS CUI [1,1])
C0035204 (UMLS CUI [1,2])
Unstable Angina
Item
Does the participant have unstable angina?
boolean
C0002965 (UMLS CUI [1])
Other malignancy
Item
Does the participant have any other malignancy?
boolean
C0006826 (UMLS CUI [1,1])
C0205394 (UMLS CUI [1,2])
Pregnancy
Item
Is the participant pregnant?
boolean
C0032961 (UMLS CUI [1])
Cytochrom system interference
Item
Does the participant have a concurrent use of medication known to alter or be affected by alteration of the hepatic p450 2c9 and 2d6 enzymes?
boolean
C4060806 (UMLS CUI [1,1])
C1515926 (UMLS CUI [1,2])
C0608437 (UMLS CUI [1,3])
C0057223 (UMLS CUI [1,4])
Interfering Medical Conditions
Item
Does the patient have concurrent medical conditions that may interfere with completion of tests, therapy, or the follow-up schedule?
boolean
C0205476 (UMLS CUI [1,1])
C0348080 (UMLS CUI [1,2])
C0521102 (UMLS CUI [1,3])
C0205197 (UMLS CUI [1,4])
C0039593 (UMLS CUI [1,5])
C0205476 (UMLS CUI [2,1])
C0348080 (UMLS CUI [2,2])
C0521102 (UMLS CUI [2,3])
C0205197 (UMLS CUI [2,4])
C0087111 (UMLS CUI [2,5])
C0205476 (UMLS CUI [3,1])
C0348080 (UMLS CUI [3,2])
C0521102 (UMLS CUI [3,3])
C0205197 (UMLS CUI [3,4])
C1522577 (UMLS CUI [3,5])