informed consent
Item
able to understand and willing to sign the informed consent form
boolean
C0021430 (UMLS CUI [1])
age
Item
<=65 and >=18years old
boolean
C0001779 (UMLS CUI [1])
Pulmonary arterial hypertension; Pulmonary artery mean pressure; Pulmonary Capillary Wedge Pressure | Idiopathic pulmonary hypertension | Familial pulmonary arterial hypertension | Pulmonary arterial hypertension associated with connective tissue disease | Pulmonary arterial hypertension associated with congenital systemic-to-pulmonary shunt; Surgical repair and revision of shunt | Chronic pulmonary thromboembolism; Surgery not indicated
Item
diagnosis of pulmonary arterial hypertension (mean pulmonary artery pressure greater than 25 mm hg at rest with a pulmonary capillary wedge pressure less than 15 mm hg )that is a) idiopathic, b) familial, or c) associated with connective-tissue disease, d)congenital systemic-to-pulmonary shunt occurring after surgical/interventional repair that had been performed at least five years previously or in the absence of indications for surgery/intervention treatment e) chronic thromboembolism pah in the absence of indications for surgery
boolean
C2973725 (UMLS CUI [1])
C0428645 (UMLS CUI [2,1])
C0086879 (UMLS CUI [2,2])
C0152171 (UMLS CUI [3])
C1701939 (UMLS CUI [4])
C3697982 (UMLS CUI [5])
C3698160 (UMLS CUI [6,1])
C0185036 (UMLS CUI [6,2])
C3873396 (UMLS CUI [7,1])
C0420604 (UMLS CUI [7,2])
patients in who functional class ii to iii
Item
patients in who functional class ii to iii
boolean
C4087442 (UMLS CUI [1])
C4087443 (UMLS CUI [2])
vasodilator testing nonresponders
Item
vasodilator testing nonresponders
boolean
C0042402 (UMLS CUI [1,1])
C0919875 (UMLS CUI [1,2])
six-minute walking distance
Item
baseline six-minute walking distance between 100 and 460 m
boolean
C0430515 (UMLS CUI [1])
pah related to other etiologies
Item
pah related to other etiologies (groups 2, 3 and 5 pulmonary hypertension)
boolean
C2973725 (UMLS CUI [1,1])
C1314792 (UMLS CUI [1,2])
forced expiratory volume in one second (FEV1)% (FEV1/FVC) | Forced vital capacity - finding | Total Lung Capacity
Item
a forced expiratory volume in one second/ forced vital capacity below 50% or a total lung capacity of less than 60 percent predicted value
boolean
C3815113 (UMLS CUI [1])
C1287681 (UMLS CUI [2])
C0040509 (UMLS CUI [3])
6 minute walk test
Item
a 6-minute walk distance of less than 100 or more than 460 m
boolean
C0430515 (UMLS CUI [1])
acute vasodilator response
Item
a positive acute vasodilator response
boolean
C0042402 (UMLS CUI [1,1])
C0919876 (UMLS CUI [1,2])
Calcium Channel Blockers | Endothelin receptor antagonist | Phosphodiesterase 5 inhibitor | Prostacycline [EPC]
Item
current treatment with calcium-channel blockers or specific therapy (endothelin receptor antagonist, phosphodiesterase-5 inhibitor, or prostacyclin)
boolean
C0006684 (UMLS CUI [1])
C1134681 (UMLS CUI [2])
C1318700 (UMLS CUI [3])
C2825061 (UMLS CUI [4])
inability to perform 6-minute walk test
Item
inability to perform 6-minute walk test
boolean
C0430515 (UMLS CUI [1,1])
C0085732 (UMLS CUI [1,2])
serum transaminase level
Item
serum transaminase level three times above the upper limit of normal
boolean
C0850712 (UMLS CUI [1])
creatine kinase
Item
creatine kinase level five times above the upper limit of normal
boolean
C0201973 (UMLS CUI [1])
heart disease such as serious cardiac arrhythmias, unstable angina pectoris, myocardial infarction
Item
previously diagnosed heart disease such as serious cardiac arrhythmias, unstable angina pectoris, myocardial infarction
boolean
C0018799 (UMLS CUI [1])
C0003811 (UMLS CUI [2])
C0002965 (UMLS CUI [3])
C0027051 (UMLS CUI [4])
Transient Ischemic Attack | Cerebrovascular accident | Medical History
Item
history of transient ischemia attack or stroke within three months
boolean
C0007787 (UMLS CUI [1])
C0038454 (UMLS CUI [2])
C0262926 (UMLS CUI [3])
bleeding disorder
Item
bleeding disorder
boolean
C0005779 (UMLS CUI [1])
pregnancy, breast feeding
Item
positive pregnancy test or breastfeeding practice
boolean
C0032961 (UMLS CUI [1])
C0006147 (UMLS CUI [2])
limited compliance
Item
history or suspicion of inability to cooperate
boolean
C1321605 (UMLS CUI [1,1])
C0439801 (UMLS CUI [1,2])