Agreement Tumor Biopsy
Item
must agree to have a tumor biopsy at screening
boolean
C0680240 (UMLS CUI [1,1])
C0027651 (UMLS CUI [1,2])
C0005558 (UMLS CUI [1,3])
Non-Squamous Non-Small Cell Lung Carcinoma Advanced | Metastatic Non-Squamous Non-Small Cell Lung Carcinoma | Disease Progression Post Prior Therapy
Item
must have a diagnosis of advanced or metastatic non-squamous non-small cell lung cancer that has progressed after certain prior treatment
boolean
C4324656 (UMLS CUI [1,1])
C0205179 (UMLS CUI [1,2])
C4288755 (UMLS CUI [2])
C0242656 (UMLS CUI [3,1])
C0687676 (UMLS CUI [3,2])
C1514463 (UMLS CUI [3,3])
Patient Available Study duration | Protocol Compliance
Item
must be available for the duration of the study and willing to follow the study procedures
boolean
C0030705 (UMLS CUI [1,1])
C0470187 (UMLS CUI [1,2])
C0489652 (UMLS CUI [1,3])
C0525058 (UMLS CUI [2])
Childbearing Potential Pregnancy test negative
Item
if participant is a woman that is capable of having children, must have a negative pregnancy test within 7 days of taking first dose of study drug
boolean
C3831118 (UMLS CUI [1,1])
C0427780 (UMLS CUI [1,2])
Therapeutic radiology procedure Discontinued
Item
must have discontinued radiation therapy at least 4 weeks before entering this study
boolean
C1522449 (UMLS CUI [1,1])
C1444662 (UMLS CUI [1,2])
Drugs, Non-Prescription
Item
must not have taken an unapproved drug as treatment for any indication within the last 28 days before starting study treatment.
boolean
C0013231 (UMLS CUI [1])
Pregnancy | Breast Feeding | Pregnancy considering | Reproduction considering | Females & males of reproductive potential Contraceptive methods
Item
must not be pregnant or lactating, are considering becoming pregnant, or are considering fathering a child. males and females with reproductive potential must agree to use medically approved contraceptive precautions during the trial until the patient's physician considers it safe to become pregnant or father a child.
boolean
C0032961 (UMLS CUI [1])
C0006147 (UMLS CUI [2])
C0032961 (UMLS CUI [3,1])
C0750591 (UMLS CUI [3,2])
C0035150 (UMLS CUI [4,1])
C0750591 (UMLS CUI [4,2])
C4034483 (UMLS CUI [5,1])
C0700589 (UMLS CUI [5,2])
HIV Seropositivity | Hepatitis B surface antigen positive | Hepatitis C antibody test positive
Item
must not have known positive test in human immunodeficiency virus (hiv), hepatitis b surface antigen (hbsag), or hepatitis c antibodies (hcab).
boolean
C0019699 (UMLS CUI [1])
C0149709 (UMLS CUI [2])
C1277805 (UMLS CUI [3])
Study Subject Participation Status | Involvement with LY2603618
Item
must not have previously participated in a study involving ly2603618
boolean
C2348568 (UMLS CUI [1])
C1314939 (UMLS CUI [2,1])
C2825835 (UMLS CUI [2,2])
Pemetrexed Relationship Cancer treatment
Item
must not have previously taken pemetrexed for cancer
boolean
C0210657 (UMLS CUI [1,1])
C0439849 (UMLS CUI [1,2])
C0920425 (UMLS CUI [1,3])
Hypersensitivity LY2603618 | Hypersensitivity Pemetrexed
Item
must not have a known allergy to ly2603618 or pemetrexed
boolean
C0020517 (UMLS CUI [1,1])
C2825835 (UMLS CUI [1,2])
C0020517 (UMLS CUI [2,1])
C0210657 (UMLS CUI [2,2])
Communicable Disease Affecting Therapeutic aspects
Item
must not currently have an infection that may affect patient's ability to tolerate the therapy
boolean
C0009450 (UMLS CUI [1,1])
C0392760 (UMLS CUI [1,2])
C0039798 (UMLS CUI [1,3])
Medical condition Serious Study Subject Participation Status At risk | Disease Serious Study Subject Participation Status At risk | Diabetic - poor control | Chest Pain Due to Heart Disease
Item
must not have a serious medical condition or disorder that would make it unsafe for you to participate in the study such as uncontrolled diabetes or chest pain due to heart disease
boolean
C3843040 (UMLS CUI [1,1])
C0205404 (UMLS CUI [1,2])
C2348568 (UMLS CUI [1,3])
C1444641 (UMLS CUI [1,4])
C0012634 (UMLS CUI [2,1])
C0205404 (UMLS CUI [2,2])
C2348568 (UMLS CUI [2,3])
C1444641 (UMLS CUI [2,4])
C0421258 (UMLS CUI [3])
C0008031 (UMLS CUI [4,1])
C0678226 (UMLS CUI [4,2])
C0018799 (UMLS CUI [4,3])
Non-Steroidal Anti-Inflammatory Agents Discontinue Able | Ibuprofen Discontinue Able
Item
if taking certain medications called non-steroidal anti-inflammatory drugs (nsaids), such as ibuprofen, must be able to stop taking these medications according to certain guidelines
boolean
C0003211 (UMLS CUI [1,1])
C1444662 (UMLS CUI [1,2])
C0085732 (UMLS CUI [1,3])
C0020740 (UMLS CUI [2,1])
C1444662 (UMLS CUI [2,2])
C0085732 (UMLS CUI [2,3])