Exclusion Criteria
Type 1 Diabetes mellitus
boolean
History of drug or alcohol abuse within the last five years prior to screening
boolean
History of severe or multiple allergies
boolean
Progressive fatal disease
boolean
History of significant cardiovascular, respiratory, gastrointestinal, hepatic (ALAT and/or ASAT > 3 times the normal reference range), neurological, psychiatric and/or haematological disease as judged by the investigator
boolean
Renal insufficiency or history of significant renal diseases (creatinine clearance < 60 ml/min determined using the Cockroft-Goult equation).
boolean
Contra-indications for study drugs including contraindications for the rescue drugs
boolean
Anamnestic history of hypersensitivity to the study drugs or to drugs with similar chemical structures
boolean
Pregnancy or breast feeding
boolean
Sexually active women of childbearing potential not consistently and correctly practicing birth control by implants, injectables, combined oral contraceptives, hormonal intrauterine devices (IUDs), sexual abstinence or vasectomised partner
boolean
Treatment with any other investigational drug within 3 months prior to screening
boolean
Lack of compliance or other similar reason, that according to investigator, precludes satisfactory participation in the study
boolean