Age
Item
Is the participant above 18 years of age?
boolean
C0001779 (UMLS CUI [1])
Oropharyngeal squamous cell carcinoma stage
Item
Does the participant have t0-3, n0 to n2c, m0 squamous cell carcinoma of the oropharynx?
boolean
C0280313 (UMLS CUI [1,1])
C1515169 (UMLS CUI [1,2])
C0445081 (UMLS CUI [2])
C0475371 (UMLS CUI [3])
C0475373 (UMLS CUI [4])
C0475374 (UMLS CUI [5])
C0445034 (UMLS CUI [6])
HPV/p16 positive squamous cell carcinoma
Item
Does the participant have. biopsy proven squamous cell carcinoma that is HPV and/or p16 positive?
boolean
C0280313 (UMLS CUI [1,1])
C0005558 (UMLS CUI [1,2])
C4288937 (UMLS CUI [1,3])
C0280313 (UMLS CUI [2,1])
C0005558 (UMLS CUI [2,2])
C4289892 (UMLS CUI [2,3])
Smoking history
Item
Does the participant have ≤ 10 pack-years smoking history or > 5 years of abstinence from smoking?
boolean
C4721824 (UMLS CUI [1,1])
C1277691 (UMLS CUI [1,2])
C0814442 (UMLS CUI [2])
History/physical examination
Item
Did the participant have history/physical examination within 8 weeks prior to registration?
boolean
C0262926 (UMLS CUI [1,1])
C0332152 (UMLS CUI [1,2])
C2985881 (UMLS CUI [1,3])
C0031809 (UMLS CUI [2,1])
C0332152 (UMLS CUI [2,2])
C2985881 (UMLS CUI [2,3])
No metastasis seen
Item
Does the participant have radiologic confirmation of the absence of hematogenous metastasis within 12 weeks prior to registration?
boolean
C0043299 (UMLS CUI [1,1])
C0332197 (UMLS CUI [1,2])
C1512376 (UMLS CUI [1,3])
C0027627 (UMLS CUI [1,4])
C0332152 (UMLS CUI [1,5])
C2985881 (UMLS CUI [1,6])
ECOG
Item
Does the participant have an ecog performance status 0-1?
boolean
C1520224 (UMLS CUI [1])
Adequate bone marrow function
Item
Does the participant have a CBC/Differential obtained within 4 weeks prior to registration, with adequate bone marrow function defined as follows: absolute neutrophil count (anc) ≥ 1,800 cells/mm3; platelets ≥ 100,000 cells/mm3; hemoglobin ≥ 8.0 g/dl?
boolean
C0009555 (UMLS CUI [1,1])
C0205411 (UMLS CUI [1,2])
C0005953 (UMLS CUI [1,3])
C0542341 (UMLS CUI [1,4])
C0545131 (UMLS CUI [2,1])
C0205411 (UMLS CUI [2,2])
C0005953 (UMLS CUI [2,3])
C0542341 (UMLS CUI [2,4])
C0948762 (UMLS CUI [3])
C0032181 (UMLS CUI [4])
C0518015 (UMLS CUI [5])
Adequate Renal and Hepatic function
Item
Does the participant have adequate renal and hepatic function within 4 weeks prior to registration, defined as follows: serum creatinine < 2.0 mg/dl; total bilirubin < 2 x the institutional uln; ast or alt < 3 x the institutional uln?
boolean
C0205411 (UMLS CUI [1,1])
C0232741 (UMLS CUI [1,2])
C0205411 (UMLS CUI [2,1])
C0232804 (UMLS CUI [2,2])
C0201976 (UMLS CUI [3])
C0201913 (UMLS CUI [4])
C0004002 (UMLS CUI [5])
C0001899 (UMLS CUI [6])
Negative serum pregnancy test
Item
Does the participant have a negative serum pregnancy test within 2 weeks prior to registration for women of childbearing potential?
boolean
C0430061 (UMLS CUI [1,1])
C3831118 (UMLS CUI [1,2])
Adequate contraception
Item
Does the participant practice adequate contraception during treatment and for 6 weeks following treatment, if they are a women of childbearing potential or male participants who are sexually active?
boolean
C0205411 (UMLS CUI [1,1])
C0700589 (UMLS CUI [1,2])
C0332282 (UMLS CUI [1,3])
C0087111 (UMLS CUI [1,4])
C4324275 (UMLS CUI [1,5])
C0205411 (UMLS CUI [2,1])
C0700589 (UMLS CUI [2,2])
C0332282 (UMLS CUI [2,3])
C0087111 (UMLS CUI [2,4])
C0241028 (UMLS CUI [2,5])
C0025266 (UMLS CUI [2,6])
Able to comply
Item
Is the participant deemed able to comply with the treatment plan and follow-up schedule?
boolean
C0582784 (UMLS CUI [1])
C0085732 (UMLS CUI [2,1])
C0725694 (UMLS CUI [2,2])
C1522577 (UMLS CUI [2,3])
Informed Consent
Item
Does the participant provide study specific informed consent prior to study entry?
boolean
C0021430 (UMLS CUI [1])
History of head/neck radiation
Item
Does the participant have a prior history of radiation therapy to the head and neck?
boolean
C1522449 (UMLS CUI [1,1])
C0018670 (UMLS CUI [1,2])
C0027530 (UMLS CUI [1,3])
Head/Neck cancer
Item
Does the participant have a prior history of head and neck cancer?
boolean
C0278996 (UMLS CUI [1])
Severe active comorbidity
Item
Does the participant have a severe, active co-morbidity, defined as follows: unstable angina and/or congestive heart failure requiring hospitalization within the last 6 months; transmural myocardial infarction within the last 6 months; acute bacterial or fungal infection requiring intravenous antibiotics at the time of registration; chronic obstructive pulmonary disease exacerbation or other respiratory illness requiring hospitalization or precluding study therapy at the time of registration; hepatic insufficiency resulting in clinical jaundice and/or coagulation defects; note, however, coagulation parameters are not required for entry into this protocol; pre-existing ≥ grade 2 neuropathy; prior organ transplant?
boolean
C0205082 (UMLS CUI [1,1])
C0205177 (UMLS CUI [1,2])
C0009488 (UMLS CUI [1,3])
C1704788 (UMLS CUI [1,4])
C0002965 (UMLS CUI [2,1])
C0019993 (UMLS CUI [2,2])
C0018802 (UMLS CUI [3,1])
C0019993 (UMLS CUI [3,2])
C1400513 (UMLS CUI [4])
C0004623 (UMLS CUI [5,1])
C0013125 (UMLS CUI [5,2])
C0003232 (UMLS CUI [5,3])
C0026946 (UMLS CUI [6,1])
C0013125 (UMLS CUI [6,2])
C0003235 (UMLS CUI [6,3])
C0740304 (UMLS CUI [7,1])
C0019993 (UMLS CUI [7,2])
C1306571 (UMLS CUI [8])
C0442874 (UMLS CUI [9])
C0524930 (UMLS CUI [10])
HIV positive
Item
Is the participant known HIV positive?
boolean
C0019699 (UMLS CUI [1])
Significant hearing loss
Item
Does the participant have significant pre-existing hearing loss, as defined by the patient or treating physician?
boolean
C2347662 (UMLS CUI [1,1])
C3887873 (UMLS CUI [1,2])
C0030705 (UMLS CUI [1,3])
C0011900 (UMLS CUI [1,4])
C2347662 (UMLS CUI [2,1])
C3887873 (UMLS CUI [2,2])
C0030705 (UMLS CUI [2,3])
C0031831 (UMLS CUI [2,4])