Non-Squamous Non-Small Cell Lung Carcinoma
Item
non-squamous cell non small cell lung cancer (nsclc) disease
boolean
C4324656 (UMLS CUI [1])
TNM clinical staging | Recurrent disease Post Operative Surgical Procedures
Item
clinical stage iiib/iv or recurrent disease after surgery
boolean
C3258246 (UMLS CUI [1])
C0277556 (UMLS CUI [2,1])
C0687676 (UMLS CUI [2,2])
C0543467 (UMLS CUI [2,3])
Systemic Chemotherapy Absent | Immunotherapy Absent | Targeted Therapy Absent | Biological treatment Absent | Adjuvant therapy Absent
Item
no prior systemic chemotherapy, immunotherapy, targeted therapy or biological therapy, including adjuvant therapy
boolean
C1883256 (UMLS CUI [1,1])
C0332197 (UMLS CUI [1,2])
C0021083 (UMLS CUI [2,1])
C0332197 (UMLS CUI [2,2])
C2985566 (UMLS CUI [3,1])
C0332197 (UMLS CUI [3,2])
C1531518 (UMLS CUI [4,1])
C0332197 (UMLS CUI [4,2])
C0677850 (UMLS CUI [5,1])
C0332197 (UMLS CUI [5,2])
Prior radiation therapy Bone Marrow Percentage
Item
prior radiation therapy is allowed to less than 25% of the bone marrow
boolean
C0279134 (UMLS CUI [1,1])
C0005953 (UMLS CUI [1,2])
C0439165 (UMLS CUI [1,3])
Measurable Disease
Item
measurable disease as defined by response evaluation criteria in solid tumors (recist)
boolean
C1513041 (UMLS CUI [1])
ECOG performance status
Item
the eastern cooperative oncology group (ecog) performance status 0 or 1
boolean
C1520224 (UMLS CUI [1])
Organ function
Item
adequate organ function
boolean
C0678852 (UMLS CUI [1])
Life Expectancy Estimated
Item
estimated life expectancy of at least 12 weeks
boolean
C0023671 (UMLS CUI [1,1])
C0750572 (UMLS CUI [1,2])
Fluid Space Third Clinical Significance
Item
clinically significant third-space fluid collections
boolean
C0005889 (UMLS CUI [1,1])
C1883067 (UMLS CUI [1,2])
C0205437 (UMLS CUI [1,3])
C2826293 (UMLS CUI [1,4])
CNS disorder | Exception Metastatic malignant neoplasm to brain Treated Stable
Item
central nervous system disease other than stable and treated brain metastasis
boolean
C0007682 (UMLS CUI [1])
C1705847 (UMLS CUI [2,1])
C0220650 (UMLS CUI [2,2])
C1522326 (UMLS CUI [2,3])
C0205360 (UMLS CUI [2,4])
Interval Operative Surgical Procedures Enrollment
Item
more than 3 weeks interval between the surgery and enrollment request date
boolean
C1272706 (UMLS CUI [1,1])
C0543467 (UMLS CUI [1,2])
C1516879 (UMLS CUI [1,3])
Aspirin Unable to discontinue | Non-Steroidal Anti-Inflammatory Agents Unable to discontinue
Item
unable to interrupt aspirin or other nonsteroidal anti-inflammatory drugs (nsaids), for a 5 days period
boolean
C0004057 (UMLS CUI [1,1])
C1548265 (UMLS CUI [1,2])
C0003211 (UMLS CUI [2,1])
C1548265 (UMLS CUI [2,2])
Folic Acid Intake Unable | Vitamin B12 supplementation Unable | Folic Acid Intake Unwilling | Vitamin B12 supplementation Unwilling
Item
unable or unwilling to take folic acid or vitamin b12 supplementation
boolean
C0016410 (UMLS CUI [1,1])
C1512806 (UMLS CUI [1,2])
C1299582 (UMLS CUI [1,3])
C4524262 (UMLS CUI [2,1])
C1299582 (UMLS CUI [2,2])
C0016410 (UMLS CUI [3,1])
C1512806 (UMLS CUI [3,2])
C0558080 (UMLS CUI [3,3])
C4524262 (UMLS CUI [4,1])
C0558080 (UMLS CUI [4,2])
Adrenal Cortex Hormones Intake Unable
Item
unable to take corticosteroids.
boolean
C0001617 (UMLS CUI [1,1])
C1512806 (UMLS CUI [1,2])
C1299582 (UMLS CUI [1,3])
Comorbidity Serious compromises Protocol Compliance
Item
serious concomitant disorder that, in the opinion of the investigator, would compromise the patient's ability to adhere to the protocol
boolean
C0009488 (UMLS CUI [1,1])
C0205404 (UMLS CUI [1,2])
C2945640 (UMLS CUI [1,3])
C0525058 (UMLS CUI [1,4])
Interstitial Pneumonia Chest X-ray | Pulmonary Fibrosis Chest X-ray | Interstitial Pneumonia Chest CT | Pulmonary Fibrosis Chest CT
Item
currently have and historically had interstitial pneumonitis (interstitial pneumonia) or pulmonary fibrosis manifested as opacity on chest x-ray or computed tomography (ct)
boolean
C0206061 (UMLS CUI [1,1])
C0039985 (UMLS CUI [1,2])
C0034069 (UMLS CUI [2,1])
C0039985 (UMLS CUI [2,2])
C0206061 (UMLS CUI [3,1])
C0202823 (UMLS CUI [3,2])
C0034069 (UMLS CUI [4,1])
C0202823 (UMLS CUI [4,2])