Gender | Core needle biopsy | Abnormality of the breast Suspicious Breast Carcinoma | Breast Carcinoma Core needle biopsy
Item
women undergoing core needle biopsy for a breast abnormality suspicious for breast cancer. women who have undergone a core needle biopsy demonstrating breast cancer who have not yet had any further therapy are also eligible so long as their core needle biopsy is available for analysis.
boolean
C0079399 (UMLS CUI [1])
C1318309 (UMLS CUI [2])
C4025829 (UMLS CUI [3,1])
C0750493 (UMLS CUI [3,2])
C0678222 (UMLS CUI [3,3])
C0678222 (UMLS CUI [4,1])
C1318309 (UMLS CUI [4,2])
Prior Therapy Absent Breast Carcinoma
Item
no prior therapy for breast cancer.
boolean
C1514463 (UMLS CUI [1,1])
C0332197 (UMLS CUI [1,2])
C0678222 (UMLS CUI [1,3])
Age
Item
age 18 years or older.
boolean
C0001779 (UMLS CUI [1])
Comprehension Informed Consent | Informed Consent Willing
Item
ability to understand and the willingness to sign a written informed consent document.
boolean
C0162340 (UMLS CUI [1,1])
C0021430 (UMLS CUI [1,2])
C0021430 (UMLS CUI [2,1])
C0600109 (UMLS CUI [2,2])
Informed Consent
Item
signed informed consent
boolean
C0021430 (UMLS CUI [1])
Parathyroid Diseases | Hypercalcemia | Kidney Calculi
Item
history of parathyroid disease, hypercalcemia, or kidney stones.
boolean
C0030517 (UMLS CUI [1])
C0020437 (UMLS CUI [2])
C0022650 (UMLS CUI [3])
Vitamin D supplement | Exception Standard Multivitamin preparation | Exception Standard Calcium + vitamin D | Exception Calcium Citrate / Vitamin D
Item
supplemental vitamin d other than from a standard multiple vitamin or from standard formulations of calcium and vitamin d (e.g. calcium citrate with vitamin d) within the prior 6 months.
boolean
C3541352 (UMLS CUI [1])
C1705847 (UMLS CUI [2,1])
C1442989 (UMLS CUI [2,2])
C0301532 (UMLS CUI [2,3])
C1705847 (UMLS CUI [3,1])
C1442989 (UMLS CUI [3,2])
C0719107 (UMLS CUI [3,3])
C1705847 (UMLS CUI [4,1])
C0719098 (UMLS CUI [4,2])
Kidney Failure Requirement Dialysis | Kidney Failure Requirement Kidney Transplantation
Item
history of renal failure requiring dialysis or kidney transplantation.
boolean
C0035078 (UMLS CUI [1,1])
C1514873 (UMLS CUI [1,2])
C0011946 (UMLS CUI [1,3])
C0035078 (UMLS CUI [2,1])
C1514873 (UMLS CUI [2,2])
C0022671 (UMLS CUI [2,3])
Pregnancy | Breast Feeding
Item
women who are known to be pregnant or who are nursing. (as vitamin d does not have toxicity to the fetus, a negative pregnancy test is not a requirement to participate in the study.)
boolean
C0032961 (UMLS CUI [1])
C0006147 (UMLS CUI [2])
Calcium supplement U/day
Item
supplemental calcium greater than 600 mg calcium per day during study.
boolean
C3540037 (UMLS CUI [1,1])
C0456683 (UMLS CUI [1,2])
First line treatment Breast Carcinoma | Breast-Conserving Surgery Absent | Mastectomy Absent
Item
patients for who initial treatment of their breast cancer will not be with breast conserving surgery or mastectomy.
boolean
C1708063 (UMLS CUI [1,1])
C0678222 (UMLS CUI [1,2])
C0917927 (UMLS CUI [2,1])
C0332197 (UMLS CUI [2,2])
C0024881 (UMLS CUI [3,1])
C0332197 (UMLS CUI [3,2])
Locally advanced breast cancer
Item
patients with locally advanced breast cancer
boolean
C3495949 (UMLS CUI [1])
Chemotherapy Neoadjuvant Planned | Hormone Therapy Planned | Systemic therapy Planned
Item
patients planned for neoadjuvant chemotherapy, hormonal therapy, or other systemic therapy.
boolean
C0392920 (UMLS CUI [1,1])
C0600558 (UMLS CUI [1,2])
C1301732 (UMLS CUI [1,3])
C0279025 (UMLS CUI [2,1])
C1301732 (UMLS CUI [2,2])
C1515119 (UMLS CUI [3,1])
C1301732 (UMLS CUI [3,2])
Therapeutic radiology procedure Preoperative Planned
Item
patients planned for preoperative radiation therapy.
boolean
C1522449 (UMLS CUI [1,1])
C0445204 (UMLS CUI [1,2])
C1301732 (UMLS CUI [1,3])
Operative Surgical Procedure Planned Breast Carcinoma | Vitamin D Intervention Illicit
Item
patients with planned surgical therapy of their breast cancer that would not allow for at least 10 days of vitamin d intervention.
boolean
C0543467 (UMLS CUI [1,1])
C1301732 (UMLS CUI [1,2])
C0678222 (UMLS CUI [1,3])
C0042866 (UMLS CUI [2,1])
C0184661 (UMLS CUI [2,2])
C0332266 (UMLS CUI [2,3])
Condition Interferes with Investigational New Drugs
Item
any condition potentially interfering with subjects ability to comply with taking study medication.
boolean
C0348080 (UMLS CUI [1,1])
C0521102 (UMLS CUI [1,2])
C0013230 (UMLS CUI [1,3])
Medical condition Interferes with Vitamin D Absorption | Celiac Disease | Ulcerative Colitis
Item
any medical condition that would potentially interfere with vitamin d absorption, such as celiac sprue, ulcerative colitis.
boolean
C3843040 (UMLS CUI [1,1])
C0521102 (UMLS CUI [1,2])
C0042866 (UMLS CUI [1,3])
C0237442 (UMLS CUI [1,4])
C0007570 (UMLS CUI [2])
C0009324 (UMLS CUI [3])
Risk Increased by Study Subject Participation Status
Item
current participation in another research study that would increase risk to subject, in the opinion of the investigators
boolean
C0035647 (UMLS CUI [1,1])
C0205217 (UMLS CUI [1,2])
C2348568 (UMLS CUI [1,3])