hepatocellular carcinoma
Item
1. histologically proven hepatocellular carcinoma.
boolean
C2239176 (UMLS CUI [1])
surgery
Item
2. hcc underwent curative resection within 6 weeks before registration.
boolean
C0543467 (UMLS CUI [1])
resection margin
Item
3. grossly, the resection margin should be > 1 cm.
boolean
C0229985 (UMLS CUI [1])
Age
Item
4. patients must be younger than 70 year-old.
boolean
C0001779 (UMLS CUI [1])
ecog
Item
5. patients must have a performance status of ecog score < 2.
boolean
C1520224 (UMLS CUI [1])
liver function and hemogram
Item
6. patients must have adequate liver reservation and adequate hemogram.
boolean
C0232741 (UMLS CUI [1])
C0200631 (UMLS CUI [2])
pugh-child score
Item
7. pugh-child‘s score < 7.
boolean
C4050412 (UMLS CUI [1])
bilirubin
Item
8. the serum total bilirubin level are < 2 mg/dl.
boolean
C1278039 (UMLS CUI [1])
prothrombin time
Item
9. the prothrombin times are < 3 sec above normal control.
boolean
C0033707 (UMLS CUI [1])
platelets
Item
10. the platelet are > 10 x 104 / mm3.
boolean
C0005821 (UMLS CUI [1])
wbc
Item
11. the wbc are > 3,000 / mm3.
boolean
C0023508 (UMLS CUI [1])
creatinine
Item
12. patient must have serum creatinine < 1.5 mg/dl
boolean
C0201976 (UMLS CUI [1])
nyha
Item
13. cardiac function with nyha classification < grade ii
boolean
C1275491 (UMLS CUI [1])
hbv or hcv
Item
14. known hbv or hcv status.
boolean
C0019163 (UMLS CUI [1])
C0019196 (UMLS CUI [2])
informed consent
Item
15. signed informed consent.
boolean
C0021430 (UMLS CUI [1])
ID.16
Item
exclusion criteria:
boolean
surgery
Item
1. patients who have non-curative resection are not eligible.
boolean
C0543467 (UMLS CUI [1])
resection margins
Item
2. resected hccs with histologically positive margins are not eligible.
boolean
C0229985 (UMLS CUI [1])
portal vein thrombus
Item
3. hccs with radiological evidence of portal vein thrombus are not eligible.
boolean
C2239176 (UMLS CUI [1])
C0087086 (UMLS CUI [2,1])
C0032718 (UMLS CUI [2,2])
steroids or immunosuppressant agents
Item
4. patients with other systemic diseases which required concurrent usage of glucocorticosteroid or immunosuppressant agent(s) are not eligible.
boolean
C0038317 (UMLS CUI [1])
C0021081 (UMLS CUI [2])
malignancies
Item
5. patients with advanced second primary malignancy are not eligible.
boolean
C0006826 (UMLS CUI [1])
pregnant or breast-feeding
Item
6. patients with pregnacy or breast-feeding are not eligible.
boolean
C0032961 (UMLS CUI [1])
C0006147 (UMLS CUI [2])
cardiopulmonary disease
Item
7. patients with severe cardiopulmonary diseases are not eligible.
boolean
C0009488 (UMLS CUI [1])
psychiatric disorder
Item
8. patients with clinically significant psychiatric disorder are not eligible.
boolean
C0004936 (UMLS CUI [1])
chemotherapy, immuno-therapeutic drugs or steroids within 6 weeks
Item
9. patients who had antineoplastic chemotherapeutic or immuno-therapeutic drugs or corticosteroids within 6 weeks of commencing the protocol are not eligible.
boolean
C3665472 (UMLS CUI [1])
C0876248 (UMLS CUI [2])
C0007222 (UMLS CUI [3])