Chronic Lymphocytic Leukemia
Item
diagnosis of cll as defined by the nci-working group
boolean
C0023434 (UMLS CUI [1])
Systemic Chemotherapy Standard | Immunotherapy
Item
previous treatment with standard systemic chemotherapy or immunotherapy.
boolean
C1883256 (UMLS CUI [1,1])
C1442989 (UMLS CUI [1,2])
C0021083 (UMLS CUI [2])
Progressive Disease | Recurrent disease Post Therapeutic procedure
Item
disease progression or relapse after treatment.
boolean
C1335499 (UMLS CUI [1])
C0277556 (UMLS CUI [2,1])
C0687676 (UMLS CUI [2,2])
C0087111 (UMLS CUI [2,3])
Indication Therapeutic procedure
Item
indication for treatment as defined by the nci working group guidelines (cheson, 1996)
boolean
C3146298 (UMLS CUI [1,1])
C0087111 (UMLS CUI [1,2])
ECOG performance status
Item
ecog performance status ≤ 2
boolean
C1520224 (UMLS CUI [1])
Liver function | Renal function | Bone Marrow function
Item
adequate liver and renal and bone marrow function
boolean
C0232741 (UMLS CUI [1])
C0232804 (UMLS CUI [2])
C0005953 (UMLS CUI [3,1])
C0031843 (UMLS CUI [3,2])
Chemotherapy Chronic Lymphocytic Leukemia | Monoclonal Antibody Therapy Chronic Lymphocytic Leukemia | Therapeutic radiology procedure Chronic Lymphocytic Leukemia | Toxic effect resolved CTCAE Grades
Item
treatment of cll with chemotherapy, monoclonal antibody or radiotherapy within 60 days prior to entering the study. acute toxicities from prior therapy must have resolved to grade ≤ 1.
boolean
C0392920 (UMLS CUI [1,1])
C0023434 (UMLS CUI [1,2])
C0279694 (UMLS CUI [2,1])
C0023434 (UMLS CUI [2,2])
C1522449 (UMLS CUI [3,1])
C0023434 (UMLS CUI [3,2])
C0600688 (UMLS CUI [4,1])
C1514893 (UMLS CUI [4,2])
C1516728 (UMLS CUI [4,3])
Heart Disease New York Heart Association Classification
Item
class 3 or 4 cardiac disease as defined by the new york heart association functional classification
boolean
C0018799 (UMLS CUI [1,1])
C1275491 (UMLS CUI [1,2])
Lung disease Severe | Lung disease Debilitation | Dyspnea at rest | Shortness of breath Significant | Chronic Obstructive Airway Disease
Item
severe or debilitating pulmonary disease (dyspnea at rest, significant shortness of breath, copd)
boolean
C0024115 (UMLS CUI [1,1])
C0205082 (UMLS CUI [1,2])
C0024115 (UMLS CUI [2,1])
C0742985 (UMLS CUI [2,2])
C0743330 (UMLS CUI [3])
C0013404 (UMLS CUI [4,1])
C0750502 (UMLS CUI [4,2])
C0024117 (UMLS CUI [5])
Secondary Malignant Neoplasm | Malignant Neoplasms
Item
active secondary malignancy or history of other malignancy within the last five years
boolean
C3266877 (UMLS CUI [1])
C0006826 (UMLS CUI [2])
Mycoses Symptomatic | Bacterial Infection Symptomatic | Virus Disease Symptomatic | HIV Infection | Hepatitis A | Hepatitis B | Hepatitis C
Item
active symptomatic fungal, bacterial and/or viral infection including active hiv or viral hepatitis (a, b or c).
boolean
C0026946 (UMLS CUI [1,1])
C0231220 (UMLS CUI [1,2])
C0004623 (UMLS CUI [2,1])
C0231220 (UMLS CUI [2,2])
C0042769 (UMLS CUI [3,1])
C0231220 (UMLS CUI [3,2])
C0019693 (UMLS CUI [4])
C0019159 (UMLS CUI [5])
C0019163 (UMLS CUI [6])
C0019196 (UMLS CUI [7])
Medical contraindication rituximab
Item
patients who are contraindicated for treatment with rituximab
boolean
C1301624 (UMLS CUI [1,1])
C0393022 (UMLS CUI [1,2])
Prolymphocytic Leukemia | Hairy Cell Leukemia | Leukemic Phase of Non-Hodgkin's Lymphoma | Chronic Lymphocytic Leukemia | Malignant Neoplasm B-Lymphocytes
Item
diagnosis of prolymphocytic leukemia, hairy cell leukemia, leukemic phase of non-hodgkin's lymphoma, or other non-b-cll b-cell malignancy;
boolean
C0023486 (UMLS CUI [1])
C0023443 (UMLS CUI [2])
C0852709 (UMLS CUI [3])
C0023434 (UMLS CUI [4])
C0006826 (UMLS CUI [5,1])
C0004561 (UMLS CUI [5,2])
Leukemia, T-Cell, Chronic | Malignant Neoplasm T-Lymphocyte
Item
t-cll or other t-cell malignancy
boolean
C0023494 (UMLS CUI [1])
C0006826 (UMLS CUI [2,1])
C0039194 (UMLS CUI [2,2])