Dietary treatment, sulfonylureas, metformin or insulin
Item
subjects with diabetes mellitus will be eligible if they are receiving dietary treatment for hyperglycemia, sulfonylureas, metformin or insulin
boolean
C1258068 (UMLS CUI [1])
C3653359 (UMLS CUI [2])
C0025598 (UMLS CUI [3])
C0021641 (UMLS CUI [4])
Hba1c
Item
any diabetic subject with a hgba1c level of <7% or >11%
boolean
C0019018 (UMLS CUI [1])
Atherosclerosis
Item
evidence of atherosclerosis
boolean
C0004153 (UMLS CUI [1])
Angina
Item
symptoms of angina
boolean
C0002962 (UMLS CUI [1])
Claudication
Item
symptoms of claudication
boolean
C1456822 (UMLS CUI [1])
Cerebrovascular ischemia
Item
symptoms of cerebrovascular ischemia
boolean
C0917798 (UMLS CUI [1])
Arterial occlusive disease
Item
findings of arterial occlusive disease, as would be suggested by decreased pulses, asymmetric blood pressure, bruits or reduced limb pressure measurements
boolean
C0003838 (UMLS CUI [1])
Systolic and diastolic blood pressure
Item
hypertension defined as a systolic blood pressure > = 150 mmhg and a diastolic blood pressure >= 95 mmhg; (allowable blood pressure medications for diabetic subjects include calcium channel blockers, alpha and beta adrenergic blockers, and diuretics)
boolean
C0871470 (UMLS CUI [1])
C0428883 (UMLS CUI [2])
Total cholesterol andldl cholesterol
Item
hypercholesterolemia, defined as total cholesterol levels greater than 75th percentile for age and sex and ldl cholesterol levels >130mg/dl.
boolean
C1445957 (UMLS CUI [1])
C0202117 (UMLS CUI [2])
Serum creatinine
Item
renal insufficiency (serum creatinine >1.5 mg/dl for men; >1.2 mg/dl for women)
boolean
C0201976 (UMLS CUI [1])
Measurement of liver enzyme
Item
hepatic dysfunction defined as liver enzyme abnormalities > two times the upper limit of normal
boolean
C0428321 (UMLS CUI [1])
Chronic pulmonary disease
Item
chronic pulmonary disease
boolean
C0746102 (UMLS CUI [1])
Congestive heart failure
Item
congestive heart failure
boolean
C0018802 (UMLS CUI [1])
Pregnancy
Item
pregnancy (or subjects planning to become pregnant);
boolean
C0032961 (UMLS CUI [1])
Smoking history
Item
history of cigarette smoking within the last five years;
boolean
C0543414 (UMLS CUI [1])
MI, stroke or unstable angina
Item
history of clinically significant coronary artery or cerebrovascular disease (defined as mi or stroke within 6 months, or presence of unstable angina)
boolean
C0027051 (UMLS CUI [1])
C0038454 (UMLS CUI [2])
C0002965 (UMLS CUI [3])
Vasoactive, cardioactive, or non-steroidal anti-inflammatory medications
Item
use of any, vasoactive, cardioactive, or non-steroidal anti-inflammatory medications within 24 hours of vascular testing visits
boolean
C0042397 (UMLS CUI [1])
C0007220 (UMLS CUI [2])
C0003211 (UMLS CUI [3])