ECG normal | Safety Assessment Normal
Item
normal ecg and safety assessments, or minor no-relevant deviations, at screening
boolean
C0522054 (UMLS CUI [1])
C0549076 (UMLS CUI [2,1])
C0205307 (UMLS CUI [2,2])
Vital signs | Systolic Pressure | Diastolic blood pressure | Heart rate
Item
vital signs: systolic between 100 and 140 mmhg and diastolic between 50 and 90 mmhg and heart rate between 45 and 90 beats/min
boolean
C0518766 (UMLS CUI [1])
C0871470 (UMLS CUI [2])
C0428883 (UMLS CUI [3])
C0018810 (UMLS CUI [4])
Pharmaceutical Preparations Intake Absent
Item
no medication intake in the last four weeks
boolean
C0013227 (UMLS CUI [1,1])
C1512806 (UMLS CUI [1,2])
C0332197 (UMLS CUI [1,3])
Informed Consent | Protocol Compliance
Item
volunteers must have signed an informed consent document indicating that they understand the purpose of and procedures required for the study and are willing to participate in the study and to adhere to the prohibitions and restrictions specified in the protocol
boolean
C0021430 (UMLS CUI [1])
C0525058 (UMLS CUI [2])
Drug screen negative
Item
negative drug screen
boolean
C0919819 (UMLS CUI [1])
Study Subject Participation Status
Item
participation in another clinical trial in the last 3 months
boolean
C2348568 (UMLS CUI [1])
Hypersensitivity | Diathesis allergic | Ketamine allergy | Hypersensitivity Ketamine Ingredient | Hypersensitivity Benzethonium Chloride
Item
significant allergies, allergic diathesis or known hypersensitivity for ketamine or its ingredients (ie, benzethonium chloride)
boolean
C0020517 (UMLS CUI [1])
C0012655 (UMLS CUI [2,1])
C0700624 (UMLS CUI [2,2])
C0570631 (UMLS CUI [3])
C0020517 (UMLS CUI [4,1])
C0022614 (UMLS CUI [4,2])
C1550600 (UMLS CUI [4,3])
C0020517 (UMLS CUI [5,1])
C0079015 (UMLS CUI [5,2])
Respiration Disorder | Cardiovascular Disease | Endocrine System Diseases | Gastrointestinal Disease | Nervous system disorder | Glaucoma | Liver Failure | Kidney Failure
Item
history of or current significant respiratory disease, cardiovascular disease, endocrinological, gastrointestinal, neurological, glaucoma and known liver and kidney failure
boolean
C0035204 (UMLS CUI [1])
C0007222 (UMLS CUI [2])
C0014130 (UMLS CUI [3])
C0017178 (UMLS CUI [4])
C0027765 (UMLS CUI [5])
C0017601 (UMLS CUI [6])
C0085605 (UMLS CUI [7])
C0035078 (UMLS CUI [8])
Medical contraindication MRI | Claustrophobia | Parts Metallic | Artificial cardiac pacemaker
Item
contraindications for an mri being performed (claustrophobia, metal parts, pacemaker)
boolean
C1301624 (UMLS CUI [1,1])
C0024485 (UMLS CUI [1,2])
C0008909 (UMLS CUI [2])
C0449719 (UMLS CUI [3,1])
C2986473 (UMLS CUI [3,2])
C0030163 (UMLS CUI [4])
Oxygen saturation PO2 measurement
Item
oxygen saturation po2 < 90 mmhg
boolean
C0369768 (UMLS CUI [1,1])
C1283004 (UMLS CUI [1,2])
ECG abnormality | Laboratory test result abnormal
Item
clinically significant abnormalities in ecg or laboratory values
boolean
C0522055 (UMLS CUI [1])
C0438215 (UMLS CUI [2])
Substance Use Disorders
Item
recent history (within previous 6 months) of alcohol or drug abuse
boolean
C0038586 (UMLS CUI [1])
Mental disorders | Nervous system disorder
Item
history of or current psychiatric diagnoses (dsm-iv, ii) or neurological disorders
boolean
C0004936 (UMLS CUI [1])
C0027765 (UMLS CUI [2])
Schizophrenia First Degree Relative | Schizophrenia Second Degree Relative
Item
relatives in first or second degree with a schizophrenic disorder
boolean
C0036341 (UMLS CUI [1,1])
C1517194 (UMLS CUI [1,2])
C0036341 (UMLS CUI [2,1])
C1519210 (UMLS CUI [2,2])
Serology positive Hepatitis B Surface Antigens | Serology positive Hepatitis C Antibodies | Serology positive HIV Antibodies
Item
serology positive for hepatitis b surface antigen, hepatitis c antibodies or hiv antibodies
boolean
C0242089 (UMLS CUI [1,1])
C0019168 (UMLS CUI [1,2])
C0242089 (UMLS CUI [2,1])
C0166049 (UMLS CUI [2,2])
C0242089 (UMLS CUI [3,1])
C0019683 (UMLS CUI [3,2])
Signs Hyperthyroidism | Triiodothyronine measurement | Thyroxine measurement | Thyroid stimulating hormone measurement
Item
signs of hyperthyroidism based on the determination of t3, t4 and tsh
boolean
C0311392 (UMLS CUI [1,1])
C0020550 (UMLS CUI [1,2])
C0428419 (UMLS CUI [2])
C0202231 (UMLS CUI [3])
C0202230 (UMLS CUI [4])