aml de novo
Item
patients with newly diagnosed aml (except acute promyelocytic leukemia) according to the who classification including patients with secondary aml and aml after preceding hematologic disorders
boolean
C0023467 (UMLS CUI [1,1])
C1515568 (UMLS CUI [1,2])
Age
Item
age 18 years or older
boolean
C0001779 (UMLS CUI [1])
informed consent
Item
informed consent. before any study specific procedure including randomisation is done or before study medication is administered, the subject, or legally acceptable representative, must have given written informed consent for participation in the study.
boolean
C0021430 (UMLS CUI [1])
APL
Item
acute promyelocytic leukemia (apl)
boolean
C0023487 (UMLS CUI [1])
previous or concurrent malignancies
Item
previous or concurrent malignancies other than aml
boolean
C2735088 (UMLS CUI [1])
C0006826 (UMLS CUI [2,1])
C0205420 (UMLS CUI [2,2])
colony stimulating factor, interleukins or interferons
Item
previous treatment with colony-stimulating factors, interleukins or interferons
boolean
C0009392 (UMLS CUI [1])
C0021764 (UMLS CUI [2])
C0021747 (UMLS CUI [3])
hypersensitivity to escherichia coli derived products
Item
known hypersensitivity to escherichia coli derived products (e.g. filgrastim, humulin® insulin, l-asparaginase, humatrope® growth hormone, intron a®)
boolean
C0020517 (UMLS CUI [1,1])
C0014834 (UMLS CUI [1,2])
immunotherapy
Item
antibody-based or cell-based immunotherapies
boolean
C0021083 (UMLS CUI [1])
respiratory insufficiency
Item
respiratory insufficiency with po2 <60 mmhg
boolean
C0035229 (UMLS CUI [1])
C0202155 (UMLS CUI [2])
heart failure
Item
heart failure nyha iii° or iv°
boolean
C1275491 (UMLS CUI [1])
creatinine
Item
elevated creatinine >2.0 mg/dl
boolean
C0201976 (UMLS CUI [1])
bilirubin
Item
elevated bilirubin >2.0 mg/dl
boolean
C1278039 (UMLS CUI [1])
pregnancy or lactation
Item
pregnancy or lactation
boolean
C0032961 (UMLS CUI [1,1])
C0006147 (UMLS CUI [1,2])
contraception females
Item
females without adequate contraception
boolean
C0700589 (UMLS CUI [1])
C0086287 (UMLS CUI [2])
hiv and/or hepatitis c
Item
known hiv and/or hepatitis c infection
boolean
C0019682 (UMLS CUI [1,1])
C0019196 (UMLS CUI [1,2])
severe neurologic or psychiatric disease
Item
severe neurologic or psychiatric disease
boolean
C0009488 (UMLS CUI [1])
disorder limiting informed consent
Item
psychiatric, addictive, or any disorder, which compromises ability to give truly informed consent for participation in this study
boolean
C0021430 (UMLS CUI [1,1])
C0439801 (UMLS CUI [1,2])
C0009488 (UMLS CUI [1,3])
compliance behavior
Item
concerns for subject's compliance with the protocol procedures
boolean
C1321605 (UMLS CUI [1])
compliance behaviour
Item
lack of willingness to record and circulate personal disease-related informations defined in the study protocol
boolean
C1321605 (UMLS CUI [1])