hormone refractory prostate cancer
Item
patients with hormone refractory prostate cancer, refractory multiple myeloma, refractory bladder cancer, or malignant lymphoma;
boolean
C1328504 (UMLS CUI [1])
C0278620 (UMLS CUI [2])
C0024299 (UMLS CUI [3])
life expectancy
Item
life expectancy of ≥6 months,
boolean
C0023671 (UMLS CUI [1])
zubrod performance status
Item
zubrod performance status of ≤2,
boolean
C3714786 (UMLS CUI [1])
adequate bone marrow function
Item
adequate bone marrow function, renal function, liver function and pulmonary function;
boolean
C0005953 (UMLS CUI [1])
C0232804 (UMLS CUI [2])
C0232741 (UMLS CUI [3])
C0231921 (UMLS CUI [4])
age
Item
age ≥ 18 years;
boolean
C0001779 (UMLS CUI [1])
informed consent
Item
willing and able to give informed consent; and
boolean
C0021430 (UMLS CUI [1])
contraceptive use
Item
effective contraceptive use or non child-bearing potential.
boolean
C1999124 (UMLS CUI [1])
Weight loss
Item
10% weight loss in the previous 3 months;
boolean
C1262477 (UMLS CUI [1])
active serious infection
Item
active serious infection not controlled by antibiotics;
boolean
C0009450 (UMLS CUI [1])
bisphosphonates
Item
initiation of bisphosphonates treatment within 30 days;
boolean
C0012544 (UMLS CUI [1])
participation in other research
Item
participation in other research study within 30 days;
boolean
C2348568 (UMLS CUI [1])
brain metastasis
Item
uncontrolled brain metastasis,
boolean
C0220650 (UMLS CUI [1])
intrathecal chemotherapy or whole-brain radiotherapy
Item
prior intrathecal chemotherapy or whole-brain radiotherapy,
boolean
C1517560 (UMLS CUI [1])
C1520143 (UMLS CUI [2])
compliance behavior
Item
inability to comply with protocol or undergo specified tests;
boolean
C1321605 (UMLS CUI [1])
other malignancy
Item
other active malignancy;
boolean
C0006826 (UMLS CUI [1])
optic neuritis
Item
optic neuritis, and
boolean
C0029134 (UMLS CUI [1])
diuretics
Item
routine use of diuretics (for initial phase of study only).
boolean
C0012798 (UMLS CUI [1])