mean pulmonary arterial pressure; right heart catheterization
Item
a mean pulmonary arterial pressure of 25 mmhg measured by right heart catheterization.
boolean
C3854605 (UMLS CUI [1])
C0189896 (UMLS CUI [2])
pulmonary hypertension Association Chronic Obstructive Airway Disease
Item
a diagnosis of copd-associated pulmonary hypertension, implicating that no other potential cause of pulmonary hypertension is present.
boolean
C0020542 (UMLS CUI [1,1])
C1511978 (UMLS CUI [1,2])
C0024117 (UMLS CUI [1,3])
copd; Adrenergic beta-Antagonists; exacerbation
Item
stable copd, defined by no subjective alterations of symptoms or use of short acting beta-antagonists for minimally six weeks. any exacerbation resulting in admission to hospital or other contacts to a physician must have ceased for at least 6 weeks before entering the study.
boolean
C0024117 (UMLS CUI [1])
C0001645 (UMLS CUI [2])
C0235874 (UMLS CUI [3])
age
Item
age > 18
boolean
C0001779 (UMLS CUI [1])
informed consent
Item
informed written consent.
boolean
C0021430 (UMLS CUI [1])
Contraception status
Item
reliable anticonception for fertile women.
boolean
C0420837 (UMLS CUI [1])
rheumatic disease; Ability to walk limited
Item
rheumatic disease limiting walking capacity.
boolean
C0035435 (UMLS CUI [1])
C0559964 (UMLS CUI [2,1])
C0439801 (UMLS CUI [2,2])
exacerbation copd
Item
exacerbation in copd during the study.
boolean
C0235874 (UMLS CUI [1,1])
C0024117 (UMLS CUI [1,2])
age
Item
age>80 years
boolean
C0001779 (UMLS CUI [1])
fev1
Item
fev1 < 25 % of predicted.
boolean
C3815113 (UMLS CUI [1])
hypersensitivity sildenafil
Item
allergy towards contents of sildenafil or placebo tablets.
boolean
C0020517 (UMLS CUI [1,1])
C0529793 (UMLS CUI [1,2])
blood pressure
Item
fall in blood pressure of > 30 mmhg systolic or >20 mmhg diastolic after intake of the first dose of trial medication.
boolean
C0005823 (UMLS CUI [1])
medication dose; peripheral saturation
Item
fall in peripheral saturation of > 5% after intake of the first dose of trial medication.
boolean
C3174092 (UMLS CUI [1])
C2317096 (UMLS CUI [2])
treatment nitrous vasodilators
Item
treatment with nitrous vasodilators or aminophyllamines.
boolean
C0087111 (UMLS CUI [1,1])
C0360716 (UMLS CUI [1,2])