Breast Carcinoma
Item
histologically confirmed breast cancer
boolean
C0678222 (UMLS CUI [1])
Neoplasm Metastasis | Secondary Neoplasm Localization Diagnostic radiologic examination | Radiography | CT scan | MRI Scan | Ultrasonography | Scintigraphy
Item
metastatic disease, defined by the existence of a secondary tumor localization radiologically (i.e., by radiography, ct scan, mri scan, or ultrasound) or scintigraphically confrimed
boolean
C0027627 (UMLS CUI [1])
C2939419 (UMLS CUI [2,1])
C0475264 (UMLS CUI [2,2])
C0043299 (UMLS CUI [2,3])
C0034571 (UMLS CUI [3])
C0040405 (UMLS CUI [4])
C0917711 (UMLS CUI [5])
C0041618 (UMLS CUI [6])
C0034606 (UMLS CUI [7])
Evaluable Disease
Item
evaluable disease
boolean
C1516986 (UMLS CUI [1])
First line treatment Neoplasm Metastasis | trastuzumab | Herceptin | Chemotherapy
Item
beginning first-line metastatic treatment with trastuzumab (herceptin®) with or without chemotherapy
boolean
C1708063 (UMLS CUI [1,1])
C0027627 (UMLS CUI [1,2])
C0728747 (UMLS CUI [2])
C0338204 (UMLS CUI [3])
C0392920 (UMLS CUI [4])
primary tumor | ERBB2 Protein Overexpression Immunohistochemistry | Fluorescent in Situ Hybridization
Item
primary tumor must overexpress her2 (ihc 3+ or ihc 2+ and fish+ or fish+)
boolean
C0677930 (UMLS CUI [1])
C1515560 (UMLS CUI [2,1])
C0021044 (UMLS CUI [2,2])
C0162789 (UMLS CUI [3])
Hormone Receptor Status Unspecified
Item
hormone receptor status not specified
boolean
C0019929 (UMLS CUI [1,1])
C0449438 (UMLS CUI [1,2])
C0205370 (UMLS CUI [1,3])
Metastatic malignant neoplasm to brain
Item
no brain metastasis
boolean
C0220650 (UMLS CUI [1])
Client Characteristics
Item
patient characteristics:
boolean
C0815172 (UMLS CUI [1])
Menopausal Status Unspecified
Item
menopausal status not specified
boolean
C3829127 (UMLS CUI [1,1])
C0205370 (UMLS CUI [1,2])
Life Expectancy
Item
life expectancy > 3 months
boolean
C0023671 (UMLS CUI [1])
Cardiotoxicity Evaluation Frequency | Left ventricular ejection fraction Isotopic | Ultrasonography
Item
able to undergo cardiotoxicity evaluation every 4 months by measuring lvef via an isotopic method or ultrasound with systematic registration
boolean
C0876994 (UMLS CUI [1,1])
C1261322 (UMLS CUI [1,2])
C0376249 (UMLS CUI [1,3])
C0428772 (UMLS CUI [2,1])
C4038403 (UMLS CUI [2,2])
C0041618 (UMLS CUI [3])
Chronic disease Uncontrolled
Item
no chronic uncontrolled disease
boolean
C0008679 (UMLS CUI [1,1])
C0205318 (UMLS CUI [1,2])
Heart failure
Item
no heart failure
boolean
C0018801 (UMLS CUI [1])
Respiratory Failure | Hypoxemia
Item
no respiratory failure or hypoxemia
boolean
C1145670 (UMLS CUI [1])
C0700292 (UMLS CUI [2])
Primary malignant neoplasm | Basal cell carcinoma
Item
no history of another primary cancer except for basal cell carcinoma of the skin
boolean
C1306459 (UMLS CUI [1])
C0007117 (UMLS CUI [2])
Communicable Disease Uncontrolled Severe
Item
no severe uncontrolled infection
boolean
C0009450 (UMLS CUI [1,1])
C0205318 (UMLS CUI [1,2])
C0205082 (UMLS CUI [1,3])
Mental impairment
Item
no psychological incapacity
boolean
C0683322 (UMLS CUI [1])
Therapeutic procedure
Item
prior concurrent therapy:
boolean
C0087111 (UMLS CUI [1])
disease characteristic
Item
see disease characteristics
boolean
C0599878 (UMLS CUI [1])