Acute alcoholic hepatitis proven by a liver biopsy | Histological findings : neutrophils infiltration, ballooned hepatocytes and mallory bodies
Item
acute alcoholic hepatitis proven by a liver biopsy (necessary histological findings : neutrophils infiltration, ballooned hepatocytes and mallory bodies)
boolean
C0019187 (UMLS CUI [1,1])
C0193388 (UMLS CUI [1,2])
C0001314 (UMLS CUI [1,3])
C0333744 (UMLS CUI [2,1])
C0027950 (UMLS CUI [2,2])
C0332448 (UMLS CUI [2,3])
C0333445 (UMLS CUI [2,4])
C0227525 (UMLS CUI [2,5])
C0449575 (UMLS CUI [2,6])
Discriminat analysis (Total bilirubin measurement, Prothrombin time assay)
Item
presence of a severe disease, defined by a maddrey score higher than or equal to 32, at screening and in baseline (day 0). maddrey score = total bilirubin in mg/dl + 4,6 x (prothrombin time patient in sec - prothrombin time control in sec)
boolean
C0012630 (UMLS CUI [1,1])
C0201913 (UMLS CUI [1,2])
C0033707 (UMLS CUI [1,3])
Age
Item
age between 18 and 75 years old, extremes included
boolean
C0001779 (UMLS CUI [1])
Recent jaundice | Recent aggravation
Item
recent jaundice or in recent aggravation (less than 3 months)
boolean
C0022346 (UMLS CUI [1,1])
C0332185 (UMLS CUI [1,2])
C0541889 (UMLS CUI [2,1])
C0332185 (UMLS CUI [2,2])
Chronic alcohol consumption, quantity
Item
chronic alcohol consumption (more than 40 g/day)
boolean
C0001948 (UMLS CUI [1,1])
C0205191 (UMLS CUI [1,2])
C1265611 (UMLS CUI [1,3])
Informed consent | In case of significant encephalopathy can be an informed consent signed by a family representative
Item
informed consent read, understand and signed by the patient (in case of significant encephalopathy, a family representative can signed in place of the patient)
boolean
C0021430 (UMLS CUI [1])
C0019151 (UMLS CUI [2,1])
C0750502 (UMLS CUI [2,2])
C0021430 (UMLS CUI [2,3])
C0030701 (UMLS CUI [2,4])
Maximal delay between admission and randomization
Item
maximal delay between admission and randomization of 14 days.
boolean
C0184666 (UMLS CUI [1,1])
C0034656 (UMLS CUI [1,2])
C1948053 (UMLS CUI [1,3])
Other disease compromising survival of the patient
Item
other disease compromising 6 months survival of the patient
boolean
C0012634 (UMLS CUI [1,1])
C0205394 (UMLS CUI [1,2])
C2945640 (UMLS CUI [1,3])
C0023671 (UMLS CUI [1,4])
HIV seropositivity | HCV seropositivity | HBs antigen positive
Item
positive hiv or hcv serology, positive hbs antigen
boolean
C0019699 (UMLS CUI [1])
C0850489 (UMLS CUI [2,1])
C1446409 (UMLS CUI [2,2])
C0019168 (UMLS CUI [3,1])
C1446409 (UMLS CUI [3,2])
Uncontrolled bacterial infection | Uncontrolled mycosis
Item
uncontrolled bacterial or fungal infection (infection must be judged controlled for at least 3 days)
boolean
C0004623 (UMLS CUI [1,1])
C0205318 (UMLS CUI [1,2])
C0026946 (UMLS CUI [2,1])
C0205318 (UMLS CUI [2,2])
Uncontrolled upper GI bleeding
Item
uncontrolled upper gi bleeding (bleeding must be controlled for at least 5 days)
boolean
C0041909 (UMLS CUI [1,1])
C0205318 (UMLS CUI [1,2])
Type 1 Hepatorenal syndrome, creatinine measurement
Item
type 1 hepatorenal syndrome (creatinin upper than 2,5 mg/dl), as defined by salerno f et al, gut 2007;56:1310-1318
boolean
C0019212 (UMLS CUI [1,1])
C0201976 (UMLS CUI [1,2])
C0332307 (UMLS CUI [1,3])
History of bariatric surgery
Item
history of bariatric surgery
boolean
C1456587 (UMLS CUI [1,1])
C0262926 (UMLS CUI [1,2])
Pentoxifylline therapy
Item
pentoxyphilline therapy
boolean
C0030899 (UMLS CUI [1])
Molecular Adsorbent Recirculating System
Item
mars therapy
boolean
C0567416 (UMLS CUI [1,1])
C0087111 (UMLS CUI [1,2])