Schizophrenia Primary
Item
primary diagnosis of schizophrenia
boolean
C0036341 (UMLS CUI [1,1])
C0205225 (UMLS CUI [1,2])
Age
Item
man or woman, aged between 18 and 55 years
boolean
C0001779 (UMLS CUI [1])
Axis I diagnosis Primary | Exception Schizophrenia
Item
current axis i primary psychiatric diagnosis other than schizophrenia
boolean
C0270287 (UMLS CUI [1,1])
C0205225 (UMLS CUI [1,2])
C1705847 (UMLS CUI [2,1])
C0036341 (UMLS CUI [2,2])
Antipsychotic Agents Absent Schizophrenia
Item
not previously received antipsychotic drugs for schizophrenia
boolean
C0040615 (UMLS CUI [1,1])
C0332197 (UMLS CUI [1,2])
C0036341 (UMLS CUI [1,3])
Exacerbation acute Hospitalization Required
Item
acute exacerbation requiring hospitalisation within the last 3 months
boolean
C0743630 (UMLS CUI [1,1])
C1708385 (UMLS CUI [1,2])
Extrapyramidal sign
Item
clinically significant extrapyramidal symptoms
boolean
C0234133 (UMLS CUI [1])
Cardiovascular Disease | Congestive heart failure | Cardiac Hypertrophy | Cardiac Arrhythmia | Bradycardia
Item
clinically significant cardiovascular disease, congestive heart failure, cardiac hypertrophy, arrhythmia or bradycardia
boolean
C0007222 (UMLS CUI [1])
C0018802 (UMLS CUI [2])
C1383860 (UMLS CUI [3])
C0003811 (UMLS CUI [4])
C0428977 (UMLS CUI [5])
Congenital long QT syndrome | Family history Congenital long QT syndrome | Prolonged QT interval Acquired
Item
congenital long qt syndrome or a family history of this disease, or known acquired qt interval prolongation
boolean
C1141890 (UMLS CUI [1])
C0241889 (UMLS CUI [2,1])
C1141890 (UMLS CUI [2,2])
C0151878 (UMLS CUI [3,1])
C0439661 (UMLS CUI [3,2])
ECG abnormality
Item
significant ecg abnormalities
boolean
C0522055 (UMLS CUI [1])
Hypokalemia | Hypomagnesemia
Item
hypokalaemia or hypomagnesaemia
boolean
C0020621 (UMLS CUI [1])
C0151723 (UMLS CUI [2])
CYP3A Inhibitors
Item
in concurrent treatment with drugs inhibiting the p450 enzymes system cyp3a
boolean
C3850056 (UMLS CUI [1])