postmenopausal female
Item
postmenopausal female, 55-75 years old
boolean
C0232970 (UMLS CUI [1,1])
C0086287 (UMLS CUI [1,2])
type 2 diabetes, american diabetes association
Item
history of type ii diabetes, as defined by the american diabetes association for more than 5 years that is either insulin requiring or treated with oral therapies such as sulfonylureas and metformin
boolean
C0011860 (UMLS CUI [1,1])
C1705019 (UMLS CUI [1,2])
bmi
Item
body mass index (bmi) of 19-35
boolean
C1305855 (UMLS CUI [1])
able to move
Item
able to move without walkers and without a history of long periods (>3 months) of inactivity
boolean
C0578670 (UMLS CUI [1])
fractures
Item
additional inclusion criteria for fracture participants: fractures of the proximal humerus and femur as well as the ankle and foot should have occurred after the onset of diabetes and should have been caused by a low energy trauma such as falling from standing height. all fractures will be verified by radiographs.
boolean
C0016658 (UMLS CUI [1])
neuropathic disease
Item
severe neuropathic disease such as neurogenic osteoarthropathies (i.e., charcot joints) of the foot
boolean
C0003892 (UMLS CUI [1])
steroid use, comorbidity affecting osteoporosis development
Item
steroid users or have disease conditions that could play a significant role in the development of osteoporosis such as idiopathic osteoporosis, immobilization, hyperparathyroidism, or hyperthyroidism
boolean
C0281991 (UMLS CUI [1])
C0029456 (UMLS CUI [2,1])
C1527148 (UMLS CUI [2,2])
C0009488 (UMLS CUI [2,3])
bone metabolism disorder
Item
diseases that may affect bone metabolism: alcoholism, chronic drug use, chronic gastrointestinal disease, renal or hepatic impairment
boolean
C0005944 (UMLS CUI [1])
antacids, estrogen, steroids, anticonvulsants, anticoagulants, vitamin a
Item
chronic treatment with antacids, estrogen, adrenal or anabolic steroids, anticonvulsants, anticoagulants, or pharmacologic doses of vitamin a supplements 6 months prior
boolean
C0003138 (UMLS CUI [1])
C0279494 (UMLS CUI [2])
C0038317 (UMLS CUI [3])
C0003286 (UMLS CUI [4])
C0003280 (UMLS CUI [5])
C0042839 (UMLS CUI [6])
rosiglitazone, pioglitazone
Item
diabetic patients on rosiglitazone or pioglitazone medications
boolean
C0289313 (UMLS CUI [1])
C0071097 (UMLS CUI [2])
high energy trauma
Item
high energy trauma, e.g., due to motor vehicle accidents
boolean
C3263723 (UMLS CUI [1])
pathologic fractures
Item
pathological fractures of other origin, i.e., tumor, tumor-like lesions as well as focal demineralization visualized on radiographs
boolean
C0016663 (UMLS CUI [1])
fluoride, bisphosphonate, calcitonin, tamoxifen
Item
history of fluoride, bisphosphonate, calcitonin or tamoxifen use
boolean
C0016327 (UMLS CUI [1])
C0012544 (UMLS CUI [2])
C0006668 (UMLS CUI [3])
C0039286 (UMLS CUI [4])
cardiovascular disease, uncontrolled hypertension
Item
history of unstable cardiovascular disease or uncontrolled hypertension
boolean
C0007222 (UMLS CUI [1])
C1868885 (UMLS CUI [2])
mri contraindication
Item
mri contraindications
boolean
C0024485 (UMLS CUI [1,1])
C0522473 (UMLS CUI [1,2])
bmi
Item
body mass index greater than 35
boolean
C1305855 (UMLS CUI [1])