Patient evaluation
Item
evaluation by the surgery and/or liver transplant team has been performed and the patient is not considered a candidate for either "standard" therapy to target area (upper abdomen)
boolean
C0679830 (UMLS CUI [1])
adequate liver function
Item
adequate liver function defined as:
boolean
C0232741 (UMLS CUI [1])
bilrubin, albumin
Item
total bilirubin < 3mg/dl, albumin > 2.5 g/dl
boolean
C0428441 (UMLS CUI [1])
C0728877 (UMLS CUI [2])
normal pt/ptt
Item
normal pt/ptt unless on anticoagulants
boolean
C0030605 (UMLS CUI [1])
mild elevation of liver enzymes
Item
mild elevation of liver enzymes acceptable (must be less than three times upper limit of normal)
boolean
C0235996 (UMLS CUI [1])
renal function
Item
adequate renal function (creatinine < 1.8 mg/dl or creatinine clearance ≥ 50 ml/min)
boolean
C0232804 (UMLS CUI [1])
C0600061 (UMLS CUI [2])
C0812399 (UMLS CUI [3])
bone marrow reserve
Item
adequate bone marrow reserve:
boolean
C0221130 (UMLS CUI [1])
anc count
Item
anc count ≥ 1500 mm3
boolean
C0948762 (UMLS CUI [1])
platelets
Item
platelets ≥ 50,000/mm3
boolean
C0005821 (UMLS CUI [1])
hemoglobin
Item
hemoglobin > 9 g/dl
boolean
C0019046 (UMLS CUI [1])
time of lab values
Item
note: lab values must be obtained within 2 weeks prior to being registered for protocol therapy.
boolean
C0022885 (UMLS CUI [1])
systemic lupus erythematous, rheumatoid arthritis, systemic sclerosis or scleroderma
Item
no history of systemic lupus erythematous, rheumatoid arthritis, systemic sclerosis or scleroderma
boolean
C0024141 (UMLS CUI [1])
C0003873 (UMLS CUI [2])
C0036421 (UMLS CUI [3])
chemotherapy before radiotherapy
Item
no chemotherapy within 14 days before radiotherapy (chemotherapy may cause transient hepatitis with hepatomegaly)
boolean
C0600558 (UMLS CUI [1,1])
C3665472 (UMLS CUI [1,2])
subsequent chemotherapy
Item
no subsequent chemotherapy planned within 2 weeks of radiotherapy
boolean
C3846090 (UMLS CUI [1,1])
C3665472 (UMLS CUI [1,2])
no active liver infection
Item
no active liver infection
boolean
C1112211 (UMLS CUI [1,1])
C2707252 (UMLS CUI [1,2])
no acute hepatitis
Item
no acute hepatitis. definition of active disease:
boolean
C0744827 (UMLS CUI [1])
hepatitis a
Item
hepatitis a: acute hepatitis determined by presence of anti-hav-
boolean
C0019159 (UMLS CUI [1,1])
C0062524 (UMLS CUI [1,2])
hepatitis b
Item
hepatitis b:
boolean
C0019163 (UMLS CUI [1])
hbsag (hb surface antigen
Item
1. hbsag (hb surface antigen): present in patients with acute and chronic hepatitis
boolean
C0019168 (UMLS CUI [1])
hbv dna
Item
2. hbv dna present in patients with active viral replication in amounts greater than 100,000 copies
boolean
C3641250 (UMLS CUI [1,1])
C0042774 (UMLS CUI [1,2])
hbeag
Item
3. hbeag is present in wild type hbv infection and suggests active replication
boolean
C0019167 (UMLS CUI [1,1])
C0042774 (UMLS CUI [1,2])
anti-hbs antibodies
Item
4. anti-hbs: antibody against hbsag appears after hbv infections and confers immunity
boolean
C0201478 (UMLS CUI [1])
anti-hbc-igm
Item
5. anti-hbc-igm: antibody against hbcag, fraction igm, present in acute infection and often could be detected during periods of high viral replication in chronic disease
boolean
C4049590 (UMLS CUI [1,1])
C0042774 (UMLS CUI [1,2])
anti-hbc-igg
Item
6. anti-hbc-igg: is present in chronic disease
boolean
C0312633 (UMLS CUI [1])
C0008679 (UMLS CUI [2])