diagnosis of breast cancer
Item
histological or cytological confirmation of breast cancer that is either
boolean
C0019638 (UMLS CUI [1])
patient with primary tumor
Item
a primary tumor in a patient unfit for or who has declined surgery
boolean
C0677930 (UMLS CUI [1,1])
C0677930 (UMLS CUI [1,2])
C0749192 (UMLS CUI [2])
advanced disease
Item
advanced (locally or metastatic) disease
boolean
C0679246 (UMLS CUI [1])
resistance to tamoxifen or ER negative tumour
Item
acquired resistance to tamoxifen or er negative tumour
boolean
C0332325 (UMLS CUI [1,1])
C0039286 (UMLS CUI [1,2])
C2584629 (UMLS CUI [2])
measurable disease
Item
at least one measurable or assessable lesion
boolean
C1513041 (UMLS CUI [1])
who performance status
Item
who performance status 0 - 2
boolean
C1520224 (UMLS CUI [1])
life expectancy
Item
life expectancy of 12 weeks or more
boolean
C0023671 (UMLS CUI [1])
previous chemotherapy regimens
Item
more than one previous chemotherapy regimens for advanced disease
boolean
C0205156 (UMLS CUI [1,1])
C0392920 (UMLS CUI [1,2])
prior anthracycline chemotherapy
Item
prior anthracycline chemotherapy (> 250 mg/m2 adriamycin)
boolean
C0003234 (UMLS CUI [1])
radiotherapy completed
Item
radiotherapy completed within 14 days prior to day 1 of treatment
boolean
C1522449 (UMLS CUI [1])
incomplete healing from prior surgery
Item
incomplete healing from prior oncologic or other major surgery
boolean
C0543478 (UMLS CUI [1])
neurological symptoms with spinal cord compression
Item
signs of neurological symptoms consistent with spinal cord compression
boolean
C0235031 (UMLS CUI [1,1])
C0037926 (UMLS CUI [1,2])
active interstitial lung disease
Item
any evidence of clinically active interstitial lung disease (patients with chronic stable
boolean
C0206062 (UMLS CUI [1])