Age
Item
male or female, 18 years of age or over.
boolean
C0001779 (UMLS CUI [1])
Therapy naive Essential Hypertension Stage | Antihypertensive therapy Absent | Blood pressure measurement
Item
naïve patients with stage i** or stage ii** (jnc vii) essential hypertension or patients uncontrolled on current hypotensive drug therapy (in cuff bp>140/90mm hg)
boolean
C0919936 (UMLS CUI [1,1])
C0085580 (UMLS CUI [1,2])
C0699749 (UMLS CUI [1,3])
C0585941 (UMLS CUI [2,1])
C0332197 (UMLS CUI [2,2])
C0005824 (UMLS CUI [3])
Informed Consent
Item
all selected patients must give their written informed consent before recording their personal data
boolean
C0021430 (UMLS CUI [1])
Secondary hypertension
Item
subject with secondary form of hypertension
boolean
C0155616 (UMLS CUI [1])
Myocardial Infarction Treated | DECOMPENSATED CONGESTIVE HEART FAILURE Treated | Angina Pectoris Treated | Sick Sinus Syndrome Treated | Second degree atrioventricular block Treated | Complete atrioventricular block Treated | Myocardial Infarction Unstable | DECOMPENSATED CONGESTIVE HEART FAILURE Unstable | Angina, Unstable | Sick Sinus Syndrome Unstable | Second degree atrioventricular block Unstable | Complete atrioventricular block Unstable
Item
subject is being treated or with unstable condition for disease of myocardial infarction, clinically decompensated congestive heart failure, angina pectoris, sick sinus syndrome, second or third degree atrioventricular block
boolean
C0027051 (UMLS CUI [1,1])
C1522326 (UMLS CUI [1,2])
C0742746 (UMLS CUI [2,1])
C1522326 (UMLS CUI [2,2])
C0002962 (UMLS CUI [3,1])
C1522326 (UMLS CUI [3,2])
C0037052 (UMLS CUI [4,1])
C1522326 (UMLS CUI [4,2])
C0264906 (UMLS CUI [5,1])
C1522326 (UMLS CUI [5,2])
C0151517 (UMLS CUI [6,1])
C1522326 (UMLS CUI [6,2])
C0027051 (UMLS CUI [7,1])
C0443343 (UMLS CUI [7,2])
C0742746 (UMLS CUI [8,1])
C0443343 (UMLS CUI [8,2])
C0002965 (UMLS CUI [9])
C0037052 (UMLS CUI [10,1])
C0443343 (UMLS CUI [10,2])
C0264906 (UMLS CUI [11,1])
C0443343 (UMLS CUI [11,2])
C0151517 (UMLS CUI [12,1])
C0443343 (UMLS CUI [12,2])
Hypertensive Encephalopathy | Hypertensive Retinopathy Grade
Item
subject with history of hypertensive encephalopathy, grade 3 or 4 hypertensive retinopathy within 3 months before entering this trial
boolean
C0151620 (UMLS CUI [1])
C0152132 (UMLS CUI [2,1])
C0441800 (UMLS CUI [2,2])
Cerebrovascular accident
Item
subjects with a cerebrovascular accident within 6 months before entering this trial
boolean
C0038454 (UMLS CUI [1])
Autoimmune Disease
Item
subject with auto-immune disease
boolean
C0004364 (UMLS CUI [1])
Endocrine System Diseases Uncontrolled | Hyperthyroidism | Hypothyroidism | Adrenal Gland Hyperfunction | Adrenal gland hypofunction
Item
subject with uncontrolled endocrine diseases, such as hyperthyroidism, hypothyroidism, hypercorticism and hypocorticism
boolean
C0014130 (UMLS CUI [1,1])
C0205318 (UMLS CUI [1,2])
C0020550 (UMLS CUI [2])
C0020676 (UMLS CUI [3])
C0001622 (UMLS CUI [4])
C0001623 (UMLS CUI [5])
Renal Insufficiency | Serum creatinine raised
Item
subject with confirmed evidence of renal impairment (creatinine > 1.5 x upper limit of normal)
boolean
C1565489 (UMLS CUI [1])
C0700225 (UMLS CUI [2])
Hyperkalemia | Serum potassium measurement
Item
subject with hyperkalemia with serum potassium > 5.5 meq/l
boolean
C0020461 (UMLS CUI [1])
C0302353 (UMLS CUI [2])
Malignant disease End-stage
Item
subject with terminal stage of malignant disease
boolean
C0442867 (UMLS CUI [1,1])
C0205088 (UMLS CUI [1,2])
Substance Use Disorders
Item
subject with substance abuse history
boolean
C0038586 (UMLS CUI [1])
Gastrointestinal Disease Interferes with Absorption Oral medication
Item
subject with gastrointestinal disease which can interfere the absorption of the oral medications
boolean
C0017178 (UMLS CUI [1,1])
C0521102 (UMLS CUI [1,2])
C0237442 (UMLS CUI [1,3])
C0175795 (UMLS CUI [1,4])
Medical contraindication Angiotensin II receptor antagonist | Medical contraindication Calcium Channel Blockers
Item
subject with any contraindication to the use of angiotensin ii receptor blocker or calcium channel blocker
boolean
C1301624 (UMLS CUI [1,1])
C0521942 (UMLS CUI [1,2])
C1301624 (UMLS CUI [2,1])
C0006684 (UMLS CUI [2,2])
Pregnancy | Breast Feeding
Item
subject is pregnant or lactating
boolean
C0032961 (UMLS CUI [1])
C0006147 (UMLS CUI [2])
Premenopausal state Contraceptive methods Absent
Item
premenopausal subjects not taking reliable methods for contraceptives
boolean
C0232969 (UMLS CUI [1,1])
C0700589 (UMLS CUI [1,2])
C0332197 (UMLS CUI [1,3])
Disease Serious | Study Subject Participation Status Excluded
Item
subject with any other serious disease considered by the investigator not in the condition to enter the trial
boolean
C0012634 (UMLS CUI [1,1])
C0205404 (UMLS CUI [1,2])
C2348568 (UMLS CUI [2,1])
C0332196 (UMLS CUI [2,2])
Protocol Compliance Unable
Item
subject is not able to comply to the protocol requirements
boolean
C0525058 (UMLS CUI [1,1])
C1299582 (UMLS CUI [1,2])
Study Subject Participation Status | Investigational New Drugs
Item
subject participated investigational drug trial within 3 months before entering this study
boolean
C2348568 (UMLS CUI [1])
C0013230 (UMLS CUI [2])