Heart failure due to ischemic, idiopathic or hypertensive causes | New York Heart Association | Duration Minumum
Item
american heart association stage b-d heart failure due to ischemic, idiopathic or hypertensive causes, present for at least 3 months
boolean
C0018801 (UMLS CUI [1,1])
C1275491 (UMLS CUI [1,2])
C0475224 (UMLS CUI [1,3])
C0449238 (UMLS CUI [1,4])
C1524031 (UMLS CUI [1,5])
C0018801 (UMLS CUI [2,1])
C1275491 (UMLS CUI [2,2])
C0332240 (UMLS CUI [2,3])
C0449238 (UMLS CUI [2,4])
C1524031 (UMLS CUI [2,5])
C0018801 (UMLS CUI [3,1])
C1275491 (UMLS CUI [3,2])
C0678226 (UMLS CUI [3,3])
C0020538 (UMLS CUI [3,4])
C0449238 (UMLS CUI [3,5])
C1524031 (UMLS CUI [3,6])
Left ventricular ejection fraction decreased
Item
left ventricular ejection fraction ≤ 45 %
boolean
C0743400 (UMLS CUI [1])
Optimal medical therapy for heart failure
Item
optimal medical therapy for heart failure
boolean
C0018801 (UMLS CUI [1,1])
C0087111 (UMLS CUI [1,2])
C2698651 (UMLS CUI [1,3])
No change recent of cardiac medication | Betablockers minimal duration
Item
no change in active cardiac medications for 2 weeks prior to randomization, beta-blockers must be started 3 months prior to randomization
boolean
C0332197 (UMLS CUI [1,1])
C0580105 (UMLS CUI [1,2])
C0018787 (UMLS CUI [1,3])
C0332185 (UMLS CUI [1,4])
C0304516 (UMLS CUI [2,1])
C0449238 (UMLS CUI [2,2])
C1524031 (UMLS CUI [2,3])
Sleep apnea with AHI ≥ 15 | Obstructive sleep apnea with an epworth sleepiness scale score of ≤ 10 and no or mild daytime sleepiness
Item
sleep apnea with an ahi ≥ 15. subjects with obstructive sleep apnea must also have an epworth sleepiness scale score of ≤ 10 and no or mild daytime sleepiness
boolean
C0037315 (UMLS CUI [1,1])
C4083070 (UMLS CUI [1,2])
C0520679 (UMLS CUI [2,1])
C3541276 (UMLS CUI [2,2])
C0332169 (UMLS CUI [2,3])
C0013144 (UMLS CUI [2,4])
C2945599 (UMLS CUI [2,5])
C0520679 (UMLS CUI [3,1])
C3541276 (UMLS CUI [3,2])
C0332169 (UMLS CUI [3,3])
C0013144 (UMLS CUI [3,4])
C0332197 (UMLS CUI [3,5])
Informed consent
Item
written informed consent
boolean
C0021430 (UMLS CUI [1])
Heart failure due to primary valvular heart disease
Item
heart failure due to primary valvular heart disease
boolean
C0018801 (UMLS CUI [1,1])
C0678226 (UMLS CUI [1,2])
C0018824 (UMLS CUI [1,3])
C0205225 (UMLS CUI [1,4])
Moderate to severe mitral insuficiency due to intrinsic mitral valve disease
Item
presence of moderate to severe mitral insufficiency due to intrinsic mitral valve disease
boolean
C0026266 (UMLS CUI [1,1])
C1299393 (UMLS CUI [1,2])
C0678226 (UMLS CUI [1,3])
C0439674 (UMLS CUI [1,4])
C0026265 (UMLS CUI [1,5])
Hypertrophic obstructive cardiomyopathy | Restrictive cardiomyopathy | Post partum cardiomyopathy
Item
hypertrophic obstructive or restrictive or post partum cardiomyopathy
boolean
C0007194 (UMLS CUI [1])
C0007196 (UMLS CUI [2])
C0687676 (UMLS CUI [3,1])
C1148523 (UMLS CUI [3,2])
C0878544 (UMLS CUI [3,3])
Exercise capacity limited by class iv angina pectoris
Item
exercise capacity limited by class iv angina pectoris
boolean
C0015259 (UMLS CUI [1,1])
C0439801 (UMLS CUI [1,2])
C0678226 (UMLS CUI [1,3])
C0002962 (UMLS CUI [1,4])
