evidence of chronic hcv (all genotypes) documented pretransplantation
Item
subjects with evidence of chronic hcv (all genotypes) documented pretransplantation
boolean
Hepatitis C virus RNA assay
Item
hcv rna ≥ 10,000 iu/ml at screening
boolean
C1272251 (UMLS CUI [1])
Absence of organ rejection as documented by recent post transplant liver biopsy
Item
absence of organ rejection as documented by post transplant liver biopsy taken no more than 12 months prior to baseline/day 1 visit
boolean
C0018129 (UMLS CUI [1,1])
C0332197 (UMLS CUI [1,2])
C1301725 (UMLS CUI [1,3])
C0193388 (UMLS CUI [1,4])
C0332185 (UMLS CUI [1,5])
Liver transplant recipient
Item
liver transplant ≥ 6 months and ≤ 12 years prior to screening
boolean
C3811922 (UMLS CUI [1])
No prior therapy with nucleotide/nucleoside treatments for chronic hcv infection
Item
naive to all nucleotide/nucleoside treatments for chronic hcv infection
boolean
C1514463 (UMLS CUI [1,1])
C1579410 (UMLS CUI [1,2])
C0597107 (UMLS CUI [1,3])
C0524910 (UMLS CUI [1,4])
C0332197 (UMLS CUI [1,5])
Multiorgan transplant | Heart transplant recipient | Lung transplant recipient
Item
multiorgan transplant that includes heart or lung recipient
boolean
C2029943 (UMLS CUI [1])
C2063401 (UMLS CUI [2])
De novohepatocellular carcinoma | Recurrent hepatocellular carcinoma(hcc) post transplant
Item
subjects with de novo or recurrent hepatocellular carcinoma(hcc) post transplant
boolean
C2239176 (UMLS CUI [1,1])
C1515568 (UMLS CUI [1,2])
C0861876 (UMLS CUI [2,1])
C0023911 (UMLS CUI [2,2])
Current use of corticosteroids, prednisone equivalent daily dose
Item
current use of corticosteroids at any dose > 5mg of prednisone/day (or equivalent dose of corticosteroid)
boolean
C0001617 (UMLS CUI [1,1])
C2348070 (UMLS CUI [1,2])
C0032952 (UMLS CUI [1,3])
C0205163 (UMLS CUI [1,4])
C0521116 (UMLS CUI [1,5])
Hepatitis b virus surface antigen positive | HIV test positive
Item
infection with hepatitis b virus (hbv) or hiv at screening
boolean
C0019168 (UMLS CUI [1,1])
C1446409 (UMLS CUI [1,2])
C1321876 (UMLS CUI [2,1])
C1446409 (UMLS CUI [2,2])
Current, uncontrolled ascites | Variceal hemorrhage | Hepatic encephalopathy | Hepatorenal syndrome | Hepatopulmonary syndrome | Other signs of decompensated cirrhosis
Item
current, uncontrolled ascites, variceal hemorrhage, hepatic encephalopathy, hepatorenal syndrome, hepatopulmonary syndrome, or other signs of decompensated cirrhosis
boolean
C0003962 (UMLS CUI [1,1])
C0205318 (UMLS CUI [1,2])
C0521116 (UMLS CUI [1,3])
C0333106 (UMLS CUI [2,1])
C0521116 (UMLS CUI [2,2])
C0019151 (UMLS CUI [3,1])
C0521116 (UMLS CUI [3,2])
C0019212 (UMLS CUI [4])
C0600452 (UMLS CUI [5])
C1394798 (UMLS CUI [6,1])
C0521116 (UMLS CUI [6,2])
C0037088 (UMLS CUI [6,3])
C0205394 (UMLS CUI [6,4])