Diabetes Mellitus, Non-Insulin-Dependent
Item
have type 2 diabetes mellitus.
boolean
C0011860 (UMLS CUI [1])
Body mass index
Item
have a body mass index within range 22 to 35kg/m2 inclusive.
boolean
C1305855 (UMLS CUI [1])
Female Sterilization | Postmenopausal state
Item
females who meet above criteria must be physiologically incapable of becoming pregnant (i.e., surgically sterilized, or post-menopausal per protocol definition).
boolean
C0015787 (UMLS CUI [1])
C0232970 (UMLS CUI [2])
Insulin regime
Item
are currently taking insulin therapy.
boolean
C0557978 (UMLS CUI [1])
Heart Diseases | Liver diseases | Hematological Disease | nervous system disorder | Kidney Diseases | Malignant Neoplasms
Item
have any disease (such as heart, liver, blood, nervous system, or kidney disease, or cancer).
boolean
C0018799 (UMLS CUI [1])
C0023895 (UMLS CUI [2])
C0018939 (UMLS CUI [3])
C0027765 (UMLS CUI [4])
C0022658 (UMLS CUI [5])
C0006826 (UMLS CUI [6])
Stomach Disease Interferes with Investigational New Drugs | Liver disease Interferes with Investigational New Drugs | Kidney Disease Interferes with Investigational New Drugs | Disease Interferes with Investigational New Drugs
Item
have a history of stomach, liver, kidney, or other disease that with interfere with taking the study drug.
boolean
C0038354 (UMLS CUI [1,1])
C0521102 (UMLS CUI [1,2])
C0013230 (UMLS CUI [1,3])
C0023895 (UMLS CUI [2,1])
C0521102 (UMLS CUI [2,2])
C0013230 (UMLS CUI [2,3])
C0022658 (UMLS CUI [3,1])
C0521102 (UMLS CUI [3,2])
C0013230 (UMLS CUI [3,3])
C0012634 (UMLS CUI [4,1])
C0521102 (UMLS CUI [4,2])
C0013230 (UMLS CUI [4,3])
Diuretics | Adrenal Cortex Hormones Oral | corticosteroids injection
Item
are currently using diuretics, oral or injectable corticosteroids (inhaled &
boolean
C0012798 (UMLS CUI [1])
C0001617 (UMLS CUI [2,1])
C1527415 (UMLS CUI [2,2])
C2095490 (UMLS CUI [3])
Inhaled steroids Excluded | Adrenal Cortex Hormones Intranasal Excluded | Pharmaceutical Preparations Causing Depletion Fluid Balance | Regimen Stable Heart condition | Pharmaceutical Preparations Interfere with Investigational New Drugs
Item
intranasal corticosteroids are permitted), or other medications that would cause you to deplete your fluid balance in your body; currently taking stable regimens for heart conditions; currently using prescription or non-prescription drugs within 7 days of starting the study that may interfere with the study drug.
boolean
C2065041 (UMLS CUI [1,1])
C2828389 (UMLS CUI [1,2])
C0001617 (UMLS CUI [2,1])
C1522019 (UMLS CUI [2,2])
C2828389 (UMLS CUI [2,3])
C0013227 (UMLS CUI [3,1])
C0678227 (UMLS CUI [3,2])
C0333668 (UMLS CUI [3,3])
C0016284 (UMLS CUI [3,4])
C0040808 (UMLS CUI [4,1])
C0205360 (UMLS CUI [4,2])
C3842523 (UMLS CUI [4,3])
C0013227 (UMLS CUI [5,1])
C0521102 (UMLS CUI [5,2])
C0013230 (UMLS CUI [5,3])
Blood Donation Blood Amount
Item
would donate more than 450 ml of blood over a 2 month period.
boolean
C0005794 (UMLS CUI [1,1])
C0005767 (UMLS CUI [1,2])
C1265611 (UMLS CUI [1,3])
Study Subject Participation Status Unfavorable | Urinary tract infection | Infective cystitis | Drinking Beer Quantity Daily | Drinking Wine Quantity Daily | Drinking Spirit Quantity Daily
Item
physician does not think it is a good idea for you to participate in the trial.- had a urinary tract infection or bladder infection in the last month. - are currently drinking more than 2 beers, 1 glass of wine, or 1 glass of spirits daily.
boolean
C2348568 (UMLS CUI [1,1])
C3640815 (UMLS CUI [1,2])
C0042029 (UMLS CUI [2])
C0600041 (UMLS CUI [3])
C0001948 (UMLS CUI [4,1])
C0004922 (UMLS CUI [4,2])
C1265611 (UMLS CUI [4,3])
C0332173 (UMLS CUI [4,4])
C0001948 (UMLS CUI [5,1])
C0043188 (UMLS CUI [5,2])
C1265611 (UMLS CUI [5,3])
C0332173 (UMLS CUI [5,4])
C0001948 (UMLS CUI [6,1])
C0301611 (UMLS CUI [6,2])
C1265611 (UMLS CUI [6,3])
C0332173 (UMLS CUI [6,4])
Urine drug screen positive
Item
have a positive urine drug screen test.
boolean
C0743300 (UMLS CUI [1])
Tobacco use Habits Change Planned
Item
plan to change your smoking habits during the course of the trial.
boolean
C0543414 (UMLS CUI [1,1])
C2242848 (UMLS CUI [1,2])
C0392747 (UMLS CUI [1,3])
C1301732 (UMLS CUI [1,4])
Hepatitis C | Hepatitis B | HIV Infection
Item
have hepatitis c, hepatitis b, or hiv. -
boolean
C0019196 (UMLS CUI [1])
C0019163 (UMLS CUI [2])
C0019693 (UMLS CUI [3])
Laboratory test result abnormal | ECG abnormality | Hypertensive disease | Hypotension
Item
have a lab or ekg abnormality. - high or low blood pressure.
boolean
C0438215 (UMLS CUI [1])
C0522055 (UMLS CUI [2])
C0020538 (UMLS CUI [3])
C0020649 (UMLS CUI [4])
Investigational New Drugs | Investigational Medical Device
Item
have used of any investigational drug or device during the study or within 30 days prior to 1st dosing of study medication.
boolean
C0013230 (UMLS CUI [1])
C2346570 (UMLS CUI [2])
Gender Sexual Abstinence Unwilling | Gender Contraceptive methods Unwilling
Item
are a male subject unwilling to abstain or use protection during intercourse.
boolean
C0079399 (UMLS CUI [1,1])
C0036899 (UMLS CUI [1,2])
C0558080 (UMLS CUI [1,3])
C0079399 (UMLS CUI [2,1])
C0700589 (UMLS CUI [2,2])
C0558080 (UMLS CUI [2,3])