C0008902 (UMLS CUI [1,5])
Recent acute mi | Cardiac surgery | pci | aicd | crt
Item
acute mi, cardiac surgery, pci, aicd, or crt within 3 months of randomization
boolean
C0155626 (UMLS CUI [1,1])
C0332185 (UMLS CUI [1,2])
C0018821 (UMLS CUI [2,1])
C0332185 (UMLS CUI [2,2])
C1532338 (UMLS CUI [3,1])
C0332185 (UMLS CUI [3,2])
C0972395 (UMLS CUI [4,1])
C0332185 (UMLS CUI [4,2])
C1167956 (UMLS CUI [5,1])
C0332185 (UMLS CUI [5,2])
Myocarditis
Item
active myocarditis
boolean
C0027059 (UMLS CUI [1])
Planned aicd or crt
Item
planned aicd or crt
boolean
C0972395 (UMLS CUI [1,1])
C1301732 (UMLS CUI [1,2])
C1532338 (UMLS CUI [2,1])
C1301732 (UMLS CUI [2,2])
Left-ventricular assist device
Item
presence of a left-ventricular assist device
boolean
C0181598 (UMLS CUI [1])
Transplanted heart | Expected to receive a transplanted heart
Item
transplanted heart or expected to receive a transplanted heart within the next 6 months
boolean
C2029943 (UMLS CUI [1])
C0018823 (UMLS CUI [2,1])
C1517001 (UMLS CUI [2,2])
Pregnancy
Item
pregnancy
boolean
C0032961 (UMLS CUI [1])
Current use of ASV | Current use of CPAP | Recent investigational therapy
Item
current use of asv or cpap or treated with any investigational therapy during the last 4 weeks (including approved therapies being used in unapproved indications)
boolean
C0521116 (UMLS CUI [1,1])
C4285752 (UMLS CUI [1,2])
C0521116 (UMLS CUI [2,1])
C0199451 (UMLS CUI [2,2])
C0949266 (UMLS CUI [3,1])
C0332185 (UMLS CUI [3,2])
A clinical history that would interfere with the objectives of this stady or that would in the investigator's opinion preclude safe conclusion of the study
Item
a clinical history that would interfere with the objectives of this study or that would in the investigator's opinion preclude safe conclusion of the study
boolean
C0262926 (UMLS CUI [1,1])
C0521102 (UMLS CUI [1,2])
C0018017 (UMLS CUI [1,3])
C0008976 (UMLS CUI [1,4])
C0262926 (UMLS CUI [2,1])
C0521102 (UMLS CUI [2,2])
C0035173 (UMLS CUI [2,3])
C0871010 (UMLS CUI [2,4])
C0332197 (UMLS CUI [2,5])
C0036043 (UMLS CUI [2,6])
Other medical, social, or geographical factor, which would make it unlikely that the patient will comply with the study procedures
Item
any other medical, social, or geographical factor, which would make it unlikely that the patient will comply with the study procedures (e.g. alcohol abuse, lack of permanent residence, severe depression, disorientation, distant location, or history of non-compliance)
boolean
C0525058 (UMLS CUI [1,1])
C0750558 (UMLS CUI [1,2])
C0678226 (UMLS CUI [1,3])
C0205476 (UMLS CUI [1,4])
C0348080 (UMLS CUI [1,5])
C0525058 (UMLS CUI [2,1])
C0750558 (UMLS CUI [2,2])
C0678226 (UMLS CUI [2,3])
C0748872 (UMLS CUI [2,4])
C0348080 (UMLS CUI [2,5])
C0525058 (UMLS CUI [3,1])
C0750558 (UMLS CUI [3,2])
C0678226 (UMLS CUI [3,3])
C1517526 (UMLS CUI [3,4])
C0348080 (UMLS CUI [3,5])
Contraindication to asv therapy as detailed in the device provider manual
Item
any contraindication to asv therapy as detailed in the device provider manual
boolean
C1301624 (UMLS CUI [1,1])
C4285752 (UMLS CUI [1,2])
C0025080 (UMLS CUI [1,3])
C1442085 (UMLS CUI [1,4])